Clinical trials: Upper Limb Surgery
Lymphedema, Seroma
Breaststroke Swimming After Breast Cancer Treatment/Surgery as a Means of Treatment for Seroma, Lymphedema, and Chronic Arm and Chest Pain
Following surgery and treatment for breast cancer, many patients experience swelling of lymph nodes (lymphedema) or accumulation of fluid (seroma) that can cause pain, restrict movement, and reduce quality of life.
- Conditions
- Lymphedema, Seroma, Pain, Postoperative, Pain, Chest
- Trial name
- NCT04080934
- Testing
- Swimming
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Ottawa Hospital Research Institute
Spinal Lumbar Stenosis, Claudication, Intermittent
Evaluation of Safety and Effectiveness of Lobster Dynamic Interspinous Spacer in Lumbar Spinal Stenosis
The aim of this study is to demonstrate the safety and effectiveness of the Lobster interspinous spacer device for the treatment of Lumbar Spinal Stenosis in comparison to an SSED-based performance goal.
- Trial name
- LB2CT01 (NCT05587465)
- Testing
- Lobster Device
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Diametros Medical srl
Osteomyelitis
Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin.
The purpose of this trial is to determine if genex with gentamicin (genex G) an antibiotic loaded bone void filler, works to treat and is a safe option as part of the surgical treatment of osteomyelitis in the extremities.
- Trial name
- ADOPT GG (NCT07270380)
- Testing
- genex with gentamicin (genex G)
- Where
- 4 sites in United States
- Volunteers
- 139 people
- Sponsor
- Biocomposites Ltd
Tetraplegia
Elbow Extension Restoration Surgery in People With Tetraplegia: Evolution of the Muscular Co-activations of the Upper Limb During the Post-operative Rehabilitation
Patients with C5 or C6 tetraplegia have paralysis of the triceps brachii. Elbow extension can be surgically restored by transferring the tendon from a preserved muscle onto the tendon of the paralyzed triceps brachii.
- Trial name
- MouvSupReaTetr (NCT03513783)
- Testing
- measurement of human movement
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Nantes University Hospital
Radius Fracture Distal, Rebound Pain
Ropivacaine Concentration and Rebound Pain
The goal of this clinical trial is to see if the concentration of a local anesthetic (ropivacaine) in peripheral nerve block is related to the severness of pain after surgery of distal radius fractures in adults.
- Trial name
- NCT06950372
- Testing
- Ropivacaine concentration low, Ropivacaine concentration high
- Where
- Norway
- Volunteers
- 80 people
- Sponsor
- Oslo University Hospital
Arm Injury
Plasma Concentration of Lidocaine and Bupivacaine Axillary BPB Mixture Solutions [PCLBAxMix]
The doses of local anesthetics can be decreased with the use of ultrasound guidance. In case of using mixture solutions the benefits and drawbacks are controversial.
- Trial name
- PCLBAxMix (NCT03527836)
- Testing
- Lidocaine brachial plexus block, Bupivacaine brachial plexus block, Mixture brachial plexus block
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- University of Pecs
Cervical Cancer, Immunochemotherapy
Chemo-immunotherapy for Cervical Cancer Stage IIICp Trial
Efficacy evaluation of camrelizumab combined with chemotherapy for adjuvant treatment of patients with pathologically confirmed lymph node-positive cervical cancer after staging surgery.
- Trial name
- NCT07167160
- Testing
- Camrelizumab combined with chemotherapy
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Surgery, Stomach Cancer
TRANScriptional Pathways Of Surgical Pain Modulated by Music Therapy Exposure (TRANSPOSE)
Participants may take part in this study if they are scheduled to undergo a surgery that meets the following: (1) traditional open surgery via laparotomy, (2) length of surgery >3 hours, and (3) curative-intent surgical resection…
- Conditions
- Surgery, Stomach Cancer, Pancreas Cancer, Bile Duct Cancer
- Trial name
- NCT07653594
- Testing
- Music-assisted relaxation and imagery (MARI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Case Comprehensive Cancer Center
Breast Cancer, Recurrent Breast Cancer
Local Treatment in ER-positive/HER2-negative Oligo-metastatic Breast Cancer
Local treatment in addition to endocrine treatment as 1st line for oligo-metastatic ER-positive/HER2-negative breast cancer.
- Conditions
- Breast Cancer, Recurrent Breast Cancer, Stereotactic Body Radiotherapy, Estrogen Receptor Positive Tumor
- Trial name
- CLEAR (NCT03750396)
- Testing
- Surgical resection, Stereotactic body radiotherapy, Radiofrequency ablation
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Gangnam Severance Hospital
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Vitrectomy
A Study to Evaluate the Safety and Performance of the Vista Probe for Vitrectomy Surgery
This is a prospective, single-arm, non-comparative, open-label, monocular, post approval study to assess safety and device performance of the Vista Vitrectomy Probe during vitrectomy surgery.
- Trial name
- NCT05689333
- Testing
- Vista Vitrectomy Probe
- Where
- 4 sites in United States
- Volunteers
- 32 people
- Sponsor
- VISTA Ophthalmics
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Upper Limb Surgery
Ultrasound-guided Versus Blind Technique in Medial Brachial Cutaneous Nerve and Intercostobrachial Nerve Blocks
The axillary brachial plexus block is a technique of locoregional anesthesia indicated in the distal upper limb surgery : hand, forearm, the lower third of the arm including the elbow.
- Trial name
- ECHO_NCMB (NCT02940847)
- Testing
- medial brachial cutaneous nerve block and intercostobrachial nerve block with blind technique, medial brachial cutaneous nerve block and intercostobrachial nerve block with ultrasound-guided technique
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Post Operative Pain, Anesthesia
Dexmedetomidine and Dexamethasone Added as Adjuvant Infraclavicular Brachial Plexus Block in Upper Limb Surgery
The aim of this study was to investigate the effect of dexmedetomidine and dexamethasone added during USG-guided infraclavicular block on block onset time, total block time and time to first analgesic need in patients undergoing…
- Conditions
- Post Operative Pain, Anesthesia, Acute Pain
- Trial name
- NCT06779604
- Testing
- Infraclavicular Block with Dexmedetomidine and Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Umraniye Education and Research Hospital
Adenocarcinoma, Lung Neoplasm
Efficacy and Safety of Adjuvant Pemetrexed Plus Cisplatin for Adenocarcinoma of Lung
Two-Year Disease Free Survival Rate of Stage IB~IIIA adenocarcinoma after Adjuvant Chemotherapy with Pemetrexed and Cisplatin will be assessed.
- Trial name
- APICAL (NCT02498860)
- Testing
- Pemebit, Cisplatin
- Where
- 7 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Chonnam National University Hospital
Distal Radius Fractures
Treatment of Distal Radius Fractures in Elderly Patients
The purpose of this study is to create and test a treatment algorithm to guide the treatment of distal radius fractures in patients 65 and older and to obtain level-one evidence to determine the best method of treating distal…
- Trial name
- NCT00788190
- Testing
- Distal Radius Fracture Reduction, Conservative Management
- Where
- 2 sites in Canada
- Volunteers
- 65 people
- Sponsor
- Hand and Upper Limb Clinic, Canada
Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
A Prospective, Single-arm, Trial to Determine Contamination Rates When Using an Antibacterial Incise Drape During Orthopedic Surgery
The goal of this clinical study is to generate data on the intended use of a chlorhexidine gluconate (CHG)-impregnated antimicrobial incise drape.
- Trial name
- NCT07356323
- Testing
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- Solventum US LLC
Obesity, Morbidly Obese
Novel SaCoVLM™ Video Laryngeal Mask Airway as an Intubation Conduit in Morbidly Obese Bariatric Surgery
Background: The SaCoVLM™ video laryngeal mask is a novel video-assisted device that integrates the functions of both a dual-channel laryngeal mask airway (LMA) and an intubating laryngeal mask airway (ILMA).
- Trial name
- NCT07573813
- Testing
- SaCoVLM™ in Difficult Airways
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Yongtao Sun
Perioperative Recovery, Prehabilitation
Web-based Home Multimodal Prehabilitation for Patients Undergoing Major Surgeries
Prehabilitation is the process of optimizing physical functionality preoperatively to enable the individual to maintain a normal level of function during and after surgery.
- Trial name
- NCT05324345
- Testing
- Prehabilitation group
- Volunteers
- 40 people
- Sponsor
- Peking Union Medical College Hospital
Bladder Cancer
A Study of Intravesical Apaziquone as a Surgical Adjuvant in Participant Undergoing Transurethral Resection Bladder Tumor (TURBT)
This is a Phase 3, randomized, multicenter, multi-arm, placebo-controlled, double-blind study of apaziquone in participants with ≤4 non-muscle invasive bladder cancer (NMIBC), ≤3.5 centimeters (cm) in diameter, all of which must…
- Trial name
- NCT02563561
- Testing
- Apaziquone
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Spectrum Pharmaceuticals, Inc