Clinical trials: Urinary Infections
Tumors, Cardiovascular Diseases
Research on the Application and Mechanism of New Biological Probes in Biomedicine
Fluorescence is one of the most commonly used research and detection techniques in the field of biomedical science. The characteristics of fluorescent probe directly affect the performance and application of fluorescence analysis…
- Conditions
- Tumors, Cardiovascular Diseases, Respiratory System Diseases, Digestive System Diseases
- Trial name
- NCT04977739
- Testing
- No intervention
- Where
- China
- Volunteers
- 737 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Complicated Urinary Tract Infection, Acute Pyelonephritis
Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract Infection
Sulopenem etzadroxil/probenecid is available to clinicians through an Expanded Access Program for the treatment of complicated urinary tract infections due to quinolone nonsusceptible uropathogens after an initial course of…
- Trial name
- NCT04682834
- Testing
- Sulopenem Etzadroxil/Probenecid
- Sponsor
- Iterum Therapeutics, International Limited
Recurrent UTIs, Catheter-Related Infections
Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children
Background: Urinary tract infections (UTIs) are a common and costly cause of doctor visits for children. Frequent UTIs trigger kidney damage that leads to serious diseases like high blood pressure, pregnancy complications, and…
- Trial name
- Nissle 1917 (NCT01696227)
- Testing
- Nissle 1917
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Female Urogenital Diseases, Vaginal Atrophy
Investigation of Microbiomes of Postmenopausal Women Looking for Outcomes and Response to Estrogen Therapy
In this proposed pilot study, 16S ribosomal RNA (rRNA) gene sequencing will be used in the analysis of bacterial communities (microbiomes) in postmenopausal women with vulvovaginal atrophy (VVA) before and after eight weeks of…
- Conditions
- Female Urogenital Diseases, Vaginal Atrophy, Postmenopausal Atrophic Vaginitis, Genitourinary Disease
- Trial name
- IMPLORE (NCT03996603)
- Testing
- Conjugated Estrogens Cream
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Alabama at Birmingham
Catheter-Associated Urinary Tract Infection
Vitamin C Effectiveness in Preventing Urinary Tract Infections After Gynecological Surgeries
Double-blind placebo-controlled randomized trial aiming to assess the role of Vitamin C supplementation in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT05913180
- Testing
- Ascorbic Acid 1000 MG
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- American University of Beirut Medical Center
Critically Ill
Coated Devices to Decrease Infection in the Intensive Care Unit
Pilot explanatory, randomized, open label, controlled trial. Critically ill patients which will demand placement of invasive devices for organ support (endotracheal tube, central venous catheter and urinary Foley catheter) will…
- Trial name
- CRITIC (NCT03868241)
- Testing
- Coated devices, Control
- Where
- 6 sites in Brazil
- Volunteers
- 103 people
- Sponsor
- Hospital do Coracao
Radiation Cystitis, Urinary Tract Infection (Diagnosis)
Chronic Radiation Cystitis and Effect of Hyperbaric Oxygen Therapy on Patient Reported Outcomes and Urine Inflammatory Biomarkers
Collection of urine, blood, and tissue samples from patients undergoing hyperbaric oxygen therapy
- Trial name
- NCT07368647
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rachel A. Moses
Urinary Tract Infections
Observational Follow-up Study of REGATTA
Observational follow-up study of patients included in the clinical trial REGATTA.
- Trial name
- REGATTA II (NCT03176563)
- Testing
- Arctuvan, Fosfomycin
- Where
- 47 sites in Germany
- Volunteers
- 398 people
- Sponsor
- University Medical Center Goettingen
Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection
A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea
The purpose of this study is to learn about the safety and effectiveness of Zavicefta once released into the markets in Korea. This study is to learn about Zavicefta in patients with difficult types of infections in the abdomen…
- Conditions
- Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection, Hospital-acquired Pneumonia
- Trial name
- NCT05733104
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Pfizer
Uterine Prolapse, Cystocele
Prophylactic Antibiotic Treatment During Vaginal Repair
Prolapse of the uterus, bladder and rectum is a common condition in multiparous and/or elderly women. The number of operations for vaginal repair is increasing in Denmark, but there is no consensus or evidence found about the…
- Conditions
- Uterine Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT00162604
- Testing
- Cefuroxime
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Hvidovre University Hospital
Urinary Retention, Chronic Kidney Infection
Comparison of Two Bladder Catheterization Strategies in Thoracic Surgery Patients With an Enhanced Recovery After Surgery (ERAS)
General anesthesia, thoracic epidural, and morphine inhibit the urination process and promote postoperative Acute Urinary Retention (AUR) after thoracic surgery.
- Conditions
- Urinary Retention, Chronic Kidney Infection, Urinary Infection
- Trial name
- URICATHOR (NCT05611255)
- Testing
- Systematic Intermittent Catheterization, Bladder Scan Guided Catheterization
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Montpellier
Spinal Cord Injuries
Intravesical Glycosaminoglycan Instillation and Urinary Tract Infection in Acute Spinal Cord Injury
The purpose of this study is to assess the safety and feasibility of administering glycosaminoglycan (GAG) therapy, iAluRil®, intravesically in individuals with acute spinal cord injury (SCI), commencing within the first ten days…
- Trial name
- NCT03945110
- Testing
- iAluRil® intravesical instillations
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- The University of Western Australia
Urinary Tract Infections
A Study to Evaluate Gepotidacin Exposure in Breast Milk of Healthy Lactating Women
This study aims to evaluate the pharmacokinetic of gepotidacin in fed healthy lactating women.
- Trial name
- NCT07645235
- Testing
- Gepotidacin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Infection Control
Preventability of Infections in Residents of French Nursing Homes
STUDY HYPOTHESIS : An infection prevention program adapted for the nursing home context can reduce by 5% the number of infections (urinary, upper and lower respiratory and gastrointestinal) in elderly residents in nursing homes.
- Trial name
- ENLIL (NCT01069497)
- Testing
- Prevention of infections program
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Observatoire du Risque Infectieux en Gériatrie
Urinary Tract Infections, Communication
Communication and Compliance for Antibiotic Prescribing by General Practice to Nursing Home Residents With Suspected UTI
Antibiotic resistance is becoming a bigger problem. If the problem remains unsolved, the WHO predicts a return to the pre-antibiotic era.
- Conditions
- Urinary Tract Infections, Communication, Compliance, Medication
- Trial name
- NCT03700060
- Where
- Denmark
- Volunteers
- 459 people
- Sponsor
- Research Unit Of General Practice, Copenhagen
Uncomplicated Urinary Tract Infections, Urinary Tract Infections
Safety, Tolerability, Pharmacokinetic and Microbiological Investigation of GSK3882347 in Female Participants With Urinary Tract Infections
This phase 1b study is a double-blind, double-dummy, nitrofurantoin-controlled study designed to evaluate microbiological response at the test of cure (ToC) visit along with safety, tolerability and pharmacokinetic (PK) response…
- Trial name
- NCT05138822
- Testing
- GSK3882347, Nitrofurantoin
- Where
- 15 sites in United States
- Volunteers
- 140 people
- Sponsor
- GlaxoSmithKline
Urinary Tract Infections
Symptomatic Therapy of Uncomplicated Lower Urinary Tract Infections in the Ambulatory Setting.
We propose to perform a randomized controlled patient and assessor blind trial in women between the ages of 18 to 70 years with acute uncomplicated UTI to evaluate initial symptomatic treatment for 3 days with the non-steroidal…
- Trial name
- NCT01039545
- Testing
- Diclofenac, Norfloxacin
- Where
- Switzerland
- Volunteers
- 253 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Urinary Tract Infection
High Strength Cranberry Supplementation for Prevention of Recurrent Urinary Tract Infection
This clinical trial is a Phase 2, multicenter, placebo-controlled, double-blind, parallel-arm study to evaluate the efficacy and safety of High Strength Cranberry (500mg Pacran®) in preventing UTI (cystitis) in women with a…
- Trial name
- NCT03042273
- Testing
- High Strength Cranberry
- Where
- 5 sites in Australia
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Swisse Wellness Pty Ltd
Urinary Tract Infections
An Open-label Trial to Evaluate the Safety of an Essential Oil Infused Perineal Towel
The purpose of this study is to assess the safety (absence of skin irritation) of a feminine hygiene product for perineal hygiene prior to undertaking a clinical effectiveness trial.
- Trial name
- WIPEAWAY (NCT02509403)
- Testing
- Essential oils infused Perineal Hygiene wipe
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alberta
Urinary Schistosomiasis, Schistosoma Haematobium
Efficacy of Bilhvax in Association With Praziquantel for Prevention of Clinical Recurrences of Schistosoma Haematobium
Objectives:To reduce the risk of S. haematobium pathology recurrences during the three years following vaccine administration and to control the safety of this therapeutic strategy in children exposed to urinary schistosomiasis.
- Trial name
- Bilhvax3 (NCT00870649)
- Testing
- Bilhvax vaccine (Sh28GST)
- Where
- Senegal
- Volunteers
- 250 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
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