Clinical trials: Upper Limb Surgery
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Breast Carcinoma
Determining Quality of Life in Breast Cancer Patient After Completing Radiation,Chemotherapy,Surgery or Combination
Rationale: Determining quality of life in breast cancer patient after completing chemotherapy or radiation therapy or surgical procedures or any combination therapy.
- Trial name
- NCT00712621
- Testing
- Counseling, Written materials
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- American Scitech International
Cervical Cancer
The Efficacy of Salvage Surgery in Patients With Residual Tumor After Concurrent Chemoradiation for Locally Advanced Cervical Cancer.
This is a single-center single-arm study. The main purpose of this study is to study the efficacy of surgical treatment for patients with locally advanced cervical cancer (FIGO IB3, IIA2-IVA) who still have residual tumor after…
- Trial name
- NCT05749887
- Testing
- salvage surgery
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Chongqing University Cancer Hospital
Distal Humerus Fracture
Retrospective Analysis on Distal Humerus Fractures
The purpose of this study is to evaluate preoperative objective measurements for distal humerus ORIF patients and operative objective measurements to determine if there is any effect to postoperative outcomes.
- Trial name
- (DHFx) (NCT03637621)
- Testing
- ORIF
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Orthopaedic Research & Innovation Foundation
Contusions, Incision
Dermal Wound Closure Using Silkam®
Assessment of performance of Silkam® suture material for skin closure. A prospective, single center, single arm, observational study in daily practice.
- Conditions
- Contusions, Incision, Laceration
- Trial name
- DERMASILK (NCT05225714)
- Where
- Spain
- Volunteers
- 161 people
- Sponsor
- Aesculap AG
Hand Injury, Wrist Injury
Comparing Two Injection Sites of Local Anesthetic for Hand Surgery
The purpose of this study is to compare two different injection sites for local anesthesia in patients having hand surgery. The hypothesis is that subjects receiving injections around the three nerves of the forearm will provide…
- Conditions
- Hand Injury, Wrist Injury, Finger Injury
- Trial name
- NCT02112006
- Testing
- 0.5% bupivacaine injected in the forearm, 20-30ml of 0.5% bupivacaine.
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Non-Small Cell Lung Cancer (Stage III)
Integrating Surgery and Radiotherapy Following Tislelizumab-based Conversion Therapy in N3-Stage III NSCLC
This is a prospective, open, multicenter, Phase II single-arm clinical study. In subjects with an initial stage of stage III-N3 non-small cell lung cancer (NSCLC) that was negative for sensitive gene mutations and had not…
- Trial name
- NCT06908733
- Testing
- 3-4 cycles of Tislelizumab combined with platinum-based chemotherapy, evaluated by MDT and assigned to treatment strategies based on eligibility and patient preference.
- Volunteers
- 30 people
- Sponsor
- Liaoning Cancer Hospital & Institute
Epithelial Ovarian Cancer, Sentinel Lymph Node Detection
The Application of Sentinel Lymph Node Mapping Technique in the Surgery of Early Epithelial Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to evaluate the feasibility, sensitivity, and specificity of sentinel lymph node (SLN) mapping technology in the population with early epithelial ovarian…
- Trial name
- NCT06673511
- Testing
- Lymph node visualization, No visualization of lymph nodes
- Volunteers
- 246 people
- Sponsor
- Anhui Provincial Hospital
Uterine Fibroids (UF), Menstrual Disorders
Hugo™ Robotic-Assisted Surgery (RAS) System in Gynecological Subjects (Embrace Gynecology)
The purpose of this research is to evaluate the safety and performance of the investigational Medtronic Hugo™ Robotic Assisted Surgery (RAS) system when used during hysterectomy procedures, including patients being treated for…
- Conditions
- Uterine Fibroids (UF), Menstrual Disorders, Adenomyosis of Uterus, Endometriosis
- Trial name
- Embrace Gyn (NCT07120945)
- Testing
- Robotic Assisted-Surgery (RAS) Hysterectomy
- Where
- 5 sites in United States
- Volunteers
- 70 people
- Sponsor
- Medtronic - MITG
Wrist Fracture
Axillary Block in Association With Analgesic Truncal Blocks at the Elbow for Wrist Surgery.
Fractures of the forearm bones that occur around the wrist are common in the elderly. Standard anesthesia for its surgical treatment is regional anesthesia (RA): supraclavicular block, infraclavicular block or axillary block…
- Trial name
- BAXASSO (NCT04046744)
- Testing
- Axillary brachial plexus block with a long-acting local anesthetic, Axillary brachial plexus block with a short-acting local anesthetic + Analgesic block at the elbow with a long-acting local anesthetic, Ropivacaine
- Where
- 7 sites in France
- Volunteers
- 150 people
- Sponsor
- CMC Ambroise Paré
Orthopedic Disorder, Anxiety
Brachial Plexus Block vs. General Anesthesia for Anesthesia Anxiety Before Orthopedic Upper Extremity Surgery
Surgical procedures and anesthesia applications are situations in which people do not feel safe due to the current vital risks. Anxiety is a natural reaction that occurs in such situations, it manifests itself with worry and…
- Conditions
- Orthopedic Disorder, Anxiety, Upper Extremity Injury, Surgery
- Trial name
- NCT05476198
- Testing
- Brachial plexus block, General anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Opioid Use, Post-operative Pain
Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries
The purpose of this prospective cohort study is to evaluate the opiate prescribing patterns post open reduction and internal fixation (ORIF) of wrist and ankle fractures at the Ottawa Hospital.
- Conditions
- Opioid Use, Post-operative Pain, Prescription Opioid Abuse, Fracture, Ankle
- Trial name
- NCT05322564
- Testing
- Standardized opiate prescription
- Volunteers
- 100 people
- Sponsor
- The Ottawa Hospital
Patient Requiring Scheduled Conventional Orthopedic Surgical Intervention of the Upper or Lower Limb
Effectiveness of Energy Resonance by Skin Stimulation in the Management of Anxious Patients Who Require Scheduled Orthopaedic Surgery
The need for a surgical procedure may cause a patient to experience reactive anxiety. This reaction is appropriate if it is of low to moderate intensity.
- Trial name
- ERESCAO (NCT03773198)
- Testing
- Energy Resonance through Cutaneous Stimulation, questionnaires
- Where
- France
- Volunteers
- 86 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Unresectable Cholangiocarcinoma, Advanced/Metastatic Cholangiocarcinoma
A Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced/Metastatic or Surgically Unresectable Cholangiocarcinoma With FGFR2 Fusion or Rearrangements After at Least 1 Prior Line of Systemic Therapy
The purpose of this study is to confirm the efficacy and safety of pemigatinib in participants with advanced/metastatic or surgically unresectable cholangiocarcinoma with FGFR2 fusion or rearrangements after at least 1 prior line…
- Trial name
- FIGHT-214 (NCT07862998)
- Testing
- Pemigatinib
- Volunteers
- 72 people
- Sponsor
- Incyte Corporation
Breast Cancer
A Nationwide Multicenter, Single-arm, Retrospective Study of Delayed Endoscopic DTI-BR After Simple Mastectomy
This study is a nationwide multicenter, single-arm, retrospective study. The study aims to conduct a detailed analysis of operation-related parameters, aesthetic outcomes (e.g., BREAST-Q scores and Harris scores), and safety…
- Trial name
- DEDTI-BR (NCT07257003)
- Testing
- delayed endoscopic direct-to-implant breast reconstruction via axillary approach after simple mastectomy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Du Zhenggui
Postoperative Pain, Wrist Fracture
Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Distal radial fracture reparations by volar plating are often managed under regional anaesthesia, but are associated with severe pain when the block ends.
- Trial name
- BNINF (NCT02693288)
- Testing
- Local infiltration anesthesia
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Regional Anesthesia, Interscalene Blocks
Comparative Impacts of Two Anesthesia Methods on Peripheral Tissue Oxygenation in the Upper Limb
This study will aim to compare the effects of two different anesthesia techniques-general anesthesia (GA) and interscalene brachial plexus block (ISB)-on forearm tissue oxygenation in patients undergoing shoulder surgery.
- Conditions
- Regional Anesthesia, Interscalene Blocks, Shoulder Surgery, Perfusion Index
- Trial name
- NCT07449611
- Testing
- General Aneasthesia, Interscalene block
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sakarya University
Mammoplasty Patient
Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy
This phase II trial studies how well an imaging technique called perforator phase contrast angiography (pPCA) works in developing surgery plans for patients with breast cancer undergoing breast reconstruction after breast removal…
- Trial name
- NCT04063410
- Testing
- Angiography, MRI-Based Angiogram, Quality-of-Life Assessment
- Where
- United States
- Sponsor
- University of Cincinnati
Perfusion Index, Upper Extremity Surgery
Comparison of 90° and 120° Arm Positions in Costoclavicular Block
The costoclavicular approach of the infraclavicular brachial plexus block is widely used for upper extremity surgeries due to its reliable anatomy and high success rates.
- Conditions
- Perfusion Index, Upper Extremity Surgery, Brachial Plexus Block, Regional Anaesthesia
- Trial name
- COSTO-RCT (NCT07586670)
- Testing
- Costoclavicular Brachial Plexus Block
- Volunteers
- 106 people
- Sponsor
- Ankara Etlik City Hospital
Melanoma (Skin), Sarcoma
Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Infusing chemotherapy to the tumor area only may kill more tumor cells and cause less damage to healthy…
- Trial name
- NCT00004250
- Testing
- dactinomycin, isolated limb perfusion, melphalan
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Memorial Sloan Kettering Cancer Center