Clinical trials: Ureteral Diseases
Ureteral Stent-Related Symptom
Dexamethasone for Ureteral STent Symptoms (DUSTS)
The purpose of this study to learn if high-dose dexamethasone, a type of long-acting steroid, works to decrease urinary symptoms and pain after ureteroscopy and stent placement for kidney stones.
- Trial name
- DUSTS (NCT06930690)
- Testing
- Dexamethasone Sodium Phosphate Injection 20 mg, Dexamethasone Sodium Phosphate Injection 4mg
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Methodist Hospital Research Institute
Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter
Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
The goal of this clinical trial is to learn whether the addition of spinal analgesia leads to superior recovery in patients undergoing robotic-assisted laparoscopic upper urinary tract surgery under general anesthesia.
- Conditions
- Other Specified Disorders of Kidney and Ureter, Benign Neoplasm of Ureter, Calculus of Kidney and Ureter, Ureter Cancer
- Trial name
- SMILe (NCT06349668)
- Testing
- spinal analgesia with morphine and bupivacaine, lidocaine infusion
- Where
- 3 sites in Sweden
- Volunteers
- 220 people
- Sponsor
- Hans Bahlmann
Ureterolithiasis, Nephrolithiasis
Prospective Comparison Between Different Laser Settings for Ureteral \ Kidney Stones Treatment During Ureteroscopy
A prospective study comparing different laser settings used for stone fragmentation during ureteroscopy
- Trial name
- NCT02279927
- Testing
- Ureteroscopy
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Carmel Medical Center
Renal Calculi
FANS vs Standard Ureteral Access Sheath in fURS
This is a prospective, interventional single blinded, randomized, single-center study designed to compare the efficacy of a ureteral access sheath with integrated suction (FANS) versus a standard ureteral access sheath (UAS) in…
- Trial name
- CLEAR-URS (NCT07463157)
- Testing
- Standard ureteral access sheath, Flexible and Navigable Suction (FANS) Ureteral Access Sheath
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- IRCCS San Raffaele
Kidney Stone, Ureteral Stone
The Performance of the SOLTIVE Laser System for Laser Lithotripsy in Kidney or Ureteral Stones
The purpose of this study is to collect real-world evidence on the performance of the SOLTIVE™ Premium SuperPulsed Laser System for laser lithotripsy in ureteroscopy, percutaneous nephrolithotomy (PCNL) and mini PCNL for kidney…
- Trial name
- NCT04556201
- Testing
- SOLTIVE™ Premium SuperPulsed Laser Fiber System
- Where
- 7 sites in United States, Denmark and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Olympus Corporation of the Americas
Urologic Diseases, Urological System Complication of Procedure
Migration of Intraureteral Stents Compared to Conventional Double-J Stents.
The purpose of this study is to determine if stents placed with only one loop in the kidney move more than stents placed with a loop in both the kidney and a bladder.
- Trial name
- NCT04763837
- Testing
- Intraureteral stent, Conventional Double-J stent
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Ureteral Obstruction
Functional MR Urography
The objective of functional Uro MR is to add to an initial morphological phase, based on T2 and T1 weighted MR sequences, a sequential contrast-enhanced acquisition allowing to obtain functional semi-quantitative parameters from…
- Trial name
- NCT00301470
- Testing
- MR urography
- Where
- 16 sites in France
- Volunteers
- 550 people
- Sponsor
- Central Hospital, Nancy, France
Vesicoureteral Reflux, Urinary Tract Infections
Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)
In this 2-year, multisite, randomized, placebo-controlled trial involving 607 children with vesicoureteral reflux that was diagnosed after a first or second febrile or symptomatic urinary tract infecton, we evaluated the efficacy…
- Trial name
- RIVUR (NCT00405704)
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- 19 sites in United States
- Volunteers
- 607 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Advanced Bladder Urothelial Carcinoma, Advanced Renal Pelvis Urothelial Carcinoma
Testing the Addition of the Anti-cancer Drug, Cabozantinib, to the Usual Immunotherapy Treatment, Avelumab, in Patients With Metastatic Urothelial Cancer, MAIN-CAV Study
This phase III trial compares the effect of adding cabozantinib to avelumab versus avelumab alone in treating patients with urothelial cancer that has spread from where it first started (primary site) to other places in the body…
- Conditions
- Advanced Bladder Urothelial Carcinoma, Advanced Renal Pelvis Urothelial Carcinoma, Advanced Ureter Urothelial Carcinoma, Advanced Urethral Urothelial Carcinoma
- Trial name
- NCT05092958
- Testing
- Avelumab, Biospecimen Collection, Bone Scan
- Where
- 275 sites in United States, Canada
- Volunteers
- 654 people
- Sponsor
- National Cancer Institute (NCI)
Kidney Calculi, Ureteral Calculi
Study of Ketorolac Versus Opioid for Pain After Endoscopy
A double blind randomized controlled trial designed to compare pain control and safety with ketorolac and oxycodone in the post-operative setting for patients undergoing ureteroscopy for treatment of urinary stones.
- Trial name
- SKOPE (NCT03888144)
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Nephrolithiasis, Kidney Stone
ClearPetra™ Vacuum-assisted Ureteral Access Sheath vs Traditional Approach
Ureteroscopy has been considered the best approach when treating renal stones smaller than 2 cm. This procedure is usually performed together with ureteral access sheaths, which helps protect the ureter mucosa and lowers…
- Trial name
- VA-UAS vs trad (NCT06547632)
- Testing
- ClearPetra Ureteral access sheath
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Kidney Cancer, Ureteral Cancer
Postoperative Telerounding: A Multi-Center Prospective Randomized Assessment of Patient Outcomes and Satisfaction.
Telerounding is the use of wireless remote video-confrencing to assess hospitalized patients. Physicians thus rely on all ususal data collected during bedside rounds with the exeption of a direct physical exam.
- Conditions
- Kidney Cancer, Ureteral Cancer, Prostate Cancer, Nephrolithiasis
- Trial name
- NCT00263107
- Testing
- telerounding versus bedside rounding
- Where
- 3 sites in United States
- Volunteers
- 270 people
- Sponsor
- University of California, Davis
Kidney Stones
Occlusion Balloon vs. 5FR Ureteral Catheter
Occlusion Balloon catheter provides the ability to occlude the exit of the kidney pelvis during percutaneous nephrolithotomy (PCNL) and potentially prevents the migration of stone fragments into the ureter.
- Trial name
- NCT06798753
- Testing
- Occlusion Balloon Catheter, 5FR Ureteral Catheter
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ureter Stone
Prospective Relationship Between the Rates of Spontaneous Passage of Distal Ureteral Stones and the Distal Lumen
Patients (female, male, or queer) with ureteral stones (smaller than 1 cm at the widest diameter of the stone) without pyonephrosis, urinary sepsis, or untraceable pain will be enrolled into the study.
- Trial name
- NCT05416502
- Testing
- Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Hiram's Healthcare and Education Company
Ureteral Calculi
Comparing Uretersocopy With Versus Without Use of Guide-wire in Treatment of Ureteral Stone
The purpose of this study is to compare ureteroscopy with and without use of safety guide-wire in treatment of ureteral stone
- Trial name
- NCT03726502
- Testing
- ureteroscopy with safety guide-wire, ureteroscopy alone, without safety guide-wire
- Where
- Iran
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Kidney Stones
Use of the PercSys MicroStent Device to Alleviate Ureteral Stone Symptoms and Hydronephrosis
Kidney stones cause severe pain. Patients with a stone lodged in the ureter (the tube that drains the bladder), require urgent treatment with a stent to relieve the blockage.
- Trial name
- NCT01637519
- Where
- 2 sites in Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Urolithiasis, Nephrolithiasis
Does Treatment With Alfuzosin Increase Success Rates of (SWL) Shock Wave Lithotripsy
In latest literature more evidence is available about the positive effect of alpha blocker on stone expulsion from the ureter. Patients benefit from less pain and shortening time to stone expulsion.
- Conditions
- Urolithiasis, Nephrolithiasis, Ureterolithiasis
- Trial name
- NCT00409227
- Testing
- Alpha blocker-alfuzosin
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Bacterial Colonization in Double J Ureteral Stent
Risk Factors for Bacterial Stent Colonization in Patients With a Double J Ureteral Stent
The goal of this prospective study is to identify the risk factors associated with bacterial colonization of DJS and report the common microorganisms isolated and drug susceptibility pattern.
- Trial name
- NCT06510790
- Testing
- Double J stent
- Where
- Nepal
- Volunteers
- 48 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Localized Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Bladder Urothelial Carcinoma
Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer
This phase III trial studies how well pembrolizumab works in treating patients with bladder cancer that has spread into the deep muscle of the bladder wall (muscle-invasive) or urothelial cancer that has spread from where it…
- Conditions
- Localized Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Bladder Urothelial Carcinoma, Locally Advanced Renal Pelvis and Ureter Urothelial Carcinoma, Locally Advanced Ureter Urothelial Carcinoma
- Trial name
- AMBASSADOR (NCT03244384)
- Testing
- Biospecimen Collection, Clinical Observation, Computed Tomography
- Where
- 914 sites in United States, Guam
- Volunteers
- 739 people
- Sponsor
- National Cancer Institute (NCI)
Renal Stone Disease, Renal Stones
Flexible Ureteroscopy With Novel Flexible Ureteral Access Sheath Versus Mini-Percutaneous Nephrolithotomy for Treatment of 2-3cm Lower Calyceal Renal Stones
The aim of the study is to compare the efficacy, safety, and patient outcomes of flexible ureteroscopy with a novel flexible ureteral access sheath and mini-percutaneous nephrolithotomy in the treatment of 2-3 cm lower calyceal…
- Conditions
- Renal Stone Disease, Renal Stones, Flexible Ureteroscopy, Mini Percutaneous Nephrolithotomy
- Trial name
- NCT07904676
- Testing
- Flexible Ureteroscopy with Novel Flexible Ureteral Access Sheath, Mini-Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University