Clinical trials: Urinary Infections
Urinary Tract Infections
Urinary Tract Infections Caused by ESBL-producing Enterobacteria
The aim of this study was to compare the etiologic agents, the antimicrobial resistance rates, and the risk factors associated with a HA-UTI and CA-UTI among complicated and uncomplicated UTI patients in a tertiary-care hospital…
- Trial name
- NCT03501901
- Testing
- Antibiotic susceptibility test
- Volunteers
- 353 people
- Sponsor
- Universidad Autonoma de Nuevo Leon
Urinary Incontinence, Urinary Tract Infections
Can the Use of Uricap Female Device Lead to Better Care for Women > 75+Years?
The purpose of the study is to evaluate if Uricap Female, an uridome for women, can be used instead of traditional incontinence aids to treat urinary incontinence (UI) among women 75 years and older.
- Conditions
- Urinary Incontinence, Urinary Tract Infections, Incontinence-associated Dermatitis, Cognition Disorders in Old Age
- Trial name
- U-PROTECT (NCT05275257)
- Testing
- Use of Uricap Female, a New Urine Collecting Device
- Where
- Sweden
- Sponsor
- Region Örebro County
Urinary Tract Infections
Antimicrobial Stewardship in UTIs in Nursing Homes
Background: The widespread inappropriate use of antimicrobial substances drives resistance development at the individual and population level all over the world.
- Trial name
- NCT04798365
- Testing
- Intervention group
- Where
- 4 sites in Austria
- Volunteers
- 326 people
- Sponsor
- Medical University of Graz
Health Care Associated Infection, Catheter-associated Urinary Tract Infection
Clinical Decision Support to Reduce Catheter Associated Urinary Tract Infections
The goal of this randomized controlled trial is to compare the effects of a clinical decision support tool consisting of a 48-hour stop order for indwelling urinary catheters versus no clinical decision support in hospitalized…
- Trial name
- NCT06454500
- Testing
- Clinical decision support
- Where
- 8 sites in United States
- Volunteers
- 79,369 people, healthy volunteers welcome
- Sponsor
- Columbia University
Bladder Cancer, Brain and Central Nervous System Tumors
High-dose ICE With Amifostine
The purpose of the study is to evaluate the combination of amifostine and high dose chemotherapy with blood stem cell support. Amifostine is a druf developed to protect normal tissues against the toxicities of chemotherapy and…
- Conditions
- Bladder Cancer, Brain and Central Nervous System Tumors, Carcinoma of Unknown Primary, Extragonadal Germ Cell Tumor
- Trial name
- NCT00003657
- Testing
- filgrastim, Amifostine, Carboplatin
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Dana-Farber Cancer Institute
Urinary Tract Infections
Ertapenem Administered Subcutaneously Versus Intravenously
Infections requiring intravenous antimicrobial therapy are very common events in patients with advanced cancer. Nevertheless, these patients frequently present vascular damages becoming extremely difficult to access and maintain…
- Trial name
- NCT03218800
- Testing
- Ertapenem
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Respiratory Tract Infections, Urinary Tract Infections
Study on Ceftazidime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection
In the proposed study, the investigators plan to evaluate the efficacy and safety of Ceftazidime Sodium and Sulbactam Sodium for Injection(2:1) for the treatment of respiratory and urinary tract acute bacterial infection.
- Trial name
- CAZ-SBT (NCT01601093)
- Testing
- High dose, Low dose, Cefoperazone and Sulbactam Sodium (CFP/SUB)
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Urinary Tract Infections
Identification of Predictive Blood Biomarkers of Recurrent Urinary Tract Infections
Urinary tract infections affect more than 130 million people worldwide each year. Almost 50% of women will have at least one urinary tract infection during their lifetime, usually cystitis.
- Trial name
- Predict-UTI (NCT03819712)
- Testing
- Collection of blood samples, Collection of fecal samples, Collection of urine samples
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Urinary Tract Infections
A Study to Investigate the Pharmacokinetics of RO7079901 and Meropenem in Participants With a Complicated Urinary Tract Infection
This is a non-randomized, open-label, one-treatment, one group study in participants with complicated urinary tract infection (cUTI) including pyelonephritis to characterize the pharmacokinetics of RO7079901 co-administered with…
- Trial name
- NCT03174795
- Testing
- RO7079901, Meropenem
- Where
- 14 sites in United States, Hungary and 3 more
- Volunteers
- 20 people
- Sponsor
- Hoffmann-La Roche
Urinary Tract Infections, Recurrent
Bovine Colostrum for Prophylaxis Against Recurrent Urinary Tract Infection in Children
Prebiotics as bovine colostrum are considered as a valuable supplement in the prevention of upper respiratory tract infections, gastrointestinal tract infections and neonatal sepsis.
- Conditions
- Urinary Tract Infections, Recurrent, Child, Prevention & Control
- Trial name
- NCT06164600
- Testing
- Bovine colostrum
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax
Special Drug Use Investigation of Ciproxan Injection in Pediatrics
The objective in this study is collecting post-marketing information on the safety and efficacy of Ciproxan injection under the routine clinical practice.
- Trial name
- NCT02555059
- Testing
- Cipro (Ciprofloxacin, BAYQ3939)
- Where
- Japan
- Volunteers
- 48 people
- Sponsor
- Bayer
Pyuria, Urinary Tract Infections
Effect of Adjuvant Treatment With Compound Cranberry Extract Tablets in Acute Bacterial Cystitis.
In conventional treatment for non-complicated bacterial cystitis, 3-day oral antibiotics could achieve good cure rate. However, severe lower urinary tract symptoms were most bothersome and only could be partially relieved by…
- Trial name
- NCT00305071
- Testing
- compound cranberry extract tablet
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Min-Sheng General Hospital
Infection Control
Preventability of Infections in Residents of French Nursing Homes
STUDY HYPOTHESIS : An infection prevention program adapted for the nursing home context can reduce by 5% the number of infections (urinary, upper and lower respiratory and gastrointestinal) in elderly residents in nursing homes.
- Trial name
- ENLIL (NCT01069497)
- Testing
- Prevention of infections program
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Observatoire du Risque Infectieux en Gériatrie
Acute Kidney Injury, Septic Shock
Does Urinary TIMP2 and IGFBP7 Can Identify High Risk Patients of Progression From Mild and Moderate to Severe Acute Kidney Injury During Septic Shock?
Septic shock is one of the leading causes of death in patients admitted to the intensive care unit (ICU). Acute kidney injury (AKI) occurs in almost 50% of septic patients and is associated with significant mortality.
- Trial name
- HEMOCHECK (NCT03547414)
- Testing
- Nephrocheck test
- Where
- France
- Volunteers
- 110 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hemorrhagic Cystitis
Evaluation of the Safety and Efficacy of LB-DTK-BKV in Patients With BK Virus-Associated Hemorrhagic Cystitis Following Allogeneic Hematopoietic Stem Cell Transplantation
The goal of this clinical trial is to assess efficacy of BK virus specific T cells (LB-DTK-BKV) to treat pediatric, adolescent, and adult patients with BK virus-associated hemorrhagic cystitis after allogenic hematopoietic stem…
- Trial name
- NCT07638332
- Testing
- LB-DTK-BKV, Standard-of-care
- Where
- 9 sites in South Korea
- Volunteers
- 42 people
- Sponsor
- LucasBio
Bronchitis, Sinusitis
Fluoroquinolone Associated Disability
The purpose of this study is to: 1) describe drug utilization for Fluoroquinolone(FQ), Azithromycin (AZ) and Sulfamethoxazole/Trimethoprim(ST) in the entire Truven MarketScan Commercial Claims and Encounters database (CCAE)…
- Conditions
- Bronchitis, Sinusitis, Urinary Tract Infections
- Trial name
- NCT03535558
- Testing
- Fluoroquinolone (FQ), Azithromycin (AZ), Sulfamethoxazole/Trimethoprim (ST) Fixed Dose Combination
- Where
- United States
- Volunteers
- 239,306 people
- Sponsor
- Janssen Research & Development, LLC
Catheter-Associated Urinary Tract Infections (CAUTIs), Kidney Transplantation
Early (Postoperative Day 3) Versus Standard (Postoperative Day 6) Urethral Catheter Removal After Living Donor Kidney Transplantation
Urinary tract infection is one of the most common complications after kidney transplantation and is associated with increased morbidity, prolonged hospitalization, and impaired graft outcomes.
- Trial name
- (EARLY-KTx) (NCT07681843)
- Testing
- Early urethral catheter removal, Standard urethral catheter removal
- Where
- Israel
- Volunteers
- 172 people
- Sponsor
- Fahim Kanani
Urinary Tract Infections
Diagnostic Accuracy of Point of Care Test of First Voided Urine Compared to Midstream Voided Urine in Primary Care
The aim of this study is to determine if sampling technique of urine affects diagnostic modalities in primary care. Furthermore it aims to determine if there is difference in the accuracy of the point-of-care test, when the urine…
- Trial name
- NCT02585115
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Copenhagen
Cancer
Intravenous VEGF Trap in Treating Patients With Relapsed or Refractory Advanced Solid Tumors or Non-Hodgkin's Lymphoma
RATIONALE: Intravenous VEGF Trap may stop the growth of solid tumors or non-Hodgkin's lymphoma by stopping blood flow to the cancer.
- Trial name
- NCT00082823
- Testing
- ziv-aflibercept
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Regeneron Pharmaceuticals
Nephrolithiasis, Urinary Tract Infection (UTI)
Endourology Disease Group Excellence (EDGE) Consortium: Antibiotics (Abx) for Percutaneous Nephrolithotomy (PCNL) Part 2
This study will be a multi-institutional randomized clinical trial of a short course of pre-operative antibiotic prophylaxis in addition to perioperative antibiotics prior to undergoing percutaneous nephrolithotomy.
- Conditions
- Nephrolithiasis, Urinary Tract Infection (UTI), Sepsis
- Trial name
- PNLABXPART2 (NCT02829060)
- Testing
- Nitrofurantoin 100 MG, 7d, Gentamicin, 5mg/kg, Ampicillin 2g
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- University of California, San Diego
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