Clinical trials: Urethral Stricture
Urethral Stricture, Male
Holmium: YAG Versus Cold Knife Internal Urethrotomy in Management of Short Urethral Strictures
Urethral stricture disease is defined as narrowing of the urethral lumen because of fibrosis, which occurs in urethral mucosa and surrounding tissues. The etiology could be congenital, iatrogenic, infectious, or idiopathic.
- Trial name
- NCT04650347
- Testing
- visualized internal urethrotomy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Urethral Stricture
Role of Uttarbasti in the Management of Mutra Marga Sankoch (Urethral Stricture)
Uttarbasti is per urethral administration of medicated oil which has been recommended by Sushrut for urinary track disorders. As far as conventional surgery is concerned urethral stricture still remains a challenge due to post…
- Trial name
- NCT00535717
- Testing
- uttarbasti (per urethral administration of medicated oil )
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maharashtra University of Health Sciences
Urethra Stricture
LishitonglinUS-01 Trial
This study intends to conduct a prospective, randomized, double-blind, placebo-controlled trial to investigate the efficacy and safety of Lishi Tonglin Granule (a hospital-formulated innovative prescription) developed in our…
- Trial name
- NCT07769060
- Testing
- Lishitonglin Formula granules
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University First Hospital
Urethral Stricture, Erectile Dysfunction
Comparison Between Excision And Primary Anastomosis Urethroplasty And Tunica Vaginalis Graft Urethroplasty.
Urethroplasty is considered the gold standard for the treatment of urethral stricture disease, with a success rate of more than 93% in terms of stricture recurrence.
- Trial name
- NCT07668973
- Testing
- Excision and Primary Anastomosis Urethroplasty, Tunica Vaginalis Graft Urethroplasty
- Volunteers
- 94 people
- Sponsor
- Sahiwal medical college sahiwal
Urethral Stricture, Surgery
VeSpAR: Comparing Vessel-Sparing Anastomotic Repair and Transecting Anastomotic Repair in Isolated Short Bulbar Strictures.
The investigators want to verify whether the surgical outcome of vessel-sparing anastomotic repair in isolated short bulbar urethral strictures is not inferior to the surgical outcome of transecting anastomotic repair.
- Conditions
- Urethral Stricture, Surgery, Urologic Diseases
- Trial name
- VeSpAR (NCT03572348)
- Testing
- Transecting anastomotic repair (tAR), Vessel-sparing anastomotic repair (vsAR)
- Where
- 13 sites in United States, Argentina and 6 more
- Volunteers
- 100 people
- Sponsor
- University Hospital, Ghent
Urethral Stricture
Effectiveness of Intermittent Bladder Catheterization (IBC) in Reducing Recurrence of Urethral Stricture
The goal of this randomized controlled trial is to To assess the effectiveness of intermittent bladder catheterization (IBC) in reducing the recurrence of urethral stricture among females in tertiary care hospital, Lahore.
- Trial name
- NCT06064968
- Testing
- Intermittent bladder catheterization
- Where
- Pakistan
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Lahore
Urethral Stricture
Effect of Mitomycin C on Urethral Stricture Recurrence After Internal Urethrotomy
The aim of this study is to evaluate the efficacy of local injected mitomycin C at the time of internal urethrotomy in order to prevent the recurrence of urethral strictures.
- Trial name
- NCT00918528
- Testing
- Internal urethrotomy, Mitomycin C - local injection
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Stricture Urethra
The Effect of Platelet Rich Plasma Injection on Post Internal Urethrotomy Stricture Recurrence
The effect of platelet rich plasma injection on post internal urethrotomy stricture recurrence
- Trial name
- prp vs VIU (NCT07837167)
- Testing
- PRP injection, VIU
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Benha University
Urethral Stricture
Urethral Stricture Database
Establishment of a clinical urethral stricture database for a prospective longitudinal cohort study.
- Trial name
- NCT06362083
- Testing
- Questionnaires and data collection
- Where
- Austria
- Volunteers
- 500 people
- Sponsor
- Medical University of Graz
Urologic Diseases, Male Urogenital Diseases
Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures
This is a Phase I clinical study to determine the safety and efficacy of using autologous, engineered urethral constructs for the treatment of urethral strictures in adult males.
- Conditions
- Urologic Diseases, Male Urogenital Diseases, Urethral Stricture, Urethral Injury
- Trial name
- NCT03258658
- Testing
- Autologous Engineered Urethral Construct
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Urethral Stricture, Fat Graft
Feasibility and Therapeutic Potential of Free Fat Grafts in the Treatment of Urethral Strictures
In this study the investigators investigate the feasibility and therapeutic potential of free autologous fat grafting combined to direct visual urethrotomy (DVIU) in the treatment of urethral strictures.
- Trial name
- UREGRAFT (NCT04161365)
- Testing
- Direct visual urethrotomy, Autologous fat grafting
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Hannes Kortekangas
Benign Prostate Obstruction (BPO)
The Effects of Holmium Laser Enucleation and Thulium Laser Enucleation on Continence, Urethral Stricture, and Sexual Function in Benign Prostatic Hyperplasia
This study aims to evaluate the effects of Holmium Laser Enucleation of the Prostate (HoLEP) and Thulium Laser Enucleation of the Prostate (ThuLEP), performed for the treatment of benign prostatic hyperplasia (BPH), on the…
- Trial name
- EHTCUS (NCT07334730)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- TC Erciyes University
Anterior Urethral Stricture, Male
Anatomical and Functional Outcome of PSG Vs BMG for Urethral Substitution in Long Segment Anterior Urethral Strictures
This study aims to compare the penile skin graft and buccal mucosal graft for substitution of long anterior urethral strictures using one-sided dorsal perineal approach.
- Trial name
- NCT06056856
- Testing
- Penile skin graft substituttion urethroplasty, Buccal Mucosal Graft substitution urethroplasty
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Urethral Stricture
Memokath® 044TW Stent for Treatment of Urethral Stricture
The purpose of this study is to evaluate if the placement of a temporary urethral stent for up to 12 months, following dilation or internal urethrotomy (cutting open), results in a higher rate of urethral patency during the first…
- Trial name
- NCT00270504
- Testing
- Memokath stenting
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Pnn Medical DK
Urethral Stricture, Male
Peri-operative Oral Pain Control Following Buccal Graft Urethroplasty
Patients undergoing buccal urethroplasty will often have significant post-operative oral pain from the graft site. Various graft harvest techniques and methods for post-harvest hemostasis including graft site closure have been…
- Trial name
- Buccal (NCT05300685)
- Testing
- Standard Buccal Harvest, Basic buccal procedure + Long acting local, Basic buccal procedure + Buccal block
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Francisco
Penile Skin, Buccal Mucosal Graft
Penile Skin Versus Buccal Mucosal Graft in Augmentation Urethroplasty for Long Anterior Urethral Stricture
The aim of this study is to analyze the outcomes of dorsal onlay buccal mucosal graft (BMG) and penile skin graft (PSG) urethroplasty in the management of long segment bulbar urethral stricture.
- Conditions
- Penile Skin, Buccal Mucosal Graft, Augmentation, Urethroplasty
- Trial name
- NCT07074717
- Testing
- Buccal Mucosal Graft (BMG) Urethroplasty, Penile Skin Graft (PSG) Urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University
Urethral Stricture
Mobile Health Application to Improve Patient Satisfaction After Urethroplasty
Create a custom urethroplasty mobile application that will guide patients through through the surgical process.
- Trial name
- NCT06384066
- Testing
- GetWell Mobile Application, Standard of Care
- Where
- United States
- Sponsor
- Northwestern University
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Urethral Stricture
Factors Predicting Urethral Stricture Recurrence After Dorsal Onlay Augmented, Buccal Mucosal Graft Urethroplasty
In this observational study, the investigators will evaluate potential risk factors associated with urethral stricture recurrence after augmentation anterior urethroplasty using dorsal onlay buccal mucosal Graft during the past…
- Trial name
- NCT04357080
- Testing
- Urethroplasty
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Al-Azhar University
Urethral Stricture, Bulbar
Optimal Duration of Foley Catheter After Bulbar Urethroplasty
The goal of this clinical trial is to learn when is the best time to remove a Foley catheter (tube used to drain urine from the bladder) after surgery in adult men who have a specific type of urethral stricture disease (narrowing…
- Trial name
- NCT07220980
- Testing
- Early catheter removal, Later catheter removal
- Where
- 4 sites in United States
- Volunteers
- 320 people
- Sponsor
- Jane Kurtzman