Clinical trials: Upper Limb Surgery
Head and Neck Cancer
Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma
The purpose of this study was to evaluate the safety and tolerability of low-dose radiotherapy plus tislelizumab in combination with afatinib neoadjuvant therapy for patients with surgically resectable squamous carcinoma of the…
- Trial name
- NCT06494189
- Testing
- Tislelizumab, Afatinib, Low dose radiotherapy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- West China Hospital
Mucosal Melanoma, Sinonasal Melanoma
Single Arm Study of Induction Chemoradiotherapy Combined With Surgery in the Treatment of Locally Advanced SNMM
Sinonasal mucosal melanoma (SNMM) is a very rare tumor, and SNMM is highly aggressive in nature, with a 5-year survival rate of about 20~30%.
- Trial name
- SNMM (NCT05009446)
- Testing
- endoscopic surgery, intensity-modulated radiation therapy or volume of rotating intensity-modulated radiotherapy or Proton or heavy ion radiation therapy, Chemotherapy drug
- Where
- China
- Volunteers
- 28 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Squamous Cell Carcinoma
Topical Remetinostat Gel as Neoadjuvant Therapy in Patients With Squamous Cell Carcinoma (SCC)
The primary purpose of this study is to determine if 8 weeks of topical remetinostat applied three times daily will suppress Squamous Cell Carcinoma.
- Trial name
- NCT03875859
- Testing
- Remetinostat
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Kavita Sarin
Kidney Diseases, ESRD
Safety and Efficacy of Angiotech Vascular Wrap Paclitaxel-Eluting Mesh for Hemodialysis Vascular Access
This is a multi-center clinical study in subjects requiring arteriovenous grafts in the upper extremity for hemodialysis access. All subjects will provide informed consent before undergoing any study procedures.
- Trial name
- NCT00448708
- Testing
- Vascular Wrap Paclitaxel-Eluting Mesh, Lifespan® ePTFE Vascular Graft
- Where
- 33 sites in United States
- Volunteers
- 222 people
- Sponsor
- Angiotech Pharmaceuticals
Spinal Tumor, Traumatic Injury of Spine
Study to Evaluate the Safety and Clinical Outcome of Using Navigation System in Pedicle Screw Placement in Spine Surgery
The research project is testing whether in screw insertion of spine surgery using "Anatase" Spine Surgery Navigation System is at least as safe and accurate as using O-arm assisted spine surgery- Medtronic Stealthstation S7…
- Conditions
- Spinal Tumor, Traumatic Injury of Spine, Degenerative Spine Disease
- Trial name
- NCT04578691
- Testing
- "Anatase" Spine Surgery Navigation System, Medtronic Stealthstation S7 Treatment Guidance System
- Where
- Taiwan
- Volunteers
- 55 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Wrist Fracture
Axillary Block in Association With Analgesic Truncal Blocks at the Elbow for Wrist Surgery.
Fractures of the forearm bones that occur around the wrist are common in the elderly. Standard anesthesia for its surgical treatment is regional anesthesia (RA): supraclavicular block, infraclavicular block or axillary block…
- Trial name
- BAXASSO (NCT04046744)
- Testing
- Axillary brachial plexus block with a long-acting local anesthetic, Axillary brachial plexus block with a short-acting local anesthetic + Analgesic block at the elbow with a long-acting local anesthetic, Ropivacaine
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- CMC Ambroise Paré
Distal Radius Fractures
Unstable Fractures of the Distal Radius: Trial of Volar Plate Versus Dorsal Nail Plate Fixation
Fractures of the distal radius are one of the most common orthopaedic injuries and are associated with a high complication rate.
- Trial name
- RADIUS (NCT00848263)
- Testing
- Volar plate, Dorsal nail plate
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Sykehuset Asker og Baerum
Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint
Costs and Consequences of Three Common Orthopedic Procedures on the Upper Extremity
This study compares costs and effectiveness / utility of three common orthopedic surgeries in shoulder and hand from the perspective of the Swiss health system and the clinic.
- Conditions
- Degenerative Arthritis of Left Glenohumeral Joint, Degenerative Arthritis of Right Glenohumeral Joint, Rotator Cuff Tear Arthropathy, Rotator Cuff Tear
- Trial name
- NCT01954433
- Testing
- Operated TSA Patients, Operated RCR Patients, Resection interposition suspension arthroplasty (RISA)
- Where
- Switzerland
- Volunteers
- 450 people
- Sponsor
- Schulthess Klinik
Full- Thickness Massive RCT (MRCT) of at Least 5 cm in Diameter Including Fatty Infiltration Grade III or IV
InSpace™ System in Comparison to Best Repair of Massive Rotator Cuff Tear.
This is a post-marketing study to further assess the safety and effectiveness of the InSpace™ device implantation in comparison to surgical repair of full thickness Massive Rotator Cuff Tear .
- Trial name
- NCT01890733
- Testing
- Best Repair of torn Rotator Cuff, InSpace™ system
- Where
- Italy
- Volunteers
- 5 people
- Sponsor
- OrthoSpace Ltd.
Complex Regional Pain Syndrome I (CRPS I), Nerve Entrapment Syndrome
Median Nerve Decompression for Complex Regional Pain Syndrome: A Clinical Study
This clinical study evaluates the effectiveness of surgical treatment in patients with upper-limb complex regional pain syndrome (CRPS) diagnosed according to the Budapest criteria.
- Trial name
- CRPS-SURG (NCT07263256)
- Testing
- Lesion-Specific Surgical Correction, Median Nerve Decompression
- Where
- Czechia
- Volunteers
- 74 people
- Sponsor
- Jitka Fricova
Male Circumcision, HIV Prevention
Cohort Field Study to Assess the Safety and Efficacy of the PrePex Device for Non-Surgical Circumcision When Performed by Nurses
A range of observational and epidemiological studies have shown that the lifetime risk of HIV infection can be reduced by 70% through male circumcision.
- Trial name
- NCT01434628
- Testing
- PrePex™ device
- Where
- Rwanda
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Rwanda
Solid Tumors, Adult
PANK-003 Cell Injection Combined with Standard Adjuvant Chemotherapy After Surgery in Patients with Solid Tumors
A single-center, single-arm, dose-escalation exploratory clinical trial on the safety and efficacy of PANK-003 cell injection(Peripheral blood-derived allogeneic natural killer cells )combined with standard adjuvant chemotherapy…
- Trial name
- NCT06897228
- Testing
- PANK-003 cell injection
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shenzhen Celconta Life Science Co., Ltd.
Cerebral Palsy, Gait Analysis
Changes in Upper Limb Kinematics in Children With Cerebral Palsy After Lower Limb Surgery
İntroduction The upper limb can be involved in children with cerebral palsy (CP), while the lower limb is more commonly affected.
- Conditions
- Cerebral Palsy, Gait Analysis, Gait Disorders, Neurologic, Gait Disorders in Children
- Trial name
- NCT05957783
- Testing
- Cerebral palsy Gait analysis technique
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Istanbul University
Failed Back Surgery Syndrome
SubQStim: A Post-market Study of Subcutaneous Nerve Stimulation in Failed Back Surgery Syndrome (FBSS) Patients
The purpose of this study is to compare the effectiveness of peripheral nerve stimulation utilizing a subcutaneous lead implant technique (SQS) plus optimized medical management (OMM) versus OMM alone in patients suffering from…
- Trial name
- NCT01711619
- Testing
- subcutaneous nerve stimulation, Optimized Medical Management
- Where
- 26 sites in Australia, Austria and 8 more
- Volunteers
- 162 people
- Sponsor
- MedtronicNeuro
Arm Fracture, Surgical Site Infection
Chlorhexidine and/or Betadine Prep in Pediatric Arm Surgery Following Trauma
There have been numerous studies demonstrating surgical site infections that arise from contamination at time of surgery or by seeding from other sites in the body which arise from organisms normally found on the skin.
- Trial name
- NCT04225065
- Testing
- Chlorhexidine, Betadine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Geisinger Clinic
Liver Metastases, Liver Cancer
TANGO-LIVER Three Arm Nuclear Growth Observation in Liver Surgery
Liver resection is the treatment of choice in patients with malignant liver lesions. Unfortunately, the surgery is not always an option, as in same patients the future remnant liver (FRL) is too small to supply all the functions.
- Conditions
- Liver Metastases, Liver Cancer, Liver Neoplasms, Liver Metastasis Colon Cancer
- Trial name
- TANGO-LIVER (NCT06050200)
- Testing
- PVE, LVD, ALPPS
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Medical University of Warsaw
Cerebral Palsy
Comparison of Tendon Transfer, Botox Injections and Ongoing Treatment in Hemiplegic Cerebral Palsy
Doctors use different treatments for people with Cerebral Palsy. Surgery is one option. Botulinum toxin injections are another option; these are given directly into spastic muscles to weaken them temporarily.
- Trial name
- UECP (NCT00250081)
- Testing
- Upper Extremity Tendon transfer, Botulinum Toxin injections in Upper Extremity, Regularly ongoing therapy
- Where
- 10 sites in United States
- Volunteers
- 38 people
- Sponsor
- Shriners Hospitals for Children
Epithelial Ovarian Cancer, Sentinel Lymph Node Detection
The Application of Sentinel Lymph Node Mapping Technique in the Surgery of Early Epithelial Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to evaluate the feasibility, sensitivity, and specificity of sentinel lymph node (SLN) mapping technology in the population with early epithelial ovarian…
- Trial name
- NCT06673511
- Testing
- Lymph node visualization, No visualization of lymph nodes
- Volunteers
- 246 people
- Sponsor
- Anhui Provincial Hospital
Fracture Elbow
Cast or Operation for Medial Epicondyle Fracture Treatment in Children
This protocol describes a multicenter, prospective randomized and patient preference cohort superiority trial of medial epicondyle fracture treatments comparing functional outcomes between children treated with operative…
- Trial name
- COMET (NCT05131672)
- Testing
- open reduction and internal fixation (ORIF), cast immobilization
- Where
- United States
- Volunteers
- 334 people
- Sponsor
- Joseph Janicki
Scar Tissue, Hypertrophic Scar
Effectiveness of Dry Needling in Linear Scar Tissue
Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging.
- Conditions
- Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar
- Trial name
- NCT06033430
- Testing
- True dry needling
- Where
- 2 sites in United States, Iran
- Volunteers
- 80 people
- Sponsor
- Iran University of Medical Sciences