Clinical trials: Upper Limb Surgery
Head and Neck Cancer
Low-dose Radiotherapy Plus Tislelizumab in Combination With Afatinib for Neoadjuvant Treatment of Surgically Resectable Head and Neck Squamous Carcinoma
The purpose of this study was to evaluate the safety and tolerability of low-dose radiotherapy plus tislelizumab in combination with afatinib neoadjuvant therapy for patients with surgically resectable squamous carcinoma of the…
- Trial name
- NCT06494189
- Testing
- Tislelizumab, Afatinib, Low dose radiotherapy
- Where
- China
- Volunteers
- 9 people
- Sponsor
- West China Hospital
Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children
Clinical Trial on Safety and Efficacy of Thoracoabdominal Endoscopic Surgical System for Pediatric Surgery
This is a prospective, multi-center, single-arm, target-value clinical trial conducted to evaluate the safety and effectiveness of the Thoracic and Abdominal Endoscopic Surgery System (model WJ-SR01-200) in pediatric surgical…
- Conditions
- Indications for Laparoscopic Thoracic and Abdominal Surgery in Children, Congenital or Acquired Surgical Conditions Requiring Minimally Invasive Surgery in Children, Pyeloplasty, Ureteral Reimplantation
- Trial name
- NCT07530133
- Testing
- Thoracic and Abdominal Endoscopic Surgery System
- Where
- 3 sites in China
- Volunteers
- 64 people
- Sponsor
- Hangzhou Kangji Weijing Medical Robotics Co., Ltd.
Cerebral Palsy, Hemiplegia
Functional Benefits of Multisite Upper Limb Surgery in Children With Unilateral Cerebral Palsy (RETRO-CHIRc)
This retrospective study evaluates the functional impact of individualized multisite neuro-orthopedic upper limb surgery in children with unilateral cerebral palsy (hemiplegic CP).
- Trial name
- RETRO-CHIRc (NCT07891078)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Distal Radius Fractures
Impact of Early ADL Education on Outcomes Post DRF ORIF
This study is a randomized controlled trial (RCT). This RCT which will study the effect of performing daily activities early after a distal radius fracture being treated with surgical intervention of open reduction and internal…
- Trial name
- NCT06251206
- Testing
- ADL/Postoperative Instruction, Postoperative Instruction
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- George Washington University
Heart Diseases, Heart Diseases, Ischemic
Upper Extremity Elevation and Lungfunction After Open Heart Surgery
The purpose of this study is to assess if arm elevation, with or without simultaneous deep breathing, affects oxygen saturation and lung function on patients two to four days after open heart surgery.
- Conditions
- Heart Diseases, Heart Diseases, Ischemic, Heart Disease, Valvular
- Trial name
- NCT05278819
- Testing
- upper extremity elevation, upper extremity elevation with deep breathing
- Where
- Sweden
- Volunteers
- 22 people
- Sponsor
- Michael Reinhart
Cervical Cancer, Radical Surgery
A Single-arm, Multicenter, Phase II Clinical Study of Camrelizumab Combined With Famitinib in Adjuvant Therapy After Radical Resection of Cervical Cancer
This study is a single-arm, open-label, multicenter, exploratory clinical trial aimed at observing and evaluating the efficacy and safety of camrelizumab combined with famitinib in the adjuvant treatment of cervical cancer…
- Conditions
- Cervical Cancer, Radical Surgery, Adjuvant Therapy
- Trial name
- NCT07466901
- Testing
- Camrelizumab, famotinib
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jin LI
Chronic Limb-Threatening Ischemia, Surgery-Complications
Use of CPETarm for Risk Stratification of Patients With CLTI
This is a prospective cohort study of patients undergoing surgery for chronic limb threatening ischaemia. Prior to surgery, patients will undergo CardioPulmonary Exercise testing (CPET) using an arm ergometer.
- Trial name
- NCT06404229
- Testing
- CardioPulmonary Exercise Testing
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University of Manchester
Carpal Tunnel Syndrome
Ultrasound-Guided Curved Needle Thread Carpal Tunnel Release: Efficacy and Safety of a Single-Center, Single-Arm Clinical Trial
Carpal tunnel syndrome is a set of symptoms and signs caused by compression of the median nerve within the carpal tunnel. The prevalence in the general population is about 3.72%, with a rising trend, making it the most common…
- Trial name
- NCT06440070
- Testing
- Loop Carpal Tunnel Release
- Where
- China
- Volunteers
- 69 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Biliary Tract Carcinoma
SBRT Sequential Surufatinib Combined With Immunotherapy for Biliary Tract Carcinoma
This is a single-arm, open, single-center Phase II clinical study to observe and evaluate the efficacy and safety of SBRT sequential surufatinib combined with immunotherapy in patients with locally unresectable or recurrent…
- Trial name
- NCT06199882
- Testing
- SBRT Sequential Surufatinib Combined With Immunotherapy
- Where
- China
- Volunteers
- 34 people
- Sponsor
- Zhejiang Cancer Hospital
Anterior Cruciate Ligament Tear
A Comparison of ACL Repair With BEAR Device vs. Autograft Patellar Tendon ACL Reconstruction
This study is designed to evaluate bridge-enhanced ACL restoration (BEAR), a new surgical technique for repairing knees injured by a tear of the anterior cruciate ligament (ACL) that promotes reattachment and healing of the ACL…
- Trial name
- BEAR-MOON (NCT03776162)
- Testing
- ACL Reconstruction (Bone Patellar Tendon Bone Graft), Bridge Enhanced ACL Restoration (BEAR)
- Where
- 6 sites in United States
- Volunteers
- 150 people
- Sponsor
- The Cleveland Clinic
Cervical Spinal Cord Injury, Tetraplegia
Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI
Purpose: The objective of this study is to assess a newly created decision support intervention (DSI) or decision aid (DA) for people with spinal cord injury (SCI) to learn about and consider upper extremity reconstructive…
- Trial name
- NCT04995796
- Testing
- Surveys for Research Purposes
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Pterygium of the Conjunctiva and Cornea
Conjunctival Transpositional Surgery for Primary Pterygium
This prospective single-arm interventional study evaluates the recurrence rate and functional outcomes following conjunctival transpositional pterygium surgery without bare sclera formation.
- Trial name
- NCT07343011
- Testing
- Conjunctival Transpositional Pterygium Surgery
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Zahedan University of Medical Sciences
Hemorrhage
Study to Evaluate the Safety and Efficacy of HLBLS-200 in Patients Requiring Hemostatic Technique
This is a prospective, open-label, exploratory clinical trial designed to investigate the safety and efficacy of HLBLS-200 (an investigational hemostatic agent). The study will recruit approximately 8 subjects.
- Trial name
- NCT03957356
- Testing
- HLBLS-200
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- HLB Cell Co., Ltd.
Gastric Cancer
Safety and Efficacy of Sintilimab in Combination With Chemoradiothrapy Followed by D2 Surgical Resection in Patients With Advanced Gastric Cancer With Retroperitoneal Lymph Node Metastasis
Gastric cancer with retroperitoneal lymph node metastasis was considered as unresectable, to improve these patients' prognosis, we designed systematic conversion therapy including immunotherapy and chemoradiotherapy.
- Trial name
- NCT05002686
- Testing
- Sintilimab, Albumin-Paclitaxel, Capecitabine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ruijin Hospital
Supraclavicular Brachial Plexus Block
Th Effects of a Drug Dexmedotemidine in Regional Anesthesia in Participants Undergoing Upper Limb Surgeries
In this study, we will assess the effect of combined Dexmedetomidine and Bupivacaine analgesia on the onset and duration of anesthesia in supraclavicular plexus block compared to Bupivacaine alone.
- Trial name
- NCT04981951
- Testing
- Dexmedetomidine
- Where
- Palestinian Territories
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zaher Nazzal
Blood Loss, Surgical
Study to Investigate the Effect of Aprotinin of Transfusion Requirements in Patients Undergoing Surgical Procedures for Lung or Esophageal Cancer
Study to Investigate the Effect of Aprotinin of Transfusion Requirements in Patients Undergoing Surgical Procedures for Lung or Esophageal Cancer.
- Trial name
- NCT00306137
- Testing
- Trasylol (Aprotinin, BAYA0128)
- Where
- 21 sites in United States, Australia and 8 more
- Volunteers
- 104 people
- Sponsor
- Bayer
Upper Extremity Arterial Surgery
Long Term Patency Following Arterial Repair
Injury to the blood vessels of the extremities, and more specifically the arteries, can result from fractures and severe crush injuries. It occurs in about 3% of the general population.
- Trial name
- NCT02228057
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh
Virtual Reality, Upper Extremity Problem
Virtual Reality in Wide-Awake Hand Surgery
The vast majority of hand surgery performed at the Royal London Hospital is carried out with patients wide-awake. This is either using local or regional (brachial block) anaesthesia.
- Trial name
- VR-WAHS (NCT06817057)
- Testing
- Virtual Reality headset + headphones
- Sponsor
- Barts & The London NHS Trust
Acute Major Bleeding, Reversal of Coagulopathy
Study of a Prothrombin Complex Concentrate for Rapid Reversal of Coagulopathy Induced by Vitamin K Antagonists in Japanese Subjects
The purpose of this study is to evaluate efficacy and safety of a Prothrombin Complex Concentrate (PCC), BE1116. BE1116 will be used for the rapid reversal of coagulopathy induced by vitamin K antagonists in Japanese subjects who…
- Trial name
- NCT02281201
- Testing
- BE1116 (Prothrombin Complex Concentrate)
- Where
- 11 sites in Japan
- Volunteers
- 11 people
- Sponsor
- CSL Behring
Nerve Block, Neuromuscular Blockade
Dosage of Mepivacaine in Ultrasound Axillary Block
The use of ultrasonography as an adjunct to regional anesthesia has significantly increased in recent years. Brachial plexus blockade by an axillary approach is amenable to the use of ultrasound guidance.
- Conditions
- Nerve Block, Neuromuscular Blockade, Anesthesia
- Trial name
- NCT01485653
- Testing
- Mepivacaine
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Wayne State University