Clinical trials: Urinary Infections
Urinary Tract Infection (Diagnosis), Pregnancy
Cross-sectional Study of the Prevalence and Risk Factors of Asymptomatic Bacteriuria in Pregnancy
Asymptomatic bacteriuria (ASB) is the presence of bacteria in the urine without symptoms of urinary tract infection. It is common during pregnancy and, if left untreated, may lead to complications such as pyelonephritis, preterm…
- Trial name
- NCT07001579
- Where
- Nepal
- Volunteers
- 390 people
- Sponsor
- Nepalese Army Institute of Health Sciences
Infectious Disease
Temocillin in ESBL-Enterobacteriaceae Infections
Because of the increasing incidence of infections with multi-drug resistant enterobacteriaceae, we need alternative treatments to spare carbapenems.
- Trial name
- TMO2016 (NCT05413772)
- Testing
- Temocillin
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urinary Tract Infections
The Effect of Sonographic Bladder Compressive Technique for Bag Urine Collection in Pediatrics
Aim: to shorten the time of urination by bladder pressure stimulation in children less than 36 months of age who need urinalysis to exclude or diagnose urinary tract infections and to speed up the start time of antibiotics…
- Trial name
- NCT03152851
- Testing
- Pressure stimulus group
- Where
- 2 sites in South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Transplantation Infection
Cidofovir Versus Best Supportive Care for Hemorrhagic Cystitis
The goal of this clinical research study is to learn if adding cidofovir to the standard of care can improve symptoms of hemorrhagic cystitis caused by the BK virus as compared to standard of care alone.
- Trial name
- NCT01295645
- Testing
- Cidofovir, No Cidofovir
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- M.D. Anderson Cancer Center
Asymptomatic Bacteriuria, Urinary Tract Infections
Safety and Effectiveness of a Laboratory Intervention to Effectively NOT Treat Asymptomatic Bacteriuria
This is an observational cohort study of 1000 consecutive patients on medical and surgical wards at the Mount Sinai Hospital in Toronto who have a mid-stream urine culture ordered.
- Trial name
- Salient (NCT03445312)
- Testing
- not processing urine cultures
- Where
- Canada
- Volunteers
- 1,394 people
- Sponsor
- Mount Sinai Hospital, Canada
Urinary Tract Infections
Clinical Effectiveness and Bacteriological Eradication of 4 Short-course Antibiotics for Uncomplicated UTIs in Women.
Randomized clinical trial in which women aged 18 or older and with symptoms of uncomplicated lower urinary tract infection and a positive urine dipstick analysis will be randomized to one of the following four groups: 2-day 3 g…
- Trial name
- SCOUT (NCT04959331)
- Testing
- Fosfomycin Trometamol Salt, Nitrofurantoin, Pivmecillinam
- Where
- 33 sites in Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Asymptomatic Bacteriuria, Bacteriuria
The Bacteriuria in Renal Transplantation (BiRT) Study: A Trial Comparing Antibiotics Versus no Treatment in the Prevention of Symptomatic Urinary Tract Infection in Kidney Transplant Recipients With Asymptomatic Bacteriuria
The purpose of this study is to compare antibiotics versus no-treatment in kidney transplant recipients with asymptomatic bacteriuria.
- Conditions
- Asymptomatic Bacteriuria, Bacteriuria, Urinary Tract Infections, Kidney Transplantation
- Trial name
- BiRT (NCT01871753)
- Testing
- Anti-Infective Agents
- Where
- 15 sites in Belgium, France
- Volunteers
- 198 people
- Sponsor
- Erasme University Hospital
Urinary Tract Infections, Cystitis
Study Comparing Nitrofurantoin to Fosfomycin for Acute Urinary Tract Infection in Women
Developed before the establishment of a structured process for drug assessment, nitrofurantoin is now being prescribed frequently given the rise in multi-resistant gram-negative pathogens.
- Trial name
- AIDA-WP2 (NCT01966653)
- Testing
- nitrofurantoin, fosfomycin
- Where
- 3 sites in Israel, Poland and 1 more
- Volunteers
- 600 people
- Sponsor
- University Hospital, Geneva
Urinary Tract Infection, Bacteriuria
Evaluation of Safety and Tolerability of Nitric Oxide Impregnated Urinary Catheters
According to the World Health Organization, hundreds of millions of patients are affected by health-care associated infections worldwide each year, resulting in prolonged hospital stays, long-term disabilities, deaths, and…
- Trial name
- NCT02277171
- Testing
- Nitric Oxide impregnated catheter
- Volunteers
- 15 people
- Sponsor
- Enox Israel Ltd
Recurrent Urinary Tract Infection
Phage Therapy for the Treatment of Urinary Tract Infection
This is a single-patient, phase I/II clinical trial that aims to evaluate the potential of bacteriophage therapy to treat and prevent the recurrence of a drug-resistant urinary tract infection with serious long-term effects.
- Trial name
- NCT05537519
- Testing
- Phage Therapy
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Unity Health Toronto
Complicated Urinary Tract Infections
Evaluation of Safety, Pharmacokinetics and Efficacy of Ceftazidime and Avibactam (CAZ-AVI ) Compared With Cefepime in Children From 3 Months to Less Than 18 Years of Age With Complicated Urinary Tract Infections (cUTIs)
This study will assess the safety, tolerability and efficacy of ceftazidime and avibactam (CAZ-AVI )versus cefepime in children from 3 months to less than 18 years old with complicated urinary tract infections.
- Trial name
- NCT02497781
- Testing
- Ceftazidime -avibactam, Cefepime
- Where
- 28 sites in United States, Czechia and 7 more
- Volunteers
- 97 people
- Sponsor
- Pfizer
Bacterial Urinary Tract Infection
MicroUDxTM: a Rapid Diagnostic Tool That Will Prevent Death and Disability From Common Infections
Background \& Rational: Antibiotics are a major underpinning of modern medicine. The global rise of antimicrobial resistant (AMR) organisms is a serious world health problem.
- Trial name
- MicroUDxTM (NCT04228081)
- Where
- Canada
- Volunteers
- 10,000 people
- Sponsor
- University of Calgary
Vaginal Microbiota
Collection of Vaginal Microbiota Samples (VAGINOTYPE)
The aim of this study is to collect vaginal microbiota samples from healthy women who are subject to vaginal and urinary infections.
- Trial name
- VAGINOTYPE (NCT06486519)
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions
Kidney Transplant; Complications, Kidney Transplant Infection
Early vs Late Urinary Catheter Removal After Renal Transplantation
The purpose of this study is to compare frequency of UTI, urine leak and need for reoperation in patients after renal transplant with early or delayed Foley catheter removal.
- Conditions
- Kidney Transplant; Complications, Kidney Transplant Infection, Urinary Fistula, Urinary Tract Infections
- Trial name
- ELUCATR (NCT04815954)
- Testing
- Urinary catheter removal
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Medical University of Warsaw
Urinary Tract Infections
Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.
This is a phase 1, 2-part, double-blind (sponsor-unblinded), randomized, placebo-controlled, first time in human (FTIH) study, that includes both single-ascending and multiple-ascending dose phase to assess the safety…
- Trial name
- NCT04488770
- Testing
- GSK3882347
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Urinary Tract Infections
Safety and Efficacy of MEE-HU Medicus
Primary objective: is evaluation of the investigational product's safety and evaluation of its effect, in combination with antimicrobial treatment, on urine culture (microbiological cure, no microbial growth on 24-48 hrs…
- Trial name
- (SEM) (NCT05023395)
- Testing
- MEE-HU Medicus
- Where
- 2 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Dr. Ahmed Ismail
Urinary Tract Infection
Microbiological Characterization and Antibiotic Resistance Profiling of Providencia Spp,: An Emerging Pathogen Isolated From Urinary Tract Infections
Aims of the Research: 1. Isolation and identification of Providencia spp. from UTIs. 2. Genotypic confirmation of Providencia isolates. 3. Determination of antimicrobial sensitivity patterns of isolated Providencia spp. 4.
- Trial name
- NCT07204769
- Testing
- Antibiotic sensitivity
- Where
- Egypt
- Volunteers
- 241 people
- Sponsor
- Assiut University
Kidney Calculi, Urinary Tract Infections
Do Dynamic Urinary Leukocyte and Nitrite Changes Improve Risk Prediction for Infectious Complications Following PCNL?
Background Percutaneous nephrolithotomy (PCNL) is widely recognized as the primary surgical approach for managing sizable and anatomically complex kidney stones., yet postoperative infection-related complications remain common…
- Conditions
- Kidney Calculi, Urinary Tract Infections, Sepsis
- Trial name
- NCT07238673
- Where
- China
- Volunteers
- 346 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Urinary Tract Infection, Antibiotic Use
Optimizing Antibiotic Use in Long Term Care
The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic…
- Trial name
- NCT00243360
- Testing
- diagnostic and treatment clinical algorithms
- Where
- Canada
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Recurrent Urinary Tract Infection
GAG Replacement vs URethral DIlAtatioN
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women.
- Trial name
- GUARDIAN (NCT03861260)
- Testing
- Rigid cystoscopy with urethral dilatation, Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
- Where
- United Kingdom
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
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