Clinical trials: Uric Acid
Coronary Artery Disease, Hyperuricemia
The Long Term Effect of Low Dose Aspirin on Uric Acid in Chinese Patients With Coronary Artery Disease（AURORA）
The deleterious effects of hyperuricemia (HUA) on cardiovascular disease (CVD) were well established. Aspirin is the most commonly prescribed antiplatelet agent for primary or secondary prophylaxis of CVD.
- Trial name
- AURORA (NCT03691688)
- Testing
- Aspirin 100 mg, Clopidogrel 75mg
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shanghai Zhongshan Hospital
Hyperuricemia, Metabolic Syndrome
Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction
Hyperuricemia is an additional risk factor for cardiovascular disease, associating with left ventricular diastolic dysfunction in individuals with metabolic syndrome.
- Conditions
- Hyperuricemia, Metabolic Syndrome, Left Ventricular Diastolic Dysfunction
- Trial name
- NCT03534037
- Testing
- Febuxostat 40 mg, Benzbromarone 50mg, Control
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Defense Medical Center, Taiwan
Obesity, Dyslipidemia
Meta-analyses of the Effect of Sucrose Versus High Fructose Corn Syrup on Cardiometabolic Risk
The rise in high fructose corn syrup (HFCS) consumption over the past 40 years since its introduction as a popular sweetener in the United States has led to much concern regarding its contribution to the rise in obesity (1)…
- Conditions
- Obesity, Dyslipidemia, Prediabetes, Dysglycemia
- Trial name
- NCT02702479
- Testing
- High Fructose Corn Syrup, Sucrose
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Hypertension, Left Ventricular Hypertrophy
Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE)
Studying the causal roles of components of the renin-angiotensin-aldosterone system (including angiotensin-(1-7) (Ang-(1-7)), angiotensin-converting enzyme 2 (ACE2), Ang II, and ACE), uric acid, and klotho in pediatric…
- Conditions
- Hypertension, Left Ventricular Hypertrophy, Left Ventricular Dysfunction, Left Atrial Dilatation
- Trial name
- PHRASE (NCT04752293)
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Urolithiasis, Renal Stones
The Predictors of Successful Oral Dissolution Therapy in Radiolucent Renal Stones; A Prospective Evaluation
The aim of the study is to evaluate the predictors of success of oral dissolution therapy in radiolucent renal stones in a large series of patients from a tertiary referral center in order to define the optimum case scenarios…
- Trial name
- NCT02373384
- Testing
- Oral alkalinization (Potassium citrate, Allopurinol), Life style modification, Dietary recommendations (decrease purine rich diet as red meat and fish, increase vegetables)
- Where
- Egypt
- Volunteers
- 182 people
- Sponsor
- Mansoura University
Inflammation
Montmorency Cherry Juice and Uric Acid Metabolism
Cherries have been show to possess the ability to reduce uric acid concentrations and inflammation. Tart Montmorency cherries possess a higher concentration of the plant compounds than other cherries and hence makes the…
- Trial name
- NCT01825070
- Testing
- Montmorency cherry concentrate
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Blood Pressure, Gout
The Blood Pressure Effects of Febuxostat in Patients Previously Treated With Allopurinol: A Pilot Study
Hyperuricemia (high uric acid level) has been correlated to hypertension (high blood pressure) and overall cardiovascular disease risk in several studies.
- Trial name
- NCT01701622
- Testing
- febuxostat
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Mississippi Medical Center
Multiple Sclerosis, Relapsing-Remitting
Treatment of Multiple Sclerosis Using Over the Counter Inosine
The purpose of this study is to determine whether raising low levels of the natural antioxidant uric acid by the administration of a precursor, inosine, has any therapeutic effect on the progression of Relapsing Remitting…
- Trial name
- NCT00067327
- Testing
- Inosine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Diabetes Mellitus
Association Between Uric Acid / High Density Lipoprotein Ratio and Monocyte / High Density Lipoprotein Ratio With Diabetic Complications
Type 2 diabetes mellitus (T2DM) poses a formidable global health challenge, with complications arising in both the microvascular and macrovascular domains as glycemic control worsens.the aim of the study to evaluate uric acid /…
- Trial name
- NCT06754813
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Uric Acid Stones
The Effective of Potassium Sodium Hydrogen Citrate in Treating Uric Acid Stones Using Gut Microbiota and Metabolomics.
The goal of this observational study is to investigate the alterations in gut microbiota and metabolites among patients with uric acid stones following the administration of potassium sodium hydrogen citrate.
- Trial name
- NCT06118320
- Testing
- Potassium sodium hydrogen citrate
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Cheng Cao
Obesity
A Comparison of the Metabolic Effects of Fructose, Glucose, High Fructose Corn Syrup and Sucrose at Normal Population Consumed Levels in Adults Aged 20-60 Years Old
The purpose of this study is to investigate the acute and chronic effects of consumption fructose containing sugars and glucose in a real word setting when consumed in a manner and amount typical in the American diet.
- Trial name
- NCT01797042
- Testing
- Dietary Compliance
- Where
- United States
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Rippe Lifestyle Institute
Pre-Eclampsia, Hyperuricemia
Xanthine Oxidase and Uric Acid Origin in Preeclamptic Women
Findings regarding the presence of xanthine oxidase and uric acid in different blood locations is important in preeclamptic women.
- Trial name
- NCT04463940
- Testing
- No intervention
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Barzilai Medical Center