Clinical trials: Urinary Infections
Bacterial Vaginosis, Candidiasis
Vaginal Ecosystem and Network in the United States Study
The central premise of this study is that the intricate balance and diversity of the vaginal microbiome plays a pivotal role in the onset, progression, and severity of various gynecological conditions.
- Conditions
- Bacterial Vaginosis, Candidiasis, Urinary Tract Infections, Genitourinary Syndrome of Menopause
- Trial name
- VENUS (NCT06472765)
- Testing
- Vaginal Swab Collection
- Where
- 21 sites in United States, Canada
- Volunteers
- 3,250 people, healthy volunteers welcome
- Sponsor
- Vaginal Biome Science
Urinary Tract Infections
Early or Late Foley Removal After Thoracotomy
Is the early removal of Foley catheter safe in patients undergoing general thoracic surgery with an epidural catheter in place?
- Trial name
- NCT01611519
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Interstitial Cystitis, Recurrent Cystitis
Evaluating the Efficacy and Patient Experience of Catheter-Free Intravesical Instillation
This study aims to evaluate a catheter-free method for delivering medications directly into the bladder, known as intravesical instillation, which is commonly used to treat conditions such as interstitial cystitis/bladder pain…
- Conditions
- Interstitial Cystitis, Recurrent Cystitis, Haemorrhagic Cystitis, Bladder Cancer
- Trial name
- NOCATIN (NCT06719232)
- Testing
- Catheter-Free Intravesical Instillation with a special syringe adapter
- Where
- 2 sites in Hungary
- Volunteers
- 300 people
- Sponsor
- Jahn Ferenc South Pest Teaching Hospital
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Complications; Catheter, Urinary Infection or Inflammation
BIP Foley in Prevention of CAUTI at Rehab Station
This is a prospective, cross-over, randomized, controlled, partly blinded study evaluating safety and performance of noble metal alloy urinary Catheters (BIP Foley, Bactiguard AB) of both latex and silicone.
- Trial name
- CDOC (NCT02808000)
- Testing
- BIP Foley (latex) or BIP Foley -silicone, Standard catheter
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- Bactiguard AB
Uncomplicated Urinary Tract Infection
Clinical Trial of Pivmecillinam Hydrochloride Tablets in the Treatment of Uncomplicated Urinary Tract Infection
the purpose of this study is to evaluate the efficacy and safety of pivmecillinam hydrochloride tablets in the treatment of uncomplicated urinary tract infection in China
- Trial name
- NCT05545137
- Testing
- Pivmecillinam hydrochloride tablets, Fosfomycin Tromethamine Granules
- Where
- 10 sites in China
- Volunteers
- 299 people
- Sponsor
- Benova (Tianjin) Innovative medicine Research Co., Ltd.
Urinary Tract Infections
The Effectiveness of a Bacteriophobic Coating on Urinary Catheters
To assess if a bacteriophobic coating prevents biofilm and host protein accumulation on urinary catheters and inflammatory protein release in urine following catheterization
- Trial name
- PRO033CSP (NCT05719753)
- Testing
- Camstent Coated Catheter, Standard Care
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Camstent Ltd.
Urinary Tract Infection, Respiratory Tract Infection
Prolonged Infusion Cefepime and Nosocomial Infections
It is advocated that prolonged infusion of beta-lactamic antibiotics provides better bactericidal effect. The aim of the present study is to randomize patients a to extended cefepime infusion regimen (lasting four hours) or to a…
- Trial name
- PICNIC (NCT02568800)
- Testing
- Prolonged Cefepime Infusion, Usual Cefepime Infusion
- Where
- Brazil
- Volunteers
- 134 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Pyelonephritis, Complicated Urinary Tract Infection
Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis
The project aims to investigate bacterial metallophores as potential diagnostic markers of acute pyelonephritis and complicated urinary tract infections.
- Trial name
- NCT05674032
- Where
- Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Thomayer University Hospital
Urinary Tract Infections (UTIs)
Community Antibiotic Use, Susceptibility and ResisTance Among Patients With Urinary Tract Infections (CAST-UTI)
1. General objective This pilot study aims to compare the prevalence of resistance in bacteria causing UTIs among patients seeking care outside the hospital settings (CDROs) to the WHO-GLASS data. 2.
- Trial name
- CAST-UTI (NCT07012421)
- Where
- Uganda
- Volunteers
- 890 people
- Sponsor
- St George's, University of London
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Urinary Tract Infection Complicated, Kidney Stones
Resistance Characteristics and Development of Diagnostic Model for Postoperative UTI in Patients With Kidney Stones
The combined detection of HBP, ADPN, NGAL, and hs-CRP enables the construction of a highly efficient diagnostic model, offering a novel strategy for early infection identification and risk stratification after surgery.
- Conditions
- Urinary Tract Infection Complicated, Kidney Stones, Antimicrobial Resistance
- Trial name
- NCT06946667
- Testing
- the UTI group, the Non-UTI group
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Xingxin Jiang
Acute Pyelonephritis
Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection
Hypothesis: Administration of corticoids (dexamethasone) together with the conventional antibiotherapy in the acute phase of a febrile urinary tract infection could reduce the risk of renal scarring after 6 months of the…
- Trial name
- DEXCAR-0212 (NCT02034851)
- Where
- 7 sites in Spain
- Volunteers
- 183 people
- Sponsor
- Institut Investigacio Sanitaria Pere Virgili
Urinary Tract Infections
Morbidity Rate for UTI Through Use of PCR-Based Diagnosis and Management
This retrospective study is to determine if the use of PCR for detection and identification of pathogens in UTI along with antimicrobial susceptibility information, affords more efficacious treatment of UTI, as compared to…
- Trial name
- NCT04108910
- Testing
- Guidance UTI
- Volunteers
- 66,381 people
- Sponsor
- Pathnostics
Urinary Tract Infections, Pyelonephritis
NRX-101 for Complicated Urinary Tract Infection (UTI) Including Pyelonephritis
The goal of this clinical study is to test NRX101 in participants with complicated urinary tract infections including pyelonephritis.
- Trial name
- NCT06128213
- Testing
- NRX101 (a fixed dose combination of D-cycloserine (DCS) and lurasidone HCl (lurasidone))
- Volunteers
- 13 people
- Sponsor
- NeuroRx, Inc.
Urinary Tract Infections
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
The purpose of this research study is to determine if gentamicin is as effective treatment of acute uncomplicated cystitis (urinary tract infection) using aminoglycosides versus the current standards of care.
- Trial name
- NCT05702762
- Testing
- Gentamicin, Standard of Care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Urinary Tract Infections, Urosepsis
Prevalence of Antimicrobial-resistant Pathogens in Patients Admitted for UTIs
Between 2013-2014, our study network of U.S. emergency departments, EMERGEncy ID NET, found that the rate of fluoroquinolone-resistant E. coli was 11.7% among all patients, 6.3% in uncomplicated and 19.9% in complicated.
- Trial name
- NCT03346603
- Testing
- urine culture and susceptibility testing
- Where
- United States
- Volunteers
- 801 people
- Sponsor
- Olive View-UCLA Education & Research Institute
Urinary Tract Infections
Diagnosis and Treatment of Urinary Tract Infection Using DNA Polymerase Chain Reaction Versus Urine Culture
Adults 18 years or older with urinary tract infection (UTI) symptoms. Participants will be assigned to either the urine culture group or the DNA PCR study group by randomization.
- Trial name
- NCT06808451
- Testing
- DNA PCR, Urine Culture
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University Hospitals Cleveland Medical Center
Urinary Tract Infections, Urinary Catheterization
Ureteral Stent Exchange Abstention in Urinary Tract Infections
The Committee of Infectiology of the French Association of Urology (CIAFU) provided, for the first time in 2020, comprehensive guidelines for ureteral stent-associated urinary tract infections (USAUTI) prevention, diagnosis and…
- Trial name
- JJ-change-UTI (NCT06503588)
- Testing
- Guidelines promoting surgical abstention
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Central Hospital, Nancy, France
Spinal Cord Injuries, Urinary Tract Infections
Immunomodulation Therapy for Urinary Tract Infections
Urinary tract infections (UTI) represent one of the most common morbidities in individuals with spinal cord injury (SCI) and reason for re-hospitalization.
- Trial name
- UROVAXOM-P (NCT04049994)
- Testing
- Uro-Vaxom
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
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