Clinical trials: Ureterolithiasis, open to volunteers
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Ureteral Stent-Related Symptoms, Ureteral Calculi
ComfiJ Versus Conventional Double-J Stent for Ureteral Stent Symptoms
This prospective multicenter randomized controlled trial will compare stent-related symptoms after placement of a ComfiJ ureteral stent versus a conventional double-J ureteral stent in adult patients undergoing unilateral…
- Conditions
- Ureteral Stent-Related Symptoms, Ureteral Calculi, Urolithiasis
- Trial name
- COMFIJ-DJS (NCT07627828)
- Testing
- ComfiJ Ureteral Stent, Conventional Double-J Ureteral Stent
- Where
- 3 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Ureteral Stent-Related Symptoms, Ureteral Calculi
Melatonin and Solifenacin for Double-J Ureteral Stent Symptoms
Double-J ureteral stents are commonly inserted after ureteroscopy, but they may cause bothersome urinary symptoms, pain, sleep disturbance, and reduced quality of life.
- Conditions
- Ureteral Stent-Related Symptoms, Ureteral Calculi, Lower Urinary Tract Symptoms
- Trial name
- MEL-SOL-STENT (NCT07617922)
- Testing
- Solifenacin, Melatonin
- Where
- Egypt
- Volunteers
- 189 people
- Sponsor
- Beni-Suef University
Renal Calculi, Ureteral Calculi
Intraoperative Assessment of of Burst Wave Lithotripsy (BWL)
Burst Wave Lithotripsy (BWL) is a novel method of urinary stone fragmentation that uses multi-cycle bursts of low amplitude ultrasound to induce stone fracture.
- Trial name
- NCT03873259
- Testing
- Burst Wave Lithotripsy
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Washington
Ureteral Calculi
URSL Angle for Predicting Intraoperative Conversion
This international multicenter retrospective cohort study aims to externally validate the URSL Predictive Angle, a novel CT-derived morphometric parameter, as an imaging biomarker for predicting intraoperative conversion risk…
- Trial name
- URSL-PREDICT (NCT07561684)
- Volunteers
- 2,200 people
- Sponsor
- The First Hospital of Jilin University
Pediatric Urolithiasis, Distal Ureteral Stone
Intravesical Aminophylline to Facilitate Ureteroscopic Access in Children With Distal Ureteral Stones.
This study will evaluate whether intravesical aminophylline can facilitate semi-rigid ureteroscopic access in children with distal ureteral stones when the first gentle attempt to enter the ureter is unsuccessful.
- Conditions
- Pediatric Urolithiasis, Distal Ureteral Stone, Ureteral Calculi
- Trial name
- NCT07617896
- Testing
- Aminophylline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Ureter Calculi
The Effect of Acupuncture on Passing Ureteral Stones
Ureteral stones are a common condition, especially small and distal stones, and can cause renal colic pain. Medical expulsive therapy (MET) is widely used to facilitate stone passage.
- Trial name
- NCT07893431
- Testing
- medical expulsive therapy (tamsulosin), Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hitit University
Acute Calculous Anuria, Ureteral Calculi
Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria
Acute calculous anuria is a urological emergency caused by ureteral stone obstruction in a solitary functioning kidney or bilateral ureteral obstruction.
- Conditions
- Acute Calculous Anuria, Ureteral Calculi, Obstructive Uropathy, Acute Kidney Injury
- Trial name
- NCT07617948
- Testing
- Intravesical Aminophylline
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Beni-Suef University
Ureterolithiasis, Renal Calculi
Super-Pulsed Thulium Fiber Laser Versus Holmium:YAG Laser in Retrograde Intrarenal Surgery for Upper Ureteral and Renal Stones
The holmium laser is currently considered the gold standard for lithotripsy on urinary lithiasis, whereas the super-pulsed thulium fibre laser is a relatively new technology.
- Trial name
- NCT07012941
- Testing
- Superpulse Thulium Fiber laser (SPTFL) ureteroscopy for treatment of upper urinary tract stone or renal stone, Holmium: YAG laser ureteroscopy for treatment of upper urinary tract stone or renal stone
- Where
- China
- Volunteers
- 448 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Stone;Renal, Stone Ureter
Application of Traditional Chinese Medicine Five-Element Music Therapy Combined With Acupoint Patch Therapy Based on the "Holistic Mind-Body Treatment" Theory in Upper Urinary Tract Calculi Treated With Ureteroscopic Lithotripsy Under Local Anesthesia
This study aims to evaluate whether the combination of Traditional Chinese Medicine Five-Element Music Therapy and acupoint patch therapy can effectively reduce intraoperative pain and anxiety in patients undergoing ureteroscopic…
- Trial name
- NCT07607626
- Testing
- Traditional Chinese Medicine Acupoint Patch with Five-Element Music Therapy, Standard Local Anesthesia
- Volunteers
- 60 people
- Sponsor
- Li Fang
Stone Ureter
ESWL vs Flexible Uretroscopy in Management of Upper Ureteric Stones a Prospective Randomized Study
This comparison between ESWL and flexible ureteroscopy aims to explore the efficacy, safety, and outcomes of these treatments for upper ureteric stones under 15 mm, focusing on stone-free rates, procedural risks, recovery times…
- Trial name
- NCT06722703
- Testing
- shock wave lithotripsy, Flexible ureteroscope lithotripsy
- Volunteers
- 42 people
- Sponsor
- Assiut University
Urolithiasis, Ureterolithiasis
PRedictive Accuracy of Initial Stone Burden Evaluation.
This study is intended to be a prospective registry of patients undergoing any kind of stone treatment that have a pre-operative CT available.
- Conditions
- Urolithiasis, Ureterolithiasis, Nephrolithiasis
- Trial name
- PRAISE (NCT04746378)
- Testing
- Computed Tomography, CSD, Computed Tomography, SA, Computed Tomography, 3D
- Where
- Belgium
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Ghent
Ureteral Stenosis, Hydronephrosis
Efficacy and Safety of Allium Ureteral Stent for Treating Refractory Ureteral Stricture
To conduct a prospective, multi-center study to observe the long-term efficacy and safety of self expanding ureteral stent for treating participants with refractory ureteral stricture.
- Conditions
- Ureteral Stenosis, Hydronephrosis, Ureteral Stent Occlusion
- Trial name
- Allium (NCT05455307)
- Testing
- Allium ureteral stent
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- En Chu Kong Hospital
Ureteric Stone, Flexible Ureteroscopy
Flexible vs Semi-rigid URS
To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.
- Conditions
- Ureteric Stone, Flexible Ureteroscopy, Upper Urinary Tract Stones
- Trial name
- NCT07247617
- Testing
- Flexible URS, Semi-Rigid URS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Urinary Tract Stones, Urinary Stones
ESWL for Distal Ureteric Stone: Supine Versus Prone
Extracorporeal shockwave lithotripsy (ESWL) for urinary stone is common and widespread nowadays. Approximately 80% of urinary stones are treated by ESWL.
- Conditions
- Urinary Tract Stones, Urinary Stones, Urinary Calculi
- Trial name
- NCT02298465
- Testing
- Supine ESWL, Prone ESWL, Extracorporeal Shockwave Lithotripsy (ESWL)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Queen Mary Hospital, Hong Kong
Calculous Anuria, Upper Ureteral Stone
Initial Drainage Method and Flexible Ureteroscopy Outcomes in Calculous Anuria
Calculous anuria caused by obstructing upper ureteral stones in a solitary functioning kidney is a urological emergency requiring urgent decompression.
- Conditions
- Calculous Anuria, Upper Ureteral Stone, Obstructive Uropathy, Acute Kidney Injury
- Trial name
- NCT07627880
- Testing
- Initial JJ Ureteral Stent Drainage, Initial Percutaneous Nephrostomy Drainage
- Where
- 3 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Beni-Suef University
Kidney Stone, Ureteric Stone
Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg
Ureteral stenting is a common urological procedure performed to relieve obstruction and facilitate urinary drainage. Despite its effectiveness, stent-related symptoms (SRS) such as dysuria, frequency, urgency, flank pain, and…
- Trial name
- NCT07562282
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Ureteral Stone
Patient Positioning for Treatment of Proximal Ureteral Stones
Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment.
- Trial name
- NCT07601932
- Testing
- Reverse Trendelenburg Position, T-Tilt Position
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Ureteral Calculi
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
This randomized controlled trial compares the efficacy and safety of four treatment strategies for ureteral stone expulsion: Mirabegron alone, Tamsulosin alone, a combination of both, and standard conservative care.
- Trial name
- NCT07310797
- Testing
- Mirabegron, Tamsulosin
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Kidney Calculi, Ureteral Calculi
New Laser and Suction Sheath for Kidney Stone Treatment
The goal of this clinical trial is to learn if the combination of super pulsed thulium fiber laser (sTFL) with a flexible negative pressure suction sheath is more effective and safer than sTFL with a conventional sheath in…
- Trial name
- NCT06667466
- Testing
- Super Pulsed Thulium Fiber Laser (sTFL) + Flexible Negative Pressure Ureteral Access Sheath (UAS) Intervention, Super Pulsed Thulium Fiber Laser (sTFL) + Conventional Ureteral Access Sheath (UAS) Intervention
- Volunteers
- 140 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine