Clinical trials: Urinary Tract Infection, Recurrent
Type 2 Diabetes Mellitus (T2DM), Recurrent Urinary Tract Infections
Cranberry Proanthocyanidins and Lactobacilli for Recurrent UTI Prevention in Type 2 Diabetes
The purpose of this prospective, single-arm feasibility study was to evaluate the operational feasibility, tolerability, safety, and exploratory clinical outcomes of an oral supplement combining standardized cranberry…
- Trial name
- NCT07832409
- Testing
- Cranberry Proanthocyanidins and Lactobacilli
- Where
- Georgia
- Volunteers
- 100 people
- Sponsor
- National Institute of Endocrinology, Georgia
Recurrent Urinary Tract Infection
GAG Replacement vs URethral DIlAtatioN
The aim of this randomised parallel trial is to compare the efficacy of Glycosaminoglycan layer replacement against cystoscopy and urethral dilatation in the treatment of recurrent urinary tract infection in pre-menopausal women.
- Trial name
- GUARDIAN (NCT03861260)
- Testing
- Rigid cystoscopy with urethral dilatation, Flexible cystoscopy and installation of Glycosaminoglycan layer replacement (laluril)
- Where
- United Kingdom
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Cancer
Thalidomide and Docetaxel in Treating Patients With Advanced Cancer
RATIONALE: Thalidomide may stop the growth of cancer by stopping blood flow to the tumor. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die.
- Trial name
- NCT00049296
- Testing
- docetaxel, thalidomide
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Case Comprehensive Cancer Center
Hematuria, Urination Disorders
Rigid Versus Flexible Cystoscopy in Women
The study will help define the best tolerated approach to cystoscopy in women by randomly comparing flexible to rigid cystoscopy.
- Conditions
- Hematuria, Urination Disorders, Voiding Dysfunction, Recurrent Urinary Tract Infection
- Trial name
- NCT00214045
- Testing
- Flexible Cystoscopy, Rigid Cystoscopy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Kidney Calculi, Nephrolithiasis
Metaphylaxis of Infected Kidney Stones After Percutaneous Nephrolithotripsy
Kidney stone recurrence, particularly infection-related stones, remains a significant clinical problem after percutaneous nephrolithotripsy (PCNL).
- Conditions
- Kidney Calculi, Nephrolithiasis, Urinary Tract Infections
- Trial name
- DIOX-PCNL (NCT07393711)
- Testing
- Dioxidine, Percutaneous Nephrolithotripsy (PCNL)
- Where
- Kazakhstan
- Volunteers
- 95 people
- Sponsor
- West Kazakhstan Marat Ospanov Medical University
Recurrent Urinary Tract Infection
Treatment of Recurrent Urinary Tract Infection (RUTI) by Traditional Chinese Medicine
Traditional Chinese Medicine (TCM) could be used to treat Recurrent urinary tract infection (RUTI).
- Trial name
- NCT01745328
- Testing
- LVX-AMX, TCM
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Beijing Institute of Disease Control and Prevention
Urinary Tract Infection
E. Coli 83972 Induced Asymptomatic Bacteriuria (ABU) in Patients With Recurrent Urinary Tract Infections (UTI)
This study tests the following hypothesis: Does induced asymptomatic bacteriuria (E. coli 83972) protect against symptomatic urinary tract infections in individuals with bladder emptying dysfunctions and prone to recurrent…
- Trial name
- NCT00927316
- Testing
- E. coli 83972
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Skane
Recurrent Urinary Tract Infection
Gag Therapy for Recurrent Urinary Tract Infection Assessing Comparability to International Nitrofurantoin Gold Standard Study
The GT RACING is a study comparing the efficacy of HA-CS bladder installations with prophylactic antibiotics in the prevention of recurrent urinary tract infections (rUTI).
- Trial name
- GT RACING (NCT05652374)
- Testing
- Ialuril 50ml Prefill, Nitrofurantoin
- Where
- 3 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Urinary Tract Infection Lower Acute
Clinical Study of Sanjin Tablets for the Treatment of Acute Simple Lower Urinary Tract Infection
The purpose of this study is to evaluate the efficacy, safety and immune mechanism of Sanjin tablets for the treatment of acute simple lower urinary tract infection and its influence on recurrence rate.
- Trial name
- NCT03658291
- Testing
- Sanjin tablets, Sanjin tablets simulants, Levofloxacin
- Volunteers
- 252 people
- Sponsor
- China Academy of Chinese Medical Sciences
Recurrent Urinary Tract Infection
Preference of Women With Recurrent Urinary Tract Infection for Vaginal Estradiol Tablet vs Cream
Vaginally applied estrogen has been shown to decrease the incidence of Recurrent Urinary Tract Infection (rUTI) in post-menopausal women. However, prior studies have shown the compliance rate for topical estrogen cream is low.
- Trial name
- NCT05723601
- Testing
- Estradiol vaginal cream, Estradiol Vaginal Tablet
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wake Forest University Health Sciences
Urinary Tract Infections (UTIs)
Evaluation of the Effectiveness and Safety of a Vaginal Gel for Prevention of Recurrent Urinary Tract Infections
Urinary Tract Infections (UTIs) are among the most common bacterial infections. Although they are typically treated effectively with antibiotics, recurrence is a frequent and troublesome issue.
- Trial name
- UTI (NCT07233473)
- Testing
- Multi-Gyn UT Protect gel
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Karo Pharma AB
Urinary Incontinence, Overactive Bladder
Pain-perception During Outpatient cystoscopy-a Prospective Controlled Study
At an academic tertiary referral center, patients with pelvic floor dysfunction, scheduled for outpatient cystoscopy or urodynamic testing will be asked to participate in the study.
- Conditions
- Urinary Incontinence, Overactive Bladder, Pelvic Organ Prolapse, Recurrent Urinary Tract Infections
- Trial name
- NCT01663181
- Where
- Austria
- Volunteers
- 109 people
- Sponsor
- Medical University of Vienna
Urinary Tract Infection
Intravaginal LACTIN-V for Prevention of Recurrent Urinary Tract Infection
Recurrent urinary tract infections (RUTIS) continue to be a major health problem in women and are now complicated by increasing antibiotic resistance. New preventive approaches are needed.
- Trial name
- NCT00305227
- Testing
- Lactin-V
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Washington
Recurrent UTIs, Recurrent Urinary Tract Infections
A Trial of D-mannose for the Prophylaxis of Recurrent Urinary Tract Infections
A randomized, double-blind, placebo-controlled, 12-month study to determine the effectiveness of D-mannose (2g daily) supplementation in rUTI (recurrent urinary tract infection) prevention in post-menopausal women.
- Conditions
- Recurrent UTIs, Recurrent Urinary Tract Infections, Recurrent Urinary Tract Infections in Women, Recurrent Urinary Tract Infection
- Trial name
- DmannoseRCT (NCT06940622)
- Testing
- D-Mannose
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Texas Southwestern Medical Center
Recurrent Urinary Tract Infection
Study to Evaluate the Efficacy of Lactobacillus Crispatus M247 in the Prevention of Recurrent Urinary Tract Infections
This randomized, open-label, controlled clinical trial evaluates the efficacy and safety of Lactobacillus crispatus M247 (CRISPACT®) in preventing recurrent urinary tract infections (rUTIs) in women.
- Trial name
- NCT06857565
- Testing
- Lactobacillus crispatus M247, iNatal-Duo® (containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3)
- Where
- Italy
- Volunteers
- 84 people
- Sponsor
- Liaquat University of Medical & Health Sciences
Urinary Tract Infections
MV-140 Efficacy in Recurrent Urinary Tract Infections in a Cohort of Portuguese Adult Patients
We will access the efficacy of MV-140 immunotherapy in the prevention of recurrent urinary tract infections in a cohort of Portuguese patients.
- Trial name
- NCT06392282
- Testing
- MV-140
- Where
- Portugal
- Volunteers
- 104 people
- Sponsor
- Unidade Local de Saúde Santa Maria
Urinary Tract Infection Bacterial
Evaluation of the Efficacy and Safety of MV140
The purpose of the study is to evaluate the efficacy and safety of a biological vaccine (MV140) in women with Recurrent Urinary Tract Infections (RUTI) compared with a placebo group.
- Trial name
- MV140 (NCT02543827)
- Testing
- MV140
- Where
- 5 sites in Spain, United Kingdom
- Volunteers
- 240 people
- Sponsor
- Inmunotek S.L.
Urinary Tract Infections, Recurrent Urinary Tract Infections
WMT for Multidrug-Resistant Organism UTI
This is a single-center, prospective, single-arm, exploratory clinical study to evaluate the efficacy, safety, and potential mechanisms of washed microbiota transplantation (WMT) in patients with recurrent urinary tract…
- Conditions
- Urinary Tract Infections, Recurrent Urinary Tract Infections, Multidrug-Resistant Bacterial Infections, Bacteriuria
- Trial name
- NCT07816913
- Testing
- Washed Microbiota Transplantation (WMT)
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Urinary Tract Infections
Uqora Supplements in Women With UTIs
This is a virtual study which will invite females over the age of 18 who have had 2 or more UTIs in the past 6 months to participate.
- Trial name
- NCT04024046
- Testing
- Uqora, Group1, Group 2
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Hawthorne Effect Inc.