Clinical trials: Urinary Infections
Urinary Tract Infections, Urosepsis
Prevalence of Antimicrobial-resistant Pathogens in Patients Admitted for UTIs
Between 2013-2014, our study network of U.S. emergency departments, EMERGEncy ID NET, found that the rate of fluoroquinolone-resistant E. coli was 11.7% among all patients, 6.3% in uncomplicated and 19.9% in complicated.
- Trial name
- NCT03346603
- Testing
- urine culture and susceptibility testing
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Interstitial Cystitis, Bladder Pain Syndrome
The Female Microbiome in Patients Undergoing Bladder Instillation Therapy
The underlying pathophysiology for BPS/IC is currently an active area of research. There is speculation that there may be alteration in the bladder and vaginal microbiome that contributes to the symptomatology of BPS/IC, however…
- Conditions
- Interstitial Cystitis, Bladder Pain Syndrome, Microbial Colonization
- Trial name
- NCT05414305
- Testing
- Heparin & Alkalinized Lidocaine Bladder Instillation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Walter Reed National Military Medical Center
Recurrent Urinary Tract Infection
Phage Therapy for the Treatment of Urinary Tract Infection
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of bacteriophage therapy to treat and prevent the recurrence of a drug-resistant urinary tract infection with serious long-term effects.
- Trial name
- NCT05537519
- Testing
- Phage Therapy
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Unity Health Toronto
Bacterial Infections
Evaluation of the Artificial Intelligence-based Prescription Support Software iAST® for the Choice of Empirical and Semi-targeted Antibiotic Treatment
Inadequate treatment of infections frequently leads to complications that cause new visits to the doctor, lengthen hospital stays and can lead to sepsis, even causing the death of affected patients.
- Trial name
- EVIAST (NCT06174519)
- Testing
- Medical device simulation
- Where
- Spain
- Volunteers
- 325 people
- Sponsor
- Pragmatech AI Solutions
Urinary Tract Infections, Diagnostic Techniques and Procedures
The Impact of De-implementing Urine Dipsticks for Diagnosis of UTIs in Hospitals
The goal of this interrupted time-series analysis is to evaluate the impact of the de-implementation of urine dipsticks as a diagnostic tool for urinary tract infections (UTIs) in hospitalized patients in the North Denmark…
- Conditions
- Urinary Tract Infections, Diagnostic Techniques and Procedures, Point-of-Care Testing, Anti-Bacterial Agents
- Trial name
- NCT06750666
- Testing
- De-implementation of Urinary Dipsticks, Usual practice with no intervention
- Where
- 2 sites in Denmark
- Volunteers
- 480,000 people
- Sponsor
- Jacob Bodilsen
Urinary Tract Infection Symptomatic, Acute Pyelonephritis
Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections
The purpose of the study is to demonstrate the safety and efficacy of ZTI-01 (IV fosfomycin) as non-inferior to piperacillin/tazobactam in overall success (clinical cure and microbiologic eradication) for the treatment of…
- Conditions
- Urinary Tract Infection Symptomatic, Acute Pyelonephritis, Urinary Tract Infection Complicated
- Trial name
- ZEUS (NCT02753946)
- Testing
- ZTI-01, Piperacillin-tazobactam
- Where
- 68 sites in United States, Belarus and 14 more
- Volunteers
- 465 people
- Sponsor
- Nabriva Therapeutics AG
Urinary Tract Infection, Pyelonephritis
Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in Children
Cranberry and cranberry-lingonberry juice prevented urinary tract infections in children and in adults in our earlier clinical trials.
- Conditions
- Urinary Tract Infection, Pyelonephritis, Cystitis
- Trial name
- NCT01861353
- Testing
- Cranberry-lingonberry juice
- Where
- Finland
- Volunteers
- 113 people
- Sponsor
- University of Oulu
Urinary Tract Infections, Urinary Tract Infection (UTI)
Alternative Prophylaxis in Female Recurrent Urinary Tract Infections
Urological pathogens are effected by rising antimicrobial resistance rates due to the frequent use of antimicrobials for treatment and prophylaxis.
- Trial name
- AlP-FrUiT (NCT04095572)
- Testing
- intravesical instillation with HA-CS, intravesical instillation of sterile purified water
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Basel, Switzerland
Urinary Tract Infections, Recurrent
Effect of Hyaluronic Acid Oral Supplementation on Sexual and Urinary Symptoms of Women With Recurrent Urinary Tract Infections
Uncomplicated urinary tract infections (UTI) are one of the most common bacterial infections globally, causing a significant proportion of medical consultations in primary and outpatient settings.
- Trial name
- JalUrol (NCT06268483)
- Testing
- HA 100 mg, CS 400 mg, N-Acetylglucosamine 200 mg and vitamin C 80 mg + cranberry, D-mannose, propolis extract, tumeric and Boswellia, cranberry, D-mannose, propolis extract, tumeric and Boswellia
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Pneumonia, Skin and Soft Tissue (SST) Infection
Trial of Reducing Inpatient Antibiotic Durations in Children
Infections like pneumonia, skin and soft tissue infection (also called SSTI or cellulitis), and urinary tract infections (UTI) are some of the most common reasons children get admitted to the hospital.
- Conditions
- Pneumonia, Skin and Soft Tissue (SST) Infection, Urinary Tract Infections (UTIs)
- Trial name
- TRIAD (NCT07322146)
- Where
- 10 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of California, San Francisco
Articular Disease
Spectrum of Bacterial Infections in Rheumatology
Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020.
- Trial name
- SIBERIE (NCT05007405)
- Testing
- Groups/Cohortes
- Where
- France
- Volunteers
- 81 people
- Sponsor
- Hôpital NOVO
Asymptomatic Bacteriuria, Bacteriuria
The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria
The purpose of this study is to compare antibiotics versus no-treatment in kidney transplant recipients with asymptomatic bacteriuria.
- Conditions
- Asymptomatic Bacteriuria, Bacteriuria, Urinary Tract Infections, Kidney Transplantation
- Trial name
- BiRT (NCT01871753)
- Testing
- Anti-Infective Agents
- Where
- 15 sites in Belgium, France
- Volunteers
- 198 people
- Sponsor
- Erasme University Hospital
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Lower Urinary Tract Symptoms, Lower Urinary Tract Infection
PEEZY Midstream Urine Device Compared to Catheterized Urine Sample
Urine culture and microscopic urinalysis will be compared between 2 collection methods: PEEZY midstream urine collection, and urethral catheter collection.
- Trial name
- PEEZY (NCT03729336)
- Testing
- Midstream urine collection device, Catheter for urine collection
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Urinary Tract Infection
A Trial for the Safety and Effectiveness of a Novel Antimicrobial-Coated Foley Catheter for Reduction of CAUTI.
The primary objective of this pilot study is to demonstrate the feasibility of recruiting eligible patients for the purposes of assessing the temporal aspects and rates of Catheter Associated Urinary Tract Infection (CAUTI)…
- Trial name
- NCT01681511
- Testing
- ICET™ TIC Foley Catheter, BARD® LUBRI-SIL® IC Foley Catheter
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Innovative Chemical and Environmental Technologies, Inc
Catheter Infection, Catheter Blockage
Evaluation of the Novel Silq ClearTract Catheter in Patients With Chronic Urinary Retention
To assess the ability of the Silq ClearTract™ 100% Silicone 2-Way Foley Catheter to reduce catheter associated complications in subjects that require a long-term indwelling Foley catheter when compared to other commercially…
- Conditions
- Catheter Infection, Catheter Blockage, Catheter Related Complication, Catheter Calcification
- Trial name
- NCT05931887
- Testing
- SILQ ClearTract 100% Silicone 2-Way Foley Catheter
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Silq Technologies Corporation
Cancer
Study of Previously Collected and Stored Tissue Samples From Patients Previously Enrolled in a Completed National Cancer Institute Clinical Trial
RATIONALE: Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00904514
- Testing
- gene expression analysis, microarray analysis, mutation analysis
- Volunteers
- 241 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Catheter-Related Infections, Urinary Catheterization
The Urinary Catheterization Training on Skills, Satisfaction and Self-Confidence in Nursing Students
In our study, it is planned to use three different simulation methods. One of these; It is a low-reality simulator, a hip model.
- Trial name
- NCT05710731
- Testing
- Use of simulation in urinary catheterization training
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Recurrent Urinary Tract Infection
Phase II Clinical Trial of Vitamin D3 for Reducing Recurrence of Recurrent Lower Urinary Tract Infections
The aim of this study was to initially evaluate the optimal dose, efficacy, and safety of vitamin D3 for reducing recurrence of recurrent urinary tract infections (rUTIs).
- Trial name
- NCT04859621
- Testing
- Vitamin D3 4000 IU, Vitamin D3 2000 IU, standard antibiotic therapy
- Where
- 6 sites in China
- Volunteers
- 150 people
- Sponsor
- Zensun Sci. & Tech. Co., Ltd.
Urinary Tract Infection
The Use of the UroShield Device in Patients With Indwelling Urinary Catheters
According to the Israeli Ministry of Health requirement, this study was designed to evaluate the efficacy of the UroShield system is patients that require urinary catheterization.
- Trial name
- CAUTI (NCT00446732)
- Testing
- UroSshield
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Nanovibronix
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