Clinical trials: Urgency Urinary
Urgency Urinary Incontinence
Investigation of Brain Mechanisms Involved in Urgency Urinary Incontinence
This is a randomized double-blind crossover trial of trospium and placebo in women with urgency urinary incontinence, with evaluation (history, physical, incontinence evaluation and brain MRI) at baseline, and after each course…
- Trial name
- NCT04227184
- Testing
- Trospium
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Becky Clarkson
Interstitial Cystitis
Phase II Study Efficacy and Safety of Two Dosing Regimens of MN-001 in Patients With Interstitial Cystitis
To evaluate the safety and efficacy of 8 weeks of treatment with MN-001 at 500 mg bid, 500 mg once daily vs. placebo in patients with Interstitial Cystitis.
- Trial name
- NCT00295854
- Testing
- MN-001 BID, MN-001
- Where
- 28 sites in United States
- Volunteers
- 296 people
- Sponsor
- MediciNova
Radiation Exposure, Overactive Bladder
Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement
Fluoroscopy is performed when placing a lead during a sacral neuromodulation procedure. During lead placement, subjects will receive either conventional or experimental fluoroscopic settings.
- Conditions
- Radiation Exposure, Overactive Bladder, Urge Incontinence, Urgency-frequency Syndrome
- Trial name
- NCT04527445
- Testing
- Reduced radiation fluoroscopy, Conventional fluoroscopy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Loma Linda University
Overactive Bladder
An Implantable Microstimulator for the Chronic Treatment of Urinary Urgency-Frequency Syndrome
The goal of this study is to investigate the safety and effectiveness of a new implanted device designed to treat Urinary Urgency-Frequency Syndrome.
- Trial name
- NCT00131573
- Testing
- bion
- Where
- 11 sites in United States
- Volunteers
- 118 people
- Sponsor
- Boston Scientific Corporation
Overactive Bladder, Bladder, Overactive
Transvaginal Botulinum Toxin A Chemodenervation for Overactive Bladder
Overactive bladder (OAB) is a highly prevalent disease process that, when refractory to oral medication therapy, can be effectively managed with injection of botulinum toxin A (BTA) into the detrusor muscle of the bladder.
- Conditions
- Overactive Bladder, Bladder, Overactive, Urge Incontinence, Urgency Urinary
- Trial name
- FETOC (NCT05463822)
- Testing
- Transvaginal botulinum toxin A (BTA) injection
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Bladder Pain and Discomfort, Urinary Urgency and Frequency
Sensory Sensitivity and Urinary Symptoms in the Female Population
Bladder pain and discomfort, as well as urinary urgency and frequency, are bothersome symptoms seen frequently in the general population.
- Conditions
- Bladder Pain and Discomfort, Urinary Urgency and Frequency, Bothersome Symptoms
- Trial name
- NCT01978002
- Testing
- Pain sensitivity testing, Urodynamic testing
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Urinary Incontinence, Urge
Mindfulness + tDCS to Reduce Urgency Incontinence in Women
Urge urinary incontinence (UUI) is a common problem in older women, which vastly reduces quality of life. UUI sufferers frequently report situational triggers (e.g.
- Trial name
- NCT04652869
- Testing
- Transcranial direct current stimulation, Mindfulness
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Cynthia Conklin
Mixed Urinary Incontinence
Implantation of an Adjustable Suburethral Sling is an Effective Treatment Method for Patients With Mixed Urinary Incontinence of Moderate to Severe Severity, After Which the Severity of the Stress and Urgency Components is Reduced.
The aim of this clinical study is to optimize treatment outcomes in patients with mixed forms of urinary incontinence by implanting an adjustable suburethral sling and to determine factors influencing treatment effectiveness.
- Trial name
- NCT07564323
- Testing
- implantation of an adjustable suburethral sling
- Volunteers
- 156 people
- Sponsor
- Saint Petersburg State University, Russia
Overactive Bladder
Efficacy and Safety of Botulinum Toxin A for the Treatment of Refractory Overactive Bladder.
Overactive bladder induce urgency, urge incontinence, nocturia and pollakiuria. This condition is often resistant to anticholinergic drugs used as a first line treatment for this purpose.
- Trial name
- NCT00231491
- Testing
- Botulinum Toxin A (Botox )
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urge Urinary Incontinence
The Long Term Outcomes of Rehabilitation and Drug Treatment for in Urgency Urinary Incontinence
Urinary Urge Incontinence (UUI) is the involuntary urine loss associated with a strong sensation to void. UUI usually associated with reduced bladder capacity. The pathophysiology is unclear.
- Trial name
- UUI (NCT00498888)
- Testing
- tolterodine, bladder training, pelvic floor muscle training
- Where
- Israel
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems