Clinical trials: Ureteral Stricture, active
Ureteral Stricture, Hydronephrosis
Application of the Sentire C1000 for Ureteral Stricture Repair
The purpose of this clinical study is to evaluate the safety and efficacy of the Sten® Laparoendoscopic Surgical System C1000 for benign ureteral reconstruction surgery.
- Trial name
- ROBUST-C1000 (NCT06983067)
- Testing
- Cornerstone C1000 Robotic Surgery System
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xuesong Li
Ureteral Stricture
Duration of Ureteral Rest Prior to Ureteral Reconstruction Surgery
Our objective is to assess the effect of duration of ureteral rest, defined as time from conversion of ureteral stent to percutaneous nephrostomy, on stricture length prior to ureteral reconstruction surgery.
- Trial name
- NCT06384079
- Testing
- Antegrade and retrograde pyelogram
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University
Ureteral Stenosis
An Investigation Into the Application of Preputial Grafts for the Reconstruction of Complex Ureteral Strictures
Complex ureteral stricture refers to a ureteral lumen stenosis lesion that cannot be directly treated with the traditional end-to-end anastomosis.
- Trial name
- PGU20240101 (NCT07408050)
- Testing
- Preputial graft ureteroplasty
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruibao chen
Ureteral Stenosis, Hydronephrosis
Efficacy and Safety of Allium Ureteral Stent for Treating Refractory Ureteral Stricture
To conduct a prospective, multi-center study to observe the long-term efficacy and safety of self expanding ureteral stent for treating participants with refractory ureteral stricture.
- Conditions
- Ureteral Stenosis, Hydronephrosis, Ureteral Stent Occlusion
- Trial name
- Allium (NCT05455307)
- Testing
- Allium ureteral stent
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- En Chu Kong Hospital
Ureter Stricture
Buccal Mucosal Graft Ureteroplasty for Treatment of Proximal Ureteric Strictures, A Clinical Case Series.
While short strictures and even long strictures in the distal or mid-section of the ureter can easily be repaired by end-to-end anastomosis or simple re-implantation as well as standard procedures, such as psoas bladder hitch…
- Trial name
- NCT07797829
- Testing
- Buccal mucosal graft ureteroplasty
- Volunteers
- 25 people
- Sponsor
- Mohamed Salah Abdul Mawgoud
Renal Stone Disease, Ureteral Stricture
Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients
This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025.
- Conditions
- Renal Stone Disease, Ureteral Stricture, Hydronephrosis, Urolithiasis
- Trial name
- NCT07767773
- Testing
- Ureteral access sheath-assisted RIRS, Sheathless RIRS
- Where
- Egypt
- Volunteers
- 1,200 people
- Sponsor
- Al-Azhar University
Ureteral Stricture, Dexmedetomidine
Dexmedetomidine-Esketamine Combination on Depression and Anxiety After Laparoscopic Ureteral Reconstruction
Anxiety and depressive symptoms are prevalent in patients undergoing surgical repair for ureteral stricture, driven by chronic pain, renal function concerns, and surgical uncertainty.
- Conditions
- Ureteral Stricture, Dexmedetomidine, Esketamine, Depressive Symptoms
- Trial name
- NCT07753772
- Testing
- Combined dexmedetomidine-esketamine administration
- Where
- China
- Volunteers
- 658 people
- Sponsor
- Peking University First Hospital
Ureteral Obstruction, Stricture Ureter
Use of SPY Fluorescent Angiography to Reduce Ureteroenteric Stricture Rate Following Urinary Diversion
Ureteroenteric anastomotic stricture is a well-known complication of urinary diversion which occurs in 4-25% of patients. Recent study has yielded that radiation is a significant risk factor for development of ureteroenteric…
- Trial name
- NCT05022199
- Testing
- SPY fluorescent angiography
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Ureteral Stricture, Ureteral Obstruction
An Integrated Multi-omics Study on the Molecular Mechanisms of Ureteral Stricture
The goal of this observational study is to investigate the systemic pathogenesis and identify potential diagnostic biomarkers in patients with ureteral stricture and healthy volunteers.
- Conditions
- Ureteral Stricture, Ureteral Obstruction, Microbiome, Metabolomics
- Trial name
- US-MOP (NCT07409870)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Ureteral Stricture
EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures
The main objective of this clinical investigation is to assess the safety and feasibility of the Optilume DCB for treatment of ureteric strictures.
- Trial name
- ENDURE1 (NCT07020520)
- Testing
- Optilume
- Where
- 7 sites in United States
- Volunteers
- 60 people
- Sponsor
- Urotronic Inc.
Hydronephrosis; Obstruction, Ureter, Renal Failure
Tandem Polyurethane Stents Compared to Single Silicone Stent for Malignant Ureteral Obstruction
Malignant ureteral obstruction (MUO) is an extrinsic ureteral obstruction caused by malignant diseases. This study aim to compare tandem 6 Fr Percuflex™ stents and single large-caliber 8Fr silicone stent in patients with MUO.
- Conditions
- Hydronephrosis; Obstruction, Ureter, Renal Failure, Malignancy, Ureter Obstruction
- Trial name
- TSTENT (NCT05992363)
- Testing
- ureteral stent\s insertion
- Where
- 2 sites in Israel
- Volunteers
- 106 people
- Sponsor
- Rabin Medical Center