Clinical trials: Urinary Sodium Excretion
Psychological Stress, Hypertension, Renal
Effects of an Immunosuppressant Mycophenolate Mofetil or MMF on the Urinary Sodium Excretion Response to Mental Stress
The purpose of this study is to determine if stopping the stress induced increase in inflammation will prevent sodium retention which in turn increases blood pressure. Each subject will test two separate times.
- Trial name
- MMF (NCT02432339)
- Testing
- mycophenolate mofetil (MMF)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augusta University
Polycystic Kidney, Autosomal Dominant
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
The aim of the study is to test the following hypotheses: 1. that the function and/or regulation of AQP2 and /or ENaC in the principal cells is abnormal in autosomal dominant polycystic kidney disease. 2.
- Trial name
- NCT00410007
- Testing
- High Sodium Diet, Low Sodium Diet, Hypertonic saline infusion
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Carolina Cannillo
Heart Failure
Acetazolamide and Spironolactone to Increase Natriuresis in Congestive Heart Failure
This study has two primary objectives: 1. To compare combination therapy with acetazolamide and low-dose loop diuretics versus high-dose loop diuretics (standard of care) in patients with acute decompensated heart failure at high…
- Trial name
- DIURESIS-CHF (NCT01973335)
- Testing
- Combination therapy with acetazolamide and low-dose loop diuretics, High-dose loop diuretics, Upfront therapy with oral spironolactone
- Where
- 2 sites in Belgium
- Volunteers
- 34 people
- Sponsor
- Hasselt University
Essential Hypertension and Healthy Controls
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension
The aim of the study is to test the following hypotheses: that the function and/or regulation of AQP2 and/or ENaC in the principal cells is abnormal in essential hypertension.
- Trial name
- NCT00345124
- Testing
- high sodium diet, Low Sodium Diet
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Asymptomatic Hyperuricemia
A Study to Assess the Effect of Intensive Uric Acid (UA) Lowering Therapy With RDEA3170, Febuxostat, Dapagliflozin on Urinary Excretion of UA
This is a randomized, placebo controlled, double-blind, 2-way crossover study conducted on asymptomatic hyperuricemic patients. The core study consists of screening period, 2 treatment periods (verinurad + febuxostat +…
- Trial name
- NCT03316131
- Testing
- Verinurad, Febuxostat, Dapagliflozin
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- AstraZeneca
Postural Tachycardia Syndrome, Orthostatic Intolerance
Peripheral Dopamine in Postural Tachycardia Syndrome
The purpose of the proposed research is to determine how changes in kidney dopamine (DA) activity influence urinary sodium excretion.
- Trial name
- NCT00685919
- Testing
- Carbidopa
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Salt; Deficit (or Low), Cystic Fibrosis
Evaluation of Salt Status in Patients With Cystic Fibrosis
The results of the annual check-up will be collected to evaluate the best urinary marker for fractional sodium excretion and salt status will be correlated to clinical outcome measures.
- Trial name
- NCT04556162
- Testing
- fractional sodium excretion, risk subgroups
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- University Hospital, Ghent
Dietary Habits, Risk Factor, Cardiovascular
Sodium Intake in Ecuadorian Population
This study is aim to determine the sodium intake in Ecuadorian population that is an unknown information at present. For that, 24h urine samples will be collected from 130 subjects working either at tue USFQ or HDLV to measure…
- Conditions
- Dietary Habits, Risk Factor, Cardiovascular, Nutritional Disorder
- Trial name
- NCT03154502
- Testing
- Urinary sodium excretion
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
Salt; Excess, Hypertension
Study With an Innovative Equipment to Monitor and Control SALT During Cooking
In this study, the researchers will evaluate the efficacy of an intervention using the SALT CONTROL H instrument (an innovative equipment to monitor and control salt) in workers at the University of Porto to reduce dietary salt…
- Trial name
- iMC_SALT (NCT03974477)
- Testing
- SALT CONTROL H equipment to control and monitor salt during cooking process
- Where
- Portugal
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto