Clinical trials: Urinary Infections
Nephrolithiasis, Urinary Tract Infections
A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL])
When patients are going to have surgery to remove large kidney stones (percutaneous nephrolithotomy [PCNL]), it is not clear whether the patients benefit from a course of prophylactic preoperative oral antibiotics; currently both…
- Trial name
- NCT02384200
- Testing
- nitrofurantoin monohydrate/macrocrystalline capsules, ampicillin, gentamicin
- Where
- 8 sites in United States, Canada
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Urinary Tract Infections
Preventing Recurrent Urinary Tract Infections With α-D-mannose
In this trial, women with history of recurrent urinary tract infections (UTIs) will be followed over the course of 6 months. The women will be randomized either to D- Mannose or Placebo.
- Trial name
- PUTIM (NCT03497598)
- Testing
- Mannose, Lactose
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Kantonsspital Aarau
Urinary Tract Infection
Temocillin Use in Complicated Urinary Tract Infections Due to Extended Spectrum Beta-Lactamases (ESBL)/AmpC Enterobacteriaceae
This study is aimed at demonstrating the efficacy of temocillin in the treatment of complicated Urinary Tract Infection (UTI) due to confirmed Extended Spectrum Beta-Lactamases (ESBL) producing or AmpC hyperproducing…
- Trial name
- TEA (NCT01543347)
- Testing
- Temocillin
- Where
- United Kingdom
- Sponsor
- Belpharma s.a.
Hypospadias
Antibiotic Use in Distal Hypospadias Repair
Hypospadias is a common condition where the opening of the penis is not located at the tip, but along the underside of the penis. It is estimated to occur in 1/300 live male births, making it one of the most common birth defects.
- Trial name
- NCT03275519
- Testing
- Randomization to not receive prophylactic antibiotics after surgery., Randomization to receive prophylactic antibiotics after surgery
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Urinary Tract Infection
Cefpodoxime vs Ciprofloxacin for Acute Cystitis
Urinary tract infection (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20s.
- Trial name
- NCT00194532
- Testing
- Cefpodoxime, Ciprofloxacin
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Urinary Tract Infection
Efficacy Study of Antimicrobial Catheters to Avoid Urinary Infections in Spinal Cord Injured Patients
The purpose of this trial is to make a comparison between the use of antiseptic silver alloy-coated silicone urinary catheters and the use of conventional silicone urinary catheters in spinal cord injured patients to prevent…
- Trial name
- ESCALE (NCT01803919)
- Testing
- Silver Alloy-Coated Urinary Catheters, Conventional Urinary Catheter
- Where
- 20 sites in Chile, Italy and 3 more
- Volunteers
- 489 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Ureter Stone, Renal Stone
Duration Between Drainage and Ureteroscopic Lithotripsy
This study will be conducted to compare early (seven days) versus delayed (14-21 days) definitive ureteroscopic lithotripsy after initial drainage for obstructing ureteral or renal stones associated with infection.
- Conditions
- Ureter Stone, Renal Stone, Ureteric Obstruction
- Trial name
- NCT06101563
- Testing
- Early ureteroscopy, Delayed Ureteroscopy
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Quality of Life, Catheter-Associated Urinary Tract Infection
Evaluation of Quality-of-Life Improvements Using UroShield Device
The goal of this pilot study is to test key elements of the full study that will follow, including recruitment and retention strategies, intervention delivery, laboratory testing, data collection methods, and adherence to study…
- Trial name
- NCT06319352
- Testing
- Active UroShield
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus, Type 2
Post-authorization Safety Study in Type 2 Diabetic Patients in Saudi Arabia Treated With Empagliflozin to Assess the Incidence of Ketoacidosis, Severe Complications of Urinary Tract Infection, Volume Depletion, and Dehydration
The objectives of this study are to assess the risk of ketoacidosis, severe urinary tract infections, volume depletion, and dehydration associated in patients with T2DM initiating Empagliflozin compared to patient initiating a…
- Trial name
- NCT03764631
- Testing
- Empagliflozin, Dipeptidyl-peptidase 4 (DPP-4) inhibitors
- Where
- 21 sites in Saudi Arabia
- Volunteers
- 1,502 people
- Sponsor
- Boehringer Ingelheim
Urinary Tract Infections, Kidney Transplant Rejection
PRObiotics for KIdney Transplantation
The goal of this clinical trial is to assess if dietary supplememtation with OMNi-BiOTiC® 41167 reduces the risk of urinary tract infections in kidney transplant recipients.
- Conditions
- Urinary Tract Infections, Kidney Transplant Rejection, Kidney Transplant Infection, Dysbiosis
- Trial name
- ProKiT (NCT06825117)
- Testing
- OMNi-BiOTiC® 41167
- Where
- Italy
- Volunteers
- 132 people
- Sponsor
- University Hospital, Udine, Italy
Uncomplicated Urinary Tract Infections
A Study to Investigate Pivmecillinam Versus Nitrofurantoin in Female Adolescents 12 to Less Than 18 Years of Age With Uncomplicated Urinary Tract Infection
Multicenter, Randomized, Open-label, Active-controlled Study with Blinded Assessor to Evaluate the Safety and Tolerability of Pivmecillinam Hydrochloride versus Nitrofurantoin for the Treatment of Female Pediatric Subjects, 12…
- Trial name
- NCT07871968
- Testing
- Pivya (Pivmecillinam 185 mg), Nitrofurantoin 100 mg (nitrofurantoin monohydrate/macrocrystalline capsule)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Alembic Therapeutics
Urinary Retention, Catheter-Associated Urinary Tract Infection
Effectiveness and Cost-effectiveness of the T-Control® Catheter in Patients With Acute Urine Retention
The general purpose of this study is to assess the preliminary effectiveness and cost-effectiveness of the T-Control® catheter versus the Foley type catheter in patients with Acute Urine Retention.
- Conditions
- Urinary Retention, Catheter-Associated Urinary Tract Infection, Catheter Complications
- Trial name
- NCT05643950
- Testing
- Foley catheter, T-Control catheter
- Where
- 2 sites in Spain
- Sponsor
- Rethink Medical SL
Stress Urinary Incontinence
Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study)
The primary aim of this study is to assess the utility of prophylactic oral antibiotics at time of Bulkamid transurethral bulking to reduce the incidence of urinary tract infection (UTI) in the immediate postoperative period.
- Trial name
- NCT06706362
- Testing
- Bactrim or Macrobid
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Pneumonia, Heart Failure
Hospitalization at Home: The Acute Care Home Hospital Program for Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Pneumonia, Heart Failure, Cellulitis, Urinary Tract Infections
- Trial name
- NCT02864420
- Testing
- Home hospitalization, Inpatient Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Brigham and Women's Hospital
Uncomplicated Urinary Tract Infection, Cystitis
Oral Omadacycline vs. Oral Nitrofurantoin for the Treatment of Cystitis
The purpose of this study is to evaluate the safety and efficacy of oral omadacycline as compared to oral nitrofurantoin in the treatment of female adults with cystitis.
- Trial name
- NCT03425396
- Testing
- Omadacycline tablets, Nitrofurantoin capsules
- Where
- 23 sites in United States
- Volunteers
- 225 people
- Sponsor
- Paratek Pharmaceuticals Inc
Urinary Infection
The Painful Real-life Experience of the Child of Less Than Three Years During the Removal of the Collecting Bags in the Pediatric Urgency: What Strategy of Coverage?
Urinary infection is one of the most common bacterial infections in pediatrics and requires urine collections to be diagnosed. In France, among children under 3, urine samples are collected thanks to collecting bags.
- Trial name
- LINIPOCHE (NCT01659190)
- Testing
- Oiled-limestone liniment
- Where
- France
- Volunteers
- 136 people
- Sponsor
- University Hospital, Limoges
Acute Male Urinary Tract Infection
Antibiotic Treatment for 7 Days Versus 14 Days in Patients With Acute Male Urinary Tract Infection
This study will investigate the treatment of urinary tract infection (UTI) in men. The investigators are looking to see if shorter duration of antibiotics (7 days) is not inferior to a longer duration of antibiotics (14 days).
- Trial name
- PROSTASHORT (NCT02424461)
- Testing
- Ceftriaxone, Ofloxacine
- Where
- France
- Volunteers
- 274 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urinary Tract Infection
Diagnosis of Subclinical Urinary Tract Infections Using Advanced Microbiome Survey Techniques in High Risk Trauma Patients
The purpose of this study is to see if the investigators can identify early those patients who are admitted to the hospital and have a urinary tract infection (UTI) or those patients that develop a UTI during their…
- Trial name
- NCT01834391
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- Mayo Clinic
Urinary Catheter
Catheter in the Prevention of Urinary Tract Infections and Crystallization Study(CPUTICS)
This is a single-center randomized controlled trial in comparison of Parylene-Coated versus Silicone Catheters in the Prevention of Urinary Tract Infections and Crystallization.
- Trial name
- NCT06230042
- Testing
- Types of catheters
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Shanghai East Hospital
Infections, Bacterial
Pharmacokinetic Study of Oral Gepotidacin (GSK2140944) in Subjects With Uncomplicated Urinary Tract Infection (Acute Cystitis)
Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor that is being developed for the treatment of uncomplicated urinary tract infections (UTIs; acute cystitis).
- Trial name
- NCT03568942
- Testing
- Gepotidacin
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- GlaxoSmithKline
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