Clinical trials: Urinary Infection
Urolithiasis
Study of Tomography of Nephrolithiasis Evaluation
This is a multi-center, randomized controlled trial of ultrasonography (ultrasound) compared to computed tomography (CT) for the initial emergency room evaluation of patients with suspected renal colic.
- Trial name
- STONE (NCT01451931)
- Testing
- Point-of-care Ultrasound, Radiology Ultrasound, Radiology CT
- Where
- 15 sites in United States
- Volunteers
- 2,776 people
- Sponsor
- University of California, San Francisco
Urinary Tract Infections, Pyelonephritis
Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)
The purpose of this study is to evaluate the efficacy, safety and tolerability of adding 125 mg or 250 mg doses of MK-7655 (relebactam) to imipenem/cilastatin in adults 18 years or older with complicated urinary tract infection…
- Trial name
- NCT01505634
- Testing
- Relebactam 250 mg, Relebactam 125 mg, imipenem/cilastatin 500 mg
- Volunteers
- 302 people
- Sponsor
- Merck Sharp & Dohme LLC
Infections, Bacterial
Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor that is being developed for the treatment of uncomplicated urinary tract infections (UTIs; acute cystitis).
- Trial name
- NCT03568942
- Testing
- Gepotidacin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infection
Bacterial Interference for Prevention of Catheter-Associated UTI: Geriatric Pilot Study
This study is a prospective pilot clinical trial investigating the use of urinary catheters coated with benign E. coli in geriatric subjects.
- Trial name
- NCT00554996
- Testing
- E. coli 83972 coated urinary catheter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Covid19, Genito Urinary Cancer
Description of the Population With Genitourinary Tumors and COVID-19
The identification of patients with genitourinary tumors who suffer from the infection by the Serious Acute Respiratory Syndrome Corona-Virus 2 (SARS-CoV-2) virus can represent multiple benefits both for themselves and for health…
- Trial name
- SOGUGCOVID (NCT04578132)
- Where
- 32 sites in Spain
- Volunteers
- 410 people
- Sponsor
- Spanish Oncology Genito-Urinary Group
Sexually Transmitted Disease, Bacterial Vaginosis
Women's Improvement of Sexual Health (WISH) Demonstration Project
The current standard of care for urogenital infections in Rwanda is syndromic management. Many urogenital infections are asymptomatic and therefore completely missed, and the management of vaginal discharge syndrome is known to…
- Conditions
- Sexually Transmitted Disease, Bacterial Vaginosis, Vaginal Candidiasis, Urinary Tract Infections
- Trial name
- WISH (NCT03045809)
- Testing
- Urogenital infection point-of-care tests
- Where
- Rwanda
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Janneke van de Wijgert
Urinary Tract Infections, Catheter-Related Infections
Short-course Methenamine Hippurate for Prevention of Post-operative UTI
The investigators will determine the efficacy of an innovative short regimen of methenamine hippurate on prevention of post-operative UTI in patients requiring short-term catheterization after pelvic reconstructive surgery…
- Trial name
- NO-UTI (NCT02358993)
- Testing
- methenamine hippurate, Ciprofloxacin
- Where
- 4 sites in United States
- Volunteers
- 201 people
- Sponsor
- University of Pennsylvania
Urinary Tract Infections
Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection
Postoperative urinary tract infections (UTIs) affect 20-30% of patients undergoing elective gynecologic surgery and have a significant socioeconomic impact and cost.
- Trial name
- NCT03099863
- Testing
- Cystoscopic Fluid containing Neosporin G. U. Irrigant, Cystoscopy
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Complicated Urinary Tract Infections
Sulopenem Followed by Sulopenem-etzadroxil/Probenecid vs Ertapenem Followed by Cipro for Complicated UTI in Adults
This is a prospective, phase 3, randomized, multicenter, double-blind, double-dummy study to compare the efficacy and safety of sulopenem followed by sulopenem-etzadroxil/probenecid versus ertapenem followed by ciprofloxacin for…
- Trial name
- NCT03357614
- Testing
- Sulopenem, Sulopenem-Etzadroxil/Probenecid, Ertapenem
- Where
- 32 sites in United States, Estonia and 3 more
- Volunteers
- 1,395 people
- Sponsor
- Iterum Therapeutics, International Limited
Infection, Cross Infection
A Safety and Efficacy Study of Doripenem in Participants With Nosocomial Pneumonia, Complicated Intra-Abdominal Infections and Urinary Tract Infections
The purpose of this study is to assess the safety and efficacy of doripenem in participants with nosocomial pneumonia (inflammation of the lungs in which the lungs become heavy; pneumonia occurring at least 48 hours after…
- Conditions
- Infection, Cross Infection, Bacterial Infections, Pneumonia, Ventilator-Associated
- Trial name
- NCT00965848
- Testing
- Doripenem
- Where
- 8 sites in Thailand
- Volunteers
- 270 people
- Sponsor
- Janssen-Cilag Ltd.,Thailand
Cross Infection, Pneumonia, Ventilator-associated
Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit
This prospective, randomized, controlled trial will compare the incidence of nosocomial infections (composite of primary bloodstream infections, catheter-associated urinary tract infections, ventilator-associated pneumonia, and…
- Conditions
- Cross Infection, Pneumonia, Ventilator-associated, Catheter-related Infections, Infection Due to Indwelling Urinary Catheter
- Trial name
- NCT01640925
- Testing
- Chlorhexidine gluconate, Standard bathing
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- Joshua Swan
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Complicated Urinary Tract Infection, Acute Pyelonephritis
Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis
Phase 3 study to evaluate the efficacy and safety of cefepime/nacubactam or aztreonam/nacubactam compared to imipenem/cilastatin in the treatment of complicated urinary tract infections (cUTI) or acute uncomplicated…
- Conditions
- Complicated Urinary Tract Infection, Acute Pyelonephritis, cUTI, AP
- Trial name
- Integral-1 (NCT05887908)
- Testing
- co-administration of cefepime and nacubactam, co-administration of aztreonam and nacubactam, imipenem/cilastatin
- Where
- 61 sites in Bulgaria, China and 7 more
- Volunteers
- 614 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
Other Acute Illnesses Presenting to the Hospital, Heart Failure
Evaluation of Implementation of a National Point-of-Care Ultrasound Training Program
This VA QUERI Partnered Evaluation Initiative will evaluate the impact of an immersive Point-of-care Ultrasound (POCUS) Training Course on provider skill acquisition and retention; the frequency of POCUS use by trained providers…
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis
- Trial name
- NCT03296280
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Complicated Urinary Tract Infection
Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections
The purpose of this study is to evaluate the safety and efficacy of intravenous CXA 101 and comparator in complicated urinary tract infection
- Trial name
- NCT00921024
- Testing
- CXA-101, Ceftazidime
- Where
- 21 sites in United States, Germany and 1 more
- Volunteers
- 129 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Urinary Tract Infections, Asymptomatic Bacteriuria
Modified Reporting of Positive Urine Cultures Collected From Long Term Care
Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations.
- Trial name
- NCT03554603
- Testing
- Modified Report
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Memorial University of Newfoundland