Clinical trials: Urinary Infections
Urinary Tract Infections
Urinary Tract Infections Caused by Extended-spectrum Beta-lactamase-producing Enterobacteria
Urinary tract infections (UTIs) are one of the most common pathologies encountered in general practice. However, with increasing bacterial resistance to antibiotics, their treatment is becoming increasingly complex.
- Trial name
- EBLSE (NCT06910878)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Urinary Tract Infections
Prevention of Renal Failure in Children With Urinary Tract Infections
The aim of the study is to describe the current clinical management of young children with urinary tract infections in Dutch primary care and also to describe the possibilities for improvement and potential cost-efficiency of…
- Trial name
- NCT00316043
- Testing
- Written information for parents, Distance learning package for General Practitioners, Distance learning package for practice assistants
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Radboud University Medical Center
Urinary Tract Infection(UTI), Recurrent Urinary Tract Infections
Emotional Urinary Tract Infection
This project proposes a rigorous investigation into the psychological impact of positive urine culture results and recurrent urinary tract infections (UTIs) in women, with a particular focus on Interstitial Cystitis and Bladder…
- Trial name
- UTI (NCT07191041)
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Northwell Health
Postoperative Urinary Tract Infection, Pelvic Organ Prolapse
Gentamicin Intravesical Efficacy for Infection of Urinary Tract
Urinary tract infection (UTI) is a common problem after surgery for pelvic organ prolapse and stress urinary incontinence. This prospective, randomized, single-masked (subject), two-parallel armed study aims to determine the…
- Conditions
- Postoperative Urinary Tract Infection, Pelvic Organ Prolapse, Stress Urinary Incontinence
- Trial name
- GIVEIT (NCT04246996)
- Testing
- gentamicin sulfate, Catheter clamping only
- Where
- 2 sites in United States
- Volunteers
- 370 people
- Sponsor
- Kaiser Permanente
Febrile Urinary Tract Infection
Individualized Antibiotic Therapy in Children With Acute Uncomplicated Febrile Urinary Tract Infection
An investigator-initiated, open-label, multi-center, randomized, non-inferiority trial of children aged 3 months to 13 years with acute uncomplicated febrile urinary tract infection.
- Trial name
- NCT05301023
- Testing
- Individualized antibiotic therapy, Standard antibiotic therapy
- Where
- 8 sites in Denmark
- Volunteers
- 408 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Urinary Tract Infections
Decreasing Catheter-Associated Urinary Tract Infections in the Pediatric Intensive Care Unit
The purpose of this study is to identify risk factors associated with indwelling urinary catheters, as well as to assess the nurses' knowledge and adherence to hospital policies.
- Trial name
- NCT00672503
- Where
- United States
- Volunteers
- 321 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Recurrent Urinary Tract Infections in Women
Efficacy and Safety of Fecal Microbiota Transfer (FMT) for Recurrent Urinary Tract Infections in Women
Urinary tract infections (UTIs) are highly prevalent worldwide, especially in women, with frequent recurrences and significant healthcare costs.
- Trial name
- NCT07194941
- Testing
- Freeze-dried product made of fresh feces
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Ureterolithiasis, Renal Calculi
An Intelligent Pressure and Temperature Control Ureteral Soft Scope System for Treating Stones With Infection.
The goal of this clinical trial is to determine the efficacy and safety of a novel intelligent pressure and temperature-controlled ureteroscope system for treating renal and upper ureteral stones with concurrent infection.
- Trial name
- NCT06841523
- Testing
- Intelligent Pressure and Temperature-Controlled Ureteroscope System, Conventional Ureteroscope
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Urinary Tract Infections
Clinical Efficacy of Fosfomycin Trometamol Per os in the Treatment of Documented Male Urinary Tract Infections With ESBL-producing Enterobacteriaceae With ESBL Producing Enterobacteriaceae and Resistance Associated With Fluoroquinolones and Cotrimoxazole (FOSF'HOM)
The aim of the study was to evaluate the clinical and microbiological efficacy of fosfomycin trometamol (FT) per os in the treatment of documented male urinary tract infections with ESBL-producing enterobacteriaceae
- Trial name
- FOSF'HOM (NCT03868969)
- Testing
- Fosfomycin Oral Suspension
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Cancer
MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma
RATIONALE: MS-275 may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of MS-275 in treating patients with advanced solid…
- Trial name
- NCT00020579
- Testing
- entinostat
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Urinary Tract Infections, Urinary Tract Infection Lower Acute
The Application of a Novel Urinalysis System (UF-5000) for Reducing Unnecessary Antibiotic Use in Clinical Suspected UTI Patients
Urinary tract infection (UTI) is one of the most common diseases in the population, while antibiotic resistance in UTI has become a critical problem in Hong Kong, with a large proportion of bacteria causing UTI resistant to…
- Trial name
- NCT06918769
- Testing
- Sysmex UF-5000 system, Empirical antibiotics
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- The University of Hong Kong
Urinary Tract Infections, Asymptomatic Bacteriuria
Modified Reporting of Positive Urine Cultures Collected From Long Term Care
Asymptomatic bacteriuria (AB) is a condition in which bacteria are detected in urine culture without urinary symptoms. The inappropriate use of antibiotic treatment for AB selects bacterial flora to express resistance mutations.
- Trial name
- NCT03554603
- Testing
- Modified Report
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Memorial University of Newfoundland
Urinary Tract Infections
COMPARISON OF NITROFURANTOIN WITH FOSFOMYCIN in TREATING CYSTITIS IN WOMEN
Fosfomycin and nitrofurantoin are increasingly being prescribed in outpatients for the oral treatment of urinary tract infection (UTI).
- Trial name
- NCT06518291
- Testing
- Nitrofurantoin 100 MG, Fosfomycin
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Shalamar Institute of Health Sciences
Urinary Tract Infections
A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)
This is a Phase 2 superiority study of LBP-EC01, a recombinant bacteriophage cocktail, with an initial open-label 3-arm pharmacokinetic (PK) lead-in portion of 30 patients to evaluate the optimal dosing regimen to be used in the…
- Trial name
- ELIMINATE (NCT05488340)
- Testing
- LBP-EC01 0.1 x IV dose, LBP-EC01 0.01x IV Dose, LBP-EC01 IV Infusion Dose
- Where
- 17 sites in United States
- Volunteers
- 318 people
- Sponsor
- Locus Biosciences
Thyroid Cancer, Renal Cell Carcinoma
Study of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid Tumors
A multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of nanrilkefusp alfa as monotherapy and in combination with pembrolizumab in patients with selected advanced/metastatic solid tumors
- Conditions
- Thyroid Cancer, Renal Cell Carcinoma, Non Small Cell Lung Cancer, Small-cell Lung Cancer
- Trial name
- NCT04234113
- Testing
- Nanrilkefusp alfa, Pembrolizumab
- Where
- 12 sites in United States, Czechia and 2 more
- Volunteers
- 115 people
- Sponsor
- SOTIO Biotech AG
Pain, Urinary Tract Infections
Evaluate the Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg vs. Placebo
This study will evaluate the safety and efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as a short term analgesic treatment for the primary symptoms of pain or burning when passing urine associated with…
- Trial name
- NCT01064024
- Testing
- Phenazopyridine Hydrochloride
- Where
- United States
- Volunteers
- 233 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Complicated Urinary Tract Infection
Safety and Efficacy of IV CXA-101 and IV Ceftazidime in Patients With Complicated Urinary Tract Infections
The purpose of this study is to evaluate the safety and efficacy of intravenous CXA 101 and comparator in complicated urinary tract infection
- Trial name
- NCT00921024
- Testing
- CXA-101, Ceftazidime
- Where
- 21 sites in United States, Germany and 1 more
- Volunteers
- 129 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Urinary Tract Infection
Bacterial Interference for Prevention of Catheter-Associated UTI: Geriatric Pilot Study
This study is a prospective pilot clinical trial investigating the use of urinary catheters coated with benign E. coli in geriatric subjects.
- Trial name
- NCT00554996
- Testing
- E. coli 83972 coated urinary catheter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Urinary Tract Infection, Bacteriuria
Cranberry Juice for Preventing Bacteria in Urine During Pregnancy
The purpose of this study is to determine the amount of cranberry juice that is most effective in preventing a condition in pregnant women that often leads to urinary tract infections (UTIs).
- Trial name
- NCT00093938
- Testing
- Cranberry juice
- Where
- 2 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Urinary Tract Infections
NextGen - Clinical Implication of Next Generation Sequencing
Recently more advanced techniques, including Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) are available to detect bacteria in urine based on bacterial genomes.
- Trial name
- NCT05206500
- Testing
- Antibiotic, Next Gen
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Wake Forest University Health Sciences
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