Clinical trials: Urinary Symptoms
Chronic Kidney Disease, Overactive Bladder
Urinary Function and Multimorbidity Risks: A Longitudinal Study in Beijing Community-Dwelling Elderly
This study focuses on Beijing community residents aged 60 and above, aiming to understand how urinary function (like bladder or kidney function) and multiple health problems (such as high blood pressure, diabetes) affect each…
- Conditions
- Chronic Kidney Disease, Overactive Bladder, Benign Prostatic Hyperplasia, Female Pelvic Floor Dysfunction
- Trial name
- UFMR-BE (NCT07357714)
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Lower Urinary Tract Symptoms (LUTS), Transition Care
Study of Transition in Real-life Experiences Affecting Micturition and Well-being in Adolescent Years
With this study, we would like to interview 16-25-year-olds who have experienced urinary problems since childhood and who are still experiencing symptoms in young adulthood.
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Transition Care, Enuresis Nocturnal, Adverse Childhood Experiences
- Trial name
- STREAMWAY (NCT07339865)
- Testing
- Semi-structured in-depth interviews with standardized validated questionnaires, Completion of a urological time-line
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Lower Urinary Tract Symptoms, Prostatic Hyperplasia
Efficacy and Safety of Longidaze in the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia
The goal of this clinical trial is to learn if Longidaze works to treat lower urinary tract symptoms in adult males with benign prostatic hyperplasia. It will also learn about the safety of Longidaze.
- Trial name
- ADAM (NCT06568718)
- Testing
- bovhyaluronidase azoximer, tamsulosin
- Where
- 3 sites in Russia
- Volunteers
- 229 people
- Sponsor
- NPO Petrovax
Lower Urinary Tract Symptoms, Prostate Obstruction
Intermittent vs Daily Tamsulosin for LUTS/BPH
Background: Lower urinary tract symptoms (LUTS) are common in aging men, most often due to benign prostatic hyperplasia (BPH), and significantly impair quality of life.
- Trial name
- ARAB (NCT07308002)
- Testing
- Daily Tamsulosin, Intermittent Tamsulosin
- Where
- Egypt
- Volunteers
- 288 people
- Sponsor
- Mansoura University
Multiple Sclerosis, Lower Urinary Tract Symptoms
Transcutaneous Tibial Neuro-stimulation to Improve Voiding Dysfunction in Multiple Sclerosis.
The present trial is designed to assess the efficacy and safety of transcutaneous tibial neuro-stimulation (TTNS) in improving bladder emptying in multiple sclerosis (MS) patients.
- Trial name
- NEUROSTIM-SEP1 (NCT04573673)
- Testing
- PTNS de verum
- Where
- France
- Volunteers
- 68 people
- Sponsor
- University Hospital, Lille
Acute Urinary Retention, LUTS(Lower Urinary Tract Symptoms)
Perioperative Tamsulosin for Treating Voiding Dysfunction Following Prostate Biopsy
The goal of this clinical trial is to learn if the drug Tamsulosin Hydrochloride works to treat urination difficulties after a prostate biopsy in men.The main questions it aims to answer are: Does Tamsulosin Hydrochloride lower…
- Trial name
- NCT07276919
- Testing
- Tamsulosin 0.2mg
- Where
- China
- Volunteers
- 1,844 people
- Sponsor
- Peking University First Hospital
Lower Urinary Tract Symptoms, BPH
US Imaging for the Assessment of LUTS
The purpose of this research is to develop an ultrasound (US) based urodynamics (UDS) evaluation of voiding based on successful magnetic resonance imaging (MRI)-UDS evaluation.
- Trial name
- NCT06323109
- Testing
- MRI-UDS; US-UDS; MCUD
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
BPH (Benign Prostatic Hyperplasia), Lower Urinary Tract Symptoms
RT-310 Dose Escalation BPH Study
RT-310, a novel implant, is intended to minimally invasive treat locally the prostate gland for the management of prostate disease, while minimizing side-effects.
- Trial name
- NCT06136819
- Testing
- RT-310
- Where
- 4 sites in Australia, New Zealand
- Volunteers
- 20 people
- Sponsor
- Resurge Therapeutics Inc.
Benign Prostatic Hyperplasia, Prostate Hyperplasia
5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy
The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride.
- Conditions
- Benign Prostatic Hyperplasia, Prostate Hyperplasia, Prostate Disease, Prostate Hypertrophy
- Trial name
- NCT04288427
- Testing
- Finasteride
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Beth Israel Deaconess Medical Center
Lower Urinary Tract Symptoms
Status of Disease Burden of Lower Urinary Tract Symptoms in Chinese Male Community
This study, set up as a cross-sectional survey, seeks to delve into the disease burden and the demographic specifics of lower urinary tract symptoms (LUTS) among the male community in China.
- Trial name
- NCT06352736
- Where
- China
- Volunteers
- 12,567 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Cystitis, Recurrent, Urinary Tract Infections
Microbiome-Modulating Prophylaxis RCT: Antibiotic vs Gynoflor in Postmenopausal Women With Recurrent Cystitis
This open-label, parallel-group randomized controlled trial compares two prophylaxis strategies for recurrent urinary tract infection (rUTI) in postmenopausal women: (1) nightly oral nitrofurantoin 100 mg for 6 months versus (2)…
- Trial name
- microbiome (NCT07186465)
- Testing
- Nitrofurantoin, Gynoflor
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Mahidol University
Lower Urinary Tract Symptoms, Stress Urinary Incontinence
Pelvic Floor Disorder Symptoms in Women Seeking Weight Loss Therapy
The purpose of this study is to compare change in pelvic floor symptoms between patients receiving medical therapy for weight loss and surgical treatment for weight loss.
- Conditions
- Lower Urinary Tract Symptoms, Stress Urinary Incontinence, Urge Urinary Incontinence, Overactive Bladder
- Trial name
- NCT07175805
- Testing
- Bariatric Surgery, GLP1 receptor agonist
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hartford HealthCare
Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
Registry of MIUS for Benign Prostatic Obstruction
This national, multicenter, prospective registry aims to collect standardized perioperative and follow-up data on patients undergoing minimally invasive surgical management for benign prostatic obstruction (BPO) in Turkey.
- Trial name
- ReMIUS-BPO (NCT07159165)
- Testing
- Minimally invasive surgical treatment for benign prostatic obstruction
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people
- Sponsor
- Ondokuz Mayıs University
Lower Urinary Track Symptoms, Multiple Sclerosis
Turkish Validity and Reliability of the Core Lower Urinary Tract Symptoms Questionnaire in Individuals With Multiple Sclerosis
The aim of this study is to study the validity and reliability of Core Lower Urinary Tract Symptoms Score in patients with multiple sclerosis.
- Trial name
- NCT06599866
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Kutahya Health Sciences University
Lower Urinary Tract Symptom, Benign Prostate Obstruction (BPO)
Uroflowmetry and IPSS Factors Influencing Surgical Decision
This study aims to identify which symptoms or test findings lead men with lower urinary tract symptoms (LUTS) to consider surgical treatment.
- Conditions
- Lower Urinary Tract Symptom, Benign Prostate Obstruction (BPO), Voiding Dysfunction
- Trial name
- NCT07047599
- Volunteers
- 100 people
- Sponsor
- Marmara University
Lower Urinary Tract Symptom, Voiding Dysfunction
Association Between Qmax/eGFR Ratio and LUTS Severity in Men Over 40
This study will look at how well a measure called the Qmax/eGFR ratio is related to the severity of urination problems in men over the age of 40.
- Conditions
- Lower Urinary Tract Symptom, Voiding Dysfunction, Male Urological Health, Renal Function
- Trial name
- NCT07055425
- Volunteers
- 100 people
- Sponsor
- Marmara University
Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia (BPH)
Uroflowmetry Curve Types and IPSS in Men With LUTS
This prospective observational study aims to evaluate the relationship between different uroflowmetry curve types and International Prostate Symptom Score (IPSS) domains in men presenting with lower urinary tract symptoms (LUTS).
- Conditions
- Lower Urinary Tract Symptoms (LUTS), Benign Prostatic Hyperplasia (BPH), Voiding Dysfunction
- Trial name
- UROFLOW-IPSS (NCT07016776)
- Volunteers
- 250 people
- Sponsor
- Tarik Emre Sener
Pelvic Floor Disorders, Lower Urinary Tract Symptoms
Respiratory and Pelvic Floor Muscle Functions of Children With Lower Urinary Tract Dysfunction
Lower urinary tract dysfunctions (LUTD) are disorders that can occur in the storage and voiding stages of bladder function other than neurological disease or lower urinary tract obstruction.
- Conditions
- Pelvic Floor Disorders, Lower Urinary Tract Symptoms, Physical Activity
- Trial name
- NCT06728540
- Testing
- Investigation of Physical Activity Levels, Respiratory and Pelvic Floor Muscle Function
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Seda Yakit Yesilyurt
Benign Prostatic Hyperplasia, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
A Phase III Clinical Study of H077 Sustained-Release Tablets Compared With Silodosin Capsules in the Treatment of Benign Prostatic Hyperplasia
This is a randomized, double-blind, controlled, non-inferiority multicenter Phase III clinical study to evaluate the efficacy and safety of H077 sustained-release tablets versus silodosin capsules in treating benign prostatic…
- Trial name
- NCT07146386
- Testing
- H077 sustained-release tablet, Silodosin capsules Control Group
- Where
- 66 sites in China
- Volunteers
- 728 people
- Sponsor
- Shanghai Huilun Pharmaceutical Co., Ltd.
Benign Prostatic Hyperplasia, Lower Urinary Tract Symptoms
Moses Vaporization: Is Use of Moses 2.0 in Holmium Laser Ablation of the Prostate More Efficient
To determine if use of Moses 2.0 results in improved ablation efficiency during holmium laser vaporization of the prostate. To determine if use of Moses 2.0 results in less char, improved visibility, and improved hemostasis in…
- Trial name
- Moses 2 (NCT04979143)
- Testing
- Surgical Approach
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Kansas Medical Center