Clinical trials: Upper Limb Surgery
Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy
Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer
Main Purpose of this study is to determine the efficacy and safety of Cadonilimab combined with chemotherapy (cisplatin) for locally advanced cervical cancer.
- Conditions
- Female, Age ≥ 18 Years Old, No Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy, ECOG Score of 0-1, Histologically Confirmed Cervical Cancer, FIGO Stage IB3, IIA2, IIB, IIIC, and Assessed by the Researcher as Resectable Lesion
- Trial name
- NCT07104149
- Testing
- Cadonilimab combined with cisplatin
- Where
- China
- Volunteers
- 29 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Complex Regional Pain Syndromes, Distal Radius Fractures
Prednisone for CRPS in Distal Radius Fracture
Wrist fractures are the most prevalent adult fracture. Complex regional pain syndrome (CRPS) is a common complication that can occur, leading to permanent disability and is costly to the patient and healthcare system.
- Trial name
- NCT06453447
- Testing
- Prednisone
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Glioma
Study of Intraparenchymal Therapy With Irinotecan Drug Eluting Beads as Adjunct to Recurrent Surgically Resectable High Grade Glioma
A study to demonstrate safety, and feasibility for intraparenchymal injection of irinotecan hydrochloride drug-eluting beads in the treatment of recurrent high grade glioma (HGG).
- Trial name
- IDEB-glioma (NCT02481960)
- Testing
- CM-BC2 Irinotecan drug-eluting bead
- Where
- 2 sites in France, Germany
- Volunteers
- 5 people
- Sponsor
- Boston Scientific Corporation
C5 Palsy
Conventional-therapy & FES-therapy In-Veritas Effects Study
This randomized clinical trial will primarily compare the effectiveness of conventional physiotherapy alone with combined conventional physiotherapy and FES-t along with task-specific training in terms of the improvement of the…
- Trial name
- C-FIVE (NCT05247450)
- Testing
- Functional electrical stimulation therapy (FES-t), Conventional physiotherapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Edema Limbs
Effects Neuromuscular Taping Technique on Upper Limbs Edema in Cardiac Surgery Patients
This study aims to verify the efficacy of the decompression technique of neuromuscular taping on cardiac surgery patients in whom edema of the upper limbs occurs due to post-operative water overload.
- Trial name
- NCT04785508
- Testing
- neuromuscolar tape, antigravity arm position
- Where
- Italy
- Volunteers
- 10 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hemorrhage, Blood Loss
Clinical Investigation Evaluating a New Autotransfusion Device in Cardiac Surgery
Blood transfusion is at the heart of the therapeutic arsenal when there is a hemorrhage and/or blood loss during a surgery. There are two types of transfusion: the homologous one (blood from a compatible donor) and the autologous…
- Conditions
- Hemorrhage, Blood Loss, Surgical Blood Loss
- Trial name
- i-TRANSEP (NCT04588350)
- Testing
- i-SEP autotransfusion system
- Where
- 5 sites in France
- Volunteers
- 50 people
- Sponsor
- i-SEP
Breast Cancer, Upper Extremity Dysfunction
KİNECT® - Video Games Based Physiotherapy Programme in Patients With Breast Cancer Surgery
The main objective of the study is to investigate the effects of Kinect® video based technology on pain, functionality, muscle strength, fatigue and quality of life in patients with breast cancer surgery and axillary node…
- Conditions
- Breast Cancer, Upper Extremity Dysfunction, Mastectomy
- Trial name
- NCT03618433
- Testing
- study group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Acibadem University
Fracture, Radius Fracture Distal
Wrist Arthroscopy During Surgical Treatment of Distal Radius Fractures
Wrist arthroscopy (WA) is a potentially useful adjuvant procedure in the surgical treatment (osteosynthesis) of distal radius fractures (DRFs).
- Trial name
- NCT05580848
- Testing
- Wrist arthroscopy
- Volunteers
- 56 people
- Sponsor
- Clinic for Orthopedics Lovran
Bone Mineral Density, Primary Implant Stability
Digital Eye®-Assisted Bone Density Classification and Primary Dental Implant Stability.
Dental implants are used nowadays to replace extracted teeth. They provide a successful substitute for lost teeth. Accurate planning prior to implant placement is very important.
- Conditions
- Bone Mineral Density, Primary Implant Stability, Digital Eye Bone Density Assessment, Site-specific Drilling Protocol
- Trial name
- NCT07899606
- Testing
- R2GATE Digital EYE-Assisted Site-Specific Drilling Protocol, R2GATE® Digital EYE® Implant Planning Software, MEGA ISQ® - Implant Stability Measurement Device
- Where
- Jordan
- Volunteers
- 60 people
- Sponsor
- King Abdullah University Hospital
ENT Disorder, Nasal Procedures
Pharmacokinetics, Safety, and Tolerability Study of GOPRELTO® Nasal Solution and NUMBRINO™ Nasal Solution
The purpose of this study is to assess the pharmacokinetic (PK) properties, safety and tolerability following a single dose administration of GOPRELTO® or NUMBRINO™ as an anesthetic for diagnostic procedures and surgeries on or…
- Conditions
- ENT Disorder, Nasal Procedures, Nasal Anesthesia, Nasal Mucosa Surgery
- Trial name
- NCT04792034
- Testing
- Cocaine Hydrochloride Nasal Solution
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- LXO Ireland
Anesthesia
Comparison of Costoclavicular and Paracoracoid Approaches to Infraclavicular Brachial Plexus Blocks
Infraclavicular block has taken its place in the literature as a proven technique in the anesthetic management of upper extremity surgeries.
- Trial name
- NCT05260736
- Testing
- Infraclavicular brachial plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University
Pancreatic Cancer
Vaccine Therapy With or Without Cyclophosphamide in Treating Patients Undergoing Chemotherapy and Radiation Therapy for Stage I or Stage II Pancreatic Cancer That Can Be Removed by Surgery
RATIONALE: Vaccines made from gene-modified tumor cells may help the body build an effective immune response to kill pancreatic cancer cells.
- Trial name
- NCT00727441
- Testing
- GVAX pancreatic cancer vaccine, cyclophosphamide
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Epicondylitis of the Elbow, Tennis Elbow
Tendon Fenestration Versus Surgery for the Treatment of Chronic Lateral Epicondylosis
Lateral epicondylosis, also called tennis elbow or lateral epicondylitis, is a prevalent, painful syndrome of the elbow. It is refractory to conservative treatment measures, including rest, excentric and concentric exercises in…
- Trial name
- NCT02710682
- Testing
- Mini-open surgery, Ultrasound-guided Tendon fenestration
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Abdominal Surgery, Colon Surgery
D-PLEX 310: Safety and Efficacy of D-PLEX in the Prevention of Post Abdominal Surgery Incisional Infection
Subjects who are planned to undergo an abdominal (colon) surgery and who will meet the study entry criteria will be randomly divided into 2 groups: for half D-PLEX will be administered concomitantly with the standard of care…
- Conditions
- Abdominal Surgery, Colon Surgery, Post-Op Infection
- Trial name
- NCT03633123
- Testing
- D-PLEX, Standard of Care (SoC)
- Where
- 8 sites in Israel
- Volunteers
- 202 people
- Sponsor
- PolyPid Ltd.
Non-Small Cell Lung Cancer
Exploratory Study of QBKPN SSI in Non-Small Cell Lung Cancer
The purpose of this study is to evaluate the safety, tolerability, compliance and mechanism of action of study drug (QBKPN SSI) in subjects with two or more second primary pre-invasive or invasive adenocarcinoma following…
- Trial name
- NCT02256852
- Testing
- QBKPN SSI
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Qu Biologics Inc.
Laparotomy
Abdominal Wall Closure After Laparotomy in Oncologic Surgery
The REBUILD Study is a first-in-human evaluation of the safety and performance of REBUILD Bioabsorbable.
- Trial name
- REBUILD (NCT05041530)
- Testing
- REBUILD Bioabsorbable
- Where
- 2 sites in Colombia
- Volunteers
- 30 people
- Sponsor
- AbSolutions Med Inc.
Lymphedema, Edema
LymphBridge: Surgical Evaluation for Breast Cancer-Associated Lymphedema (BioBridge)
To investigate whether the addition of Fibralign's BioBridge® Collagen Matrix (BioBridge) devices to the standard surgery for vascularized lymph node transfer will improve the outcome of surgical treatment in lymphedema of the…
- Trial name
- NCT04606030
- Testing
- BioBridge® Collagen Matrix, Vascularized Lymph Node Transfer (VLNT)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Fibralign Corporation
Hip Fractures
Pre- and Post-Operative Exercise in Patients With Hip Fracture
The purposes of this study are to determine the benefits of a pre-operative aerobic exercise program and an 8-week postoperative aerobic exercise program with a portable upper extremity cycle-ergometer in patients with hip…
- Trial name
- NCT05389800
- Testing
- Upper Extremity Aerobic Exercise
- Where
- Greece
- Volunteers
- 116 people
- Sponsor
- National and Kapodistrian University of Athens
Lung Cancer Metastatic, Surgical Resection
Primary Tumor Resection for M1a Stage Lung Cancer
This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1023. This study aims to explore the safety and efficacy of primary lesion resection in the treatment of M1a stage lung cancer…
- Trial name
- ECTOP-1023 (NCT06547710)
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Fudan University
Upper Limb Injury
Adjuvants for Bupivacaine in Brachial Plexus Block in Pediatrics
Among paediatrics aging 3:12 who are going to have upper limb surgery,does adding clonidine to bupivacaine improve brachial plexus block outcome in comparison with magnesium sulfate with bupivacaine?
- Trial name
- NCT06180941
- Testing
- magnesium sulfate., clonidine.
- Volunteers
- 70 people
- Sponsor
- Assiut University