Clinical trials: Urinary Bladder Diseases\Urologic Diseases
Cystitis, Interstitial
Safety and Efficacy of AGN 203818 for Pain Associated With Painful Bladder Syndrome/Interstitial Cystitis
This study will explore the safety and effectiveness of different doses of AGN 203818 in treating the pain associated with painful bladder syndrome/interstitial cystitis
- Trial name
- NCT00380783
- Testing
- AGN 203818
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Allergan
Overactive Bladder, Non Obstructive Urinary Retention
Sacral Neuromodulation and Pudendal Somatic Afferents
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth…
- Trial name
- NCT03614754
- Testing
- Somatosensory evoked potentials
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Universiteit Antwerpen
Pelvic Organ Prolapse, Cystocele
SCP vs HUSLS for Pelvic Organ Prolapse Repair
The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT02800512
- Testing
- Robotic sacrocolpopexy, high uterosacral ligament suspension
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Loma Linda University
Non-muscle Invasive Bladder Cancer
"En Bloc" Resection of NMIBC: a Prospective， Single Centre，Randomized Study
The traditional method of choice for intravesical resection of bladder tumors is conventional transurethral resection of bladder tumor (cTURBT).
- Trial name
- NCT03221062
- Testing
- Laser en Bloc Resection
- Volunteers
- 180 people
- Sponsor
- Tongji Hospital
Male Urogenital Diseases, Genital Diseases, Male
Office Based Transperineal Laser Ablation for Benign Prostatic Hyperplasia HYPERPLASIA
This study is set up as a phase I-II prospective, single center, interventional pilot study carried in Office setting under local anesthesia.
- Conditions
- Male Urogenital Diseases, Genital Diseases, Male, Prostatic Disease, Prostatic Hyperplasia
- Trial name
- NCT04760483
- Testing
- SoracteLite(TM) TPLA for BPH
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Urological Research Network, LLC
Non-muscle Invasive Bladder Cancer, Cystoscopy
Biomarkers of Recurrence and Progression in Non-muscle Invasive Bladder Cancer
Bladder cancer (BC) is one of the most common type of cancer globally. Due to its high incidence rate, high risk of recurrence and progression, and frequent cystoscopy surveillance, BC contributes to major healthcare costs across…
- Conditions
- Non-muscle Invasive Bladder Cancer, Cystoscopy, Recurrence, Progression
- Trial name
- NCT06235853
- Testing
- Blood serum: sUPAR, PAI-1, IL-8., Urine: IL-8, APOE, VEGF.
- Where
- Poland
- Volunteers
- 240 people
- Sponsor
- Wroclaw Medical University
Non-Muscle Invasive Bladder Cancer
Machine Learning-Based Prediction of BCG Response in High-Risk Non-Muscle Invasive Bladder Cancer Patients
This prospective study aims at using Artificial intelligence to create a helpful unbiased machine learning-based model that predicts BCG unresponsiveness in high risk BCG-naïve NMIBC patients incorporating all potential…
- Trial name
- NCT05332353
- Testing
- Bacillus Calmette-Guerin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Stem Cell Transplant Complications
Hyperbaric Oxygen Therapy for Hemorrhagic Cystitis Post HSCT
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potentially curative therapy for many malignant or nonmalignant hematological diseases.
- Trial name
- NCT04502628
- Testing
- Hyperbaric oxygen therapy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Shandong Provincial Hospital
Bladder Cancer
Measurements of Sexual Steroids' Concentrations in Prostatic Tissue
In the investigators's previous work, measurements of intra-prostatic concentrations of sex steroids were determined on samples taken from the operating room using a punch.
- Trial name
- Pré-HORM (NCT04256161)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Hopital Foch
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Combination Chemotherapy in Treating Patients With Advanced Bladder or Kidney Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003342
- Testing
- filgrastim, carboplatin, doxorubicin hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Interstitial Cystitis, Bladder Pain Syndrome
Supervised Exercise as a Therapeutic Strategy for Interstitial Cystitis/Bladder Pain Syndrome
In this study, the efficacy of exercise to improve interstitial cystitis/bladder pain syndrome symptoms and quality of life will be investigated.
- Trial name
- IC/BPS (NCT05699551)
- Testing
- Exercise regimen
- Sponsor
- Wake Forest University Health Sciences
HoLEP, Trifecta Achievement
Predictors of Trifecta Achievement After HoLEP
Holmium laser enucleation of the prostate (HoLEP) is a surgical treatment option for men experiencing bothersome lower urinary tract symptoms due to an enlarged prostate.
- Conditions
- HoLEP, Trifecta Achievement, Urinary Incontinence Following Surgical Procedure, Clavien Dindo Surgical Complication Scale
- Trial name
- ReMIUS-BPO (NCT07429994)
- Testing
- Transurethral Holmium Laser Enuclation of the Prostate
- Where
- Turkey (Türkiye)
- Volunteers
- 604 people
- Sponsor
- Ondokuz Mayıs University
Overactive Bladder
Feasibility of "At-home" Titration of Solifenacin
This is an open-label single center trial to study improvements in symptom bother and quality of life in overactive bladder patients self titrating solifenacin 5mg and 10 mg.
- Trial name
- NCT00759577
- Testing
- Solifenacin
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Bladder Cancer, Disease Progression
In the Prediction of Recurrence and Progression of NMIBC; EORTC or CUETO or Both?
Investigators aimed to evaluate the performance of The European Organization for Research and Treatment of Cancer(EORTC) and the Spanish Urology Association for Oncological Treatment(CUETO) risk tables on all non-muscle invasive…
- Conditions
- Bladder Cancer, Disease Progression, Recurrent Bladder Cancer
- Trial name
- NCT03174912
- Testing
- Intravesical BCG instillation
- Volunteers
- 400 people
- Sponsor
- Ankara Training and Research Hospital
Overactive Bladder
Over Active Bladder Patients Having Sling Surgery
The purpose of this study is to determine whether treatment with anti-muscarinic medications following sub-urethral sling procedures improves overall subjective and objective outcomes in women with mixed incontinence with primary…
- Trial name
- NCT00852696
- Testing
- Solifenacin
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Cleveland Clinic Florida
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection.
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Ann Arbor Stage I Lymphoma, Ann Arbor Stage II Lymphoma
- Trial name
- NCT05334069
- Testing
- Questionnaire Administration, Biospecimen Collection
- Where
- 751 sites in United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Overactive Bladder
Clinical Feasibility Study, Implantable Tibial Nerve Stimulator (ITNS)
Study objectives: To report feasibility data for safety and effectiveness of the study device. Study device: Nine Continents Medical implantable tibial nerve stimulator (ITNS) model 9C-680 with programmer model 9C-580.
- Trial name
- NCT04115228
- Testing
- Implantation and neuromodulation therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nine Continents Medical, Inc.
Stress Urinary Incontinence, Urge Urinary Incontinence
Transcutaneous Mechanical Nerve Stimulation in the Treatment of Incontinence
During transcutaneous mechanical nerve stimulation in spinal cord injured men an increase in pressure was observed in the external urethral sphincter along with an increase in bladder capacity.
- Trial name
- NCT01366066
- Testing
- Transcutaneous mechanical nerve stimulation
- Where
- Denmark
- Volunteers
- 4 people
- Sponsor
- Copenhagen University Hospital at Herlev
Urinary Incontinence, Daytime Wetting
The Voided Urinary, Perineal, and Faecal Microbiota Among Children and Adolescents - the PpUF-study.
The aim of this study is to investigate whether the voided urinary, perineal/preputial, and the fecal microbiota are different between children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI)…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urologic Diseases
- Trial name
- NCT07535619
- Where
- 4 sites in Denmark
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Cancer
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00049296
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center