Clinical trials: Upper Limb Surgery
Preoperative Anxiety
Effectiveness of Virtual Reality-enhanced Interventions on Preoperative Anxiety in Adults Undergoing Elective Surgery
Brief Summary: Preoperative anxiety is a common phenomenon in surgical patients, with a pooled global prevalence of 48%. Surgical patients with preoperative anxiety may negatively impact their psychological health and surgical…
- Trial name
- VIPA (NCT07379450)
- Testing
- Virtual Reality
- Where
- Hong Kong
- Volunteers
- 270 people
- Sponsor
- Sin Lun CHAN
Pediatric Patients, Orthopedic Surgery
Nociception Level Index as a Verbal Tool of Pain in Children
60 children under 6 years old, scheduled for orthopedic surgery for limb fracture or neuromuscular and bone deformities will be randomized by closed envelope method into two groups (n=30) either receiving standard pain management…
- Conditions
- Pediatric Patients, Orthopedic Surgery, Extremity Fractures Lower, Extremity Fractures Upper
- Trial name
- NCT05716243
- Testing
- The nociception level index monitorization, The nociception level index measurement;postoperative
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Haseki Training and Research Hospital
MSI-H, PD-1 Immunotherapy
PD-1 Antibody Adjuvant Therapy for GC Patients With MSI-H After D2 Radical Surgery
Approximately 5% to 10% of gastric cancers have MSI-H/dMMR. According to the results of retrospective analysis of CLASSIC and MAGIC, MSI-H/dMMR was a good prognosis and potential negative predictor of adjuvant chemotherapy for…
- Conditions
- MSI-H, PD-1 Immunotherapy, Gastric Cancer, Adjuvant Therapy
- Trial name
- NCT05468138
- Testing
- SOX, XELOX, PD-1 antibody
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Fudan University
Vascular Anastomosis Surgery
Post-market Clinical Study to Confirm Safety and Performance of PuraStat® for the Management of Bleeding in Vascular Surgery.
The objective of this post-market clinical follow-up study is to collect medical information on patients implanted with PuraStat®, according to each participating institution's procedures and standards of care.
- Trial name
- NCT03103282
- Testing
- PuraStat®
- Where
- United Kingdom
- Volunteers
- 65 people
- Sponsor
- 3-D Matrix Europe SAS
Post-Surgical Ocular Pain, Post-Surgical Ocular Inflammation
OTX-14-003: A Phase 3 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Ocular Inflammation and Pain After Cataract Surgery
The objective of the study was to evaluate the safety and efficacy of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of post-surgical inflammation and…
- Trial name
- NCT02089113
- Testing
- Dexamethasone
- Volunteers
- 241 people
- Sponsor
- Ocular Therapeutix, Inc.
Cutaneous Squamous Cell Carcinoma
Neoadjuvant Plus Adjuvant Treatment With Cemiplimab in Cutaneaous Squamous Cell Carcinoma
Neoadjuvant plus adjuvant treatment with immunotherapy may have an anti-tumor activity and reduce the risk of relapse in patients with high risk surgically resectable stage III cutaneous squamous cell carcinoma.
- Trial name
- NCT04632433
- Testing
- Cemiplimab
- Where
- 7 sites in Italy
- Volunteers
- 25 people
- Sponsor
- Fondazione Melanoma Onlus
Stage III NSCLC, Surgery
Induction Lorlatinib in Stage III Non-small Cell Lung Cancer
A prospective, single-arm, open-label phase 2 study that evaluates the efficacy and safety of induction Lorlatinib in stage III non-small cell lung cancer and explores the clinical feasibility of dynamic ctDNA and…
- Trial name
- NCT05740943
- Testing
- Lorlatinib
- Where
- 4 sites in China
- Volunteers
- 48 people
- Sponsor
- Guangdong Provincial People's Hospital
Stomach Neoplasms
Enhanced Recovery After Surgery (ERAS) on Laparoscopy-assisted Distal Gastrectomy
This study evaluates the safety and effectiveness of enhanced recovery after surgery(ERAS) on laparoscopic distal gastrectomy for gastric cancer.All of participants received an ERAS program.
- Trial name
- NCT03016026
- Testing
- ERAS
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Breast Cancer Surgery, Reconstruction Breast Surgery
Improvement in Breast Skin Sensibility After Breast Reconstruction: a Comparison of 3 Surgical Techniques
The goal of this clinical trial is to learn if nerve sutures in free flap breast reconstruction can optimize sensibility in the reconstructed breast in patients opting for DIEP flap breast reconstruction due to breast cancer or…
- Conditions
- Breast Cancer Surgery, Reconstruction Breast Surgery, Sensitization, DIEP Flap Breast Reconstruction
- Trial name
- S-DIEP (NCT06930378)
- Testing
- Nerve Suture
- Where
- Switzerland
- Volunteers
- 63 people
- Sponsor
- Patricia Esther Engels
Cerebral Palsy, Muscle
How Are the Muscles Affected in Cerebral Palsy? A Study of Muscle Biopsies Taken During Orthopaedic Surgery.
Cerebral palsy (CP) is a motor disorder caused by an injury to the immature brain. Even though the brain damage does not change, children with CP will have progressively weaker, shorter and stiffer muscles that will lead to…
- Conditions
- Cerebral Palsy, Muscle, Muscle Contracture, Muscle Spasticity
- Trial name
- CPTDBiopsy (NCT05506228)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eva Ponten
Humerus Fracture
Surgical Treamtment of Pseudarthrosis of the Humerus (Study of a Series of 53 Cases)
Pseudarthrosis of the humerus is a serious complication of humerus fractures, of particular interest to subjects young working people with pseudoarthrogenic risk factors (tobacco++).
- Trial name
- NCT06360848
- Testing
- surgery
- Volunteers
- 53 people
- Sponsor
- Ibn Jazzar Hospital
Breast Cancer, Chronic Pain
Reducing Pain and Disability After Breast Cancer Surgery
The purpose of this study is to determine if the combination of thoracic paravertebral block and multimodal analgesia will decrease chronic pain and arm morbidity in patients undergoing breast cancer surgery with lymph node…
- Trial name
- RELIeF (NCT01089933)
- Testing
- Thoracic Paravertebral Block (TPVB), Local Anesthetic
- Where
- Canada
- Volunteers
- 129 people
- Sponsor
- Ottawa Hospital Research Institute
Liver Resection
Post-Market Clinical Study to Confirm Safety and Performance of PuraStat Absorbable Haemostatic Material for the Management of Bleeding in Liver Surgery
The objective of this post-market clinical follow-up study is to collect medical information on patients implanted with PuraStat®, according to each participating institution's procedures and standards of care.
- Trial name
- NCT03600168
- Testing
- PuraStat®
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- 3-D Matrix Europe SAS
Cutaneous Breast Cancer
Efficacy and Safety Study of REM-001 Photodynamic Therapy for Treatment of Cutaneous Metastatic Breast Cancer (CMBC)
This is an open-label, single cohort study to confirm dose, assessments and timing of response, to support future studies. The primary objective of the trial is to evaluate cutaneous tumor response within total target treatment…
- Trial name
- NCT05374915
- Testing
- REM-001 photodynamic therapy
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Kintara Therapeutics, Inc.
Giant Cell Tumor of Bone
Efficacy and Safety of JMT103 in Patients With Giant Cell Tumor of Bone
This is a phase Ib/II, multicenter, single-arm, open-label study to evaluate the efficacy and safety of JMT103 in patients with surgically unsalvageable or refractory giant cell tumor of bone (GCTB).
- Trial name
- NCT04255576
- Testing
- Dietary Supplement: Calcium/Vitamin D
- Where
- China
- Volunteers
- 139 people
- Sponsor
- Shanghai JMT-Bio Inc.
Pain, Acute, Postoperative Pain
Bupivacaine Versus Bupivacaine Plus Lidocaine in Infraclavicular Block
In this study, the investigators will compare two different anesthetic solutions in the infraclavicular block in patients having forearm, wrist, and hand surgery.
- Conditions
- Pain, Acute, Postoperative Pain, Analgesia
- Trial name
- NCT05834023
- Testing
- Bupivacaine-Lidocaine, Bupivacaine
- Where
- Chile
- Volunteers
- 40 people
- Sponsor
- Hospital de San Carlos Dr. Benicio Arzola Medina
Breast Cancer Female, Breast Cancer Lymphedema
The Effect of Arm Exercises on Arm Oedema After Breast Cancer Surgery
In order to prevent lymphedema after breast surgery, patients are advised to know the risk factors for lymphedema and to avoid situations that may cause lymphedema, to perform active and passive arm exercises, to evaluate the…
- Trial name
- NCT05303675
- Testing
- exercise and training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gulseren MARAS
General Anesthesia Induction for Elective Surgery, Sono Guided Catheterization
Sonographic Safety Margins of Subclavian Vein: Effect of View and Arm Position
The purpose of this observational study is to evaluate and compare the anatomical safety margins of the subclavian vein using ultrasound.
- Trial name
- NCT07556770
- Testing
- Non-invasive sonographic observation
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Asan Medical Center
Elbow Joint Contracture, Elbow Flexion Contractures
The Posttraumatic Elbow Stiffness Treatment
This study compares patients with post traumatic elbow stiffness and evaluate the range of motion improvement with two types of treatment: surgical release versus non-surgical rehabilitation protocol with orthoses.
- Conditions
- Elbow Joint Contracture, Elbow Flexion Contractures, Elbow Injury, Elbow Osteoarthritis
- Trial name
- NCT03015415
- Testing
- Elbow Open Arthrolyses, Non-surgical intervention
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Open Angle Glaucoma, Ocular Hypertension
Travoprost Intraocular Implant in Conjunction With Cataract Surgery
Subjects with cataract requiring extraction and who have open-angle glaucoma or ocular hypertension will undergo screening and washout from IOP-lowering medication, if applicable.
- Trial name
- NCT06061718
- Testing
- iDose TR
- Where
- Armenia
- Volunteers
- 60 people
- Sponsor
- Glaukos Corporation