Clinical trials: Ureteroscopy
Nephrolithiasis
A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology
Flexible ureteroscopy is characterized as first-line therapy for the treatment of renal stones < 2 cm in size. This involves passing a flexible endoscope into the renal pelvis through the urethra, bladder and ureter in a…
- Trial name
- NCT04505956
- Testing
- Holmium laser lithotripsy with Moses Technology, Holmium laser lithotripsy without Moses Technology
- Where
- 6 sites in United States
- Volunteers
- 171 people
- Sponsor
- Vanderbilt University Medical Center
Renal Calculi
Tip-flexible Semi-rigid Ureterorenoscope Versus Flexible Ureteroscopy in Renal Calculi
This study evaluates the safety and efficacy of the novel tip-flexible semi-rigid ureterorenoscope for the treatment of renal calculi using a prospective, randomized multicentre trial design.
- Trial name
- NCT02426931
- Testing
- the tip-flexible ureterorenoscope, the classic flexible ureteroscope
- Volunteers
- 280 people
- Sponsor
- Ling Li, MD
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Nephrolithiasis, Flexible Ureteroscopy
Bendable Suction Ureteral Access Sheath Versus Conventional Ureteral Access Sheath in Management of Renal Stones Using Flexible Ureteroscopy
Urinary calculus is a globally recognized urological condition, with prevalence rates ranging from 1% to 13% across different geographical regions (1) Therapeutic approaches for renal calculi encompass extracorporeal shock wave…
- Trial name
- NCT06862141
- Testing
- bendable suction ureteral access sheath, conventional suction ureteral access sheath
- Where
- Egypt
- Volunteers
- 172 people
- Sponsor
- Menoufia University
Renal Calculi, Nephrolithiasis
Comparison Between Different Types of Flexible Ureteroscopes
The current study aims to compare the performance of three distinct single-use digital flexible ureteroscope types in terms of cost-effectiveness, postoperative complications, operating time, and stone-free rates (SFRs).
- Trial name
- FURS (NCT07360353)
- Testing
- LithoVue™ (Boston Scientific Corporation), WiScope® (OTU Medical Inc. (Silicon Valley, USA)), Single-Use Ureterorenoscope (Scivita Medical Technology Co., Ltd.)
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Renal Calculi
Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure
This study evaluates the safety and efficacy of the suctioning flexible ureteroscopy(SF-URS) with automatic control of renal pelvic pressure for the treatment of upper urinary calculi using a prospective, randomized design.
- Trial name
- NCT02734914
- Testing
- SF-URS with automatic control of RPP, conventional F-URS
- Volunteers
- 60 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Renal Stone, Nephrolithiasis
Impact Ureteral Sheath Design During Ureteroscopy
The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available.
- Conditions
- Renal Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT03349099
- Testing
- Cook Flexor, Boston Scientific Navigator
- Volunteers
- 95 people
- Sponsor
- The Cleveland Clinic
Symptoms and Signs, Pain
Stent-related Symptoms Comparison: Polaris Loop vs Vortek Double-J Stents
Prospective randomized controlled single-blind parallel-group trial in order to compare symptoms related to loop-tail (Polaris Loop) stents versus conventional double J (Vortek) stents after uncomplicated flexible URS.
- Conditions
- Symptoms and Signs, Pain, Renal Calculi
- Trial name
- NCT03344107
- Testing
- USSQ questionnaire administration after RIRS.
- Where
- Italy
- Volunteers
- 68 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Renal Stone, Pediatric
Flexible Ureteroscopy Versus Mini- Percutaneous Nephrolithotomy in Management of Pediatric Renal Stones Less Than 2 cm
This single-center, prospective, two-arm randomized controlled trial included 58 patients younger than 18 years who were allocated 1:1 to Mini-PCNL or FURS between June 2023 and December 2024.
- Trial name
- NCT07870200
- Testing
- Group A :Flexible ureteroscope group, Group B : Mini perc group
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Elsayed Abdelhalim Elsayed
Kidney Stones, Nephrolithiasis
6.3Fr Versus 7.5Fr Mini-Flexible Ureteroscopy for Renal Stones (MINI-FURS)
This prospective, randomized, single-blinded, non-inferiority clinical trial will compare the clinical outcomes and cost-effectiveness of two mini-flexible ureteroscopes (6.3Fr and 7.5Fr) used during flexible ureteroscopy for the…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- MINI-FURS (NCT07798336)
- Testing
- 6.3Fr Mini-Flexible Ureteroscope, 7.5Fr Mini-Flexible Ureteroscope
- Where
- Canada
- Volunteers
- 308 people
- Sponsor
- Sault Area Hospital
Ureteric Stone, Stone Ureter
Semi-rigid Ureteroscopy Versus Flexible Ureteroscopy For the Treatment of Proximal Ureteric Stone
The present study is randomized in nature, comparing the stone free rate and complications rate between semi-rigid ureteroscopy (SR-URS) and Flexible Ureteroscopy (F-URS) for the treatment of Proximal Ureteric stone (PUS)…
- Trial name
- NCT04851171
- Testing
- Flexible Ureteroscopy, Semi-rigid Ureteroscopy
- Where
- Qatar
- Volunteers
- 140 people
- Sponsor
- Hamad Medical Corporation
Ureteroscopy, Operation Time
The Effect of Musical Video With Virtual Reality Goggles on Patient's Anxiety and Comfort During Ureteroscopy
The effect of musical video with virtual reality goggles on patient's anxiety and comfort during ureteroscopy
- Conditions
- Ureteroscopy, Operation Time, Music Listening
- Trial name
- NCT06914830
- Testing
- Musical video demonstration with virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Aydin Adnan Menderes University
Kidney Stone, Infection
Novel Antimicrobial Solution to Prevent Infections
Ureteroscopy is the most common surgical treatment for kidney stones. Although rare, sepsis after ureteroscopy can be a life-threatening complication, occuring in <3% of patients.
- Conditions
- Kidney Stone, Infection, Infection Associated With Catheter, Sepsis
- Trial name
- NCT07881822
- Testing
- antimicrobial irrigation
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Upper Urinary Tract Urothelial Carcinoma, Bladder Cancer
Single-Dose Intravesical Chemotherapy After Diagnostic URS
Study design This study is a Phase III, randomized, open-label, multi-center, global study to determine the efficacy of a single immediate intravesical chemotherapy instillation (SI) in the prophylaxis of intravesical recurrence…
- Trial name
- MINERVA (NCT05810623)
- Testing
- Intravesical Solution
- Where
- 2 sites in Austria
- Volunteers
- 394 people, healthy volunteers welcome
- Sponsor
- David D'Andrea
Ureteroscopy
The Role of Ureteral Stenting Following Uncomplicated Ureteroscopy for Ureteral and Renal Stones: A Randomized, Controlled Trial
It is well established that uncomplicated distal ureteroscopy can be safely performed without leaving a ureteral stent. However, many urologists continue to leave ureteral stents following uncomplicated ureteroscopy, regardless…
- Trial name
- NCT03130907
- Testing
- Placement of ureteral stent
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- San Antonio Uniformed Services Health Education Consortium
Nephrolithiasis, Alpha Blocker
Alpha-Blockers Prior to Ureteral Access Sheath Placement in Flexible Ureteroscopy: A Randomized Prospective Study
This study aims to evaluate whether the use of alpha-blockers before flexible ureterorenolithotripsy facilitates the passage of the ureteral access sheath.
- Conditions
- Nephrolithiasis, Alpha Blocker, Ureteral Access Sheath
- Trial name
- ALFA-URS (NCT07124299)
- Testing
- Experimental: Alpha-blocker group, No intervention (observational study)
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Pedro de Figueiredo Buchalla
Kidney Stone
The Effect of Ureteric Stent Tethers on Patient Symptoms and Urinary Infection
RESEARCH QUESTION Do ureteric stents with tethers, left in-situ for 1-2 weeks, increase the rate of stent bacterial colonization, urinary bacterial colonization and stent related lower urinary tract symptoms compared to stents…
- Trial name
- NCT01812772
- Testing
- Double J-stent with a long tether, Double J-stent without a long tether
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Unity Health Toronto
Ureteral Diseases
Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy
A prospective, multi-center, non-randomized trial to demonstrate safety and device performance of the ADVA-Tec Uriprene® Degradable Temporary Ureteral Stent.
- Trial name
- URIPRENE (NCT04565795)
- Testing
- Uriprene® Degradable Temporary Ureteral Stent
- Where
- 4 sites in United States
- Volunteers
- 87 people
- Sponsor
- Adva-Tec
Stone, Kidney
FANS-Optimization of Irrigation and Suction Parameters in RIRS
Kidney stones are commonly treated with flexible ureteroscopy, a minimally invasive procedure in which a small scope is passed through the urinary tract to reach and treat stones in the kidney.
- Trial name
- NCT07840482
- Testing
- ClearPetra™ FANS - High-Flow Setting, ClearPetra™ FANS - Moderate-Flow Setting
- Volunteers
- 100 people
- Sponsor
- University of Kansas Medical Center
Ureteric Stone, Flexible Ureteroscopy
Flexible vs Semi-rigid URS
To compare the efficacy, safety, success rate, operative time, and cost-effectiveness of flexible ureteroscopy versus semirigid ureteroscopy in the management of upper ureteric stones smaller than 2 cm.
- Conditions
- Ureteric Stone, Flexible Ureteroscopy, Upper Urinary Tract Stones
- Trial name
- NCT07247617
- Testing
- Flexible URS, Semi-Rigid URS
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University