Clinical trials: Urinary Tract Disease
Refractory Lupus Nephritis, Systemic Sclerosis
Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH.
This is a single-center, open-label, non-randomized, single-arm clinical trial. Patients with refractory lupus neritis (SLE-LN), systemic sclerosis (SSc), and primary Sjogren syndrome combined with pulmonary artery hypertension…
- Conditions
- Refractory Lupus Nephritis, Systemic Sclerosis, Primary Sjogren's Syndrome Combined With Pulmonary Hypertension
- Trial name
- NCT06947473
- Testing
- umbilical cord blood CD19-BCMA CAR-T cells infusion
- Where
- China
- Volunteers
- 45 people
- Sponsor
- Beijing GoBroad Hospital
Surgery, Knowledge, Attitudes, Practice
What is the Impact of the Presence of a Support Person on Informed Consent
In practice, the Investigators recommend that patients bring a family member or close friend to their pre-operative appointment to help with patient anxiety, comprehension, and informed decision-making.
- Conditions
- Surgery, Knowledge, Attitudes, Practice, Prolapse, Vaginal, Urinary Incontinence
- Trial name
- NCT03966469
- Testing
- Preoperative support person present, Patient Present Only
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Hartford Hospital
Kidney Stone, Surgery
Regional Erector Spinae Analgesic Block vs Standard of Care Undergoing Percutaneous Nephrolithotomy
The purpose of this study is to determine if adding a spinal block (medicine that will numb parts of the body to block pain) along with standard pain control at the incision site will decrease the need for narcotics for pain…
- Trial name
- NCT04663269
- Testing
- 4mg PF Dexamethasone, Control Test
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Indiana University
Urethral Stricture, Male
Small Intestinal Submucosa Graft for Repair of Anterior Urethral Strictures
The field of research for this study is tissue engineering and the utilization of a small intestinal submucosa graft as a substitute biomaterial for conventional buccal mucosa in substitution urethroplasty of anterior urethral…
- Trial name
- NCT06192654
- Testing
- Small intestinal submucosa (SIS) graft urethroplasty, Autologous oral bucal mucosa graft urethroplasty
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xiaoyong Zeng
Kidney Cancer, Melanoma (Skin)
Conformal Radiation Therapy in Treating Patients With Metastatic Cancer Outside the Brain
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Conditions
- Kidney Cancer, Melanoma (Skin), Metastatic Cancer, Ovarian Cancer
- Trial name
- NCT00550654
- Testing
- questionnaire administration, 3-dimensional conformal radiation therapy, hypofractionated radiation therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Asthma
Concentrations of Formoterol in Blood and Urine
The purpose of the study is to assess the blood and urine concentrations of inhaled formoterol.
- Trial name
- NCT00914654
- Testing
- inhaled formoterol
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
End-Stage Renal Disease
Pharmacokinetics Study of Donepezil HCl in Subjects Receiving Haemodialysis.
The purpose of this study is to investigate the pharmacokinetics of donepezil HCl 3 mg in subjects with end-state renal disease who were receiving haemodialysis.
- Trial name
- NCT01063556
- Testing
- donepezil HCl
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Eisai Co., Ltd.
Urinary Incontinence
Urinary Incontinence: Reproductive/Hormonal Risk Factors
This study is a continuation or follow-up of two previous studies (RRISK and RRISK2) conducted at the Kaiser Division of Research.
- Trial name
- RRISK3 (NCT00836979)
- Where
- United States
- Volunteers
- 2,161 people
- Sponsor
- Kaiser Permanente
Renal Cell Carcinoma
Dynamic Contrast Enhancement Computed Tomography for Evaluating Tumor Perfusion in Patients With Metastatic Renal Cell Carcinoma Receiving Targeted Therapies: Renal Cell Carcinoma (RCC) Scramble
This is a companion protocol to MD Anderson Cancer Center study 2010-0085 (Sequential Therapy in Advanced Renal Cell Carcinoma Therapy: The "START" Trial).
- Trial name
- NCT01224288
- Testing
- Perfusion CT scan
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- M.D. Anderson Cancer Center
Urinary Bladder, Overactive
A Clinical Study in Patients With Overactive Bladder With Leakage of Urine, to Find Out if the Medicine, Fesoterodine, Works in Those Patients Who Did Not Have Enough Response to the Medicine, Tolterodine.
Patients with overactive bladder are often treated with tolterodine, a medication that helps relax the bladder, helping symptoms of urinary incontinence and urinary frequency.
- Trial name
- NCT01302054
- Testing
- Fesoterodine 8 mg
- Where
- 176 sites in United States, Bulgaria and 13 more
- Volunteers
- 990 people
- Sponsor
- Pfizer
Urinary Infection
Position of Children During Urine Collection: Evaluation Study
Urinary tract infection (UTI) is a frequently suspected cause of fever in young children, justifying urine cultures. Sampling procedures are decisive for the reliability of UTI diagnosis.
- Trial name
- PUCES (NCT01862822)
- Testing
- upright position
- Where
- France
- Volunteers
- 803 people
- Sponsor
- University Hospital, Limoges
Proteinuria
Dextromethorphan and Silymarin in Chronic Kidney Disease (CKD) Patients
The investigators test the renal and cardiovascular protective effects dextromethorphan and silymarin on patients with the proteinuric chronic kidney diseases, who enrolled in our clinical trial, had progressing kidney diseases…
- Trial name
- CKD (NCT01091324)
- Testing
- Dextromethorphan, Silymarin, sugar pill
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- National Cheng-Kung University Hospital
Stress Urinary Incontinence
Solace European Confirmatory Trial
The Solace European Confirmatory (SOLECT) Trial is designed to determine whether the Solace Bladder Control System is safe and effective for the treatment of Stress Urinary Incontinence (SUI) in adult females.
- Trial name
- SOLECT (NCT01676662)
- Testing
- Solace Bladder Control System
- Where
- 7 sites in Belgium, Italy and 1 more
- Volunteers
- 80 people
- Sponsor
- Solace Therapeutics, Inc.
Renal Insufficiency, Chronic
Interleukin-1 Trap to Treat Vascular Dysfunction in Chronic Kidney Disease (CKD)
Risk of cardiovascular diseases (CVD) is significantly elevated in patients with chronic kidney disease (CKD); however, this increased risk is only partially explained by traditional cardiovascular risk factors.
- Trial name
- NCT01663103
- Testing
- Rilonacept
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of Colorado, Denver
Renal Artery Stenosis, Hypertension, Renovascular
Renal Stent Placement for the Treatment of Renal Artery Stenosis in Patients With Resistant Hypertension
The purpose of this trial is to test how well the iCAST™ RX Stent works in patients diagnosed with atherosclerotic renal artery stenosis and whether or not increased blood flow by the stent will help to control blood pressure.
- Trial name
- ARTISAN (NCT01673373)
- Testing
- iCAST™ Rx Stent System
- Where
- 12 sites in United States
- Volunteers
- 68 people
- Sponsor
- Atrium Medical Corporation
Gastric Cancer, Renal Cell Carcinoma
A Study of HFB200301 as a Single Agent and in Combination With Tislelizumab in Adult Patients With Advanced Solid Tumors
The purpose of this study is to test the safety and tolerability of HFB200301 as a single agent and in combination with tislelizumab in patients with advanced cancers. There are two parts in this study.
- Conditions
- Gastric Cancer, Renal Cell Carcinoma, Melanoma, Sarcoma
- Trial name
- NCT05238883
- Testing
- HFB200301, Tislelizumab
- Where
- 10 sites in United States, Spain
- Volunteers
- 72 people
- Sponsor
- HiFiBiO Therapeutics
Fertility
Bladder Exstrophy (FIVES FertIlity Vesical Exstrophy Sexuality)
This analytical descriptive study aims to describe the fertility and sexuality male adult subjects carrying classic bladder exstrophy or epispadias and to highlight infertility risk factors.
- Trial name
- FIVES (NCT02759705)
- Sponsor
- Hospices Civils de Lyon
Nutrition Disorders, Child
Nutritional Assessment of Children With Chronic Kidney Disease
Primary outcome is assessment of nutritional status of children with CKD. Secondary outcome is assessment STAMP screening tool for detection of malnutrition of CKD children.
- Trial name
- NCT04584905
- Testing
- dietary supplements for CKD patients
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bladder Cancer, Bladder Outflow Obstruction
Day-case Endourology; Patient Experience
A qualitative research study interviewing patients treated in hospitals across England. We will interview patients who have recently undergone one of the following operations as a day-case; transurethral bladder tumour resection…
- Trial name
- NCT06152679
- Testing
- None - qualitative interviews
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Primary Hyperoxaluria, Dent Disease
Rare Kidney Stone Consortium Biobank
This study is being done to obtain samples from patients with primary hyperoxaluria, cystinuria, adenine phosphoribosyl transferase (APRT) deficiency, and Dent disease, and from their family members, for use in future research.
- Conditions
- Primary Hyperoxaluria, Dent Disease, APRT Deficiency, Cystinuria
- Trial name
- NCT02026388
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Mayo Clinic
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