Clinical trials: Urinary Infections
Urinary Tract Infections
Ertapenem Administered Subcutaneously Versus Intravenously
Infections requiring intravenous antimicrobial therapy are very common events in patients with advanced cancer. Nevertheless, these patients frequently present vascular damages becoming extremely difficult to access and maintain…
- Trial name
- NCT03218800
- Testing
- Ertapenem
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cancer, Brazil
Overactive Bladder (OAB), Urinary Tract Infection (Diagnosis)
Methenamine Hippurate Following Intradetrusor OnabotulinumtoxinA Injection
The goal of this clinical trial is to compare methenamine hippurate prophylaxis to routine antibiotic prophylaxis following onabotulinumtoxinA (BOTOX-A) injections in women with overactive bladder (OAB).
- Trial name
- META (NCT06953271)
- Testing
- Methenamine Hippurate, Typically prescribed oral antibiotic prophylaxis
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Urinary Tract Infections
Study Comparing the DOVER Silver Foley Catheter to a Standard of Care Catheter and a Marketed Silver Coated Foley Catheter
The purpose of the study is to determine if the commercially available device called the DOVER™ Silver Foley catheter prevents infections of the urinary tract.
- Trial name
- NCT00203515
- Testing
- Standard Latex Foley Catheter, Silver Coated Latex Foley Catheter
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Tyco Healthcare Group
Pneumonia - Bacterial, Urinary Tract Infection Bacterial
Clinical Impact of a Machine Learning Decision Support System for Empirical Antibiotic Therapy
The goal of this quasi-experimental study is to analyze if a Machine Learning Clinical Decision Support System can improve the empirical antibiotic treatment in patients with pneumonia, urinary tract infection and / or sepsis.
- Conditions
- Pneumonia - Bacterial, Urinary Tract Infection Bacterial, Bloodstream Infection
- Trial name
- NCT07762378
- Testing
- Machine Learning Decision Support System
- Volunteers
- 486 people
- Sponsor
- Instituto de Investigación Sanitaria Gregorio Marañón
Urinary Catheters, Urinary Tract Infection
Clinical Study on Disposable Sterile Urinary Catheter
This study is a multicenter, randomized controlled study, with the urinary tract infection rate at the time of catheter insertion for 1 week as the primary end point.
- Trial name
- NCT05651217
- Testing
- disposable urinary catheter, super smooth antibacterial urinary catheter
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Shandong Branden Med.Device Co.,Ltd
Kidney Calculi, Urolithiasis
Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS
Retrograde intrarenal surgery (RIRS) is a widely used treatment for kidney stones; however, postoperative infectious complications remain a significant concern.
- Conditions
- Kidney Calculi, Urolithiasis, Urinary Tract Infections
- Trial name
- NCT07655050
- Testing
- Standard Retrograde Intrarenal Surgery, Gentamicin Irrigation, Suction-Enabled Ureteral Access Sheath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Hitit University
Respiratory Tract Infections, Urinary Tract Infections
Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection
In the proposed study, the investigators plan to evaluate the efficacy and safety of Cefotaxime sodium and sulbactam sodium for injection (2:1)for the treatment of respiratory and urinary tract acute bacterial infection under the…
- Trial name
- SWSB (NCT01426191)
- Testing
- xinzhijun
- Volunteers
- 2,032 people
- Sponsor
- Xiangbei Welman Pharmaceutical Co., Ltd
Complicated Urinary Tract Infections
Efficacy and Safety Study of Eravacycline Compared With Ertapenem in Participants With Complicated Urinary Tract Infections
The purpose of this study is to assess the efficacy, safety, and pharmacokinetics of eravacycline compared to ertapenem in treating participants with complicated urinary tract infections (cUTI).
- Trial name
- IGNITE3 (NCT03032510)
- Testing
- Eravacycline, Ertapenem, Levofloxacin
- Where
- 69 sites in United States, Austria and 10 more
- Volunteers
- 1,205 people
- Sponsor
- Tetraphase Pharmaceuticals, Inc
Urinary Tract Infections
EXtended Use of FOsfomycin for the Treatment of CYstitis in Primary Care
Cystitis is the most frequent reason for women to visit their general practitioner. More than 600.000 women suffer from urinary tract infections in The Netherlands each year.
- Trial name
- EXFOCY (NCT05254808)
- Testing
- Fosfomycin, Nitrofurantoin
- Where
- 4 sites in Netherlands
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- MJM Bonten
Urinary Tract Infections
Impact of Sterilization Technique on Incidence of Urinary Tract Infection After Cystoscopy
The purpose of this study is to verify that the incidence rate of urinary tract infections after a routine outpatient cystoscopy is the same for non-sterile (clean) and sterile procedural techniques.
- Trial name
- NCT00177112
- Testing
- clean patient preparation for cystoscopy, sterile patient preparation for cystoscopy
- Where
- United States
- Volunteers
- 275 people
- Sponsor
- University of Minnesota
Asymptomatic Bacteriuria
Safety and Efficacy Study of NVC-422 on Bacteriuria in Catheterized Patients
The purpose of this clinical trial is to study the effects of NVC-422 instilled into the bladder in reducing bacteria in the urine.
- Trial name
- NCT00781339
- Testing
- sodium 2-(dichloroamino)-2-methylpropane-1-sulfonate monohydrate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NovaBay Pharmaceuticals, Inc.
Toileting in Adults With Impaired Functional Status, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status
Quality of Life in Adults Impaired Functioning - A Randomized Controlled Trial of Bidet vs Usual Toileting
Our expectations (hypotheses) are: Primary outcome 1. Regular bidet use will improve quality of life around elimination in adults with impaired functional status.
- Conditions
- Toileting in Adults With Impaired Functional Status, Caregiver Burden for Those Who Care for Adults With Impaired Functional Status, UTI in Adults With Impaired Functional Status
- Trial name
- NCT02042157
- Testing
- Bidet use, Regular toileting
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Stanford University
Recurrent Urinary Tract Infections, Antibiotic Prophylaxis
D Mannose for Prevention and Treatment of RUTIs
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
- Conditions
- Recurrent Urinary Tract Infections, Antibiotic Prophylaxis, Antibiotic Resistance
- Trial name
- mannoseRUTIs (NCT03790254)
- Testing
- systematic review
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Kidney Transplantation, Bacteriuria
A Randomized Control Trial of Antibiotic Treatment Duration For Asymptomatic Bacteriuria After Kidney Transplantation
The major hypothesis to be tested is that there was no difference in the clinical outcome between 7(short-course) and 14(traditional-course) days of antibiotic treatment for asymptomatic bacteriuria early after kidney…
- Conditions
- Kidney Transplantation, Bacteriuria, Asymptomatic Infections
- Trial name
- NCT02575495
- Testing
- 7 days course of antibiotic treatment, 14 days course of antibiotic treatment
- Where
- Thailand
- Volunteers
- 20 people
- Sponsor
- Mahidol University
Recurrent UTIs, Recurrent Urinary Tract Infections
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.
- Conditions
- Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection
- Trial name
- DmannoseRCT (NCT06940622)
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Urinary Tract Infections
Interactions Between Cranberry Juice and Antibiotics Used to Treat Urinary Tract Infections
The purpose of study is to determine whether cranberry juice interacts with antibiotics used to treat urinary tract infections (UTIs).
- Trial name
- NCT00084201
- Testing
- Cranberry juice, Amoxicillin
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Bacterial Infections
Evaluation of the Artificial Intelligence-based Prescription Support Software iAST® for the Choice of Empirical and Semi-targeted Antibiotic Treatment
Inadequate treatment of infections frequently leads to complications that cause new visits to the doctor, lengthen hospital stays and can lead to sepsis, even causing the death of affected patients.
- Trial name
- EVIAST (NCT06174519)
- Testing
- Medical device simulation
- Where
- Spain
- Volunteers
- 325 people
- Sponsor
- Pragmatech AI Solutions
Recurrent Urinary Tract Infection
Treatment of Recurrent Urinary Tract Infection (RUTI) by Traditional Chinese Medicine
Traditional Chinese Medicine (TCM) could be used to treat Recurrent urinary tract infection (RUTI).
- Trial name
- NCT01745328
- Testing
- LVX-AMX, TCM
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Institute of Disease Control and Prevention
Urinary Tract Infection, Pyelonephritis
Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in Children
Cranberry and cranberry-lingonberry juice prevented urinary tract infections in children and in adults in our earlier clinical trials.
- Conditions
- Urinary Tract Infection, Pyelonephritis, Cystitis
- Trial name
- NCT01861353
- Testing
- Cranberry-lingonberry juice
- Where
- Finland
- Volunteers
- 113 people
- Sponsor
- University of Oulu
Urinary Tract Infection
Preventing Urinary Tract Infection Post-Surgery
Approximately 10-27% of patients undergoing gynecologic surgeries develop a catheter associated urinary tract infection (CAUTI) in the post operatory period, as bladder catheterization is a common practice in gynecologic surgery.
- Trial name
- PUPS (NCT01346774)
- Testing
- Cranberry powder capsules
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Betsy Foxman
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