Clinical trials: Urinary Infections
Urinary Tract Infections, Pyelonephritis
Safety, Tolerability, and Efficacy of MK-7655 (Relebactam) + Imipenem/Cilastatin Versus Imipenem/Cilastatin Alone for Treating Complicated Urinary Tract Infection (cUTI) (MK-7655-003)
The purpose of this study is to evaluate the efficacy, safety and tolerability of adding 125 mg or 250 mg doses of MK-7655 (relebactam) to imipenem/cilastatin in adults 18 years or older with complicated urinary tract infection…
- Trial name
- NCT01505634
- Testing
- Relebactam 250 mg, Relebactam 125 mg, imipenem/cilastatin 500 mg
- Volunteers
- 302 people
- Sponsor
- Merck Sharp & Dohme LLC
Respiratory Tract Infections, Urinary Tract Infections
Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for Treatment of Respiratory and Urinary System Infection
In the proposed study, the investigators plan to evaluate the efficacy and safety of Piperacillin Sodium and Sulbactam Sodium for Injection(2:1) for the treatment of respiratory and urinary tract acute bacterial infection.
- Trial name
- PIP-SBT (NCT01760109)
- Testing
- Piperacillin Sodium and Sulbactam Sodium
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Urinary Tract Infections, Chronic Urinary Tract Infection
Expanded Access Program Using Uromune for Patients With Recurrent Urinary Tract Infections (rUTI)
An Expanded Access Program for UROMUNE® for patients suffering from recurrent/chronic urinary tract infections of diverse etiology.
- Conditions
- Urinary Tract Infections, Chronic Urinary Tract Infection, Recurrent Urinary Tract Infection, Urinary Tract Infection Bacterial
- Trial name
- NCT04173013
- Testing
- Uromune
- Where
- 15 sites in Belgium, Czechia and 13 more
- Sponsor
- Impatients N.V. trading as myTomorrows
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Geriatric Presentation of Urinary Tract Infection, Acute Kidney Injury
Intraoperative NGAL Level in Geriatric Patients Undergoing Laparotomy
The aim of this study is to detect early renal dysfunction that may occur during the surgical procedure in geriatric patients who will undergo laparotomy surgery.
- Trial name
- NCT05030727
- Testing
- record of pNGAL
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Urinary Tract Infections
POCARED Diagnostics, LTD, Field Study Protocol
This study is designed to compare the performance of the P-1000 System, POCARED's Rapid Diagnostic System which uses optical fluorescence analysis, to standard methods of uropathogen quantification and identification.
- Trial name
- NCT01487148
- Where
- 5 sites in United States, Israel
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Pocared Diagnostics
Urinary Tract Infections
Quick-Wee Versus Bladder Stimulation System to Collect Midstream Urine From Pre-continent Infants
Urinary tract infections are common in infants. Obtaining urine from pre-continent children can be difficult and time consuming.
- Trial name
- ES-Stimquick U (NCT04587999)
- Testing
- bladder stimulation, Quick wee
- Where
- 3 sites in Canada, France
- Volunteers
- 230 people
- Sponsor
- Fondation Lenval
Bacterial Vaginosis, Candidosis Vaginal
Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal Microbiota
The aim of the present randomized double-blind placebo-controlled trial is to evaluate the efficacy of a probiotic formulation, containing the probiotic strain Lacticaseibacillus rhamnosus CA15 (DSM 33960), in the treatment of…
- Conditions
- Bacterial Vaginosis, Candidosis Vaginal, Urinary Tract Infections
- Trial name
- NCT05796921
- Testing
- Lacticaseibacillus rhamnosus CA15 (DSM 33960) probiotic strain
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Agnese Maria Chiara Rapisarda
Urinary Tract Infections
Safety and Efficacy Study of Cefepime-AAI101 in the Treatment of Complicated Urinary Tract Infections
Multi-center, randomized, double-blind, non-inferiority study of cefepime 2 g/AAI101 500 mg combination compared to piperacillin 4 g/tazobactam 500 mg in a population of adult patients with cUTI or AP.
- Trial name
- NCT03687255
- Testing
- cefepime/AAI101 combination, Piperacillin/tazobactam
- Where
- 24 sites in United States, Argentina and 17 more
- Volunteers
- 1,043 people
- Sponsor
- Allecra
Bacteriuria, Urinary Tract Infections
Asymptomatic Bacteriuria & Risk of Urinary Tract Infection in Renal Transplants
The goal of this research program is to understand the natural history of asymptomatic bacteriuria in the renal transplant patients, to determine if screening for asymptomatic bacteriuria and identification of key host…
- Conditions
- Bacteriuria, Urinary Tract Infections, Asymptomatic Infections, Transplantation Infection
- Trial name
- ASB (NCT01349738)
- Testing
- Antibiotic
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rice, James C., M.D.
Urinary Tract Infections
Modified Reporting From Indwelling Catheters
Positive urine cultures collected from indwelling catheters from inpatients will be randomized to standard reporting or modified reporting.
- Trial name
- NCT03488355
- Testing
- Modified laboratory report
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Memorial University of Newfoundland
Urinary Tract Infections
Finafloxacin 300 mg Twice a Day (b.i.d.) Versus Ciprofloxacin 250 mg Twice a Day (b.i.d) in Patients With Lower Uncomplicated UTI (uUTI)
To compare the bacteriological eradication rates of Finafloxacin and Ciprofloxacin in female patients with uUTI.
- Trial name
- FLUT (NCT00722735)
- Testing
- Finafloxacin, Ciprofloxacin
- Where
- 2 sites in Germany, Singapore
- Volunteers
- 36 people
- Sponsor
- MerLion Pharmaceuticals GmbH
Type 2 Diabetes, Urinary Tract Infections
SGLT-2 and DPP-4 Inhibition, Subclinical Inflammation of the Genito-urinary Tract and Risk of Infections.
In this observational study, 60 subjects with type 2 diabetes (T2D) and eligible, as per good clinical practice, for therapy with SGLT-2 inhibitor, will be randomized to receive a SGLT-2 inhibitor or a fixed dose combination of…
- Trial name
- UTI-flog (NCT04735042)
- Testing
- Empagliflozin / Linagliptin or Dapagliflozin/Saxagliptin Pill, Empagliflozin or Dapagliflozin Pill
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Pisa
Pneumonia, Bacterial, Pneumonia Childhood
Discharge Stewardship in Children's Hospitals
The goal of this interventional study is to test if a discharge stewardship bundle is effective at reducing inappropriate antibiotic prescriptions at hospital discharge for children with the three common infections…
- Conditions
- Pneumonia, Bacterial, Pneumonia Childhood, Urinary Tract Infections, Soft Tissue Infections
- Trial name
- DISCO (NCT05826873)
- Testing
- Discharge antibiotic stewardship intervention
- Where
- 5 sites in United States
- Volunteers
- 1,131 people
- Sponsor
- Children's Hospital of Philadelphia
Bacteriuria
Retained Urine Volume and Bacteriuria in Traditional Versus Vented Urine Drainage Systems
The purpose of this study is to see if there are differences in urine drainage between two types of indwelling bladder catheter systems (Foley catheter) in hospitalized patients.
- Trial name
- NCT02052674
- Testing
- Vented urinary drainage system, Non-vented urinary drainage system
- Sponsor
- University of Florida
Urinary Infection
Incidence of Post Cystography Urinary Tract Infections in the Pediatric Population
Cystography is a frequent pediatric examination, although indications have been recently restricted . Current indications in our center are: The occurrence of 2 episodes of acute pyelonephritis or 1 episode of pyelonephritis if…
- Trial name
- IUCPED (NCT03399682)
- Testing
- cystography
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Caen
Urinary Infections
Study Evaluating Piperacillin/Tazobactam in Complicated Urinary Infections.
The primary objective is to study the efficacy of piperacillin/tazobactam in patients with complicated urinary tract infections
- Trial name
- NCT00195286
- Testing
- piperacillin/tazobactam
- Where
- 27 sites in Spain
- Volunteers
- 180 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Pneumonia
Urinary Antigen Test for Stretococcus Pneumoniae Serotype Prevalence in Community Acquired Pneumonia
This is an epidemiology study for the prevalence and serotypes of pneumococcus pneumoniae in hospitalized patients with community acquired pneumonia (CAP).
- Trial name
- NCT05374018
- Testing
- urinary kit for pneumococcus antigen assay
- Where
- Hong Kong
- Volunteers
- 1,800 people
- Sponsor
- Chinese University of Hong Kong
Urinary Tract Infection in Pregnancy
Lactobacillus Reuteri for Treatment of Uncomplicated UTI in Pregnant Women
Prevalence of uro-genital infections during pregnancy move between 7% to 12% in developed countries, meanwhile in developing countries this figure moved between 14% and until 55%, such is the case of Mexico.
- Trial name
- UTIPregnant (NCT03362697)
- Testing
- Probiotics, Antibiotics
- Where
- Mexico
- Volunteers
- 150 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Febrile Urinary Tract Infection
Individualized Antibiotic Therapy in Children With Acute Uncomplicated Febrile Urinary Tract Infection
An investigator-initiated, open-label, multi-center, randomized, non-inferiority trial of children aged 3 months to 13 years with acute uncomplicated febrile urinary tract infection.
- Trial name
- NCT05301023
- Testing
- Individualized antibiotic therapy, Standard antibiotic therapy
- Where
- 8 sites in Denmark
- Volunteers
- 408 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
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