Clinical trials: Urinary Stress Incontinence
Stress Urinary Incontinence, Vaginal Prolapse
BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)
The goal of this clinical trial is to learn if retropubic midurethral sling (RP-MUS) or bulkamide injection (PAHG) at the time of pelvic organ prolapse repair is better from the patient's perspective.
- Trial name
- BELIEVE (NCT06754046)
- Testing
- RP-MUS, PAHG
- Where
- United States
- Volunteers
- 476 people
- Sponsor
- University Hospitals Cleveland Medical Center
Stress Urinary Incontinence
Patient-reported Outcome After Sling Insertion Using the Incontinence Outcome Questionnaire (IOQ)
Midurethral tapes are by now standard procedure in the surgical treatment of women with stress urinary incontinence. While the retropubic TVT is well documented with long-term results up to 11 years and continence rates of 90 %…
- Trial name
- NCT01042275
- Where
- Switzerland
- Volunteers
- 628 people
- Sponsor
- University of Zurich
Urinary Incontinence Mixed (Stress and Urge)
Efficacy of a Combined Surgical and Pharmacological Therapy to Treat Mixed Urinary Incontinence.
The purpose of this study is to determine in female patients who suffer mixed urinary incontinence (MUI) the following: 1) the proportion of patients that are cured or improved by a single modality therapy (drug or surgery…
- Trial name
- NCT01899794
- Testing
- TVT-O/Oxytrol, TVT-O, Oxytrol
- Volunteers
- 66 people
- Sponsor
- Jewish General Hospital
Women With Stress Urinary Incontinence
Therapeutic Efficacy in Women With Stress Urinary Incontinence
We will get the impact of duloxetine versus imipramine on therapeutic efficacy in women with SUI.
- Trial name
- NCT05677295
- Testing
- duloxetine, Imipramine
- Where
- Taiwan
- Volunteers
- 90 people
- Sponsor
- Far Eastern Memorial Hospital
Stress Urinary Incontinence, Urethral Sling Surgery
Trial Comparing Mini-Arc Precise Pro and the Trans Vaginal Obturator Tape for Stress Urinary Incontinence
Randomized comparison of two surgeries for the treatment of female stress urinary incontinence.
- Trial name
- NCT01799122
- Testing
- Mini Arc Precise Pro and Trans vaginal obturator sling (TVT-0)
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Stress Urinary Incontinence
The Impact of Retropubic Lidocaine vs Saline on Postoperative Urinary Retention Following Midurethral Sling
Stress urinary incontinence affects millions of women worldwide and has a profound impact on the quality of life of older individuals, their subjective health status, levels of depression and need for care.
- Trial name
- NCT03913845
- Testing
- lidocaine with epinephrine, Normal saline with epinephrine
- Where
- 4 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- West Penn Allegheny Health System
Osteoporosis, Postmenopausal
Stress Urinary Incontinence and Sarcopenia in Postmenopausal Osteoporosis
The primary aim of our study is to evaluate the presence of stress urinary incontinence in postmenopausal patients with and without osteoporosis, determine its impact on quality of life, and explore its relationship with…
- Trial name
- NCT06655701
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beylikduzu State Hospital
Urinary Stress Incontinence, Treatment
Bulkamid Treatment of Stress Incontinence in Women With Urinary Stress Incontinence and Not Suitable to TVT-procedure
The aim of this prospective, randomized study of Bulkamid treatment is to investigate the efficacy of Bulkamid treatment in women with urinary stress incontinence not suitable to TVT-procedure because of suspected ISD.
- Trial name
- NCT00984958
- Testing
- Bulkamid, Bulkamid expectation
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Skaraborg Hospital
Stress Urinary Incontinence
The Valsalva Urethral Profile : a Measure to Assess Stress Urinary Incontinence
Clinical and paraclinical appraisal of stress urinary incontinence (SUI) is mainly based on the assessment of pelvic floor muscles (PFM) contraction and urethral mobility, the measurement of the maximum urethral closure pressure…
- Trial name
- NCT04311814
- Testing
- Maximum urethral closure pressure during Valsalva (v-MUCP)
- Volunteers
- 695 people, healthy volunteers welcome
- Sponsor
- Poissy-Saint Germain Hospital
Stress Urinary Incontinence, Postoperative Urinary Tract Infection
The Effectiveness of Prophylactic Antibiotics for Urethral Bulking
The goal of this clinical trial is to evaluate if prophylactic antibiotics in urethral bulking are effective in reducing postprocedural urinary tract infections.
- Conditions
- Stress Urinary Incontinence, Postoperative Urinary Tract Infection, Urethral Bulking
- Trial name
- NCT06261736
- Testing
- Prophylactic antibiotics, No antibiotics
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Atlantic Health System
Urinary Tract Infections, Stress Urinary Incontinence
Prophylactic Antibiotics for Outpatient Urethral Bulking
The purpose of this study is to evaluate whether taking prophylactic (preventative) antibiotics at the time of standard of care clinic-based urethral bulking reduces the risk of post-procedural urinary tract infection (UTI).
- Conditions
- Urinary Tract Infections, Stress Urinary Incontinence, Urinary Incontinence
- Trial name
- NCT07501065
- Testing
- Bactrim (800/160 mg), Keflex (500 mg), Cipro (250 mg), or Macrobid (100mg)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Stress Incontinence Female, Pelvic Organ Prolapse
Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy
This study looks at the best time to place a midurethral sling (MUS), which is a small piece of mesh used to treat stress urinary incontinence (SUI) (leaking urine when you cough, laugh, or exercise).
- Trial name
- NCT07008898
- Testing
- Midurethral sling placed before robotic sacrocolpopexy, Midurethral sling placed after robotic sacrocolpopexy
- Where
- 2 sites in United States
- Volunteers
- 110 people
- Sponsor
- University of Alabama at Birmingham
Urinary Incontinence, Stress, Urinary Incontinence, Urge
French Study to Evaluate the Impact of a Cognitive Therapy on Urinary Incontinent Women of All Age's Perineal Settings.
This trial is a pathophysiological study evaluating the impact of a cognitive therapy on the perineal neuromuscular mechanisms in women patients with urinary incontinence.
- Trial name
- NCT03797365
- Testing
- Classical rehabilitation, Cognitive associated rehabilitation
- Volunteers
- 40 people
- Sponsor
- Pierre and Marie Curie University
Pelvic Organ Prolapse, Stress Urinary Incontinence
Outcomes of Pelvic Surgery With and Without Anti-incontinence Procedure in Occult Stress Urinary Incontinence Patients
1. To evaluate whether a standardized tension-free vaginal tape-obturator(TVT-O) procedure, when added to a planned improved reconstruction pelvic surgery, improves the rate of urinary stress continence in subjects with occult…
- Conditions
- Pelvic Organ Prolapse, Stress Urinary Incontinence, Other Specified Urinary Incontinence
- Trial name
- PTOS (NCT02193607)
- Testing
- TVT-O, Improved reconstruction pelvic surgery
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Peking Union Medical College Hospital
Stress Urinary Incontinence
Neuromuscular Re-eduaction, Exercise and Electric Dry Needling vs. Neuromuscular Re-education and Exercise for Stress Urinary Incontinence
The purpose of this research is to compare two different approaches for treating patients with stress urinary incontinence: neuromuscular re-education, impairment-based exercise and electric dry needling versus neuromuscular…
- Trial name
- NCT03238716
- Testing
- Electric DN, NM Re-ed, Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Alabama Physical Therapy & Acupuncture
Stress Urinary Incontinence, Vulvovaginal Signs and Symptoms
Clinical Evaluation of Fractional Bi-Polar RF for Symptoms of SUI and Vulvovaginal Atrophy
Clinical Evaluation of Fractional Bi-Polar Radio-Frequency for Symptoms of Stress Urinary Incontinence and Vulvovaginal Atrophy
- Trial name
- NCT04705571
- Testing
- MorpheusV Applicator
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- InMode MD Ltd.
Urinary Incontinence
Stem Cells Tratment for the Local Feminine Stress Urinary Incontinence Treatment (HULPURO)
Evaluate the feasability and security of the autologous ASC for the femenine stress urinary incontinence
- Trial name
- HULPURO (NCT01804153)
- Testing
- Adipose-derived expanded stem cells
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Urinary Incontinence
Platelet Rich Plasma (PRP) and High Intensity Focused Ultrasound (HIFU) in Management of Stress Urinary Incontinence (SUI): Pilot Study
Previous studies Results show (PRP) is safe and effective in treating SUI, other studies show the result of energy base devices (Co2 laser, HIFU) are effective in treating of SUI .
- Trial name
- NCT06691334
- Testing
- PRP injection, Hifu procedure and PRP injection
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Urinary Bladder, Overactive
Evaluating the Change of Overactive Bladder Symptoms in Women Post Pubovaginal Sling Procedure for Stress Incontinence
Pubovaginal sling (PVS) procedures are designed to curtail bladder leakage brought about by strenuous events such as child birth.
- Trial name
- NCT01194999
- Testing
- Pubovaginal sling procedure
- Where
- Canada
- Volunteers
- 132 people
- Sponsor
- Barrie Urology Associates
Stress Urinary Incontinence
Virtue® Male Sling Fixation Study
This study is a multi-center study that will assess the efficacy and safety of suture fixation of the Virtue® Male Sling.
- Trial name
- NCT01170728
- Testing
- Coloplast Virtue® Male Sling
- Where
- 10 sites in United States
- Volunteers
- 44 people
- Sponsor
- Coloplast A/S