Clinical trials: Urinary Tract Disease
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Capacity as Objective Measure of Intravesical Treatment of Newly Diagnosed IC
A comparative study of subjective outcomes following intravesical treatment of interstitial cystitis (IC) is lacking in the literature.
- Trial name
- NCT05223244
- Testing
- bupivacaine, triamcinolone, and heparin (BTH), dimethyl sulfoxide (DMSO)
- Volunteers
- 83 people
- Sponsor
- Endeavor Health
Cirrhosis, Hepatorenal Syndrome
Treatment of Hepatorenal Syndrome With Terlipressin Plus Albumin vs Albumin
Hepatorenal syndrome is a common complication of cirrhotic patients. The prognosis of patients with HRS is very poor. It have been demonstrated that vasoconstrictors agents (Terlipressin) plus albumin are effective in the…
- Trial name
- NCT00287664
- Testing
- terlipressin
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clinic of Barcelona
Urinary Tract Infection, Kidney Diseases
A Randomized Control Trial Comparing Single vs. Multiple Application of Lidocaine Analgesia Prior to Urethral Catheterization Procedures
The purpose of this study is to determine if a single application of Lidocaine gel topical anesthesia is as effective in decreasing the discomfort associated with urinary catheterization as two applications, within our pediatric…
- Conditions
- Urinary Tract Infection, Kidney Diseases, Ureteral Diseases, Ureteral Obstruction
- Trial name
- NCT00142064
- Testing
- observed levels of pain
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Bladder Cancer
Prospective Collection of Samples for Urothelial Cancer of Bladder
ProCSUCaB (Prospective Collection of Samples for Urothelial Cancer of Bladder) is a monocentric, non-interventional, prospective registry that will recruit newly diagnosed intermediate- and high-risk NMIBC patients in a tertiary…
- Trial name
- ProCSUCaB (NCT04167332)
- Volunteers
- 630 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetes Mellitus, Diabetic Nephropathy
Role of Triglyceride-Glucose Index and Inflammatory Biomarkers as Prognostic Tools for Progression of Diabetic Nephropathy
This study aims to evaluate the prognostic value of the Triglyceride-Glucose (TyG) index alongside inflammatory biomarkers in predicting the progression of diabetic nephropathy, exploring their correlation with disease severity…
- Trial name
- NCT07813793
- Volunteers
- 105 people
- Sponsor
- Assiut University
Bladder Cancer, Benign Prostate Hyperplasia
The Effect of Preemptive Analgesia On The Comfort Of Patient and Doctor, in Cystoscopy
The study was designed as a prospective, randomized double-blind placebo controlled trial. According to power analysis in regards of previous studies in the literature with diclofenac sodium, using a total of 144 patients are…
- Conditions
- Bladder Cancer, Benign Prostate Hyperplasia, Hematuria, Pain
- Trial name
- NCT03831321
- Testing
- Diclofenac Sodium, Cystoscopy, Lubricant Gel
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Taha Uçar
Autosomal Dominant Polycystic Kidney Disease
The Safety and Efficacy of Catheter-based Renal Denervation Using the Vessix™ Renal Denervation System in Autosomal Dominant Polycystic Kidney Disease (ADPKD) Patients With Severe Debilitating Pain
This study will test the safety and efficacy of the Vessix Renal Denervation system in the reduction of pain in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD).
- Trial name
- NCT02746419
- Testing
- Vessix
- Sponsor
- University of Chicago
Infective Endocarditis
Effect of Dexmedetomidine on Postoperative Renal Function in Infective Endocarditis Patients Undergoing Open Heart Surgery
Acute kidney injury is major complication after open heart surgery. The cause of acute kidney injury following open heart surgery is related to activation of sympathetic nervous system, decrease of renal blood flow…
- Trial name
- NCT02698930
- Testing
- dexmedetomidine, Normal saline
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Yonsei University
Survivorship, Prostate Cancer
An Acupuncture Study for Prostate Cancer Survivors With Urinary Issues
The purpose of this study is to test whether acupuncture can improve nocturia in prostate cancer survivors. This is the first time acupuncture is being studied for nocturia in prostate cancer survivors.
- Trial name
- NCT05540392
- Testing
- Acupuncture, Waitlist Control, Questionnaires
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Urinary Bladder Neoplasms
A Study of Stimulator of Interferon Genes (STING) Agonist E7766 in Non-muscle Invasive Bladder Cancer (NMIBC) Including Participants Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy, INPUT-102
This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intravesically in participants with NMIBC.
- Trial name
- NCT04109092
- Testing
- E7766
- Where
- 9 sites in United States
- Sponsor
- Eisai Inc.
Uterovaginal Prolapse, Urinary Incontinence
Use of Artificial Intelligence by Urogynecologic Patients
The goal of this clinical trial is to learn about how Urogynecology patients use Artificial Intelligence (AI) Chatbots like ChatGPT, and how it affects healthcare decision making.
- Conditions
- Uterovaginal Prolapse, Urinary Incontinence, Lower Urinary Tract Symptoms
- Trial name
- NCT06481436
- Testing
- Use of ChatGPT
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Hartford Hospital
Kidney; Disease (Functional), Chronic Kidney Disease
Early Screening and Diagnosis of CKD
Chronic kidney disease (CKD) is a global public health problem. The prevalence of CKD in adults in China was 10.8%. Albuminuria measurement and estimating glomerular filtration rate (GFR) are the primary means of screening for…
- Trial name
- NCT02841371
- Testing
- 99mTc-DTPA
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Advanced Cancer, Advanced Malignancies
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
- Conditions
- Advanced Cancer, Advanced Malignancies, Bladder Cancer, Cervical Cancer
- Trial name
- ARC-25 (NCT05891171)
- Testing
- AB598, Zimberelimab, Fluorouracil
- Where
- 19 sites in United States, Australia and 1 more
- Volunteers
- 40 people
- Sponsor
- Arcus Biosciences, Inc.
Gynecologic Cancer, Urinary Incontinence
Physiotherapy Treatment for Gynecological Cancer Survivors With Urinary Incontinence
The aims of this pilot study are to examine the feasibility and to explore the effects of a physiotherapy treatment compared to standard usual care in gynecological cancer survivors with urinary incontinence in preparation of a…
- Trial name
- NCT03957434
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Université de Sherbrooke
Acute Kidney Injury, Chronic Kidney Disease
Evaluating the Role of Cystatin C and Creatinine as Markers of Renal Recovery in Critically Ill Patients After Acute Kidney Injury.
This is a cohort study in which patients who survive Acute Kidney Injury (AKI) during intensive care unit (ICU) admission are recalled at 3-6 months and renal function tests are performed.
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Acute Kidney Disease
- Trial name
- NCT02894164
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 336 people
- Sponsor
- Karolinska Institutet
Diabetic Kidney Disease
The Multi-Center Clinical Study of Tang Shen Prescription on Type 2 Diabetic Kidney Disease in Early Stage
This study is a randomized, double-blinded, placebo-controlled clinical trial on type 2 diabetic Kidney Disease in early stage ( microalbuminuria excretion rate = 20-200mg/min) to evaluate the therapeutic effect of tang shen…
- Trial name
- NCT03009864
- Testing
- Tangshen Prescription
- Where
- China
- Volunteers
- 632 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Urinary Tract Infection
Single Dose Monurol for Treatment of Acute Cystitis
Urinary tract infecton (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20's.
- Trial name
- NCT00976963
- Testing
- TMP/SMX, Fosfomycin
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetic Kidney Disease, Diabetes Mellitus, Type 2
Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy
The study is focused on the possible improving effect of N-acetylcysteine on nephropathy of type-2 diabetic patients. Study design: Prospective clinical based study.
- Conditions
- Diabetic Kidney Disease, Diabetes Mellitus, Type 2, Diabetic Nephropathies
- Trial name
- (NAC) (NCT04531163)
- Testing
- N Acetylcysteine
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Erectile Dysfunction, Overactive Bladder
Mirabegron For Erectile Dysfunction
The only class of oral erectile dysfunction (ED) medication on the market are the phosphodiesterase Type 5 inhibitors (PDE5i). This pilot study is being done to evaluate the effect of Mirabegron, an oral beta-3 adrenergic…
- Conditions
- Erectile Dysfunction, Overactive Bladder, Urinary Incontinence
- Trial name
- NCT02916693
- Testing
- Mirabegron
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Hematuria, Urothelial Carcinoma
Urine DNA Methylation Detection for Hematuria Evaluation
Background: Hematuria, a common symptom of urinary system diseases, can result from various causes including infection, stones, trauma, and tumors.
- Conditions
- Hematuria, Urothelial Carcinoma, Bladder Cancer, Ureter Cancer
- Trial name
- NCT06427993
- Where
- China
- Volunteers
- 71 people
- Sponsor
- Changhai Hospital
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