Clinical trials: Urinary Stones
Kidney Stone
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones
Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation.
- Trial name
- ENORC (NCT03657667)
- Testing
- Ureteroscopy
- Where
- 9 sites in United States, Canada
- Volunteers
- 43 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Ureteric Stone
to Compare the Effectiveness of Thulium Fiber Laser and Holmium YAG Laser for Ureteroscopic Lithotripsy
This prospective randomized clinical trial aimed to compare the difference in stone ablation rates of TFL and Ho:YAG laser in a clinical setting.
- Trial name
- NCT05218057
- Testing
- Ureteroscopic lithotripsy
- Where
- Hong Kong
- Volunteers
- 46 people
- Sponsor
- Chinese University of Hong Kong
Renal Stones
Standard Versus Mini Percutaneous Nephrolithotomy for Renal Stones
Renal stone disease is a common urological condition associated with significant morbidity. Percutaneous nephrolithotomy (PCNL) is the standard treatment for renal stones larger than 2 cm.
- Trial name
- NCT07464717
- Testing
- Mini Percutaneous Nephrolithotomy, Standard Percutaneous Nephrolithotomy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Renal Calculi
Tip-flexible Semi-rigid Ureterorenoscope Versus Flexible Ureteroscopy in Renal Calculi
This study evaluates the safety and efficacy of the novel tip-flexible semi-rigid ureterorenoscope for the treatment of renal calculi using a prospective, randomized multicentre trial design.
- Trial name
- NCT02426931
- Testing
- the tip-flexible ureterorenoscope, the classic flexible ureteroscope
- Volunteers
- 280 people
- Sponsor
- Ling Li, MD
Kidney Calculi, Kidney Stone
Are the Stone Density and Location Useful Parameters for Small Kidney Stones?
The investigators aimed to evaluate whether these parameters could be guides for us in the selection of RIRS or Mini-PNL procedures in kidney stones that are smaller than 2 cm.
- Trial name
- NCT03503539
- Testing
- Mini percutaneous nephrolithotomy, Retrograde intrarenal surgery
- Volunteers
- 60 people
- Sponsor
- Abant Izzet Baysal University
Stone, Kidney, Stone Ureter
Stent Omission After Ureteroscopy and Lithotripsy in the Michigan Urological Surgery Improvement Collaborative
This is a multicenter prospective trial with randomized and observational cohorts assessing patient-reported outcomes and unplanned healthcare utilization following ureteroscopic treatment of renal and ureteral stones, with…
- Trial name
- NCT05866081
- Testing
- Standard of care stent placement, No stent placement, Surveys
- Where
- 16 sites in United States
- Volunteers
- 792 people
- Sponsor
- University of Michigan
Kidney Calculi, Ureter Calculi
Naftopidil 75mg for Improving Clearance of Urinary Stones
The purpose of this study is to evaluate Efficacy and Safety of oral intake of Naftopidil 75mg once daily for the improving clearance of ureteral or renal stones.
- Trial name
- NCT02011737
- Testing
- naftopidil 75mg
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Samsung Medical Center
Kidney Calculi
Remifentanil in Extracorporeal Shock Wave Lithotripsy
The purpose of this study is to compare the analgesic efficacy and side effects induced by administration of two different infusion rates of remifentanil, 0,05 mcg/ Kg/ min versus 0,1mcg/ Kg/ min, in order to determine which one…
- Trial name
- ESWL (NCT01452880)
- Testing
- Remifentanil
- Where
- Italy
- Volunteers
- 228 people
- Sponsor
- University of Roma La Sapienza
Urolithiasis
The Use of Direct Puncture Technique With Mini-PCNL
A single-center randomized study to evaluate the safety and effectiveness of direct puncture of the caliceal system in mini-percutaneous nephrolithotripsy. 60 patients Inclusion criteria: 1.
- Trial name
- NCT04610840
- Testing
- Puncture of the caliceal system
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Nephrolithiasis, Urosepsis
Serum Endotoxin Assay to Predict the Development of Postoperative Infectious Complications and Systemic Inflammatory Response Following Percutaneous Nephrolithotomy.
The aim of the study is to establish an infectious risk stratification system based on pre-and post-operative blood endotoxin profile.
- Trial name
- NCT04669886
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Nephrolithiasis, Ureteral Calculi
The Efficacy of Tamsulosin in the Treatment of Ureteral Stones in Emergency Department Patients
The purpose of this study is to determine the efficacy of the α-adrenergic antagonist tamsulosin in the treatment of adult emergency department (ED) patients with ureteral colic secondary to lower ureteral calculus.
- Trial name
- NCT00600405
- Testing
- tamsulosin, Standard therapy with ibuprofen and oxycodone.
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- MaineHealth
Periodontal Diseases, Nephrolithiasis
The Association Between Nephrolithiasis and Periodontal Status
Dental calculus is a calcified deposits firmly attached to teeth and implants surfaces. Dental calculus is strongly associated with periodontitis and considered to have indirect role in the pathogenesis of periodontal diseases.
- Trial name
- NCT03102086
- Testing
- Scaling
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Urolithiasis, Urinary Tract Stones
Detection of Urinary Stones on ULDCT With Deep-learning Image Reconstruction Algorithm
Urolithiasis has an increasing incidence and prevalence worldwide, and some patients may have multiple recurrences. Because these stone-related episodes may lead to multiple diagnostic examinations requiring ionizing radiation…
- Conditions
- Urolithiasis, Urinary Tract Stones, Renal Colic, Deep Learning Reconstruction
- Trial name
- URO DLIR (NCT04490343)
- Testing
- Abdominopelvic low dose CT
- Where
- France
- Volunteers
- 62 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Urolithiasis, Airway Management
Videolaryngoscope vs VideoLMA for Endotracheal Intubation in RIRS
This study is a prospective, randomized, parallel-group clinical trial comparing videolaryngoscope and videoLMA for endotracheal intubation in adult patients undergoing surgery. Patients will be randomly assigned into two groups.
- Trial name
- NCT07555535
- Testing
- Videolaryngoscope, VideoLMA
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ela Erdem Hıdiroglu
Ureteral Calculi
Comparison of Laryngeal Masks in Urethral Cystoscopic Surgery Operations: a Prospective Randomized Clinical Study
The use of Laryngeal masks are increased.This study aimed to compare lma pro seal and baska -mask in urethral retrograde sistoscopy operations.
- Trial name
- NCT04186455
- Testing
- proseal, baska-mask
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kocaeli University
Kidney Stone
A Novel Method for Retrograde Intrarenal Surgery (RIRS)
In this prospective randomised controlled study, investigators aims to evaluate the effect of 80 mg gentamicin added to 3 liters of irrigation fluid on stone free rate, intraoperative and postoperative complications during RIRS…
- Trial name
- NCT05202158
- Testing
- Addition of gentamicin to irrigation fluid during RIRS, Only irrigation fluid during RIRS
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Ankara Training and Research Hospital
Renal Stones, Retrograde Intrarenal Surgery
Safety of Thulium Fiber Laser Litothripsy in the Management of Large Renal Stones (>1000 mm³) and Factors Affecting Treatment Success
The aim of this study is to compare the efficacy and safety of Thulium Fiber Laser (TFL) litothripsy according to stone density and the factors affecting success in patients undergoing retrograde intrarenal surgery (RIRS) for…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Thulium Fiber Laser
- Trial name
- RIRS and TFL (NCT07153978)
- Testing
- Effectivity of TFL on large renal stone
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Muharrem Baturu
Urolithiasis
F-URS and Mini PCNL for Pediatric Urolithiasis
To compare RIRS versus mini-perc PNL in the management of medium size pediatric renal stones (10-20 mm) through a RCT.
- Trial name
- NCT06571617
- Testing
- Mini PCNL (mini percutaneous nephrolithotomy), RIRS (retrograde intrarenal surgery/ flexible URS)
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Nephrolithiasis, Low Urine Volume
Hidrate Me Smart Water Bottle Use in Patient With Nephrolithiasis
The primary objective of this study would be to determine whether utilization of this technology improves adherence to recommended increases in hydration for stone forming patients with low urine volume relative to standard…
- Trial name
- HidrateMe (NCT02938884)
- Testing
- HidrateSpark Water Bottle
- Where
- 4 sites in United States
- Volunteers
- 85 people
- Sponsor
- University of Minnesota
Renal Colic, Urolithiasis
Sterile Water Injection vs Morphine for Renal Colic
This study aims to compare intradermal sterile water injections (ISWI) with intravenous morphine for pain relief in adults with acute renal colic caused by urinary stones.
- Trial name
- ISWI-Morph (NCT07378904)
- Testing
- Single Intradermal Sterile Water Injection, Multiple Intradermal Sterile Water Injections, Intravenous Morphine
- Where
- Tunisia
- Volunteers
- 150 people
- Sponsor
- University Tunis El Manar