Clinical trials: Urinary
Urinary Bladder Neoplasms, Colorectal Cancer
A First-in-human Study to Evaluate the Safety and Tolerability of AZD8853 in Participants With Selected Advanced/Metastatic Solid Tumours
A Phase I/IIa First-in-human, Open-label Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy of AZD8853 in Participants with Selected Advanced/Metastatic Solid Tumours.
- Conditions
- Urinary Bladder Neoplasms, Colorectal Cancer, Carcinoma, Non-Small-Cell Lung
- Trial name
- NCT05397171
- Testing
- AZD8853, Zirconium-89 crefmirlimab berdoxam
- Where
- 6 sites in United States, Canada
- Volunteers
- 17 people
- Sponsor
- AstraZeneca
Overactive Bladder Syndrome (OABS)
Effect of BT and PFET on Urinary Symptoms and Quality of Life in Patients With OABS
The aim of this study was to examine the effects of bladder training and pelvic floor exercise training programs given in addition to Botulinum Toxin-A (BTx-A) application on urinary symptoms and quality of life in patients with…
- Trial name
- OABS/BT/PFET (NCT06209333)
- Testing
- Standard Patient Education, bladder training, pelvic floor exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Urinary Incontinence , Stress, Urinary Incontinence (UI)
Effectiveness of DNS on Incontinence Severity, Pelvic Floor Strength and QoL in Urinary Incontinence
The aim of this study is to investigate the effects of Dynamic Neuromuscular Stabilization (DNS) Training on incontinence severity, pelvic floor muscle strength, and quality of life in women with Urinary Incontinence, compared to…
- Conditions
- Urinary Incontinence , Stress, Urinary Incontinence (UI), Exercise
- Trial name
- NCT06627452
- Testing
- Dynamic Neuromuscular Stabilization Training, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Istanbul University - Cerrahpasa
Urinary Catheters, Nursing Care
The Effect of QR Code-Based Video Training on Knowledge Level, Self-Management, and Self-Efficacy in Patients With Urinary Catheters: A Randomized Controlled Study
This clinical study aims to find out if a QR code-based educational video helps adult men manage their urinary catheters after surgery. The study focuses on men who have a catheter after robotic prostate surgery.
- Trial name
- RCS (NCT07884409)
- Testing
- Patient education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Stress Urinary Incontinence
Comparing Minisling to Tension Free Vaginal Tape in Mangement of Stress Urinary Incontinence
Based on previous studies the single incision minisling is an easy less invasive procedure with fewer complications and cure rate similar to conventional midurethral slings in the treatment of female stress urinary incontinence.
- Trial name
- NCT02263534
- Testing
- single incision minisling, tension free vaginal tape
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Ain Shams University
Urinary Incontinence
Collecting Real-life Data for the Updated TENA SmartCare Change Indicator.
This study is an explorative, open, single-arm clinical investigation to collect real-life measurement data in order to assess the mathematical algorithms involved in TENA SmartCare Change Indicator.
- Trial name
- NCT06092099
- Testing
- TENA SmartCare Change Indicator
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Essity Hygiene and Health AB
Urinary Retention
First-in-man Safety and Efficacy Trial of a Novel Non-invasive Bladder Emptying Device: The NIBED Study
The non-invasive bladder emptying device (NIBED) is a handheld medical device that is applied to the penis during urinating to aid bladder emptying in urinary retention patients with increased residual urine volume.
- Trial name
- NIBED pilot (NCT04919798)
- Testing
- Non-invasive bladder emptying device
- Where
- Switzerland
- Volunteers
- 10 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urinary Tract Infections
A Phase IV Study of Cipro XR in Uncomplicated UTI
Safety and efficacy of Cipro XR in a naturalistic setting and the effectiveness of an educational brochure. - Women with urinary tract infections were treated with Cipro XR.
- Trial name
- EXPRESS (NCT00663806)
- Testing
- Cipro XR (Ciprofloxacin, BAYQ3939)
- Volunteers
- 7,614 people
- Sponsor
- Bayer
Non-muscle-invasive Bladder Cancer
T-Control® Safety for Cytostatics Management
The goal of this pilot clinical trial is to know if this study is feasable in terms of design, recruitment and interventions, as well as gather preliminary data to determine if the T-Control® catheter is safer than the…
- Trial name
- NCT06678633
- Testing
- T-Control® (experimental), Folysil® (control)
- Volunteers
- 16 people
- Sponsor
- Rethink Medical SL
Recurrent Urinary Tract Infection
The Effect of ASTARTE™ on Recurrent Urinary Tract Infection
Investigate the effect of dietary supplements/probiotic ASTARTE™ ( L. crispatus, L. rhamnosus, L. jensenii, L. gasseri) on the microbiome composition in the intestine and vagina and thereby a reduction of risk factors for the…
- Trial name
- rUTI (NCT05553652)
- Testing
- ASTARTE™ oral capsules
- Where
- Denmark
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Recurrent UTIs, Cystitis Recurrent
Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections
The goal of this clinical trial is to learn if the drug Nitrofurantoin (NF) taken as a daily antibiotic, works to treat cystitis compared to electrofulguration (EF) and Nitrofurantoin (NF) daily antibiotic.
- Trial name
- NCT06907199
- Testing
- Electrofulguration (EF), Nitrofurantoin (NF)
- Where
- 2 sites in United States
- Volunteers
- 104 people
- Sponsor
- University of Texas Southwestern Medical Center
Alkaptonuria
Dose Response Study of Nitisinone in Alkaptonuria
SONIA 1 is an international, multicentre, randomised, open-label, no-treatment controlled, parallel group, dose-response study to investigate the effect of once daily nitisinone on 24-hour urinary homogentisic acid excretion in…
- Trial name
- SONIA1 (NCT01828463)
- Testing
- Nitisinone
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Liverpool
Urinary Incontinence
The Effects of the Pelvic Floor and Abdominal Muscle Training on Urinary Incontinence
To investigate the effects of the pelvic floor and abdominal muscle training on the severity of incontinence in women with stress and mixed urinary incontinence.
- Trial name
- NCT05549193
- Testing
- Exercises Training
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Gazi University
Non-muscle Invasive Bladder Cancer (NMIBC)
A Study of Intravesical FL115 Alone or in Combination With BCG in Non-Muscle Invasive Bladder Cancer
The study is to evaluate the safety and tolerability of intravesical FL115 alone or in combination with BCG in the patients with NMIBC, and to determine the RP2D of FL115 in combination with BCG.
- Trial name
- NCT07122414
- Testing
- FL115, FL115+BCG
- Where
- 12 sites in China
- Volunteers
- 80 people
- Sponsor
- Suzhou Forlong Biotechnology Co., Ltd
Healthy
Pubic Hair and the Urinary and Vaginal Microbiome
This research study seeks to find if there is a connection between the presence of pubic hair and the type of bacteria that live in the vagina and bladder.
- Trial name
- NCT03272204
- Testing
- No pubic hair, Pubic Hair
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Margaret Mueller
Urinary Incontinence Stress
Open Label Phase III Duloxetine Study for Stress Urinary Incontinence
The purpose of this study is to monitor the long term safety of duloxetine in the treatment of stress urinary incontinence.
- Trial name
- NCT00191204
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 363 people
- Sponsor
- Eli Lilly and Company
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms (LUTS)
Safety and Effectiveness Study of the Zenflow Spring System
Evaluate the safety and effectiveness of the Zenflow Spring System in relieving LUTS associated with BPH.
- Trial name
- BREEZE (NCT04987138)
- Testing
- Zenflow Spring System
- Where
- 7 sites in United States
- Volunteers
- 279 people
- Sponsor
- Zenflow, Inc.
Urinary Incontinence
Screening for Urinary Incontinence by Primary Care Providers
The purpose of this study is to: Assess the rate of screening for urinary incontinence (UI) in women by their primary care providers Identify the type of screening used by primary care providers Identify barriers to screening for…
- Trial name
- NCT00178334
- Volunteers
- 554 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breast Cancer, Bladder Cancer
Cancer in Patients on Dapagliflozin and Other Antidiabetic Treatment
The primary objectives of this study are (1) to compare the incidence of breast cancer, by insulin use at cohort entry, among females with type 2 diabetes who are new users of dapagliflozin and females who are new users of…
- Trial name
- NCT02695121
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 2,133,575 people
- Sponsor
- AstraZeneca
Urinary Tract Infections
Fractional CO2 Vaginal LASER Therapy for Recurrent Urinary Tract Infection
Randomized controlled trial to determine clinical and microbiome difference between fractional CO2 Laser and vaginal estrogen in treating patients with recurrent urinary tract infection (UTI).
- Trial name
- NCT04301934
- Testing
- Mona Lisa Touch, Conjugated estrogen, Estradiol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic