Clinical trials: Urinary Tract Infection(UTI)
Urinary Tract Infections, Bladder Cancer
Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB)
Antimicrobial prophylaxis in urological procedures is aimed to reduce the risk of local and systemic postoperative infections such as urinary tract infection or surgical site infection.
- Conditions
- Urinary Tract Infections, Bladder Cancer, Urologic Surgical Procedures
- Trial name
- NCT04209192
- Testing
- Fosfomycin Tromethamine 3G Sachet, Amikacin
- Where
- Mexico
- Volunteers
- 75 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Urinary Tract Infections, Urinary Tract Infections Caused by Drug-resistant Bacteria
Evaluation of Safety and Efficacy of Phage Therapy for Drug-resistant Bacterial Infections: An Exploratory, Prospective Single-arm Study
This study is an investigator-initiated, single-center, exploratory clinical trial designed to evaluate the safety and efficacy of phage therapy in patients with urinary tract infections caused by drug-resistant bacteria.
- Trial name
- Phage Therapy (NCT07382271)
- Testing
- Personalized Phage Cocktail
- Volunteers
- 6 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Urinary Tract Infections, Recurrent
Bovine Colostrum for Prophylaxis Against Recurrent Urinary Tract Infection in Children
Prebiotics as bovine colostrum are considered as a valuable supplement in the prevention of upper respiratory tract infections, gastrointestinal tract infections and neonatal sepsis.
- Conditions
- Urinary Tract Infections, Recurrent, Child, Prevention & Control
- Trial name
- NCT06164600
- Testing
- Bovine colostrum
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Multiple Sclerosis, Urinary Tract Infections
Cranberry for Prevention of Urinary Tract Infections in Multiple Sclerosis Patients
Bladder dysfunction occurs at some time in most patients with multiple sclerosis and these patients are prone to have recurrent urinary tract infections.
- Conditions
- Multiple Sclerosis, Urinary Tract Infections, Bladder Dysfunction
- Trial name
- CANNEBERGE (NCT00280592)
- Testing
- Cranberry
- Where
- 10 sites in France
- Volunteers
- 171 people
- Sponsor
- Rennes University Hospital
Urinary Tract Infections, Urinary Stone
Urine pH and Urinary Tract Infection
Urinary tract infections (UTI) affect the urine pH and may lead to salt precipitation such as struvite. Bacteria with urease activity are known to alkalinise urine, but not much is known on how pH is changing over time during…
- Trial name
- PHURINE (NCT04598971)
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Urinary Tract Infection, Spinal Cord Injury
Vitamin C for Prevention of Urinary Tract Infections in the Spinal Cord Injured
After spinal cord injury, patients have frequent urinary tract infections (UVI). Vitamin C is usually prescribed to prevent such infection, but the efficacy of the treatment is poorly documented.
- Trial name
- NCT00869427
- Testing
- vitamin C
- Volunteers
- 40 people
- Sponsor
- Sunnaas Rehabilitation Hospital
Recurrent Urinary Tract Infections
Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health…
- Trial name
- BIrUTI (NCT04846803)
- Testing
- ABU bladder lavage, Saline bladder lavage
- Where
- 2 sites in Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Fever, Respiratory Tract Infections
A Retrospective, Blinded Validation of a Host-response Based Diagnostics
This is a retrospective, blinded, external validation study of a novel in-vitro diagnostic (IVD) assay that will include samples that were previously collected from febrile pediatric patients.
- Conditions
- Fever, Respiratory Tract Infections, Urinary Tract Infections, Gastroenteritis
- Trial name
- PATHFINDER (NCT01911143)
- Where
- 2 sites in Israel
- Volunteers
- 600 people
- Sponsor
- MeMed Diagnostics Ltd.
Urinary Tract Infections
Urinary Tract Infection in Pregnancy
to describe the profile of uropathogenic E coli from Egyptian pregnant women with UTIs and a symptomatic bacteriuria. to determine the susceptibility pattern of our local isolated UPEC strains which is essential for optimal…
- Trial name
- NCT04244526
- Testing
- Talking a urine sample
- Volunteers
- 155 people
- Sponsor
- Assiut University
Urinary Tract Infections
Observational Study With Mode of Action-Analysis of Cystorenal Cranberry Extract in Patients With Recurrent Urinary Tract Infections
The main focus of this observational study is to analyze the possible effects of cranberry dietary supplements on the intestinal microbiota in women with recurrent uncomplicated urinary tract infections.
- Trial name
- NCT03019874
- Testing
- Cranberry Extract
- Where
- Germany
- Volunteers
- 23 people
- Sponsor
- Charite University, Berlin, Germany
Urinary Tract Infections, Sepsis
Use of Antibiotic Based Irrigation for Ureteroscopic Treatment of Urolithiasis
The purpose of the study is to investigate whether the use of gentamicin-based irrigation fluid during ureteroscopy decreases the risk of UTIs and other post-operative infections after surgery.
- Trial name
- NCT06007352
- Testing
- Gentamicin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Complicated Urinary Tract Infection, Pyelonephritis
MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)
This study aims to evaluate the safety and tolerability of MK-7625A (ceftolozane/tazobactam) compared with that of meropenem in pediatric participants with cUTI, including pyelonephritis.
- Trial name
- NCT03230838
- Testing
- Ceftolozane/Tazobactam, Meropenem
- Where
- 52 sites in United States, Greece and 8 more
- Volunteers
- 134 people
- Sponsor
- Merck Sharp & Dohme LLC
Urinary Tract Infections, Alternative Medicine
Efficacy of Unani Formulations (HBR and SBM) for Treating Uncomplicated UTIs
Based on a huge literature search a gap is found for a complete cure of Urinary Tract Infection (UTI) through the management of traditional antibiotic medicine.
- Conditions
- Urinary Tract Infections, Alternative Medicine, Women Health
- Trial name
- HBR-SBM (NCT06742918)
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Hamdard University
Urinary Retention, Urinary Tract Infection (Diagnosis)
How the Method of Bladder Emptying After Epidural Placement in Labor Affects Postpartum Voiding
At least ten percent of patients have postpartum urinary retention or difficulty urinating after birth, which can cause incontinence and other urinary problems long-term.
- Conditions
- Urinary Retention, Urinary Tract Infection (Diagnosis), Postpartum Acute Urinary Retention, Postpartum Care
- Trial name
- NCT07125326
- Testing
- Intermittent catheterization, Continuous catheterization
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Pittsburgh
Urinary Tract Infection, Fluoroquinolone
Clinical Impact of Fluoroquinolone Resistance in Bacteremia Caused by Gram-Negative Bacilli of Urinary Tract Origin
The information collected will optimize the management of patients with urinary tract infections with secondary bacteremia, primarily with gram negative bacteria especially Escherichia coli.
- Conditions
- Urinary Tract Infection, Fluoroquinolone, Bacteremia
- Trial name
- NCT00414362
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
Urinary Tract Infections, Communication
Communication and Compliance for Antibiotic Prescribing by General Practice to Nursing Home Residents With Suspected UTI
Antibiotic resistance is becoming a bigger problem. If the problem remains unsolved, the WHO predicts a return to the pre-antibiotic era.
- Conditions
- Urinary Tract Infections, Communication, Compliance, Medication
- Trial name
- NCT03700060
- Where
- Denmark
- Volunteers
- 459 people
- Sponsor
- Research Unit Of General Practice, Copenhagen
Stress Urinary Incontinence
Assessing the Utility of Prophylactic Antibiotics at Time of Urethral Bulking Using Bulkamid (Bulkamid Study)
The primary aim of this study is to assess the utility of prophylactic oral antibiotics at time of Bulkamid transurethral bulking to reduce the incidence of urinary tract infection (UTI) in the immediate postoperative period.
- Trial name
- NCT06706362
- Testing
- Bactrim or Macrobid
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Ohio State University
Urinary Tract Infections, Vaginal Flora Imbalance
Vaginal Care System for Menopausal Women With Urinary Tract Infections
Menopausal women have an increased risk of recurrent urinary tract infections. This is likely due in part to hormonal changes occurring during menopause.
- Trial name
- NCT05573334
- Testing
- BioNourish
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vaginal Biome Science
Recurrent Urinary Tract Infection
Probiotics for Girls With Recurring Urinary Tract Infections
Probiotics are dietary supplements containing potentially beneficial bacterial strains such as Lactobacillus. The safety of oral administration of probiotics has been demonstrated in hundreds of studies using adults over the last…
- Trial name
- NCT00789464
- Testing
- Lactobacillus reuteri DSM 17938, trimethoprim/sulfamethoxazole
- Where
- United States
- Sponsor
- Baylor College of Medicine
Urinary Tract Infection
Safety and Efficacy Study of Oral Fosfomycin Versus Oral Levofloxacin to Treat Complicated Urinary Syndromes (FOCUS)
This is a Phase 4, multi-center, open-label, randomized pragmatic superiority clinical trial comparing two strategies for initial or step-down oral therapy for complicated urinary tract infections (cUTI) after 0-48 hours of…
- Trial name
- NCT03697993
- Testing
- Fosfomycin tromethamine, Levofloxacin
- Where
- 12 sites in United States
- Volunteers
- 62 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)