Clinical trials: Urinary Dysfunction, open to volunteers
Stress Urinary Incontinence, Female Urinary Incontinence
Effect of Modified Mesh on Surgical Success in Transobturator Tape Surgery
This study is a single-blind, randomized controlled trial evaluating whether changing the width of the surgical tape (mesh) used in transobturator tape (TOT) surgery improves treatment results in women with stress urinary…
- Conditions
- Stress Urinary Incontinence, Female Urinary Incontinence, Pelvic Floor Dysfunction
- Trial name
- MOTOT (NCT06924450)
- Testing
- 1.2 cm Mesh TOT, 1.0 cm Mesh TOT
- Where
- Turkey (Türkiye)
- Volunteers
- 106 people
- Sponsor
- Izzet Celegen
Patients Admitted to the ICU, Expected Hospital Stay ≥48 Hours
Enterocyte Injury and Acute Gastrointestinal Dysfunction in Critical Illness
Acute gastrointestinal injury (AGI) is a common but not fully understood organ dysfunction in critically ill patients. Current AGI grading systems rely primarily on clinical presentation and feeding tolerance, which are…
- Conditions
- Patients Admitted to the ICU, Expected Hospital Stay ≥48 Hours, Adult
- Trial name
- NCT07440368
- Testing
- Plasma and urine I-FABP measurement
- Volunteers
- 500 people
- Sponsor
- The First Hospital of Jilin University
Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer
Multimodal Prehabilitation and Rehabilitation for Men Undergoing Robot-Assisted Radical Prostatectomy
Prostate cancer is the most common cancer in Australian men. Robot-assisted radical prostatectomy (RARP) - surgical removal of the prostate - is a standard treatment, but it frequently causes erectile dysfunction (ED) and urinary…
- Conditions
- Erectile Dysfunction Following Radical Prostatectomy, Prostate Cancer, Urinary Incontinence Following Surgical Procedure
- Trial name
- ROBOPREP (NCT07576335)
- Testing
- Tadalafil 5 mg, Pelvic Floor Muscle Training (PFMT), Aerobic Exercise Program
- Where
- 3 sites in Australia
- Volunteers
- 64 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy
This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- MPE-RP (NCT07520916)
- Testing
- Mobile-Based Perioperative Education Program, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Giresun University
Survivors of Childhood Cancer, Bladder Dysfunction
Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children
The over-arching aim of this study is to evaluate the effects of two specific anti-cancer chemotherapies, vincristine and doxorubicin, on bladder function and urine composition.
- Trial name
- NCT04993859
- Testing
- Non-invasive Urodynamic Test (niUDS), Urinary proteomic screen, Dysfunctional Voiding Symptom Score Survey (DVSS)
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Colorado, Denver
Osteoporosis, Postmenopausal
Stress Urinary Incontinence and Sarcopenia in Postmenopausal Osteoporosis
The primary aim of our study is to evaluate the presence of stress urinary incontinence in postmenopausal patients with and without osteoporosis, determine its impact on quality of life, and explore its relationship with…
- Trial name
- NCT06655701
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Pelvic Prolapse Conditions
Barriers and Enablers to Accessing Medical Care for Urinary Incontinence and Prolapse in GLobal Majority Women
This project aims to explore barriers to treatment seeking for symptoms of prolapse and urinary incontinence in women from ethnic minority/global majority background.
- Trial name
- BEAM UP & GLOW (NCT07310121)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Prostate Cancer
IONM During Radical Prostatectomy
At present, the preferred treatment for patients with prostate cancer is still radical prostatectomy. Postoperative patients often face some complications, the most common complications include urinary incontinence and erectile…
- Trial name
- NCT06950216
- Testing
- IONM
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Urinary Tract Disease
Antibiotic Strategy and Asymptomatic Bacteriuria in the Context of Intra-vesical Botulinum Toxin A Injections.
The study aims to demonstrate that the "thrifty antibiotic strategy" applied to MS or SCI patients with asymptomatic bacteriuria prior to BoNTA intravesical injections does not increase the rate of symptomatic post-injection UTIs…
- Trial name
- ANTIBIOBONTA (NCT05534399)
- Testing
- Intra-vesical BoNTA injections
- Where
- France
- Volunteers
- 526 people
- Sponsor
- University Hospital, Lille
Voiding Dysfunction, Urinary Incontinence
Prevalence of Functional Lower Urinary Tract Voiding Dysfunction in School-Aged Children
The aim of this study is to investigate the prevalence of voiding disorders and the related risk factors for the primary school-age children in El Ghrbia Government
- Conditions
- Voiding Dysfunction, Urinary Incontinence, Urination Disorders, Lower Urinary Tract Symptoms
- Trial name
- NCT07067957
- Testing
- Arabic Dysfunctional Voiding Symptom Score Questionnaire (DVSS)
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Tanta University
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)
UCon is a medical device for treatment of the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behaviour of the bladder/bowel musculature…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Fecal Incontinence, Fecal Incontinence With Fecal Urgency
- Trial name
- NCT06091566
- Testing
- UCon-Bar
- Where
- 3 sites in Denmark
- Volunteers
- 20 people
- Sponsor
- InnoCon Medical
Bladder Pain Syndrome, Female Sexual Dysfunction
Effect of Intradetrusor onabotulinumtoxinA Injection Versus Conservative Management on Female Sexual Function in Patients With Bladder Pain Syndrome
Interstitial cystitis/bladder pain syndrome (IC/BPS) is estimated to affect 3.3 to 7.9 million women aged 18 years and older in the United States.
- Trial name
- NCT06729151
- Testing
- Onabotulinum toxin A, Conservative management (dietary and behavioral)
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia (BPH)
Uroflowmetry Curve Types and IPSS in Men With LUTS
This prospective observational study aims to evaluate the relationship between different uroflowmetry curve types and International Prostate Symptom Score (IPSS) domains in men presenting with lower urinary tract symptoms (LUTS).
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia (BPH), Voiding Dysfunction
- Trial name
- UROFLOW-IPSS (NCT07016776)
- Volunteers
- 250 people
- Sponsor
- Tarik Emre Sener
Diastasis Recti, Diastasis Recti Abdominis (DRA)
Effects of Visceral Manipulation Combined with Kinesio Taping on Diastasis Recti, Pain Intensity, Stress Incontinence, Pelvic Floor Strength, and Overall Wellness in Postpartum Women
This clinical trial aims to evaluate the effectiveness of different therapies for treating Diastasis Recti Abdominis (DRA) in postpartum women.
- Trial name
- NCT06723353
- Testing
- Visceral Manipulation Therapy, Abdominal Kinesio Taping, Combined Visceral Manipulation and Kinesio Taping
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- Health and Research-Insights
Cerebellar Ataxia, Neuropathy
Evaluation of Urinary Dysfunction in CANVAS Patients
The investigator wishes to evaluate the prevalence of urinary symptoms in patients diagnosed with Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS).
- Conditions
- Cerebellar Ataxia, Neuropathy, Vestibular Areflexia
- Trial name
- UROCANVAS (NCT06817707)
- Testing
- Evaluation of urinary dysfunction in patients with CANVAS
- Where
- 3 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Spinal Cord Injury
Cold vs. Paraspinal Stimulation for Erectile and Urinary Function in SCI Patients
This study is being conducted to compare the effects of two simple treatments-cold therapy and electrical stimulation applied to the lower back-on sexual function and urinary control in men with spinal cord injury (SCI).
- Trial name
- NCT07101042
- Testing
- Cold Stimulation, Paraspinal Electrical Stimulation
- Volunteers
- 30 people
- Sponsor
- Cairo University
Neurogenic Bladder, Diseases of the Lower Urinary Tract: General Conditions
Lower Urinary Tract Dysfunction Database
Patients with neurological disease/injury often suffer from lower urinary tract symptoms, which frequently have a negative impact on the patients' health related quality of life.
- Trial name
- NCT01293110
- Where
- Switzerland
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Lower Urinary Tract Symptom, Benign Prostate Obstruction (BPO)
Uroflowmetry and IPSS Factors Influencing Surgical Decision
This study aims to identify which symptoms or test findings lead men with lower urinary tract symptoms (LUTS) to consider surgical treatment.
- Conditions
- Lower Urinary Tract Symptom, Benign Prostate Obstruction (BPO), Voiding Dysfunction
- Trial name
- NCT07047599
- Volunteers
- 100 people
- Sponsor
- Marmara University
Participants With Underactive Bladder (UAB)
A Proof-Of-Concept (POC) Study of SFG-02 Transdermal Formulation in Participants With Underactive Bladder (UAB)
The objective of this POC (Phase 2a) study is to evaluate the effect on Bladder Voiding Efficiency (BVE) as well as safety of SFG-02 transdermal formulation in participants with UAB.
- Trial name
- NCT07906106
- Testing
- SFG-02
- Where
- 16 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Juro Sciences Inc.
Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom
Clinical Outcomes and Ejaculatory Function in BPO Patients Treated With Silodosin
This observational study aims to evaluate the relationship between silodosin-induced anejaculation and clinical outcomes in male patients with benign prostatic obstruction (BPO).
- Conditions
- Benign Prostate Obstruction (BPO), Lower Urinary Tract Symptom, Ejaculatory Dysfunction, Anejaculation
- Trial name
- NCT06989515
- Volunteers
- 100 people
- Sponsor
- Marmara University