Clinical trials: Ureteral Diseases
Kidney Stone, Kidney Calculi
Comparison of Lithotripsy Urolithiasis Machines
A comparison on the outcomes of patients undergoing shockwave lithotripsy using the Storz machine versus the Dornier machine.
- Conditions
- Kidney Stone, Kidney Calculi, Ureteral Calculi, Ureterolithiasis
- Trial name
- CoLUM (NCT04069338)
- Testing
- Lithotripter
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- The Cleveland Clinic
Urolithiasis, Ureterolithiasis
US-Non Contrast Computed Tomography Real-time Fusion for Urinary Stones Follow up
Urolithiasis is a universal problem, a large part of patients will be affected by multiple stones throughout their lifetime, with estimated recurrence rates of 75% within 20 years.
- Trial name
- NCT02539004
- Testing
- Ultrasound study
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Rambam Health Care Campus
Ureteral Obstruction, Flank Pain
Mirabegron as Medical Expulsive Therapy (MET) for Ureteral Stones and Ureteral Stent Pain
The study will be a prospective randomized double-blind placebo-controlled trial of mirabegron for medical expulsive therapy (MET) in patients with a CT (Computed Tomography) scan-proven ureteral stone between 4 to 10 mm…
- Trial name
- NCT02744430
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Baylor College of Medicine
Bladder Cancer
A Study of Surgical Techniques During Cystectomy
The purpose of this study is to look at two standard surgical techniques used during a radical cystectomy and see whether they influence outcomes such as length of stay in the hospital and infections after surgery.
- Trial name
- NCT06703476
- Testing
- Stent placement, Alvimopan
- Where
- 7 sites in United States
- Volunteers
- 530 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bladder Cancer, Ureter Cancer
Study of Genexol-PM in Patients With Advanced Urothelial Cancer Previously Treated With Gemcitabine and Platinum
Taxane-based chemotherapy is currently one of the most commonly used regimen for salvage chemotherapy in advanced urothelial carcinoma.
- Trial name
- NCT01426126
- Testing
- Genexol PM
- Where
- South Korea
- Volunteers
- 37 people
- Sponsor
- Asan Medical Center
Ureteral Stent-Related Symptom
Ureteral Stent Related Lower Urinary Tract Symptoms- A Comparative Study
Pigtails are inserted to relieve of pelviureteral system independent of the underlying cause. Pain, Lower Urinary Tract Symptoms (LUTS), hematuria and fever can be some of the early complications after their insertion..More than…
- Trial name
- NCT05598710
- Testing
- Pigtail Insertion
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- National and Kapodistrian University of Athens
Urinary Stones
Management of Fragments During Ureteroscopy
The purpose of this study is to study the outcome of patients after ureteroscopy in which all fragments remaining after holmium laser lithotripsy were retrieved compared to those where small, insignificant fragments were left for…
- Trial name
- NCT00637650
- Testing
- Ureteroscopy, Holmium Laser lithotripsy and active retrieval of fragments, Ureteroscopy, Holmium laser lithotripsy, no intent to retrieve any remaining fragment
- Where
- Israel
- Sponsor
- The Chaim Sheba Medical Center
Nephrolithiasis
Mirabegron And Ureteral Stent-related Pain (MAP) Trial
Ureteric stents are used often following ureteroscopy for prevention of obstruction from edema and/or stone fragments. Up to 75% of patients experience pain following stenting, as well as lower urinary tract symptoms (LUTS) such…
- Trial name
- MAP (NCT04286152)
- Testing
- Mirabegron 50 MG
- Where
- Canada
- Volunteers
- 142 people
- Sponsor
- Unity Health Toronto
Kidney Stone, Ureteral Calculi
Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy
The investigators will assess the use of Transcutaneous Neurostimulation (TENS), a pharmacological alternative, for treatment of ureteral stent pain post-ureteroscopy.
- Conditions
- Kidney Stone, Ureteral Calculi, Nephrolithiasis
- Trial name
- NCT05153629
- Testing
- TENS
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Stanford University
Uropathy, Kidney Transplantation
Feasibility of Magnetic-end Double-J Ureteral Stent Use in Children
Double-J ureteral stent (DJUS) is one of the most common devices used in urology. Ureteral stenting has a wide spectrum of indications that can be summarized in two words: obstruction and leakage.
- Trial name
- EFUJA (NCT04384939)
- Testing
- magnetic-end Double-J ureteral stent
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Calculi, Ureter Calculi
Naftopidil 75mg for Improving Clearance of Urinary Stones
The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.
- Trial name
- NCT02011737
- Testing
- naftopidil 75mg
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Flank Pain, Urinary Bladder, Overactive
Therapeutic Merit of Solifenacin in the Mitigation of Ureteral Stent-induced Pain and Lower Urinary Tract Symptoms
Most ureteral stent insertions follow ureteroscopy procedures for stone management. Stents are essentially designed to prevent the blockage of the ureter.
- Trial name
- NCT01381120
- Testing
- Solifenacin succinate treatment, Oxycodone and acetaminophen combination treatment
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Barrie Urology Associates
Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma
Immune Checkpoint Inhibitors With or Without Propranolol Hydrochloride In Patients With Urothelial Carcinoma
This research study is an open label study designed to evaluate the safety and translational correlative changes of the combination of propranolol hydrochloride and immune checkpoint inhibitors (ICI) in subjects with urothelial…
- Conditions
- Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma, Locally Advanced Urethral Urothelial Carcinoma
- Trial name
- NCT04848519
- Testing
- Pembrolizumab, Propranolol Hydrochloride, Nivolumab
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Emory University
Solid Tumor, Urethral Cancer
Bortezomib With Gemcitabine/Doxorubicin in Patients With Urothelial Cancer and Other Solid Tumors
The goal of this clinical research study is to find the highest tolerable dose of Gemzar® (gemcitabine) and Adriamycin® (doxorubicin) that can be given together with Velcade® (bortezomib) in patients with urothelial cancer or…
- Trial name
- NCT00479128
- Testing
- Bortezomib, Gemcitabine, Doxorubicin
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Bladder Cancer, Transitional Cell Bladder Cancer
A Phase II Study of AZD4877 (a Novel Anti-mitotic Agent) in Advanced Bladder Cancer
The purpose of this Phase II study is to determine if AZD4877, an experimental drug that is a novel anti-mitotic agent (Eg5 or Kinesin Spindle Protein inhibitor that interferes with tumor cell division leading to tumor growth)…
- Conditions
- Bladder Cancer, Transitional Cell Bladder Cancer, Urethra Cancer, Ureter Cancer
- Trial name
- NCT00661609
- Testing
- AZD4877
- Where
- 36 sites in United States, Canada and 3 more
- Volunteers
- 54 people
- Sponsor
- AstraZeneca
Kidney Stones
Study to Determine if There Are Specific Clinical Factors to Determine Stent Encrustation
Ureteral stent placement is one of the most common procedures performed within urology. The stents are generally placed for relief of obstruction or to prevent obstruction following a urological procedure.
- Trial name
- NCT00581178
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of California, Irvine
Ureteral Stones, Kidney Stones
Trial Comparing Relapse Rates Between Standard Ureteroscopic Removal Of Ureteral Stone And Standard Removal With Additional Ureterorenic Clearing Of Non-Symptomatic Stones In The Kidney
Patients with a ureteral or kidney stone that causes symptoms, like pain, frequently have small kidney stones that don't cause symptoms.
- Trial name
- NCT02210650
- Testing
- Symptomatic stone removal, Asymptomatic kidney stones and ureteral stone removed
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Indiana Kidney Stone Institute
Stones, Kidney, Stones Ureter
Flexible Ureteroscopy Versus Percutaneous Nephrolithotomy As Primary Treatment in Renal Stones 2-3 Cm
Flexible Ureteroscopy versus Percutaneous Nephrolithotomy as Primary Treatment in Renal Stones 2-3 Cm
- Conditions
- Stones, Kidney, Stones Ureter, Urolithiasis
- Trial name
- NCT06892626
- Testing
- RIRS, PNL
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Ureteral Stent-Related Symptoms, Ureteral Calculi
ComfiJ Versus Conventional Double-J Stent for Ureteral Stent Symptoms
This prospective multicenter randomized controlled trial will compare stent-related symptoms after placement of a ComfiJ ureteral stent versus a conventional double-J ureteral stent in adult patients undergoing unilateral…
- Conditions
- Ureteral Stent-Related Symptoms, Ureteral Calculi, Urolithiasis
- Trial name
- COMFIJ-DJS (NCT07627828)
- Testing
- ComfiJ Ureteral Stent, Conventional Double-J Ureteral Stent
- Where
- 3 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Vesicoureteral Reflux
DVD-Based Training Program in Self-Hypnosis for Children
The proposed study is designed to utilize a self-hypnosis DVD home-training program for parents to use with their children to teach self-hypnosis techniques for inducing relaxation and hypnotic analgesia.
- Trial name
- VCUG (NCT01483105)
- Testing
- DVD Self-Hypnosis Training Program
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University