Clinical trials: Urinary Calculi
Renal Calculi, Kidney Stones
Clinical Evaluation of BackStop in Patients Undergoing Intraureteric Stone Lithotripsy
The purpose of this clinical study is to evaluate BackStop, a polymer-based device that is intended to be used during ureteroscopic lithotripsy to prevent retrograde stone migration.
- Trial name
- NCT00893282
- Testing
- BackStop, Intracorporeal lithotripsy without the use of an anti-retropulsion device
- Where
- Canada
- Volunteers
- 68 people
- Sponsor
- Pluromed, Inc.
Urinary Stone
2D:4D Digit Ratio and Urinary Stone Disease
This prospective observational case-control study will investigate whether the 2D:4D digit ratio is associated with urinary stone disease.
- Trial name
- NCT07736924
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Emrah Kızılay
Kidney Stones
FANS-Assisted Mini-PCNL for Complex Renal Stones
This prospective pilot study aims to evaluate the feasibility, safety, and preliminary clinical outcomes of a novel mini-percutaneous nephrolithotomy (mini-PCNL) technique integrating a flexible mini-nephroscope with a flexible…
- Trial name
- FANS-MiniPerc (NCT07332286)
- Testing
- FANS-assisted mini-percutaneous nephrolithotomy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Stone, Kidney, Urolithiasis
Staged Bilateral Percutaneous Nephrolithotomy
To determine the optimal time between the first and second operations in patients with bilateral kidney stones and scheduled percutaneous nephrolithotomy for the contralateral kidney.
- Trial name
- NCT05340075
- Testing
- Patients who underwent percutaneous nephrolithotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara Training and Research Hospital
Kidney Calculi
Apply Machine Learning to the Interpretation of Urinary Crystal Morphology.
The goal of this observational study is to developing an image-based artificial intelligence software that can automatically interpret the types and sizes of crystals in urine.
- Trial name
- NCT06178575
- Volunteers
- 200 people
- Sponsor
- Yi-Shiou Tseng
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Urinary Tract Stone
Effectiveness of WhatsApp Education and Support Messages for Urolithiasis Prevention
Kidney and ureteral stones are a common problem in primary care practice with increasing prevalence over the last few decades. Prevention of recurrent stones (which are usually composed primarily of calcium oxalate) is aimed at…
- Trial name
- StoneApp (NCT05627622)
- Testing
- WhatsApp health education message
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Hyperuricemia, Gout
Effect of Quercetin Supplements on Healthy Males: a Four-Week Randomized Cross-Over Trial
The purpose of this study was to test the effect of chronic consumption of Quercetin 500 mg tablets on blood uric acid and other biomarkers in adult males.
- Conditions
- Hyperuricemia, Gout, Kidney Calculi, Diabetes
- Trial name
- NCT01881919
- Testing
- Treatment, Control
- Where
- United Kingdom
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Kidney Stones, Complex Renal Calculi
Modified Mini-PCNL Versus Standard PCNL for Complex Kidney Stones
Kidney stones that are large or complex are often treated with percutaneous nephrolithotomy, also called PCNL. Standard PCNL uses a larger access tract and is effective for removing complex kidney stones, but it may be associated…
- Trial name
- MIMIC-PCNL (NCT07697677)
- Testing
- 20 Fr Modified Mini Percutaneous Nephrolithotomy, 24 Fr Standard Percutaneous Nephrolithotomy
- Where
- China
- Volunteers
- 1,380 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urolithiasis
Renal Stone Treatment Global Registry
This is an international prospective data registry to assess the treatment outcomes and complications of different treatment approaches for different surgical treatment of urolithiasis.
- Trial name
- NCT05297331
- Where
- 3 sites in Hong Kong
- Volunteers
- 3,000 people
- Sponsor
- Chinese University of Hong Kong
Kidney Stone, Ureteral Stone
Thulium Fiber Laser vs. Holmium:YAG Laser for the Ureteroscopic Treatment of Patients With Urinary Stone Disease
This is a randomized controlled trial which aims to compare the efficacy and safety of Thulium fiber laser (TFL) and holmium:yttrium-aluminum-garnet (Ho:YAG) laser ablation during the treatment of upper urinary tract stone…
- Trial name
- NCT06306222
- Testing
- Laser lithotripsy
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- IRCCS San Raffaele
Kidney Stones, Urolithiasis
Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic Urolithiasis
Recent investigations from this group have identified that genetic variants of genes associated with monogenic forms of nephrolithiasis are expressed in idiopathic calcium oxalate kidney stone patients and could influence stone…
- Conditions
- Kidney Stones, Urolithiasis, Calcium Oxalate Urolithiasis
- Trial name
- NCT01127854
- Where
- United States
- Volunteers
- 2,900 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Healthy
Renal Metabolism of Glycolate to Oxalate
This study will determine the contribution of glycolate metabolism to urinary oxalate excretion in healthy subjects, using carbon 13 isotope glycolate tracer technique and a low-oxalate controlled diet.
- Trial name
- NCT04437225
- Testing
- Low oxalate controlled Diet, Primed, continuous intravenous infusion of 13C2-Glycolate, Bolus intravenous infusion of 13C2-Glycolate
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Renal Calculi
Suctioning Flexible Ureteroscopy With Intelligent Control of Renal Pelvic Pressure
This study evaluates the safety and efficacy of the suctioning flexible ureteroscopy(SF-URS) with automatic control of renal pelvic pressure for the treatment of upper urinary calculi using a prospective, randomized design.
- Trial name
- NCT02734914
- Testing
- SF-URS with automatic control of RPP, conventional F-URS
- Volunteers
- 60 people
- Sponsor
- The Affiliated Ganzhou Hospital of Nanchang University
Urinary Calculi, Emergency Service, Hospital
Analysis the Relationship Between the Abdomen CT and Outcomes in Acute Urinary Stone Patients
This is an observational study based on retrospectively collected data of ureter stone patients between 2011 and 2014. Aim of study is to determine radiologic findings of non-contrast abdominal computerized tomography as…
- Trial name
- NCT02983409
- Testing
- Pstone
- Volunteers
- 862 people
- Sponsor
- Konkuk University Medical Center
Urinary Tract Stones
Multicenter Study to Develop a Model to Identify Uric Acid Urinary Tract Stones Using CT and Lab Tests
Urinary tract stones are a common condition affecting the kidney, ureter, bladder, and urethra. Uric acid stones represent an important subtype of urinary stones and require different prevention and treatment strategies compared…
- Trial name
- UAS-Model (NCT07328932)
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 1,650 people
- Sponsor
- Jian Zhuo
Urinary Tract Infections, Urinary Stone
Urine pH and Urinary Tract Infection
Urinary tract infections (UTI) affect the urine pH and may lead to salt precipitation such as struvite. Bacteria with urease activity are known to alkalinise urine, but not much is known on how pH is changing over time during…
- Trial name
- PHURINE (NCT04598971)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Kidney Stone, Ureteric Stone
Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg
Ureteral stenting is a common urological procedure performed to relieve obstruction and facilitate urinary drainage. Despite its effectiveness, stent-related symptoms (SRS) such as dysuria, frequency, urgency, flank pain, and…
- Trial name
- NCT07562282
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Urolithiasis, Stones, Kidney
Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence Study
The goal of this clinical trial is to evaluate the effectiveness and safety of Steerable Ureteroscopic Renal Evacuation (SURE) with the CVAC System versus other commonly used renal-stone interventions.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- SCORE (NCT07155005)
- Testing
- CVAC® SYSTEM, FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS), DIRECT IN-SCOPE SUCTION (DISS) IN FLEXIBLE URETEROSCOPY (FURS)
- Volunteers
- 1,000 people
- Sponsor
- Calyxo, Inc.
Nephrolithotomy, Percutaneous, Kidney Stone
The Newly Reported (0-90°) Versus (0-30°) Biplanar Fluoroscopic Puncture Technique in PCNL
To analyze and compare the puncture success rate, puncture fluoroscopy time and intraoperative puncture complications of two different puncture techniques; fluoroscopic bi-planar (0-30º) versus newly reported bi-planar (0-90º)…
- Conditions
- Nephrolithotomy, Percutaneous, Kidney Stone, PCNL
- Trial name
- NCT04557722
- Testing
- 0-30° Biplanar Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy, New 0-90° Fluoroscopic Puncture Techniques for Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University