Clinical trials: Ureteral Stones
Stone, Urinary
Silodosin vs Tamsulosin as MET
The spontaneous passage rate for ureteral stone less than 1cm causing acute ureteral obstruction is about 50%. Previous Cochrane review has concluded that alpha blocker is likely to increase stone passage rate, reduce time to…
- Trial name
- NCT05570084
- Testing
- Silodosin, Tamsulosin
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- Princess Margaret Hospital, Hong Kong
Ureteral Calculi
Risk Factors and Predictive Model for Inflammatory Polyps in Ureteral Stones
This is an observational studyincluding an internal retrospectivedevelopment cohort, an internalprospective temporal validation cohortand two external validation cohorts fromtwo independent external centers.
- Trial name
- UROLITH-POLYP (NCT07559721)
- Where
- China
- Volunteers
- 1,351 people
- Sponsor
- The First Hospital of Jilin University
Urolithiasis
Effect of Use of Ureteral Access Sheath on Levels of Netrin-1 in Patients Undergoing RIRS
In this study, it is aimed to evaluate whether use of a ureteral access sheath (UAS) during retrograde intrarenal surgery (RIRS) due to kidney stone has any effect on protecting the kidney functions by measuring blood and urine…
- Trial name
- NCT02533414
- Testing
- RIRS with UAS, RIRS without UAS
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Kidney Stone, Ureteral Calculi
Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy
The investigators will assess the use of Transcutaneous Neurostimulation (TENS), a pharmacological alternative, for treatment of ureteral stent pain post-ureteroscopy.
- Conditions
- Kidney Stone, Ureteral Calculi, Nephrolithiasis
- Trial name
- NCT05153629
- Testing
- TENS
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Stanford University
Ureteral Stones, Ureteroscopic Lithotripsy
Ureteroscope Caliber and Surgeon Stress
This study aims to compare the efficacy, success rates, and stone-free rates of endoscopic ureteral stone treatment performed using two different sizes of ureteroscopes.
- Trial name
- NCT06935500
- Testing
- endoscopic ureteric lithotripsy
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Aydin Adnan Menderes University
Urolithiasis, Nephrolithiasis
Effect of Furosemide on ESWL Outcomes for Renal and Ureteral Calculi
The minimally-invasive extracorporeal shockwave lithotripsy (ESWL) procedure is generally considered the best first-line treatment option for most adults and children with nephrolithiasis, especially when the calculi are smaller…
- Conditions
- Urolithiasis, Nephrolithiasis, Urinary Calculi, Ureterolithiasis
- Trial name
- NCT05270421
- Testing
- Furosemide 40 mg, Conventional Treatment
- Where
- Iran
- Volunteers
- 500 people
- Sponsor
- Shiraz University of Medical Sciences
Stone, Urinary, Stone, Kidney
Effect of Preop Stent Duration on SFR and Secondary Intervention in RIRS
This study aims to evaluate how placing a stent before surgery (preoperative stenting or passive dilation) affects the success rate of retrograde intrarenal surgery (RIRS), which is performed for kidney stones.
- Trial name
- NCT07052188
- Testing
- without any preoperative stenting, (DJ) stent placed with sedation and undergo RIRS within 2-4 weeks, Patients will have a DJ stent placed with sedation and undergo RIRS within 4-6 weeks.
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Bedreddin Kalyenci
Ureteric Stone
Ultraslow SWL Versus Slow SWL for Ureteric Stones With High Attenuation Value
Ultraslow full-power SWL versus slow power-ramping SWL in ureteric stones with high attenuation value
- Trial name
- ESWL (NCT03795545)
- Testing
- SWL
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Cairo University
Ureteral Calculi
Celecoxib (Celebrex) in the Management of Acute Renal Colic
The purpose of this trial is to quantify the amount Celebrex, a specific cyclooxygenase-2 (COX-2) inhibitor, when used for the management of acute renal colic for a ureteral stone will: reduce pain medication usage improve the…
- Trial name
- NCT00304317
- Testing
- celecoxib
- Where
- United States
- Sponsor
- University of Minnesota
Renal Stone Disease, Ureteral Stricture
Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients
This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025.
- Conditions
- Renal Stone Disease, Ureteral Stricture, Hydronephrosis, Urolithiasis
- Trial name
- NCT07767773
- Testing
- Ureteral access sheath-assisted RIRS, Sheathless RIRS
- Where
- Egypt
- Volunteers
- 1,200 people
- Sponsor
- Al-Azhar University
Ureteral Stone, Urolithiasis
Phosphodiesterase 5 Inhibitors (PDE5i) (Sildenafil) as Medical Expulsive Therapy in Distal Ureteral Stones
Urolithiasis is one of the most common urological diseases. The risk of urolithiasis is estimated to be between 5% and 12% all over the world with increased incidence in male rather than female (2:1) respectively .
- Trial name
- NCT02519153
- Testing
- Sildenafil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Ureteral Stenosis, Hydronephrosis
Efficacy and Safety of Allium Ureteral Stent for Treating Refractory Ureteral Stricture
To conduct a prospective, multi-center study to observe the long-term efficacy and safety of self expanding ureteral stent for treating participants with refractory ureteral stricture.
- Conditions
- Ureteral Stenosis, Hydronephrosis, Ureteral Stent Occlusion
- Trial name
- Allium (NCT05455307)
- Testing
- Allium ureteral stent
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- En Chu Kong Hospital
Renal Stone, Nephrolithiasis
Impact Ureteral Sheath Design During Ureteroscopy
The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available.
- Conditions
- Renal Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT03349099
- Testing
- Cook Flexor, Boston Scientific Navigator
- Volunteers
- 95 people
- Sponsor
- The Cleveland Clinic
Renal Stone, Ureteral Stone
Effectiveness of Holmium and Thulium Lasers With Ureteroscopy for Urinary Lithiasis
Holmium laser is the current gold standard for lithotripsy on urinary lithiasis, while Thulium is brand new. The latter has been released in July 2020 in Europe, and only in-vitro studies have been published.
- Trial name
- LiThuHol (NCT04871984)
- Testing
- Ureteroscopy for upper tract stone treatment with Holmium laser, Ureteroscopy for upper tract stone treatment with Thulium laser
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Urolithiasis
Measurement of Resistance During UAS Insertion Procedure in RIRS
Retrograde intrarenal surgery (RIRS) has been considered as the first-line choice for the management of <20mm kidney stones. Insertion of a ureteral access sheath (UAS) before RIRS surgery is currently accepted as an effective…
- Trial name
- NCT03919227
- Testing
- empty bladder before inserting UAS, do not interfere with the filling degree of bladder
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Guohua Zeng
Kidney Neoplasm, Kidney Stone
A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members
Approximately 30,000 new patients are introduced into dialysis and about 20,000 of them die every year in Japan. At present, about 300,000 patients are on dialysis and more than 10,000 patients are registered with the Japan Organ…
- Conditions
- Kidney Neoplasm, Kidney Stone, Ureteral Tumor, Ureteral Stricture
- Trial name
- NCT00994188
- Testing
- Restored Kidney Transplant Between Family Members
- Where
- 2 sites in Japan
- Volunteers
- 5 people
- Sponsor
- Tokushukai Medical Group
Renal Stone, Retrograde Intrarenal Surgery
Tamsulosin Assisted Ureteral Access Sheath Insertion
Aim is to study if 1 week of pre operative tamsulosin would enable easier insertion of ureteral access sheath in primary retrograde intrarenal surgery for renal stone disease
- Conditions
- Renal Stone, Retrograde Intrarenal Surgery, Urolithiasis
- Trial name
- NCT05197088
- Testing
- Tamsulosin
- Where
- Singapore
- Volunteers
- 110 people
- Sponsor
- Sengkang General Hospital
Urinary Tract Stone
Moses vs. Thulium Laser Study
The incidence of urinary tract stone disease is increasing. According to the National Health and Nutrition Examination Survey, as of 2012, 10.6% of men and 7.1% of women in the United States are affected by renal stone disease.
- Trial name
- NCT04963062
- Testing
- Holmium laser with Moses lasers, Holmium laser with thulium lasers
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Wisconsin, Madison
Ureteric Stone, Flexible Ureteroscopy
Flexible vs Semi-rigid URS
To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.
- Conditions
- Ureteric Stone, Flexible Ureteroscopy, Upper Urinary Tract Stones
- Trial name
- NCT07247617
- Testing
- Flexible URS, Semi-Rigid URS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Kidney Stones
Steerable vs Conventional FANS for <2cm Lower Pole Stone Treatment: SCULPT Trial
This multicenter, randomized, controlled superiority trial (the SCULPT trial) aims to compare the efficacy and safety of a novel steerable flexible and navigable suction ureteral access sheath (FANS) versus the conventional FANS…
- Trial name
- NCT06898216
- Testing
- Steerable FANS, Conventional FANS
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University