Clinical trials: Urinary Tract Infection(UTI)
Recurrent Urinary Tract Infection
The Effect of Increased Water Intake on the Frequency of the Clinical Recurrent Urinary Tract Infections in Pre-menopausal Women: S-HYDRACYST
The purpose of this study is to determine whether increased water intake is effective in preventing episodes of uncomplicated urinary tract infections (UTI) in pre-menopausal women suffering from UTI recurrences.
- Trial name
- S-HYDRACYST (NCT02444975)
- Testing
- Mineral water, Coaching program, No intervention
- Where
- Bulgaria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Urinary Incontinence, Urinary Tract Infections
Can the Use of Uricap Female Device Lead to Better Care for Women > 75+Years?
The purpose of the study is to evaluate if Uricap Female, an uridome for women, can be used instead of traditional incontinence aids to treat urinary incontinence (UI) among women 75 years and older.
- Conditions
- Urinary Incontinence, Urinary Tract Infections, Incontinence-associated Dermatitis, Cognition Disorders in Old Age
- Trial name
- U-PROTECT (NCT05275257)
- Testing
- Use of Uricap Female, a New Urine Collecting Device
- Where
- Sweden
- Sponsor
- Region Örebro County
Urinary Tract Infections (UTIs), Urinary Tract Infection, Recurrent
Effects of Pomegranate Seed Oil Supplementation in Patients With Advanced Dementia
The goal of this clinical study is to learn if Pomegranate Seed Oil supplementation works to combat urinary tract infections, recurrenturinary tract infections, or pneumonia and contributes to the tapering or discontinuation of…
- Conditions
- Urinary Tract Infections (UTIs), Urinary Tract Infection, Recurrent, Antipsychotics Discontinuation, Antipsychotics Tapering
- Trial name
- NCT07432763
- Testing
- Pomegranate Seed Oil Supplementation in Palliative Care Patients with Advanced Dementia, Care-as-usual
- Where
- Greece
- Volunteers
- 18 people
- Sponsor
- Panhellenic Federation of Alzheimer's Disease and Related Disorders
Pressure Ulcer, Urinary Tract Infection
SAFE or SORRY? Patient Safety Study of the Prevention of Adverse Patient Outcomes
The aim of SAFE or SORRY? is to develop and test an evidence based inpatient safety program for the prevention of three frequently occuring adverse events: pressure ulcers, urinary tract infections and falls.
- Conditions
- Pressure Ulcer, Urinary Tract Infection, Accidental Falls
- Trial name
- NCT00365430
- Testing
- safety program
- Where
- 10 sites in Netherlands
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Urinary Tract Infection
A Study to Assess the Ability of 2% Lidocaine Gel to Reduce the Discomfort of Urethral Catheterization
Children 0-24 months of age requiring a urethral catheterization for urine collection will be randomized to receive either topical and intraurethral 2% lidocaine or standard of care to assess for the effectiveness of the former…
- Trial name
- NCT01690767
- Testing
- 2% lidocaine gel, Health Care Lubricating Jelly
- Where
- Canada
- Volunteers
- 133 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Urinary Tract Infection
Evaluation of Surface Acoustics Ultrasound Device for the Treatment of Patients With Percutaneous Nephrostomy Catheters
Catheter associated urinary tract infection is one of the most common types of catheter acquired infections and adds greatly to patient morbidity, mortality and medical cost.
- Trial name
- NV-US-04-001 (NCT00702286)
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Assaf-Harofeh Medical Center
Urinary Tract Infection Bacterial
Evaluation of the Efficacy and Safety of MV140
The purpose of the study is to evaluate the efficacy and safety of a biological vaccine (MV140) in women with Recurrent Urinary Tract Infections (RUTI) compared with a placebo group.
- Trial name
- MV140 (NCT02543827)
- Testing
- MV140
- Where
- 5 sites in Spain, United Kingdom
- Volunteers
- 240 people
- Sponsor
- Inmunotek S.L.
Recurrent Urinary Tract Infections, Antibiotic Prophylaxis
D Mannose for Prevention and Treatment of RUTIs
The aim of this review is to address clinical reliability, efficacy and safety of long-term treatment with oral D Mannose for the prevention of recurrent urinary tract infections (RUTIs) in females.
- Conditions
- Recurrent Urinary Tract Infections, Antibiotic Prophylaxis, Antibiotic Resistance
- Trial name
- mannoseRUTIs (NCT03790254)
- Testing
- systematic review
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Catheter-Associated Urinary Tract Infection
Smart Catheter: A Novel Biosensor for Early Detection of Catheter Associated Urinary Tract Infection
Urinary Tract Infection (UTI) is the most common hospital acquired infection worldwide, and is most commonly associated with catheterisation of the bladder.
- Trial name
- NCT04315129
- Testing
- Smart Catheter Biosensor
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Imperial College London
Prostatic Hyperplasia, Pyuria
Impact of Postoperative Pyuria on Treatment Outcomes After PVP
The aim of this study was to identify serial changes in the incidence of postoperative pyuria after the Photoselective Vaporization of the Prostate (PVP), to determine whether the presence of postoperative pyuria could be…
- Trial name
- NCT02241902
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- DongGuk University
Gram-negative Bacterial Infections, Hospital Acquired Bacterial Pneumonia (HABP)
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants
The primary objectives of this study are to assess the safety, tolerability, and pharmacokinetics (PK) of cefiderocol after single-dose administration in hospitalized pediatric participants 3 months to < 12 years of age with…
- Conditions
- Gram-negative Bacterial Infections, Hospital Acquired Bacterial Pneumonia (HABP), Complicated Urinary Tract Infection (cUTI), Ventilator Associated Bacterial Pneumonia (VABP)
- Trial name
- NCT04215991
- Testing
- Cefiderocol, Standard of Care
- Where
- 25 sites in United States, Australia and 8 more
- Volunteers
- 91 people
- Sponsor
- Shionogi
Urinary Tract Infections, Urinary Tract Infections in Children
Research of the Consequences on the Digestive Tract Following the Proposed Treatments for a Urinary Infection in Children
The emergence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (E-ESBL) is a major public health problem. It leads more frequent prescription of penems with the risk of emergence and spread of strains producing…
- Trial name
- MIKA (NCT03825874)
- Testing
- Amikacin, usual antibiotic treatment
- Where
- 20 sites in France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Complicated Urinary Tract Infection, Acute Pyelonephritis
A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP)
This was a randomized, multicenter, multinational, double-blind study comparing the efficacy and safety of plazomicin compared with meropenem followed by optional oral (PO) therapy in the treatment of cUTI, including AP, in…
- Trial name
- EPIC (NCT02486627)
- Testing
- plazomicin, meropenem, levofloxacin (oral)
- Volunteers
- 609 people
- Sponsor
- Achaogen, Inc.
Urinary Tract Infections, Recurrent Urinary Tract Infections
WMT for Multidrug-Resistant Organism UTI
This is a single-center, prospective, single-arm, exploratory clinical study to evaluate the efficacy, safety, and potential mechanisms of washed microbiota transplantation (WMT) in patients with recurrent urinary tract…
- Conditions
- Urinary Tract Infections, Recurrent Urinary Tract Infections, Multidrug-Resistant Bacterial Infections, Bacteriuria
- Trial name
- NCT07816913
- Testing
- Washed Microbiota Transplantation (WMT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Ureteral Stones
Is Prophylactic Antibiotics Necessary In Otherwise Healthy Adult Patients Undergoing Ureteroscopic Procedures for Ureteral Stones?
The present study aims to investigate the relative efficacy, safety and risk of a single-dose prophylaxis in otherwise healthy adult patients undergoing ureteroscopic procedures for ureteral stones.
- Trial name
- NCT02635490
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Pseudomonas Infections, Pseudomonas Septicemia
Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis
The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in…
- Conditions
- Pseudomonas Infections, Pseudomonas Septicemia, Pseudomonas; Pneumonia, Pseudomonal Bacteraemia
- Trial name
- MIPSA (NCT03044223)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Ulm
Uncomplicated Urinary Tract Infection
Supporting the Improvement and Management of Prescribing for Urinary Tract Infections (SIMPle)
Background The over use of antimicrobials is recognised as the main selective pressure driving the emergence and spread of antimicrobial resistance in human bacterial pathogens.
- Trial name
- SIMPle (NCT01913860)
- Testing
- Improving GP antibiotics prescribing behaviour
- Where
- Ireland
- Volunteers
- 2,577 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Urinary Tract Infection, Vesicoureteral Reflux
Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy
The study will be evaluating the efficacy and safety of a contrast drug in pediatric renal ultrasound.
- Trial name
- NCT02786810
- Testing
- Sulfur hexafluoride type-a lipid microspheres
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Patients With Complicated Urinary Tract Infection(cUTI), Including Acute Pyelonephritis(AP)
A Trial of Intravenous HRS-8427 in the Treatment of Adults With Complicate Urinary Tract Infection, Including Acute Pyelonephritis
The Purpose of this study is to evaluate the efficacy and safety of intravenous HRS -8427 in patients with complicated urinary tract infection, including acute pyelonephritis.
- Trial name
- NCT06144060
- Testing
- HRS -8427, Imipenem and Cilastatin Sodium
- Volunteers
- 126 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Recurrent Urinary Tract Infection
GAG Replacement vs URethral DIlAtatioN
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women.
- Trial name
- GUARDIAN (NCT03861260)
- Testing
- Rigid cystoscopy with urethral dilatation, Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
- Where
- United Kingdom
- Sponsor
- Hampshire Hospitals NHS Foundation Trust