Clinical trials: Urinary Tract Infection(UTI)
Spinal Cord Injury, Urinary Tract Infections
Adjuntive Probiotic Therapy in Treating Urinary Tract Infections in Spinal Cord Injury
We hypothesize that probiotic Lactobacillus can augment antibiotic treatment of symptomatic urinary tract infection (UTI) in spinal cord injured patients, and also increase the time to the next episode of UTI.
- Trial name
- NCT00594594
- Testing
- Probiotic Lactobacillus GR-1 and RC-14
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Gastroenteritis, Bronchiolitis
Isotonic Versus Hypotonic Fluid for Maintenance IV Therapy
Hyponatremia associated with administration of hypotonic intravenous (IV) fluids may have serious complications. It has recently been suggested that isotonic saline may be a more appropriate choice of maintenance IV fluid.
- Conditions
- Gastroenteritis, Bronchiolitis, Sepsis, Urinary Tract Infection
- Trial name
- NCT00457873
- Testing
- 0.9% saline in 5% dextrose (intravenous), 0.45% saline in 5% dextrose (intravenous)
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Urinary Incontinence, Urinary Tract Infections
Can the Use of Uricap Female Device Lead to Better Care for Women > 75+Years?
The purpose of the study is to evaluate if Uricap Female, an uridome for women, can be used instead of traditional incontinence aids to treat urinary incontinence (UI) among women 75 years and older.
- Conditions
- Urinary Incontinence, Urinary Tract Infections, Incontinence-associated Dermatitis, Cognition Disorders in Old Age
- Trial name
- U-PROTECT (NCT05275257)
- Testing
- Use of Uricap Female, a New Urine Collecting Device
- Where
- Sweden
- Sponsor
- Region Örebro County
Lower Urinary Tract Symptoms, Postoperative Urinary Tract Infection
Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy
This study will explore the application of placing heparin into the bladder via a catheter to decrease postoperative lower urinary tract symptoms (LUTS) and urinary tract infection (UTI) symptoms such as urinary frequency…
- Trial name
- HILUTS (NCT03633994)
- Testing
- Heparin, Normal saline
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- The Christ Hospital
Pressure Injuries, Pain
Adhesive Devices Versus Elastic Devices for Urinary Catheter Securement in Critically Ill Patients Experimental Study
Nowadays there are two types of urinary catheter securement devices, adhesive and elastic bands. The goal of this clinical trial is to determine which type of device-adhesive or elastic-is more effective for securing urinary…
- Conditions
- Pressure Injuries, Pain, Catheter-Associated Urinary Tract Infection, Medical Device Site Injury
- Trial name
- NCT07093437
- Testing
- GRIP-LOK FOLEY SECUREMENT DEVICE ®, CONVEEN, ELASTIC LEG WRISTBAND FOR URINARY CATHETER
- Where
- Spain
- Volunteers
- 188 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Recurrent Urinary Tract Infections
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement containing Lactiplantibacillus plantarum PBS067, Lacticaseibacillus rhamnosus LRH020, and Bifidobacterium animalis…
- Trial name
- BIO-RUTI-26 (NCT07884929)
- Testing
- Dietary Supplement containing probiotics
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Synbalance S.r.l.
Urinary Tract Infection
Efficacy and Safety of Nitrofurantoin in the Treatment of Uncomplicated Urinary Tract Infections in Adults
The study aims to investigate bacteriological efficacy of a nitrofurantoin formulation given twice daily for seven days in the treatment of adult patients with microbiologically confirmed uncomplicated urinary tract infection.
- Trial name
- NCT01092351
- Testing
- Nitrofurantoin
- Where
- Mexico
- Volunteers
- 37 people
- Sponsor
- Mepha Ltd.
Recurrent UTIs
Genitourinary Study of Fostering Lactobacillus to Optimize the Microbiome in Women's Health (GUD-FLORA)
The objective of this study is to evaluate the use of a vaginal probiotic in patients with recurrent urinary tract infections (UTIs).
- Trial name
- GUD-FLORA (NCT07234227)
- Testing
- Lactobacillus crispatus probiotic
- Sponsor
- Duke University
Urinary Tract Infections
Evaluating UTI Diagnosis in Nursing Homes
This prospective, multicenter, comparative cohort observational study is to determine whether the use of Guidance® UTI Clinical Pathway, a standardized infrastructure for specimen collection and result delivery, compared with…
- Trial name
- NCT04815369
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pathnostics
Urinary Tract Infections
Safety, Tolerability and Pharmacokinetic Investigation of GSK3882347 in Healthy Participants.
This is a phase 1, 2-part, double-blind (sponsor-unblinded), randomized, placebo-controlled, first time in human (FTIH) study, that includes both single-ascending and multiple-ascending dose phase to assess the safety…
- Trial name
- NCT04488770
- Testing
- GSK3882347
- Where
- United Kingdom
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy
Effect of Vulvar Re-Antisepsis Before CO₂ Cystoscopy Performed After Laparoscopic Hysterectomy on Postoperative Urinary Infections
This prospective observational study aims to evaluate whether additional vulvar re-antisepsis before intraoperative cystoscopy reduces the incidence of postoperative urinary tract infections (UTIs) in patients undergoing total…
- Conditions
- Postoperative Urinary Tract Infection, Laparoscopic Hysterectomy, Cystoscopy, Antisepsis
- Trial name
- NCT07232446
- Testing
- Additional Vulvar Re-Antisepsis Before Cystoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Alaattin Karabulut
Urinary Tract Infections
Evaluation of the Prevalence of E. Coli O Serotypes in Paediatric Population With Recurrent Urinary Tract Infection
This is a multicentre, observational, epidemiological study in which infants within the first 3 months of life with UTI and children aged ≥4 months with r-UTI will be recruited from nephrology /emergency departments and primary…
- Trial name
- rUTI (NCT06482151)
- Sponsor
- PENTA Foundation
Urinary Tract Infection(UTI)
E. Coli for Prevention of Catheter UTI in SCI Patients
The overall goal of this project is to develop a new approach for the prevention of urinary tract infection (UTI) in persons who rely on indwelling catheters for bladder drainage.
- Trial name
- NCT00458471
- Testing
- Insertion of a urinary catheter coated with benign E. coli
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Urinary Tract Infections
Cranberry Juice for the Prevention of Recurrent Urinary Tract Infections
This study will determine whether cranberry juice is effective in reducing recurrent urinary tract infections (UTIs) in women who have had a UTI within the past year.
- Trial name
- NCT00128128
- Testing
- Cranberry juice cocktail
- Where
- 2 sites in United States
- Volunteers
- 176 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Urinary Tract Infections
Effectiveness of Preurodynamic With Posturodynamic Levofloxacin on the Incidence of UTI
This study aims to compare the effectiveness of preoperative single dose of levofloxacin with postoperative levofloxacin for three days on the incidence of urinary tract infections (UTI) after urodynamic examination.
- Trial name
- NCT05219877
- Testing
- Pre-urodynamic Levofloxacin, Post-urodynamic Levofloxacin
- Where
- Indonesia
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Urinary Tract Infections
Clinical Efficacy of Crano-cure inTreatment of Urinary Tract Infection
The main objectives of the study are; to determine the efficacy of test drug Crano-cure for the treatment of urinary tract infection, to compare the effectiveness of Polyherbal formulation Crano-cure vs. Standard allopathic.
- Trial name
- NCT04575493
- Testing
- Crano-cure, Ciprofloxacin 500 mg
- Where
- 2 sites in Pakistan
- Volunteers
- 205 people
- Sponsor
- Islamia University of Bahawalpur
Bacteriuria, Spinal Cord Injuries
Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria
This is a Phase 1b study to assess the safety, tolerability, PK, and PD of investigational phage therapy (IP) in adults with SCI and bladder colonization (ASB).
- Conditions
- Bacteriuria, Spinal Cord Injuries, Asymptomatic Bacteriuria, Escherichia Coli
- Trial name
- Phage (NCT06559618)
- Testing
- Phage Therapy
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Barbara Trautner
Urinary Tract Infections
Urinary Tract Infection Due to Beta-lactamase-producing Enterobacteriaceae in Children
Urinary tract infection due to Extended-spectrum beta-lactamase producing enterobacteriaceae (E-ESBL UTI) become a frequent problem.
- Trial name
- PYELOBLSE (NCT02832258)
- Where
- 24 sites in France
- Volunteers
- 590 people
- Sponsor
- Fouad Madhi
Urinary Tract Infection (cUTI), Intra-abdominal Infection (cIAI) and
Reporting Patterns and Results of Initial Antibiotic Treatment in Patients With cUTI, cIAI,NP Including VAP
Reporting patterns and results of initial antibiotic treatment in patients with complicated urinary tract infection (cUTI), complicated intra-abdominal infection (cIAI) and nosocomial pneumonia (NP) including…
- Conditions
- Urinary Tract Infection (cUTI), Intra-abdominal Infection (cIAI) and, Nosocomial Pneumonia (NP)
- Trial name
- RECOMMEND (NCT02364284)
- Where
- 27 sites in Brazil, France and 4 more
- Volunteers
- 1,322 people
- Sponsor
- Pfizer
Ureteral Stones, Ureteral Calculi
Antibiotic Prophylaxis Before Shock Wave Lithotripsy
This is a two arm, double blind RCT comparing the use of a single dose ciprofloxacin prior to SWL to saline alone. The multicenter trial will be conducted with a pragmatic emphasis including both high volume and low volume sites…
- Conditions
- Ureteral Stones, Ureteral Calculi, Nephrolithiasis
- Trial name
- APPEAL (NCT03692715)
- Testing
- Ciprofloxacin
- Where
- 10 sites in Brazil, Canada and 7 more
- Volunteers
- 1,732 people
- Sponsor
- Clinical Urology and Epidemiology Working Group