Clinical trials: Upper Resp Tract Infection
Healthy
The Effects of Manual Lymphatic Drainage on the Autonomic Nerve System
Forty healthy women who met the inclusion criteria were included in the study. In the single-blind randomized controlled study, the participants were divided into 3 groups manual lymphatic drainage(MLD), sham MLD, and control…
- Trial name
- NCT05809726
- Testing
- Manual lymph drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Cold-water Immersion, High Heat Sauna
Thermodynamic Exposure and Sleep in Military Cadets
This pilot study investigates the effects of cold-water immersion, traditional sauna use, and their combination on sleep architecture and psychological health in military cadets.
- Conditions
- Cold-water Immersion, High Heat Sauna, Combination of Cold-water Immersion and High Heat Sauna
- Trial name
- NCT07201935
- Testing
- Cold Water Immersion, High Heat Sauna
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Hemorrhage, Platelets; Defect
Extended Cold Stored Apheresis Platelets in Cardiac Surgery Patients
This trial is being performed to evaluate the feasibility of the study protocol and to test the efficacy and safety of platelets stored at cold conditions (1-6°C) in 100% plasma for 10-14 days (CSP) in cardiac surgery patients…
- Conditions
- Hemorrhage, Platelets; Defect, Bleeding, Surgical Blood Loss
- Trial name
- CHASE (NCT05220787)
- Testing
- Cold stored platelets in 100% plasma stored for 10-14 days, Room temperature stored platelets in 100% plasma stored for up to 7 days
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Moritz Stolla, MD
Acute Upper Respiratory Tract Infections
Trial of Post-Dated Delayed Antibiotic Prescriptions
Delayed prescriptions have been shown to lower antibiotic use for upper respiratory tract infections (which are mostly viral). This trial will test the hypothesis that if the clinician post-dates the delayed prescription by 2…
- Trial name
- NCT02732847
- Testing
- A delayed prescription dated 2 days after clinical office visit, Usual Dated
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- Memorial University of Newfoundland
Respiratory Tract Diseases
Study of Echinaforce Junior Tablets in Children With Acute Colds
This study aims to investigate safety and efficacy of Echinaforce Junior tablets in two dosages of 3 x 1 and 5 x 1 tablets per day in children 4 - 12 years old with acute colds.
- Trial name
- NCT02198391
- Where
- Switzerland
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- A. Vogel AG
Cardiovascular System
Acute Effects of Cold Exposure on Cardiovascular System
This is a randomized controlled human exposure crossover study. Investigators aim to assess the acute effects of low temperature exposure on cardiovascular system and the underlying mechanisms.
- Trial name
- NCT06652425
- Testing
- Low temperature (15°C) group, Moderate temperature (22°C) group
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fudan University
Influenza
Immunogenicity and Reactogenicity of GlaxoSmithKline (GSK) Biologicals' Quadrivalent Split Virion Influenza Vaccine Fluarix Tetra (2015 Season Southern Hemisphere) in Adults 18 Years of Age and Above
The purpose of this study is to evaluate the safety and immunogenicity of GSK Biologicals' Quadrivalent Split Virion Influenza Vaccine Fluarix Tetra (2015 Southern hemisphere) in adults (18 to 60 years of age) and in the elderly…
- Trial name
- NCT02369341
- Testing
- Fluarix Tetra
- Where
- 2 sites in Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Acne Vulgaris
Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study
Acne vulgaris is a common, chronic inflammatory skin disease with complex pathogenesis and limited therapeutic options, especially for moderate-to-severe cases.
- Trial name
- NCT07056673
- Testing
- Active CAP therapy, standard care based on the JAAD acne guidelines
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Shenyang Medical College
Common Cold
The Effect of Paracetamol, Pseudoephedrine Hydrochloride, Dextromethorphan Hydrobromide and Chlorpheniramine Maleate Tablets Compared to Placebo in Subjects Suffering From the Common Cold or Influenza.
This phase IV multi-centre, randomised, double-blind, placebo-controlled, parallel-group, single-dose study will assess the efficacy and tolerability of the active tablets versus placebo in participants suffering from cold and…
- Trial name
- NCT02246166
- Testing
- Test tablet
- Where
- 2 sites in China
- Volunteers
- 53 people
- Sponsor
- GlaxoSmithKline
COVID-19
The Efficacy, Safety and Immunogenicity Study of Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19
This is a randomized, double-blinded, placebo controlled phase III clinical trial to evaluate the efficacy, safety and immunogenicity of SARS-CoV-2 Vaccine, Inactivated (Vero Cell) in adults aged 18 years and above after 2-dose…
- Trial name
- NCT04659239
- Testing
- Inactivated SARS-CoV-2 Vaccine (Vero cell)
- Where
- 2 sites in Brazil, Malaysia
- Volunteers
- 34,020 people, healthy volunteers welcome
- Sponsor
- Chinese Academy of Medical Sciences
Particularly Partial-body Cryostimulation
Effect of Cryostimulation on Selected Motor Skills in Soccer Players
A randomized study was conducted during two training periods. The first stage of a 5-day cryostimulation procedure took place in November 2022, during the training period after the end of the league season.
- Trial name
- NCT06812819
- Testing
- Cryostimulation is a form of cooling the body using low temperatures without causing tissue damage. The stimulus effect is achieved at temperatures below - 110⁰C, in a short time of 1-3 minutes. The p
- Where
- Poland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Obesity
Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures
This study will examine how body metabolism adjusts to small changes in environmental temperature and how it may be related to weight loss.
- Trial name
- NCT00521729
- Testing
- Exposure to Cold Temperature
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Subdural Hematoma, Subdural Hematoma
Non-Thermal Plasma to Reduce Recurrence in Chronic Subdural Hematoma
The goal of this randomized controlled trial is to evaluate whether the adjuvant application of non-thermal plasma (NTP) during standard surgical drainage of chronic subdural hematoma (cSDH) can reduce the recurrence rate at 6…
- Conditions
- Chronic Subdural Hematoma, Subdural Hematoma, Recurrence, Postoperative Complications
- Trial name
- NCT07656818
- Testing
- Standard Surgery Protocol, Non-Thermal Plasma
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Benjamín Gonzalo Rodríguez Méndez
Residual Disease
R0 Resection Rate Between CSP, cEMR and hEMR for 1-2 cm Colorectal SSLs
Colorectal cancer is the most prevalent cancer and the third cancer related death in Taiwan. Adenoma is a precancerous lesion of colorectal cancer.
- Trial name
- NCT05117879
- Testing
- Cold snaring polypectomy/ Cold EMR/Hot EMR
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Taiwan University Hospital
Cold Therapy
Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?
The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction.
- Trial name
- NCT07370870
- Testing
- Cold Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Coronary Artery Disease
Year-round Health Enhancing Exercise and Coronary Artery Disease
A cold season involves higher cardiovascular morbidity and mortality. Several epidemiologic studies have implicated that persons with a cardiac disease, such as coronary artery disease (CAD) may be at higher risk for these…
- Trial name
- NCT02855905
- Testing
- Exercise/Rest and cold/neutral temperature
- Where
- Finland
- Volunteers
- 21 people
- Sponsor
- University of Oulu
Common Cold, Healthy
Efficacy Study of A Lotion to Prevent Common Colds
The purpose of this of this study is to determine if 3804-250A can prevent the common cold caused by the rhinovirus when applied to the hands.
- Trial name
- NCT00993759
- Testing
- 3804-250A
- Where
- United States
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- The Dial Corporation
Analgesic Effects of Music
The Sedative Effects of Music Listening on Pain During Cold Pressor Test
This study aims to understand whether listening to music can reduce pain and anxiety caused by a cold-temperature stimulus in healthy young adults (n = 30).
- Trial name
- ESEMP (NCT07515196)
- Testing
- Phase 1 - Silence (Baseline), Phase 2 - Happy Mode with Measured Rhythm, Phase 3 - Sad Mode with Measured Rhythm
- Where
- Lebanon
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Rawane El Dimachki
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
URTI - Viral Upper Respiratory Tract Infection
A Study to Assess the Effect Probiotic Supplement on Immune Health in Teachers Prone to Upper Respiratory Tract Infection
The present study is a randomized, placebo-controlled, double-blind, parallel-group clinical studydesigned to assess the effects of IP on immune health in teachers prone to URTI.
- Trial name
- NCT07033754
- Testing
- Propionibacterium freudenreichii P.UF1, Microcrystalline cellulose, calciumcarbonate, Mg Stearate, Sylysia
- Where
- 6 sites in India
- Volunteers
- 100 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.