Clinical trials: Urinary Tract Infection (UTI)
Urinary Tract Infection, Pelvic Organ Prolapse
L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract to Prevent Postoperative Urinary Tract Infection.
This study will include women who will undergo pelvic reconstructive surgery and/or anti-incontinence sling procedures. Patients will be randomized to the combination of L-methionine, Hibiscus Sabdariffa and Boswellia Leaf…
- Conditions
- Urinary Tract Infection, Pelvic Organ Prolapse, Urinary Incontinence
- Trial name
- NCT02216253
- Testing
- L-methionine, Hibiscus Sabdariffa and Boswellia Leaf Extract
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- IRCCS San Raffaele
Urinary Tract Infections
Identification of Predictive Blood Biomarkers of Recurrent Urinary Tract Infections
Urinary tract infections affect more than 130 million people worldwide each year. Almost 50% of women will have at least one urinary tract infection during their lifetime, usually cystitis.
- Trial name
- Predict-UTI (NCT03819712)
- Testing
- Collection of blood samples, Collection of fecal samples, Collection of urine samples
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Urinary Tract Infections
ADAPT-AST (Adaptive Antimicrobial Susceptibility Testing)
The goal of this study is to improve the way urinary tract infections (UTIs) are tested for antibiotic resistance. The main questions it aims to answer are: Can the investigators use a method called Bayesian causal inference to…
- Trial name
- ADAPT-AST (NCT06297837)
- Where
- United Kingdom
- Volunteers
- 500,000 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Interstitial Cystitis, Chronic, Overactive Bladder Syndrome
Real-life Clinical Experience With Ialuadapter Study
A retrospective study from a single center was performed. Quantitative and qualitative data was obtained on the use of the syringe adapter (IALUADAPTER®) in 61 patients with IC/BPS (n=48), rUTI (n=6) and mixed /other diagnoses…
- Conditions
- Interstitial Cystitis, Chronic, Overactive Bladder Syndrome, Recurrent Urinary Tract Infection
- Trial name
- Ialuadapter (NCT06540248)
- Testing
- Ialuadapter
- Where
- Netherlands
- Volunteers
- 61 people
- Sponsor
- Radboud University Medical Center
Urinary Schistosomiasis
Activity of Mefloquine Against Urinary Schistosomiasis
Urinary schistosomiasis is a debilitating disease in Central Africa and pregnant women are frequently suffering from this condition.
- Trial name
- NCT01132248
- Testing
- Mefloquine, S/P
- Where
- 2 sites in Gabon
- Volunteers
- 65 people
- Sponsor
- Albert Schweitzer Hospital
Schistosomiasis Haematobia
The Chinese-made Praziquantel for Treatment of Schistosoma Haematobium
Schistosomiasis remains an important parasitic disease in the tropics, special in Africa including Zanzibar. The WHO-recommended strategy to eliminate schistosomiasis involves large-scale treatment of affected populations through…
- Trial name
- NCT03133832
- Testing
- Companion Tablet
- Where
- Tanzania
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jiangsu Institute of Parasitic Diseases
Acute Pyelonephritis, Complicated Urinary Tract Infection
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Meropenem-Vaborbactam in Children With Complicated Urinary Tract Infection, Including Acute Pyelonephritis
The primary objective of the study is to assess the safety and tolerability of meropenem-vaborbactam administered by intravenous (IV) infusion in children 3 months and above to less than 12 years with complicated urinary tract…
- Trial name
- NCT06672978
- Testing
- Meropenem-Vaborbactam, Antibiotics
- Where
- 26 sites in United States, Bulgaria and 4 more
- Volunteers
- 66 people
- Sponsor
- Rempex (a wholly owned subsidiary of Melinta Therapeutics, LLC)
Bloodstream Infection, Pneumonia, Bacterial
Development of Risk Score Model and Decision Tree Algorithm for Predicting Infections With CRKp in Colonized Patients
DETERMINE trial is a prospective multicenter multinational cohort study. This study will be carried out to predict the risk of bloodstream infections (BSIs) or other types of invasive infection with carbapenem resistant…
- Conditions
- Bloodstream Infection, Pneumonia, Bacterial, Intra-abdominal Infection, Urinary Tract Infections
- Trial name
- DETERMINE (NCT04229511)
- Testing
- Detection of CRKp colonization
- Where
- Turkey (Türkiye)
- Volunteers
- 520 people
- Sponsor
- SCARE (Study group for carbapenem resistance)
Urinary Tract Infection (Diagnosis)
Rapid Point-of-care Bacteriuria and Microbial Susceptibility for Women With Suspected Uncomplicated Urinary Tract Infections: Diagnostic Accuracy in General Practice.
In this study, adult women presenting at their general practitioner with a likely bladder infection (with symptoms like a burning sensation when urinating, pain in the lower abdomen, and frequent or urgent need to urinate) will…
- Trial name
- NCT06625268
- Where
- 2 sites in Germany
- Volunteers
- 200 people
- Sponsor
- Wuerzburg University Hospital
Prostate Cancer, Urinary Tract Infection
Antibiotic Prophylaxis for Urinary Catheter Removal After Radical Prostatectomy
The aim of this study is to determine whether antibiotics prophylaxis at the time of urinary catheter removal decreases the number of symptomatic urinary tract infections in patients after radical prostatectomy.
- Conditions
- Prostate Cancer, Urinary Tract Infection, Clostridium Difficile
- Trial name
- Abx (NCT02247960)
- Testing
- Ciprofloxacin
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- University of Rochester
Urinary Tract Infection (UTI), Complicated Urinary Tract Infection
Study of Ceftolozane/Tazobactam (MK-7625A) in Japanese Participants With Uncomplicated Pyelonephritis and Complicated Urinary Tract Infection (MK-7625A-014)
This is a Phase 3, multi-site, non-randomized, open-label study evaluating the safety and efficacy of MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g) for the treatment of complicated urinary tract infection (cUTI) including…
- Conditions
- Urinary Tract Infection (UTI), Complicated Urinary Tract Infection, Pyelonephritis, Uncomplicated Pyelonephritis
- Trial name
- NCT02728089
- Testing
- MK-7625A 1.5 g (ceftolozane 1 g/tazobactam 0.5 g)
- Volunteers
- 115 people
- Sponsor
- Merck Sharp & Dohme LLC
Pneumonia, Heart Failure
Hospitalization at Home: The Acute Care Home Hospital Program for Adults
The investigators propose a home hospital model of care that substitutes for treatment in an acute care hospital. Limited studies of the home hospital model have demonstrated that a sizeable proportion of acute care can be…
- Conditions
- Pneumonia, Heart Failure, Cellulitis, Urinary Tract Infections
- Trial name
- NCT02864420
- Testing
- Home hospitalization, Inpatient Hospitalization
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Brigham and Women's Hospital
Bacteriuria
Assessment of Infection Control, Practice Efficiency, and Health Economics of Sheathed Versus Standard Cystoscopy
The purpose of this research study is to compare the effectiveness and efficiency of using a sterile sheath (EndoSheath®) during cystoscopy versus a standard scope.
- Trial name
- NCT02922868
- Testing
- EndoSheath CST-5000 Scope, Olympus Visera Elite OTV-S190 Scope
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Urinary Tract Infection
Safety and Tolerability of Ertapenem Sodium in the Treatment of Complicated Urinary Tract Infections (0826-055)
The purpose of this study is to determine the efficacy of ertapenem sodium (Invanz) in treatment of complicated urinary tract infections with respect to the proportion of patients with a favorable microbiological response at 5-9…
- Trial name
- NCT01014013
- Testing
- ertapenem sodium (MK0826), Comparator: ceftriaxone sodium
- Volunteers
- 271 people
- Sponsor
- Merck Sharp & Dohme LLC
Urinary Tract Infections
Single Dose Aminoglycosides for Acute Uncomplicated Cystitis in the Emergency Department Setting
The purpose of this research study is to determine if gentamicin is as effective treatment of acute uncomplicated cystitis (urinary tract infection) using aminoglycosides versus the current standards of care.
- Trial name
- NCT05702762
- Testing
- Gentamicin, Standard of Care
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mercy Health Ohio
Catheter-Associated Urinary Tract Infections, Urinary Catheterization
Anti-fouling Silicone Urinary Catheter for Adults Needing Long-term Catheterisation: a Pilot and Feasibility Study
This single-centre randomised pilot and feasibility study assessed whether an anti-fouling zwitterionic silicone urinary catheter can be deployed and evaluated in frail, elderly adults who require long-term indwelling…
- Conditions
- Catheter-Associated Urinary Tract Infections, Urinary Catheterization, Biofilms
- Trial name
- NCT07759986
- Testing
- Anti-fouling zwitterionic silicone urinary catheter, Conventional silicone urinary catheter
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Urinary Tract Infection
The Role of TLR-4 Polymorphisms in Children With Urinary Track Infections
Purpose So far anatomical abnormalities (mostly congenital) were, in the majority of the patients, associated with urinary track infections.
- Trial name
- TLR-4 (NCT02021305)
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Otorhinolaryngologic Diseases, Respiratory Tract Infections
Antibiotic Education for Children in an Emergency Care Unit
The purpose of this study is to determine if a patient education in acute condition about the intake of oral solution antibiotic in children under 6 year-old are effective to improve the satisfaction about the therapeutic…
- Conditions
- Otorhinolaryngologic Diseases, Respiratory Tract Infections, Pyelonephritis, Urinary Tract Infections
- Trial name
- ACHEEN (NCT00948779)
- Testing
- antibiotic education for children in an emergency care unit
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer
Postoperative Patient Comfort and Quality of Micturition in Suprapubic Tube vs. Transurethral Catheterization After RARP
The purpose of the study is to determine, whether the postoperative quality of micturition and continence can be improved depending on the urinary drainage catheter and retention after robot assisted radical prostatectomy.
- Trial name
- MPH (NCT02812173)
- Testing
- suprapubic tube ex 2 day, suprapubic tube ex 5 day, transurethral catheter ex 5 day
- Where
- Germany
- Volunteers
- 234 people
- Sponsor
- St. Antonius Hospital Gronau
Upper Respiratory Tract Infections, Urinary Tract Infections
Routine Prescription Feedback and Peer Comparison to Lower Antibiotic Prescriptions in Primary Care
To evaluate the effect of a continuous postal and web-based feedback and peer comparison system of individual antibiotic prescription rates on the prescription behaviour of primary care physicians in Switzerland.
- Trial name
- NCT01773824
- Testing
- Antibiotic prescription feedback, No Feedback
- Where
- Switzerland
- Volunteers
- 2,900 people
- Sponsor
- University Hospital, Basel, Switzerland