Clinical trials: Urinary Tract Infection(UTI)
Urinary Tract Infection
A Study to Assess the Safety, Tolerability and Efficacy of Ertapenem Sodium in the Treatment of Complicated Urinary Tract Infections (0826-048)
The purpose of this study is to evaluate the safety, tolerability and efficacy of ertapenem sodium as initial therapy for the treatment of complicated urinary tract infections, including pyelonephritis in indian adults.
- Trial name
- NCT00379951
- Testing
- ertapenem sodium
- Volunteers
- 107 people
- Sponsor
- Merck Sharp & Dohme LLC
Recurrent Urinary Tract Infection in Adult Women
Evaluating the Effect of the Probiotic on Recurrent Urinary Tract Infection in Adult Women
Urinary tract infections (UTIs) are the most common bacterial infections in women, with about 50% of women experiencing at least one UTI in their lifetime.
- Trial name
- NCT03366077
- Testing
- Probiotic
- Where
- Sweden
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- BioGaia AB
Neonatal Urinary Tract Infection
Suprapubic Aspiration Versus Urinary Catheterization In Neonates.
Urinary tract infection (UTI) is relatively common in infants, with an occurence rate of up to 10%. Analysis of collected urine for the presence of bacteria or fungus is the only way to make a certain UTI diagnosis.
- Trial name
- SPA (NCT01726166)
- Testing
- Suprapubic Aspiration, Urinary Catheterization
- Where
- 2 sites in Canada
- Volunteers
- 49 people
- Sponsor
- Children's Hospital of Eastern Ontario
Urinary Tract Infections
Noroxin Efficacy and Safety Trial
To determine the efficacy and safety of Norfloxacin (Noroxin)
- Trial name
- NEST (NCT03506256)
- Testing
- Norfloxacin 400 MG
- Volunteers
- 1,000 people
- Sponsor
- OBS Pakistan
Urinary Tract Infections, Urinary Tract Infections in Children
Research of the Consequences on the Digestive Tract Following the Proposed Treatments for a Urinary Infection in Children
The emergence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (E-ESBL) is a major public health problem. It leads more frequent prescription of penems with the risk of emergence and spread of strains producing…
- Trial name
- MIKA (NCT03825874)
- Testing
- Amikacin, usual antibiotic treatment
- Where
- 20 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Urinary Tract Infection
Single Dose Monurol for Treatment of Acute Cystitis
Urinary tract infecton (UTI) is a very common problem in young healthy women, afflicting approximately one-half of women by their late 20's.
- Trial name
- NCT00976963
- Testing
- TMP/SMX, Fosfomycin
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Washington
Catherization, Urinary Tract Infection Bacterial
Betadine vs Sterile Water for Periurethral Preparation
The purpose of this study is to determine whether cleaning of the urethra, or external opening to the bladder, with sterile water (water that has been treated to remove bacteria and living organisms) vs Betadine also known as…
- Trial name
- NCT07044726
- Testing
- Povidone-Iodine, Sterile water
- Where
- 2 sites in United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Urinary Tract Infections
The Association of Gut Microbiota With Urinary Tract Infection in Infants
This prospective case-control study will compare the gut microbiota between the infants with febrile urinary tract infection and healthy infants.
- Trial name
- NCT04615689
- Testing
- The collection of feces
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Gram Negative Infections
A Study to Assess How Vaborem® is Taking up in the Body and Tolerated in Paediatric Patients With Gram Negative Infections, Including But Not Restricted to Complicated Urinary Tract Infections
The goal of this clinical trial is to assess the pharmacokinetic (PK) and safety and tolerability of Vaborem (fixed combination of meropenem and vaborbactam) in the paediatric population aged from birth to < 18 years with…
- Trial name
- NCT06828848
- Testing
- Meropenem plus vaborbactam
- Where
- 22 sites in Czechia, France and 3 more
- Volunteers
- 44 people
- Sponsor
- Menarini Group
Uncomplicated Urinary Tract Infections
Safety and Efficacy of Phenazopyridine Hydrochloride Tablets, USP 200 mg as an Analgesic for Short-Term Treatment in Female Subjects Suffering From Moderate-to-Severe Pain and Burning Upon Urination Associated With Uncomplicated Urinary Tract Infections (uUTI)
The primary objective is to evaluate the safety and efficacy of Phenazopyridine HCl Tablets, USP 200 mg as a short term analgesic treatment of pain upon urination associated with Uncomplicated Urinary Tract Infections (uUTI).
- Trial name
- NCT01650051
- Testing
- Phenazopyridine Hydrochloride Tables, USP 200 mg
- Where
- United States
- Volunteers
- 424 people
- Sponsor
- Amneal Pharmaceuticals, LLC
Recurrent Urinary Tract Infections in Women
Efficacy and Safety of Fecal Microbiota Transfer (FMT) for Recurrent Urinary Tract Infections in Women
Urinary tract infections (UTIs) are highly prevalent worldwide, especially in women, with frequent recurrences and significant healthcare costs.
- Trial name
- NCT07194941
- Testing
- Freeze-dried product made of fresh feces
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Urinary Tract Infections, Recurrent
Electroacupuncture for the Prevention of Recurrent Lower Urinary Tract Infection in Women
The goal of this clinical trial is to evaluate if electroacupuncture works to prevent recurrent lower urinary tract infections in female patients. It will also learn about the safety of electroacupuncture.
- Conditions
- Urinary Tract Infections, Recurrent, Electroacupuncture, Randomized Controlled Trial (RCT)
- Trial name
- rLUTI (NCT07507851)
- Testing
- Electroacupuncture
- Where
- 2 sites in China
- Volunteers
- 312 people
- Sponsor
- Yanjun Zhang, Baoyan Liu
Urinary Infection, Digestive Infection
Deescalating Carbapenems in Hospital Setting
The study aims to evaluate a deescalating therapeutic strategy (switch the carbapenem to another beta-lactam for which the isolated pathogen is susceptible) in patients with well-defined ESBL-PE infections (usual sites of…
- Conditions
- Urinary Infection, Digestive Infection, Biliary Infection, Expanded-spectrum Beta-lactamase Producing ESBL
- Trial name
- CARBEPARGNE (NCT02265445)
- Testing
- Deescalation therapy, Maintaining carbapenem therapy
- Volunteers
- 6 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Urinary Tract Infections, Recurrent Urinary Tract Infection
Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention
Antimicrobial prophylactic treatment of recurrent UTI is limited by emerging resistance, antibiotic allergies and intolerances. Intravesical aminoglycoside instillations (IAI) have been shown to reduce recurrence rate, without a…
- Trial name
- INSTILMENT (NCT05376670)
- Testing
- Intravesical aminoglycoside instillations
- Where
- Netherlands
- Volunteers
- 44 people
- Sponsor
- Leiden University Medical Center
Urinary Tract Infection, Antibiotic
The Impact of Irrisept in Reducing Urinary Tract Infection During Urethral Catheter Removal.
Given the high burden of post-catheter removal UTIs, this study aims to evaluate Irrisept instillation as a non-antibiotic intervention to reduce infection rates.
- Conditions
- Urinary Tract Infection, Antibiotic, Catheter Infection
- Trial name
- NCT07239219
- Testing
- 0.05% Chlorhexidine Gluconate, Normal Saline
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Health Care Associated Infection, Catheter-associated Urinary Tract Infection
Clinical Decision Support to Reduce Catheter Associated Urinary Tract Infections
The goal of this randomized controlled trial is to compare the effects of a clinical decision support tool consisting of a 48-hour stop order for indwelling urinary catheters versus no clinical decision support in hospitalized…
- Trial name
- NCT06454500
- Testing
- Clinical decision support
- Where
- 8 sites in United States
- Volunteers
- 79,369 people, healthy volunteers welcome
- Sponsor
- Columbia University
Urinary Catheterization, Thoracic Surgery
REduction of Post-Operative Urinary Retention With Tamsulosin Versus Placebo (REPOURT- P) Trial
The purpose of this study are to determine the efficacy of tamsulosin compared to placebo in reducing post-operative urinary retention and improving other clinical outcomes in people undergoing thoracic surgery.
- Conditions
- Urinary Catheterization, Thoracic Surgery, Thoracic Epidural Analgesia
- Trial name
- REPOURT-P (NCT04159077)
- Testing
- Tamsulosin Hydrochloride
- Volunteers
- 350 people
- Sponsor
- McMaster University
Kidney Calculi, Nephrolithiasis
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL).
- Conditions
- Kidney Calculi, Nephrolithiasis, Urinary Tract Infections
- Trial name
- DIOX-PCNL (NCT07393711)
- Testing
- Dioxidine, Percutaneous Nephrolithotripsy (PCNL)
- Where
- Kazakhstan
- Volunteers
- 95 people
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Urinary Tract Infection, Respiratory Tract Infection
Prolonged Infusion Cefepime and Nosocomial Infections
It is advocated that prolonged infusion of beta-lactamic antibiotics provides better bactericidal effect. The aim of the present study is to randomize patients a to extended cefepime infusion regimen (lasting four hours) or to a…
- Trial name
- PICNIC (NCT02568800)
- Testing
- Prolonged Cefepime Infusion, Usual Cefepime Infusion
- Where
- Brazil
- Volunteers
- 134 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Urinary Tract Infection (Diagnosis)
'Improving Urinary Tract Infection Diagnosis in Older Patients: Validation of a Biomarker Panel (UTI-GOLD)'
The goal of this study is to improve the diagnosis of urinary tract infections (UTI) in older people (≥65 years). The main research questions are: Research questions What is the optimal cut-off for each individual biomarker…
- Trial name
- UTI-GOLD (NCT06610721)
- Testing
- Urine Biomarkers
- Where
- Netherlands
- Volunteers
- 264 people
- Sponsor
- Leiden University Medical Center