Clinical trials: Urinary Incontinence, Urge
Pain, Chronic, Urge Incontinence
Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a collective term referring to disorders which is characterized by lower urinary tract symptoms, including bladder pain/discomfort, frequent urination without evidence of…
- Conditions
- Pain, Chronic, Urge Incontinence, Overactive Bladder Syndrome, Quality of Life
- Trial name
- VARIC (NCT05094414)
- Testing
- Valacyclovir
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Urinary Incontinence
Athena Pelvic Muscle Trainer - DUETS Trial
The purpose of this study is to determine if the Athena Pelvic Muscle Trainer device effectively treats stress, urge or mixed incontinence in women by strengthening the pelvic floor muscles by collecting data from the patient on…
- Trial name
- DUETS (NCT01073878)
- Testing
- Athena Pelvic Muscle Trainer
- Where
- 97 sites in United States, Virgin Islands
- Volunteers
- 462 people
- Sponsor
- Athena Feminine Technologies, Inc.
Urge Urinary Incontinence
The Long Term Outcomes of Rehabilitation and Drug Treatment for in Urgency Urinary Incontinence
Urinary Urge Incontinence (UUI) is the involuntary urine loss associated with a strong sensation to void. UUI usually associated with reduced bladder capacity. The pathophysiology is unclear.
- Trial name
- UUI (NCT00498888)
- Testing
- tolterodine, bladder training, pelvic floor muscle training
- Where
- Israel
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
Urinary Incontinence
A Study to Evaluate the Safety and Efficacy of OROS® Oxybutynin Chloride for the Treatment of Urge Urinary Incontinence
The purpose of this study is to is to evaluate the safety and efficacy of OROS® oxybutynin chloride in patients being treated for urge urinary incontinence.
- Trial name
- NCT00269724
- Testing
- OROS® oxybutynin
- Volunteers
- 250 people
- Sponsor
- Alza Corporation, DE, USA
Overactive Bladder Syndrome, Urinary Urge Incontinence
Cycling Study With the Axonics System
A prospective, multi-center, study comparing continuous sacral neuromodulation (SNM) stimulation to daily cyclic stimulation of 2 hours "on" and 22 hours "off" using the Axonics System.
- Conditions
- Overactive Bladder Syndrome, Urinary Urge Incontinence, Sacral Neuromodulation
- Trial name
- NCT05543382
- Testing
- Axonics System
- Where
- 6 sites in United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Axonics, Inc.
Obesity, Primary, Incontinence, Urge
The Effect of Incontinence Program Applied to Obese Elderly on Quality of Life, Coping and Loneliness
The goal of this: It was planned in a single-blind randomized controlled pre-test-post-test experimental research design. The aim of this study is to determine the effect of urinary incontinence management program on quality of…
- Conditions
- Obesity, Primary, Incontinence, Urge, Incontinence Stress, Aging
- Trial name
- NCT05892575
- Testing
- improving quality of life, coping with urinary incontinence and kegel exercise training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Urinary Urge Incontinence (UUI), Urinary Frequency (UF)
PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB
Post-market clinical follow-up for continued assessment of safety and performance to confirm long-term outcomes of the Axonics SNM System INS Model 5101.
- Conditions
- Urinary Urge Incontinence (UUI), Urinary Frequency (UF), Overactive Bladder (OAB)
- Trial name
- NCT06789406
- Testing
- Axonics SNM System INS Model 5101 (R20)
- Where
- 6 sites in United States, United Kingdom
- Volunteers
- 55 people
- Sponsor
- Axonics, Inc.
Female Stress Urinary Incontinence, Mixed Incontinence, Urge and Stress
Er:YAG Laser Treatment for Female Stress and Mixed Urinary Incontinence (IncontiLase)
The purpose of this study was to evaluate the effect of a non-invasive Er:YAG thermal laser therapy in treating female stress and mixed urinary incontinence.
- Trial name
- NCT02418299
- Testing
- IncontiLase Er:YAG laser treatment
- Volunteers
- 175 people
- Sponsor
- Juna d.o.o.
Lower Urinary Tract Symptoms, Female Genitourinary Disease
Efficacy of Vaginal 17β-Estradiol on the Urinary Storage Symptoms in Postmenopausal Women
The goal of this clinical trial is to evaluate whether vaginal 17β-estradiol effectively treats storage symptoms of lower urinary tract symptoms (LUTS) and enhances quality of life.
- Conditions
- Lower Urinary Tract Symptoms, Female Genitourinary Disease, Urinary Stress Incontinence, Urinary Urge Incontinence
- Trial name
- NCT06508944
- Testing
- vaginal 17 beta-estradiol, Behavioral modifications
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Mahidol University
Urge Urinary Incontinence
COMPARATIVE EFFICACY OF ELECTROMAGNETIC FIELD THERAPY AND TIBIAL NERVE STIMULATION IN URGE URINARY INCONTINENCE
Urge urinary incontinence is a prevalent condition characterized by involuntary leakage of urine accompanied by a sudden, compelling urge to void.
- Trial name
- NCT07536139
- Testing
- Magnetic Field Therapy (PEMF), Posterior Tibial Nerve Stimulation (PTNS), Pelvic Floor Muscle Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Urge Incontinence, Overactive Bladder
A Study of Transcutaneous Electrical Nerve Stimulation for Overactive Bladder
The purpose of the study is to compare patient centered- outcomes between Transcutaneous Electrical Nerve Stimulation (TENS) at three locations to treat urinary urge incontinence.
- Trial name
- NCT02922842
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urinary Incontinence, Urinary Incontinence, Urge
Safety and Performance of UCon Patch Electrode
UCon is a medical device for treating the symptoms of overactive bladder (OAB) and bowel dysfunction (BD). It electrically stimulates the DGN through the skin to obtain modulated behavior of the bladder/bowel musculature e.g.…
- Conditions
- Urinary Incontinence, Urinary Incontinence, Urge, Nocturia, Urinary Frequency More Than Once at Night
- Trial name
- NCT06754189
- Testing
- Time Limited stimulation
- Where
- 3 sites in Denmark
- Volunteers
- 180 people
- Sponsor
- InnoCon Medical
Fecal Incontinence, Anal; Sphincter, Incontinence
Severity of Fecal Incontinence and Manometric Values Using the Anopress® Device in Women
The purpose of this study is to stablish a correlation between fecal incontinence severity scales (Wexner \& St. Mark's) and manometric values obtained using the Anopress® portable manometry and values obtained using endoanal…
- Conditions
- Fecal Incontinence, Anal; Sphincter, Incontinence, Incontinence, Urge
- Trial name
- MANOPRESS (NCT05058326)
- Testing
- Portable endoanal manometry, Endoanal ultrasound, Incontinence severity scale questionaires
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Urinary Urge Incontinence
Bilateral Sacrospinous Colposuspension (BSC) in the Female Genital Prolapse With Urinary Urge Symptomatology
Prospective non-randomised trial investigating the effect of vaginal vault Suspension on urge symptomatology in female patients with pelvic organ prolapse
- Trial name
- NCT03640364
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Helios Medical Center Schleswig
Urge Urinary Incontinence
A Comparison of Electrical Pudendal Nerve Stimulation and Transvaginal Electrical Stimulation for Urge Incontinence
The purpose of this study is to determine whether electrical pudendal nerve stimulation is more effective than transvaginal electrical stimulation in treating urge urinary incontinence (UUI).
- Trial name
- NCT02311634
- Testing
- Electrical pudendal nerve stimulation, Transvaginal ES
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Institute of Acupuncture, Moxibustion and Meridian
Overactive Bladder
MILADY: A Randomized, Placebo-controlled Safety and Efficacy Trial of SSR240600C in Treatment of Overactive Bladder or Urge Urinary Incontinence.
To evaluate the safety and efficacy of SSR240600C versus placebo on clinical and cystometric parameters in patients with OAB and UUI.
- Trial name
- NCT00174798
- Testing
- SSR240600C, Tolterodine
- Where
- 22 sites in United States
- Volunteers
- 118 people
- Sponsor
- Sanofi
Overactive Bladder, Urge Incontinence
Treatment of Overactive Bladder With a Digital Conversational Agent: the MOTIVATION Study
This is a proof of concept study for a digital therapeutic designed to provide first-line behavioral modification therapy for overactive bladder.
- Conditions
- Overactive Bladder, Urge Incontinence, Pelvic Floor Disorders
- Trial name
- MOTIVATION (NCT04853849)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Renalis
Overactive Bladder (OAB), Urinary Urgency
APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women
The APPROVE trial is a multi-centered, randomized controlled trial designed to assess differences in symptom improvement, quality of life, bladder symptoms, satisfaction with treatment and continued treatment efficacy in women…
- Conditions
- Overactive Bladder (OAB), Urinary Urgency, Urinary Urge Incontinence (UUI), Nocturia
- Trial name
- APPROVE (NCT06797245)
- Testing
- RiSolve App, AUGS Patient Handouts
- Where
- 10 sites in United States
- Volunteers
- 596 people
- Sponsor
- Medstar Health Research Institute
Overactive Bladder
A Confirmatory Study of KUC-7483 in Patients With Overactive Bladder
To evaluate the efficacy and the safety of KUC-7483 in overactive bladder patients.
- Trial name
- NCT01004315
- Testing
- KUC-7483, Tolterodine
- Where
- Japan
- Volunteers
- 750 people
- Sponsor
- Kissei Pharmaceutical Co., Ltd.
Incontinence Stress, Incontinence, Urge
Long-term Outcomes of Urethral and Uterosacral Ligament Plication
The aim of this study is to determine the long-term success and outcomes of urethral ligament plication surgeries in patients with stress incontinence and uterosacral ligament plication surgeries in patients with urge…
- Trial name
- ULP-USL (NCT07384117)
- Testing
- uterosacral ligament plication, urethral ligament plication
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Alev Esercan