Clinical trials: Urinary Bladder Overactive, open to volunteers
Overactive Bladder
Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis
The aim of the study is to assess the association between bladder sensations progression during bladder filling and severity of Overactive bladder (OAB) in patients with multiple sclerosis.
- Trial name
- CUBS-MS (NCT05772637)
- Testing
- Repeated cystometries with bladder sensations assessment
- Where
- France
- Volunteers
- 113 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Overactive Bladder, Parkinson Disease
Behavioral and/or Mirabegron to Treat Urinary Symptoms in Parkinson Disease
The purpose of this study is to learn about different treatments for overactive bladder symptoms in Parkinson's Disease. The investigators want to find out if people who do not respond to one treatment (either behavioral or drug…
- Trial name
- SQUARE PD (NCT07187466)
- Testing
- mirabegron, Exercise-based behavioral therapy
- Where
- 3 sites in United States
- Volunteers
- 146 people
- Sponsor
- VA Office of Research and Development
Urinary Incontinence, Daytime Wetting
Brain Activity Among Children With Overactive Bladder and Daytime Urinary Incontinence and Healthy Children
The aim of this study is to investigate whether the activity in brain areas controlling the bladder is different among children suffering from Overactive Bladder (OAB) and Daytime Urinary Incontinence (DUI) compared to age- and…
- Conditions
- Urinary Incontinence, Daytime Wetting, Urination Disorders, Urination Involuntary
- Trial name
- NCT05989646
- Testing
- Sacral TENS
- Where
- 4 sites in Denmark
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Cervical Carcinoma, Endometrial Carcinoma
Flyte Device for Improving Urinary Incontinence Among Endometrial and Cervical Cancer Survivors Who Have Undergone Radiation Therapy
This clinical trial studies how well and how easy it is to use a device called Flyte in improving problems with bladder control (urinary incontinence) among endometrial and cervical cancer survivors who have undergone radiation…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Overactive Bladder, Voiding Disorders
- Trial name
- NCT07662824
- Testing
- Educational Intervention, Interview, Flyte Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Mayo Clinic
Overactive Bladder, Neurogenic Bladder
A Randomized, Placebo-controlled Trial of Nitrous Oxide During In-office Bladder Botox Injections
The goal of this clinical trial is to assess if a mix of nitrous oxide and oxygen can improve pain control during bladder Botox injections.
- Conditions
- Overactive Bladder, Neurogenic Bladder, Urge Incontinence, Pain
- Trial name
- NCT07387315
- Testing
- Pro-Nox Nitrous Oxide/Oxygen Delivery System, Standard Care for Bladder Botox Injection
- Where
- 2 sites in United States
- Volunteers
- 96 people
- Sponsor
- TriHealth Inc.
Overactive Bladder
Evaluation of Efficacy and Patient Satisfaction of Local Anaesthesia Versus Sedoanalgesia for Botox (R) Injection in the Urinary Bladder for the Treatment of Idiopathic Overactive Bladder
Patients with symptoms of overactive bladder suffer from frequent micturition, urinary incontinence and recurrent urinary tract infections.
- Trial name
- LA vs SA (NCT06437899)
- Testing
- intravesical botulinum toxin A injection unter local anaesthesia
- Where
- Austria
- Volunteers
- 84 people
- Sponsor
- Hospital LKH Hochsteiermark - Leoben
Overactive Bladder (OAB)
Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)
A study to evaluate the safety and effectiveness of FemPulse System
- Trial name
- EVANESCE-II (NCT07195656)
- Testing
- Device Group, Medication Group
- Where
- 15 sites in United States
- Volunteers
- 151 people
- Sponsor
- FemPulse Corporation
Overactive Bladder (OAB), Nocturia
A Novel Wearable Transcutaneous Tibial Nerve Stimulation (TTNS) Device in the Treatment of Patients With Overactive Bladder (OAB) and Nocturia
Overactive bladder (OAB) is a syndrome with urgency as the main symptom, usually accompanied by frequent urination, nocturia, and sometimes urge urinary incontinence.
- Trial name
- NCT07635251
- Testing
- A new wearable transcutaneous tibial nerve stimulation (TTNS) device, behavioral therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Qilu Hospital of Shandong University
Overactive Bladder (OAB), Incontinence, Urge
Efficacy and Safety of 7 Millimeters Vaginal Radiofrequency in Overactive Bladder
The investigator hypothesizes that controlled delivery of low heat (45-50 Centigrade) to the sub-detrusor and detrusor muscle can ablate the autonomic nerve endings and control overactive bladder symptoms without causing…
- Trial name
- HYPNOS (NCT07279142)
- Testing
- Radiofrequency
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS San Raffaele
Overactive Bladder (OAB), Neuromodulation
Peroneal Neuromodulation vs Pelvic Floor Exercises in OAB
Overactive bladder (OAB) is a common condition characterized by urinary urgency, usually accompanied by increased urinary frequency and nocturia, with or without urgency urinary incontinence.
- Trial name
- NCT07788560
- Testing
- Transcutaneous Peroneal Electrical Neuromodulation, Pelvic Floor Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Overactive Bladder (OAB), Urinary Urgency
Effectiveness of Ambulatory Transcutaneous Tibial Nerve Stimulation for Overactive Bladder
The goal of this clinical trial is to learn if using a portable nerve stimulation (TENS) device during daily life works to reduce overactive bladder (OAB) symptoms in adults aged 18 to 65.
- Trial name
- NCT07540273
- Testing
- Ambulatory Transcutaneous Tibial Nerve Stimulation, Conventional Clinic-Based Transcutaneous Tibial Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- SEZGIN
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
Aquarius Pilot Study to Evaluate the New Axonics Trial System
Evaluation of the new Axonics External Trial System (ETS-02) in patients with overactive bladder (OAB) and/or fecal incontinence (FI).
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Fecal Incontinence (FI), Overactive Bladder (OAB)
- Trial name
- NCT07335484
- Testing
- Axonics External Trial System (ETS)
- Where
- 5 sites in United States, Australia
- Volunteers
- 75 people
- Sponsor
- Axonics, Inc.
Spinal Cord Injuries (SCI), Detrusor Overactivity
The Effectiveness of Transcutaneous Sacral Neuromodulation Techniques-Magnetic Stimulation and Electrical Stimulation-on Detrusor Overactivity in Patients With Spinal Cord Injury
The goal of this prospective, randomized clinical trial is to compare the efficacy and safety of transcutaneous sacral magnetic stimulation versus sacral electrical stimulation for detrusor overactivity in 40 male and female…
- Trial name
- NCT07578532
- Testing
- Transcutaneous Sacral Electrical Stimulation, Transcutaneous sacral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Overactive Bladder
Predictive Utility and Mechanisms of Sacral Evoked Responses in Sacral Neuromodulation
Electrical stimulation of the sacral nerve can help with bladder problems and pelvic pain but researchers don't understand exactly how the stimulation helps.
- Trial name
- NCT06983470
- Testing
- SNM based on visual-motor responses (VMRs), SNM based on sacral evoked responses (SERs)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Overactive Bladder (OAB)
Burden and Efficacy of Anticholinergic vs Mirabegron in Overactive Bladder - A Randomized Controlled Study
Overactive bladder (OAB) is a common condition that causes a sudden, strong need to urinate, often with frequent daytime and night-time trips to the toilet, and sometimes leaking.
- Trial name
- BEAM (NCT07711808)
- Testing
- Solifencin, Mirabegron
- Volunteers
- 208 people
- Sponsor
- Universidade do Porto
Overactive Bladder (OAB)
Evaluate the Safety and Efficacy of TRG-200 KIT in Patients With Refractory Overactive Bladder.
This is an open-label, single-center pilot study designed to evaluate the safety, tolerability, and preliminary efficacy of TRG-200 KIT, an intravesical sustained-release oxybutynin formulation, in adult patients with refractory…
- Trial name
- NCT07391878
- Testing
- TRG-200 KIT
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Trigone Pharma Ltd.
Overactive Bladder (OAB), Urinary Tract Infection (Diagnosis)
Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA Injection
The goal of this clinical trial is to compare methenamine hippurate prophylaxis to routine antibiotic prophylaxis following onabotulinumtoxinA (BOTOX-A) injections in women with overactive bladder (OAB).
- Trial name
- META (NCT06953271)
- Testing
- Methenamine Hippurate, Typically prescribed oral antibiotic prophylaxis
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Bladder, Overactive, Urinary Incontinence, Urge
Treatment Efficacy for Overactive Bladder: Comparing Education, Biofeedback, and Nerve Stimulation
The purpose of this clinical trial is to evaluate the effectiveness of different behavioral therapies and neuromodulation for treating women with idiopathic Overactive Bladder (OAB).
- Trial name
- NCT07744620
- Testing
- Behavioral, Enraf-Nonius EMG-Biofeedback Unit (Biofeedback only), Enraf-Nonius EMG-Biofeedback Unit (Biofeedback + Electrical Stimulation)
- Where
- Taiwan
- Volunteers
- 201 people
- Sponsor
- Far Eastern Memorial Hospital
Overactive Bladder (OAB)
Tensi+ for Treating Overactive Bladder
The purpose of the study is to evaluate the safety and effectiveness of the Tensi+ device using Transcutaneous Posterior Tibial Nerve Stimulation (TPTNS) for treating patients suffering from OAB symptoms urinary frequency…
- Trial name
- NCT07300904
- Testing
- Tensi+
- Where
- 3 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Stimuli Technology
Urinary Incontinence, Urinary Urge Incontinence
Real-World Registry - The Vivally® System
This is a Real-World Registry Study to collect real-world dosing, utilization, demographic, quality of life, and data from the e-bladder diaries of patients utilizing the Vivally® System.
- Trial name
- NCT06085846
- Testing
- Vivally® System Wearable, Non-Invasive Neuromodulation System, and Mobile Application
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Avation Medical, Inc.