Clinical trials: Urinary Tract Disease
Mood Disorders
Anergia-anhedonia by Lithium-induced Phosphorus Diabetes
Lithium (Li+) is prescribed to 1‰ of the French population (~ 60,000 patients). More than half of patients describe subjective symptoms linked to Li+ (SSL) similar to those of chronic fatigue syndrome: muscle weakness…
- Trial name
- ALIPo-D (NCT06111664)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Respiratory Tract Infections, Urinary Tract Infections
Intervention Study to Improve Antibiotic Prescription in Outpatient Care
Antimicrobial resistance has become a world-wide problem and antibiotic consumption is a major driving force for the development of resistance.
- Trial name
- SAPI (NCT01358916)
- Testing
- Mailing of antibiotic therapy guidelines to the sentinel physicians
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- University of Bern
Relapsed Pediatric Solid Tumors, Refractory Pediatric Solid Tumors
MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors
The purpose of this study is to determine if Magnetic Resonance guided High Intensity Focused Ultrasound ablative therapy is safe and feasible for children, adolescents, and young adults with refractory or relapsed solid tumors.
- Conditions
- Relapsed Pediatric Solid Tumors, Refractory Pediatric Solid Tumors, Rhabdomyosarcoma, Ewing Sarcoma
- Trial name
- NCT02076906
- Testing
- Magnetic Resonance High Intensity Focused Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- AeRang Kim
Renal Impairment, Hepatic Impairment
Hepatic Impairment and Renal Impairment Study of SIM0417 Combined With Ritonavir
This is a multicenter, nonrandomized, open-label, parallel controlled Phase I clinical study to evaluate the Pharmacokinetics, Safety and Tolerability of SIM0417 combined with ritonavir after a single dose in subjects with mild…
- Trial name
- NCT05731804
- Testing
- SIM0417 600 mg; Ritonavir100 mg, SIM0417 375 mg; Ritonavir100 mg, SIM0417 750 mg; Ritonavir100 mg
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Jiangsu Simcere Pharmaceutical Co., Ltd.
Overactive Bladder
OnabotulinumtoxinA (onaBoNT-A) Versus Oral Oxybutynin ER
Overactive bladder is a condition associated with symptoms of feeling the urge to urinate, urinating often, and may or may not be accompanied by leakage of urine.
- Trial name
- NCT01050114
- Testing
- onaBoNT-A, Oxybutynin ER
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Christopher Patrick Smith
Chronic Kidney Disease
Effect of Dietary Protein Source on Phosphaturia, PTH and FGF23 in Patients With CKD 3 and 4
Phosphorus is a substance in the blood that comes from food and is normally cleared from the body by the kidneys. In patients with kidney disease, excess phosphorus may build up in the body as you eat.
- Trial name
- NCT00764816
- Testing
- grain (soy) protein diet, casein (meat) protein diet
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Indiana University
Acute Kidney Injury (Nontraumatic), Contrast-induced Nephropathy
Maastricht Investigation of Renal Function in Absence of- and Post- Contrast in Patients With eGFR LEss Than 30
Intravascular iodinated contrast administration has become crucial to modern medicine. Currently it is estimated that over 250 million injections are given each year worldwide during medical scans and interventions.
- Conditions
- Acute Kidney Injury (Nontraumatic), Contrast-induced Nephropathy, Renal Insufficiency
- Trial name
- MIRACLE (NCT04598516)
- Testing
- serum creatinine assay
- Where
- Netherlands
- Sponsor
- Maastricht University Medical Center
Diabetic Nephropathy
A Study to Evaluate Pharmacodynamics, Safety, Tolerability and Pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects With Albuminuria and Moderately Decreased GFR
The purpose of this study is to evaluate pharmacodynamics, safety, tolerability and pharmacokinetics of MT-3995 in Type II Diabetic Nephropathy Subjects with Albuminuria and Moderately Decreased GFR
- Trial name
- NCT01756716
- Testing
- MT-3995 Low, MT-3995 High
- Where
- 50 sites in Bulgaria, Czechia and 4 more
- Volunteers
- 49 people
- Sponsor
- Tanabe Pharma Corporation
Renal Tumor
Cost-effectivness of Robot-assisted Surgery Compared to Open Surgery for Partial Nephrectomy in Context of Renal Tumor
This study aim to analyze cost-effectiveness of robot-assisted surgery compared to open surgery for partial nephrectomy in the context of renal tumor.
- Trial name
- écoREIN (NCT05089006)
- Testing
- Partial nephrectomy with robot-assisted and open surgery
- Volunteers
- 400 people
- Sponsor
- Central Hospital, Nancy, France
Cystic Fibrosis, Diabetes Mellitus Type I
Social Determinants in Chronic Disease in British Columbia
Anyone who practices clinical medicine will understand that socially disadvantaged children will have worse health outcomes, no matter what the underlying condition might be.
- Conditions
- Cystic Fibrosis, Diabetes Mellitus Type I, Chronic Renal Insufficiency
- Trial name
- NCT02203084
- Testing
- Social Determinants Questionnaire
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Type 2 Diabetes Mellitus, Chronic Kidney Disease
Evaluation of the Effect of Finerenone on Renal Function in Patients With Type 2 Diabetes and Chronic Kidney Disease
Research Objectives To evaluate the impact of finerenone on renal function, diabetic complications, and safety in patients with Type 2 diabetes and chronic kidney disease.
- Conditions
- Type 2 Diabetes Mellitus, Chronic Kidney Disease, Renal Function
- Trial name
- KSD-01 (NCT06838416)
- Testing
- Finerenone
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Hydronephrosis
Clinical Significance of Supranormal Differential Renal Function in the Recovery of Hydronephrosis
The purpose of this study is to assess the clinical significance of supranormal differential renal function (DRF) in the recovery of unilateral hydronephrosis (HN) after surgery, pediatric patients who underwent pyeloplasty for…
- Trial name
- NCT01839006
- Testing
- dismembered pyeloplasty
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Hospital
Kidney Disease, Chronic, Heart Failure
New Heart Failure Biomarkers in Early Stage Chronic Kidney Disease-Mineral and Bone Disorder
the objective of this study is to : -Determinate wether the circulating levels of iFGF23 and klotho can be a predictor biomarker of HF in patients with CKD-MBD.
- Trial name
- CKD-MBD-HF (NCT03307707)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Pr. Semir Nouira
Interstitial Cystitis
The Effects of Mindfulness-based Stress Reduction in Interstitial Cystitis Patients
This is a prospective cohort study to investigate differences in the bladder environment (i.e. urinary microbiome) amongst women with interstitial cystitis (IC) before and after undergoing mindfulness-based stress reduction…
- Trial name
- NCT03722992
- Testing
- MBSR
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- TriHealth Inc.
Purpura, Thrombocytopaenic, Idiopathic
Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal Impairment
The main purpose of this study is to compare how one 50 mg tablet of SB-497115 is broken down in the body by healthy subjects versus subjects with mild, moderate or severe kidney problems.
- Trial name
- NCT00442871
- Testing
- eltrombopag
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Underactive Bladder, TURP(transurethral Resection of Prostate)
The Efficacy of Pyridostigmine Therapy After Transurethral Resection of Prostate in Cases with Underactive Urinary Bladder.
The efficacy of pyridostigmine therapy after transurethral resection of prostate in cases with underactive urinary bladder
- Conditions
- Underactive Bladder, TURP(transurethral Resection of Prostate), BPH (Benign Prostatic Hyperplasia)
- Trial name
- NCT06753071
- Testing
- Pyridostigmine oral tablet
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Menoufia University
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Efficacy and Safety of MCS-2 in the Treatment of Lower Urinary Tract Symptoms
The hypothesis of the study is to examine whether MCS-2 is safe and effective in the treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia.
- Trial name
- MCS_LUTS (NCT01002664)
- Testing
- MCS-2
- Where
- Taiwan
- Volunteers
- 272 people
- Sponsor
- Health Ever Bio-Tech Co., Ltd.
Hematuria, Urothelial Carcinoma
STRATA: Safe Testing of Risk for AsymptomaTic MicrohematuriA
To evaluate the clinical utility associated with the integration of Cxbladder into the evaluation of subjects presenting with hematuria for evaluation of urothelial carcinoma (UC) without compromising detection of UC.
- Trial name
- NCT03988309
- Testing
- Cxbladder
- Where
- 12 sites in United States, Canada
- Volunteers
- 554 people
- Sponsor
- Pacific Edge Limited
Overactive Bladder
Post Marketing Survey of Vesicare in Japan
This study is to evaluate the effect of Vesicare on quality of life (QOL) in female patients.
- Trial name
- SET-Q (NCT01489709)
- Testing
- Vesicare
- Where
- 8 sites in Japan
- Volunteers
- 1,160 people
- Sponsor
- Astellas Pharma Inc
Urinary Tract Infection
Safety and Efficacy of PP4001 for the Treatment of Symptoms Associated With Uncomplicated Urinary Tract Infection
PP4001 is a medication not yet approved by the US FDA. This is a phase 2, multi-center, randomized, double-blind study of 3 doses of PP4001 versus placebo in the treatment of symptoms associated with uncomplicated urinary tract…
- Trial name
- NCT01406587
- Testing
- PP4001
- Where
- 25 sites in United States
- Volunteers
- 261 people
- Sponsor
- Pinnacle Pharmaceuticals, Inc.
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