Clinical trials: Urinary Complications
Urinary Incontinence, Stress
A 3 Years Naturalistic Cohort Survey Of Virtue® Male Sling System For Male Stress Urinary Incontinence
The purpose of this study is to monitor the use of Virtue® Male Sling in a real world population and collect medical data on effectiveness and to monitor safety of Virtue® at 12 and 36 months post device implantation in men with…
- Trial name
- NCT04098822
- Testing
- Virtue male sling
- Where
- 13 sites in France, Italy
- Volunteers
- 130 people
- Sponsor
- Coloplast A/S
Bladder Cancer
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) and Pembrolizumab (MK-3475A) in Participants With Bladder Cancer (MK-2870-055)
Researchers are looking for new ways to treat muscle-invasive bladder cancer (MIBC). MIBC is a type of bladder cancer that has spread into the muscle layer of the bladder but has not spread to other distant parts of the body.
- Trial name
- TroFuse-055 (NCT07829783)
- Testing
- Sac-TMT, Pembrolizumab and Berahyaluronidase alfa, Cisplatin
- Volunteers
- 400 people
- Sponsor
- Merck Sharp & Dohme LLC
Metastatic Urothelial Cancer
Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer (Duravelo-2)
This is a global, multicenter, randomized, open-label study. The main objective of the study is to measure the clinical activity and safety of zelenectide pevedotin formally BT8009, in combination with pembrolizumab versus…
- Trial name
- NCT06225596
- Testing
- Zelenectide pevedotin, Pembrolizumab, Gemcitabine + cisplatin Or carboplatin
- Where
- 102 sites in United States, Argentina and 19 more
- Volunteers
- 375 people
- Sponsor
- BicycleTx Limited
Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax
Special Drug Use Investigation of Ciproxan Injection in Pediatrics
The objective in this study is collecting post-marketing information on the safety and efficacy of Ciproxan injection under the routine clinical practice.
- Trial name
- NCT02555059
- Testing
- Cipro (Ciprofloxacin, BAYQ3939)
- Where
- Japan
- Volunteers
- 48 people
- Sponsor
- Bayer
Urinary Incontinence
An Exploratory Investigation of the Effects of Single Use vs. Reuse Catheters in Intermittent Catheterization
The overall aim of the investigation is to investigate the effect of repeated reuse of intermittent urinary catheters and to observe the impact of switch from single use to multiple reuse catheters.
- Trial name
- NCT05626686
- Testing
- CLINY catheter
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Coloplast A/S
Urothelial Cancer
Study of Pembrolizumab (MK-3475) in Participants With Advanced Urothelial Cancer (MK-3475-052/KEYNOTE-052)
This is a study using pembrolizumab (MK-3475, KEYTRUDA®) for first-line treatment of participants with advanced/unresectable (inoperable) or metastatic urothelial cancer who are ineligible for cisplatin-based therapy.
- Trial name
- NCT02335424
- Testing
- pembrolizumab
- Volunteers
- 374 people
- Sponsor
- Merck Sharp & Dohme LLC
Overactive Bladder
Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine for Overactive Bladder (OAB)
To evaluate the efficacy and safety of fesoterodine in comparison to tolterodine and placebo for overactive bladder
- Trial name
- NCT00444925
- Testing
- fesoterodine fumarate, tolterodine tartrate
- Where
- 178 sites in United States, Belgium and 27 more
- Volunteers
- 1,712 people
- Sponsor
- Pfizer
Overactive Bladder (OAB)
A Study to Evaluate Tolerability and Participants Preference Between Mirabegron and Tolterodine Extended Release (ER) in Participants With Overactive Bladder (OAB)
The purpose of this study was to assess tolerability of mirabegron compared to tolterodine ER in the treatment of participants with symptoms of Overactive Bladder (OAB) as well as the impact of treatment on micturition frequency…
- Trial name
- PREFER (NCT02138747)
- Testing
- Mirabegron, Tolterodine ER
- Where
- 30 sites in United States, Canada
- Volunteers
- 376 people
- Sponsor
- Astellas Pharma Global Development, Inc.
Bladder Cancer
Incontinent Urinary Diversion Using an Autologous Neo-Urinary Conduit
The purpose of this study is to see if the Neo-Urinary Conduit(NUC), which is made in the laboratory from a combination of a patient's own cells and other materials can be used to form a conduit to safety allow urine flow from…
- Trial name
- NCT01087697
- Testing
- Neo-Urinary Conduit
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Tengion
Urothelial Carcinoma of the Urinary Bladder
A Phase 1 Study of Intravesical VAX014 for Instillation in Subjects With Non-Muscle Invasive Bladder Cancer
The purpose of this research study is to evaluate the safety, tolerability and activity of VAX014 for Instillation (VAX014) in patients with low-grade Non-Muscle Invasive Bladder Cancer (NMIBC).
- Trial name
- NCT03854721
- Testing
- VAX014
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- Vaxiion Therapeutics
Recurrent Urinary Tract Infection
Nutritional Supplementation for Recurrent Urinary Tract Infections in Women
The study will test the ability of specially formulated nutritional supplement capsules to extend the time between recurrent urinary tract infections in women.
- Trial name
- NCT03597152
- Testing
- WelTract
- Volunteers
- 250 people
- Sponsor
- AmPurity Nutraceuticals, LLC
Advanced Solid Tumor, Metastatic Cancer
Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer
This is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007, also known as imneskibart, in patients with advanced solid tumors.
- Conditions
- Advanced Solid Tumor, Metastatic Cancer, Cutaneous Melanoma, Non-Small Cell Lung Cancer
- Trial name
- NCT05267626
- Testing
- AU-007, Aldesleukin, Avelumab
- Where
- 17 sites in United States, Australia
- Volunteers
- 159 people
- Sponsor
- Aulos Bioscience, Inc.
Urinary Incontinence, Stress
An 8 Week Study Looking At The Efficacy, Toleration And Safety Of SS-RBX For Stress Urinary Incontinence.
A study designed to assess the efficacy, toleration and safety of SS-RBX for the treatment of stress urinary incontinence.
- Trial name
- NCT00138749
- Testing
- SS-RBX
- Where
- 95 sites in United States, Canada
- Volunteers
- 402 people
- Sponsor
- Pfizer
Stress Urinary Incontinence
A Clinical Evaluation of the Tension-Free Vaginal Tape Obturator System For Treatment of Stress Urinary Incontinence (Urinary Leakage)
Stress urinary incontinence affects nearly 30 million women worldwide and the main goal of surgical treatment is to stop urinary incontinence (urinary leakage) that occurs with physical activity, coughing, sneezing, etc.Patients…
- Trial name
- NCT00196521
- Testing
- Tension-free vaginal tape obturator system
- Where
- 19 sites in United States, Canada and 5 more
- Volunteers
- 300 people
- Sponsor
- Ethicon, Inc.
Prostatic Neoplasms, Multiple Myeloma
Safety and Pharmacokinetics of Orally Administered Gallium Maltolate in Various Refractory Malignancies
This study will test the safety, tolerance, and efficacy of different doses of oral gallium maltolate. Patients will receive oral gallium maltolate twice daily for 28-consecutive days followed by 14 days off treatment.
- Conditions
- Prostatic Neoplasms, Multiple Myeloma, Bladder Neoplasms, Lymphoma
- Trial name
- NCT00050687
- Testing
- Gallium maltolate
- Where
- 5 sites in United States
- Sponsor
- Titan Pharmaceuticals
Overactive Bladder
A Clinical Study for Magnetic Stimulation of the Posterior Tibial Nerve in Overactive Bladder
To evaluate the safety and feasibility of non-invasive magnetic stimulation of the posterior tibial nerve using the EMKinetics LoFIT Pulse System for treating patients with documented overactive bladder.
- Trial name
- NCT01214265
- Testing
- EMKinetics non-invasive Magnetic neurostimulator
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- EMKinetics, Inc
Bladder Cancer
A Randomized, Comparative Study of Hexvix Fluorescence Cystoscopy and Standard Cystoscopy in Patients With Non-invasive Bladder Cancer
The main objective of the study is to compare the 1-year recurrence rate of Hexvix assisted Transuretheral Resection of the Bladder (TURB) to standard white light TURB in patients with suspicion of non-invasive bladder cancer.
- Trial name
- NCT00412971
- Testing
- Hexvix, Standard white light cystoscopy
- Where
- 2 sites in Denmark
- Volunteers
- 233 people
- Sponsor
- Photocure
Overactive Bladder
Autologous Neo-Bladder Construct in Non-Neurogenic Overactive Bladder and Urge Predominant Incontinence
Subjects with non-neurogenic over-active bladder will be enrolled. The hypothesis is that augmentation cystoplasty using an autologous neo-bladder construct will increase functional capacity and thereby reduce the number of…
- Trial name
- NCT00594139
- Testing
- Autologous neobladder construct
- Where
- United States
- Sponsor
- Tengion
Carcinoma, Transitional Cell
Tesetaxel for Previously Treated Patients With Bladder Cancer
The intravenously administered taxanes, docetaxel and paclitaxel, alone and in combination with other chemotherapy agents are active in patients with advanced and metastatic bladder cancer, and agents of this class are a…
- Trial name
- NCT01215877
- Testing
- Tesetaxel
- Where
- 3 sites in United States, Italy
- Volunteers
- 33 people
- Sponsor
- Genta Incorporated
Overactive Bladder
A Study to Examine the Safety and Efficacy of a New Drug in Patients With Symptoms of Overactive Bladder (OAB)
This study is designed to evaluate the safety, tolerability, and efficacy of vibegron administered once daily in patients with OAB.
- Trial name
- Empowur (NCT03492281)
- Testing
- vibegron, Tolterodine Tartrate ER
- Where
- 215 sites in United States, Canada and 4 more
- Volunteers
- 1,530 people
- Sponsor
- Urovant Sciences GmbH
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.