Clinical trials: Urinary Infections
Urinary Tract Infection (Diagnosis)
'Improving Urinary Tract Infection Diagnosis in Older Patients: Validation of a Biomarker Panel (UTI-GOLD)'
The goal of this study is to improve the diagnosis of urinary tract infections (UTI) in older people (≥65 years). The main research questions are: Research questions What is the optimal cut-off for each individual biomarker…
- Trial name
- UTI-GOLD (NCT06610721)
- Testing
- Urine Biomarkers
- Where
- Netherlands
- Volunteers
- 264 people
- Sponsor
- Leiden University Medical Center
Complicated Urinary Tract Infection, Acute Pyelonephritis
P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales
This study is a multi-center, randomized, single-blind, parallel-group study to assess the efficacy and safety, when nacubactam is coadministered with cefepime or aztreonam, compared with best available therapy (BAT), in the…
- Conditions
- Complicated Urinary Tract Infection, Acute Pyelonephritis, Hospital-acquired Bacterial Pneumonia, Ventilator-associated Bacterial Pneumonia
- Trial name
- Integral-2 (NCT05905055)
- Testing
- co-administration of cefepime and nacubactam, co-administration of aztreonam and nacubactam, BAT
- Where
- 54 sites in China, Croatia and 12 more
- Volunteers
- 126 people
- Sponsor
- Meiji Seika Pharma Co., Ltd.
SIRS, Sepsis
Urinary Proteomics Analysis for Sepsis and Prognosis
As a noninvasive examination, urinary proteomics is a very useful tool to identify renal disease. The purpose of the present study was to find differential proteins among patient with SIRS and sepsis(included survivors and…
- Trial name
- NCT01493492
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Chinese PLA General Hospital
Urinary Tract Infection, Cellulitis
Perspectives on Antibiotics and Tracking Symptoms in Children
The study will assess families' perspectives and decision-making regarding the duration of oral antibiotic courses prescribed to children (4-17 years) who present with uncomplicated bacterial infections at the Royal Children's…
- Conditions
- Urinary Tract Infection, Cellulitis, Impetigo, Pharyngitis
- Trial name
- PATSy (NCT07093749)
- Testing
- Garmin Smartwatch
- Where
- Australia
- Volunteers
- 300 people
- Sponsor
- Murdoch Childrens Research Institute
COVID-19 Infection, Genitourinary Cancer
Impact of COVID-19 on GU Disease
The purpose of this research study is to identify patients with GU disease with active or past COVID-19 infection. Participants will be asked to: Complete an Online COVID-19 Questionnaire.
- Conditions
- COVID-19 Infection, Genitourinary Cancer, Benign Urologic Conditions
- Trial name
- NCT04761107
- Where
- United States
- Volunteers
- 15,240 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Stone, Ureter Obstruction
Is it Safe to Advance a Guidewire Through a Previously Placed Double j Stent?
In this prospective randomized controlled study, it is aimed to investigate the effects of guidewire advanced through a previously placed double j stent on postoperative complications, operation time and efficacy.
- Conditions
- Kidney Stone, Ureter Obstruction, Stent Complication
- Trial name
- NCT05265936
- Testing
- Passing a guidewire through a double j stent, Double J stent removal and guidewire insertion
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Ankara Training and Research Hospital
Sexually Transmitted Infections, Schistosoma Haematobium
Urogenital Schistosomiasis and Sexually Transmitted Infections in Madagascar
A cross-sectional study of urogenital schistosomiasis and sexually transmitted infections (STI) prevalence and associated morbidity in a rural community in Madagascar.
- Trial name
- FGS/MGS/STI (NCT00713999)
- Testing
- Treatment with anti-STI and anti-schistosoma regimens
- Where
- Madagascar
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Bloodstream Infections (BSI) Due to CRE, Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE
A Study of Plazomicin Compared With Colistin in Patients With Infection Due to Carbapenem-Resistant Enterobacteriaceae (CRE)
This was a Phase 3 study containing a randomized open-label superiority cohort (Cohort 1) comparing the efficacy and safety of plazomicin with colistin when combined with a second antibiotic (either meropenem or tigecycline) in…
- Conditions
- Bloodstream Infections (BSI) Due to CRE, Hospital-Acquired Bacterial Pneumonia (HABP) Due to CRE, Ventilator-Associated Bacterial Pneumonia (VABP) Due to CRE, Complicated Urinary Tract Infection (cUTI) Due to CRE
- Trial name
- CARE (NCT01970371)
- Testing
- plazomicin, colistin, meropenem
- Volunteers
- 69 people
- Sponsor
- Achaogen, Inc.
Urinary Infection
Position of Children During Urine Collection: Evaluation Study
Urinary tract infection (UTI) is a frequently suspected cause of fever in young children, justifying urine cultures. Sampling procedures are decisive for the reliability of UTI diagnosis.
- Trial name
- PUCES (NCT01862822)
- Testing
- upright position
- Where
- France
- Volunteers
- 803 people
- Sponsor
- University Hospital, Limoges
Recurrent Urinary Tract Infections
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement containing Lactiplantibacillus plantarum PBS067, Lacticaseibacillus rhamnosus LRH020, and Bifidobacterium animalis…
- Trial name
- BIO-RUTI-26 (NCT07884929)
- Testing
- Dietary Supplement containing probiotics
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Synbalance S.r.l.
Urinary Tract Infection(UTI), Recurrent Urinary Tract Infections
Emotional Urinary Tract Infection
This project proposes a rigorous investigation into the psychological impact of positive urine culture results and recurrent urinary tract infections (UTIs) in women, with a particular focus on Interstitial Cystitis and Bladder…
- Trial name
- UTI (NCT07191041)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Northwell Health
Urinary Tract Infections
Fosfomycin Versus Standard of Care in Children With Antibiotic-resistant Urinary Tract Infections
Urinary tract infections (UTIs) are among the most common bacterial infections in children. Up to 50% of UTI's are caused by multi-drug resistant ESBL-producing gram negative bacteria that do not respond to treatment with oral…
- Trial name
- FosUTI (NCT05709028)
- Testing
- Fosfomycin, Standard of care antibiotics
- Where
- 5 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Sydney
Recurrent Urinary Tract Infections in Women
Prophylactic Use of Cranberries in Recurrent Bacterial Cystitis in Women
To investigate if oral administration of 240mg PAC of cranberries can reduce the number of episodes of acute bacterial cystitis and improve general QoL in women with recurrent bacterial cystitis.
- Trial name
- NCT03032003
- Testing
- Cysticlean
- Volunteers
- 160 people
- Sponsor
- University of Thessaly
Vesicoureteral Reflux
Bacterial and Host Genetic Risk Factors in Acute Pyelonephritis
No single host or pathogen trait identified by previous research can be correlated with all cases of childhood acute pyelonephritis or APN (i.e., kidney/upper urinary tract infections) and APN-associated renal scarring (the…
- Trial name
- NCT01137929
- Sponsor
- Hans Pohl
Urinary Tract Infections
TRA for Preventing Symptomatic Urinary Tract Infection Among High-risk Elderly Residing in Nursing Homes
Urinary tract infection (UTI) is one of the most common infection in nursing home residents, and symptomatic UTI in the nursing home setting is the most frequent reason for hospitalization and antimicrobial therapy in Taiwan.
- Trial name
- NCT04272437
- Testing
- Concentrated herbal extract granules TRA
- Where
- Taiwan
- Volunteers
- 162 people
- Sponsor
- Changhua Christian Hospital
Urinary Tract Infections, Transplant-Related Disorder
Treatment Chronic UTI Post Kidney Transplant
Urinary tract infections (UTIs) with extended-spectrum -lactamase (ESBL)-positive Enterobacteriums (ESBL-E) are a common infectious complication of renal transplant recipients, with 10% of patients suffering from UTIs with ESBL-E…
- Trial name
- NCT05967130
- Testing
- Phage
- Where
- Iran
- Volunteers
- 5 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Recurrent Urinary Tract Infection
Effect of Nanotechnology Structured Water Magnalife for the Prevention of Recurrent Urinary Tract Infections.
This study investigates nanotechnology structured water magnalife in urology and to test its effects against lower urinary tract infections (UTI) in females.
- Trial name
- NCT04306731
- Testing
- Nanotechnology Structured water Magnalife, Trimethoprim, Ordinary bottled drinking water
- Where
- Iraq
- Volunteers
- 437 people
- Sponsor
- University of Sulaimani
Urinary Tract Infection
Management of Urinary Tract Infections in Primary Care Facilities.
The Emergency Ward Center in Oslo has the last two years used a questionnaire to identify patients who qualify for treatment of acute cystitis by the use of a delegation form.
- Trial name
- NCT01132131
- Testing
- Delegation form
- Where
- Norway
- Volunteers
- 443 people
- Sponsor
- University of Oslo
Kidney Stones
Durability of Flexible Ureteroscopes and Causes of Infection During Flexible Ureterorenoscopy
This is an observational study in which data on consecutive patients who undergo ureterorenoscopy with the use of a flexible ureterorenoscope are collected.
- Trial name
- NCT03087812
- Where
- Netherlands
- Volunteers
- 400 people
- Sponsor
- Clinical Research Office of the Endourological Society
Urinary Tract Infections
EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care
Cystitis is the most frequent reason for women to visit their general practitioner. More than 600.000 women suffer from urinary tract infections in The Netherlands each year.
- Trial name
- EXFOCY (NCT05254808)
- Testing
- Fosfomycin, Nitrofurantoin
- Where
- 4 sites in Netherlands
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- MJM Bonten
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