Clinical trials: Urinary Infection
Urinary Tract Infections
Factorial Trial of Antimicrobial Therapy and/or Catheter Change for Catheter Urinary Tract Infections.
Urinary tract infection (UTI) is a common infection in patients in the intensive care unit (ICU) that increases length of stay but not mortality. It is not known whether antibiotic treatment will alter outcomes.
- Trial name
- CAUTION (NCT00795470)
- Testing
- Antimicrobial, Catheter change
- Where
- Canada
- Sponsor
- Unity Health Toronto
Recurrent UTIs, Recurrent Urinary Tract Infections
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.
- Conditions
- Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection
- Trial name
- DmannoseRCT (NCT06940622)
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Tract Infection
Evaluation of Surface Acoustics Ultrasound Device for the Treatment of Patients With Percutaneous Nephrostomy Catheters
Catheter associated urinary tract infection is one of the most common types of catheter acquired infections and adds greatly to patient morbidity, mortality and medical cost.
- Trial name
- NV-US-04-001 (NCT00702286)
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Assaf-Harofeh Medical Center
Urologic Diseases, Urinary Tract Disease
Does Antibiotic Prophylaxis at Urinary Catheter Removal Prevent Urinary Tract Infections
At the end of most urological procedures, the doctor inserts a urethral catheter for a period of up to 5 days. According to AUA's guidelines, prophylactic antibiotic is indicated during catheter removal.
- Trial name
- NCT05577273
- Testing
- Cefuroxime axetil (trimethoprim/sulfamethoxazole if penicillin allergy)
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Omri Schwarztuch Gildor
Pneumonia, Bloodstream Infection
Clinical Outcomes in Patients With Infection by Resistant Microorganism
The goal of this individual patient data meta-analysis is to estimate the attributed and the associated health burden related to bloodstream infections, pneumonia, skin and soft tissue infections, surgical site infections and…
- Conditions
- Pneumonia, Bloodstream Infection, Urinary Tract Infections, Skin Infection
- Trial name
- NCT05880069
- Testing
- Pathogen resistant phenotype
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Universitario Virgen Macarena
Urinary Tract Infections
Efficacy and Safety of Cefditoren Pivoxil Versus Ciprofloxacin in Acute Uncomplicated Cystitis
The main objective of the study is to comparatively assess the efficacy and tolerability of the drugs under study in the treatment of acute uncomplicated cystitis.
- Trial name
- NCT00598403
- Testing
- cefditoren pivoxil, Ciprofloxacin
- Where
- 30 sites in Greece, Spain
- Volunteers
- 611 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Multiple Sclerosis, Recurrent Urinary Tract Infections
D-mannose for the Prevention of UTIs in Multiple Sclerosis
This is a study to explore the feasibility of using D-mannose, a commonly used food supplement, in persons with multiple sclerosis reporting recurrent urinary tract infections.
- Trial name
- NCT02490046
- Testing
- D Mannose
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University College, London
Helicobacter Infections, Urinary Tract Infection
First Time in Man Study of Finafloxacin Hydrochloride
The purpose of this study is to study the safety of single doses and multiple doses of Finafloxacin hydrochloride in healthy volunteers. The level of Finafloxacin hydrochloride will be measured in the subjects blood and urine.
- Trial name
- NCT00483158
- Testing
- Finafloxacin hydrochloride
- Where
- Switzerland
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- MerLion Pharmaceuticals GmbH
Uncomplicated Symptomatic Urinary Tract Infections
Assess the Effects of a Limosilactobacillus Supplement on Recurrence of UTI in Healthy Women During a 6-month Period
The goal of this clinical trial is to assess the efficacy of the probiotic Limosilactobacillus reuteri 3613 for the decrease or prevent UTI occurrence in women ages 18-65 with a confirmed medical history of recurrent…
- Trial name
- NCT05793814
- Testing
- Limosilactobacillus reuteri 3613
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Church & Dwight Company, Inc.
Urinary Tract Infections
Urinary Tract Infection Due to Beta-lactamase-producing Enterobacteriaceae in Children
Urinary tract infection due to Extended-spectrum beta-lactamase producing enterobacteriaceae (E-ESBL UTI) become a frequent problem.
- Trial name
- PYELOBLSE (NCT02832258)
- Where
- 24 sites in France
- Volunteers
- 590 people
- Sponsor
- Fouad Madhi
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Urinary Tract Infection
Cranberry for the Prevention of Urinary Tract Infections
This study aims to determine whether a cranberry concentrate reduces recurrent urinary tract infections (UTIs) in women. Approximately 150 adult women will be recruited to participate in this study.
- Trial name
- NCT02454309
- Testing
- Cranberry concentrate
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Uterine Prolapse, Urinary Incontinence
The Immune Reactivity of Biofilms in Vaginal Mesh Erosion.
Aging, birth trauma and extensive pelvic surgery are the causes known to cause advanced pelvic organ prolaspe, fecal as well as urinary incontinence.
- Conditions
- Uterine Prolapse, Urinary Incontinence, Fecal Incontinence
- Trial name
- NCT00564044
- Testing
- excision of the protruding mesh and its surrounding vaginal tissue
- Where
- Taiwan
- Volunteers
- 82 people
- Sponsor
- Chang Gung Memorial Hospital
Spinal Cord Injury, Urinary Tract Infection
Effect of Cranberry Capsules on Urinary Infection Rates in Spinal Cord Injured Patients During Post Acute Rehabilitation
The purpose of this study is to establish whether cranberry capsules reduce rates of urinary tract infections during initial rehabilitation immediately after spinal cord injury.
- Conditions
- Spinal Cord Injury, Urinary Tract Infection, Rehabilitation
- Trial name
- NCT01079169
- Testing
- Cranberry capsules
- Where
- Sweden
- Volunteers
- 3 people
- Sponsor
- Uppsala University
Recurrent Urinary Tract Infection, Postmenopause
Clinical Trial on the Preventive Effect of Intravaginal Prasterone on Recurrent Urinary Tract Infections in Postmenopausal Women
Urinary tract infections (UTIs) are bothersome and more likely to occur in postmenopausal women. Frequent UTIs, as well as other problems with the urinary and genital systems such as painful sex and urinary frequency/urgency, are…
- Conditions
- Recurrent Urinary Tract Infection, Postmenopause, Postmenopausal Syndrome, Postmenopausal Symptoms
- Trial name
- NCT03854396
- Testing
- Prasterone
- Where
- United States
- Sponsor
- Olivia Cardenas-Trowers, M.D.
Bacteriuria (Asymptomatic) in Pregnancy
Treatment of Asymptomatic Bacteriuria in Pregnancy
This is a prospective randomized controlled day comparing the efficacy of three-day antimicrobial treatment of asymptomatic bacteriuria (ASB) in pregnancy to the standard seven-day treatment.
- Trial name
- NCT02911662
- Testing
- Cephalexin, Nitrofurantoin
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Trinity Health Michigan
Recurrent Urinary Tract Infections
Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health…
- Trial name
- BIrUTI (NCT04846803)
- Testing
- ABU bladder lavage, Saline bladder lavage
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck
A Study to Evaluate the Safety and Tolerability of Immunotherapy Combinations in Participants With Advanced Malignancies
This is a Phase 1, open-label, dose-escalation and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD) and clinical activity of etrumadenant (AB928) in combination with…
- Conditions
- Non-small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Breast Cancer, Colorectal Cancer
- Trial name
- NCT03629756
- Testing
- Etrumadenant, Zimberelimab
- Where
- 15 sites in United States, Australia
- Volunteers
- 48 people
- Sponsor
- Arcus Biosciences, Inc.
Kidney Transplantation, Adult
Web-Based Multi-Resource Training on the Prevention of Urinary Tract Infections in Adult Kidney Transplant Recipients
Purpose: The study aims to examine the effect of web-based multi-source training on the prevention of urinary tract infections in adult kidney transplant recipients on clinical outcomes.
- Conditions
- Kidney Transplantation, Adult, Urinary Tract Infections, Prevention
- Trial name
- NCT05821946
- Testing
- Web-Based Multi-Source Training on the Prevention of Urinary Tract İnfections
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Enlarged Prostate
3D Rotational CT Angiogram With Embolization Guidance and CBCT in Prostatic Artery Embolization
The purpose of this research study is to learn about how cone-beam Computerized Tomography scans (X-ray images taken from different angles) work together with an embolization guidance software (helps the doctor see the arteries…
- Trial name
- NCT03164629
- Testing
- cone-beam CT 3D Emboguide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami