Clinical trials: Ureter Injury
Ureter Injury
Evaluation of Lumitrace for Visualizing Ureters During Abdominopelvic Surgeries
The goal of this clinical trial is to learn if Lumitrace and the KARL STORZ POWER LED BLUE System can be used for anatomic visualization of the ureters in participants undergoing laparoscopic abdominopelvic surgery.
- Trial name
- NCT07080008
- Testing
- Lumitrace, KARL STORZ POWER LED BLUE System
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Uterovaginal Prolapse, Ureteral Injury
Ureteral Patency After Uterosacral Ligaments Suspension
Uterosacral ligament suspension (USLS) is a commonly performed procedure used to correct prolapse of the vaginal apex. The procedure consists of approximating the vaginal apex to the uterosacral ligaments with a series of sutures…
- Conditions
- Uterovaginal Prolapse, Ureteral Injury, Surgery--Complications
- Trial name
- NCT05477043
- Testing
- Transabdominal ultrasound and cistoscopy
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Milano Bicocca
Ureter Injury
Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency in Pediatric Patients
This is an open-label, multicenter study to evaluate the safety, pharmacokinetics, and conspicuity of a weight-based Bludigo® dose (0.05 mL/kg rounded up (if necessary) to a minimum of 0.5 mL and not to exceed 2.5 mL) when used…
- Trial name
- NCT06448143
- Testing
- Indigotindisulfonate sodium 0.8% injection
- Volunteers
- 18 people
- Sponsor
- Prove pharm
Ureteral Injury
Investigating Oral Agents for Urine Staining to Facilitate Intraoperative Observation of Ureteral Jets
Recently, Indigo Carmine and Methylene Blue have been the standard agents to visualize ureteral jets during intraoperative cystoscopy.
- Trial name
- NCT03432572
- Testing
- Pyridium, Riboflavin, Thiamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Urolithiasis
Measurement of Resistance During UAS Insertion Procedure in RIRS
Retrograde intrarenal surgery (RIRS) has been considered as the first-line choice for the management of <20mm kidney stones. Insertion of a ureteral access sheath (UAS) before RIRS surgery is currently accepted as an effective…
- Trial name
- NCT03919227
- Testing
- empty bladder before inserting UAS, do not interfere with the filling degree of bladder
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guohua Zeng
Ureter Injury
Ureter Identification With IRDye 800BK
Phase 1/2a study, second in-man utilising IRDye800BK in ureteric identification using fluorescence throughout abdominal surgery. Study is open label, non-randomised prospective study.
- Trial name
- NCT03387410
- Testing
- Intravenous IRDye 800BK
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Oxford University Hospitals NHS Trust
Open, Laparoscopic
Open Versus Laparoscopic Dismembered Pyeloplasty Among Adult Patients With Primary Pelvi-Ureteric Junction Obstruction
To prospectively compare the perioperative, morphological and functional outcomes on short and medium term between laparoscopic (LP) and open pyeloplasty (OP) patients.
- Conditions
- Open, Laparoscopic, Dismembered Pyeloplasty, Primary Pelvi-Ureteric Junction
- Trial name
- NCT06572371
- Testing
- Laparoscopic pyeloplasty, Open pyeloplasty
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Tanta University
Ureteral Injury
Evaluation of Sodium Fluorescein Use During Intraoperative Cystoscopy After Total Laparoscopic Hysterectomy
The primary objective is to describe the safety and efficacy of intravenous sodium fluorescein to visualize ureteral efflux during intraoperative cystoscopy after total laparoscopic hysterectomy.
- Trial name
- NCT02971800
- Testing
- sodium fluorescein injection 10%
- Where
- Canada
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Children, Obstructive Uropathy
Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage
To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children
- Conditions
- Children, Obstructive Uropathy, Acute Renal Failure, Ureteric Stones
- Trial name
- NCT02055430
- Testing
- percutaneous nephrostomy insertion, bilateral double J ureteric stent, Definitive stone management
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Ureter Injury
IS-001 Injection in Patients Undergoing Robotic-Assisted Gynecological Surgery
This study evaluates the safety and efficacy of intravenous injection of IS-001 to aid in intraoperative ureter structure delineation.
- Trial name
- NCT05954767
- Testing
- IS-001
- Where
- 8 sites in United States
- Volunteers
- 189 people
- Sponsor
- Intuitive Surgical
Colorectal Cancer, Colorectal Surgery
Assessing the Feasibility of Using Methylene Blue in Identifying Ureters During Colorectal Surgery
This study will assess whether methylene blue fluorescence imaging can help surgeons identify the ureters during colorectal surgery.
- Conditions
- Colorectal Cancer, Colorectal Surgery, Ureteric Injury
- Trial name
- NCT07861815
- Testing
- Intravenous Methylene Blue, Methylene Blue Fluorescence Imaging System
- Volunteers
- 20 people
- Sponsor
- Chinese University of Hong Kong
Ureter Injury
Indigotindisulfonate Sodium Injection, USP as an Aid in the Determination of Ureteral Patency
This is a randomized, multicenter study to evaluate the efficacy and safety of two dose levels (2.5 mL and 5.0 mL) of Bludigo when used as an aid in the determination of ureteral patency.
- Trial name
- NCT06054880
- Testing
- Indigotindisulfonate sodium 0.8%, Saline injection 0.9%
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Prove pharm
Intraoperative Ureter Visualization, Abdominolpelvic Surgery
A Study to Find Out if ASP5354 Can Clearly Help Show the Ureter During Surgery
The ureter was the tube that carries urine from the kidneys to the bladder. It was difficult for surgeons to see the ureter during abdominal surgery. This could lead to injuring the ureter which, although rare, could be serious.
- Trial name
- NCT05754333
- Testing
- pudexacianinium chloride
- Where
- 6 sites in United States
- Volunteers
- 107 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Urinary Tract Infections, Ureteric Injury
Safety and Efficacy of Different Irrigation System in Retrograde Intrarenal Surgery
Urolithiasis is one of the most prevalent urological diseases affecting general population across the world. The available treatment modalities for renal stones are Shock wave lithotripsy (SWL), Percutaneous Nephrolithotomy…
- Conditions
- Urinary Tract Infections, Ureteric Injury, Sepsis
- Trial name
- RIRS (NCT05018546)
- Testing
- Irrigation force
- Where
- Nepal
- Volunteers
- 92 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Placenta Accreta Spectrum, Abnormal Placentation
Effect of Methylene Blue Bladder Instillation on Urinary Tract Injuries During Cesarean Hysterectomy for Placenta Accreta Spectrum
This prospective cohort study aims to evaluate whether preoperative bladder filling with methylene blue dye can reduce the incidence of urinary tract injuries during cesarean hysterectomy in patients diagnosed with placenta…
- Conditions
- Placenta Accreta Spectrum, Abnormal Placentation, Cesarean Hysterectomy, Urinary Tract Injury
- Trial name
- NCT07129135
- Testing
- The bladder was filled with 300 ml diluted methylene blue (in normal saline) via Foley's catheter
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Usama Ahmed Elsaeed Salem, MD
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Injury of Ureter During Surgery (Disorder)
Trial to Visualize the Ureters With Nizaracianine Triflutate in Adults Undergoing Abdominopelvic Surgery
The goal of this clinical trial is to determine if the drug Nizaracianine Triflutate can help surgeons see and avoid the ureters during abdominopelvic surgery.
- Trial name
- TRIPHASE (NCT06101745)
- Testing
- Nizaracianine Triflutate
- Where
- 10 sites in United States, Netherlands
- Volunteers
- 336 people
- Sponsor
- Curadel Surgical Innovations, Inc.
Urolithiasis, Ureteral Injury
Effect of Preoperative Alpha-blockers on Successful Insertion Ureteral Access Sheath and Reduce Ureteral Injury in Non-prestented Patients During RIRS. Assessment of Factors for Successful Ureteral Access Sheath Insertion.
The aim of the study is to evaluate the effect of preoperative taking alpha-blockers (tamsulosin or silodosin) on the success rate of ureteral access sheath (UAS) insertion and the degree of ureteral injury during RIRS in…
- Conditions
- Urolithiasis, Ureteral Injury, Ureteral Access Sheath, Retrograde Intrarenal Surgery
- Trial name
- NCT07202923
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- St. Luke's Clinical Hospital, Russia
Ureteral Injury
Intravenous Sodium Fluorescein Versus Oral Phenazopyridine for Ureteral Patency
To determine the safety profile of sodium fluorescein in women undergoing cystoscopy during gynecologic surgery. To determine if either oral phenazopyridine or sodium fluorescein result in shorter cystoscopy times.
- Trial name
- NCT02757417
- Testing
- sodium fluorescein, phenazopyridine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center