Clinical trials: Urinary Tract Infection (UTI)
Urinary Tract Infections
UTI Reference Standard: Delphi Method
This study is set up by an international core group consisting of infectious disease specialists, geriatricians, urologists, microbiologists, emergency physicians and primary care physicians to develop a consensus-based research…
- Trial name
- ORACLE (NCT05365906)
- Testing
- Delphi-procedure consisting of four survey rounds
- Where
- Netherlands
- Volunteers
- 47 people
- Sponsor
- Leiden University Medical Center
Urinary Catheterization, Urinary Tract Infections
Impact of Atkinson Product Design Urinary Slide Valve Versus Standard Catheter Drainage System on Social Functioning
The primary objective of this study is to evaluate the impact of the Atkinson Product Design urinary slide valve on patient morbidity and freedom as measured by impact on activities of daily living (ADL) and quality of life…
- Trial name
- NCT01063452
- Testing
- Truvalve, Control (catheter drainage bag)
- Where
- 2 sites in United States
- Sponsor
- The Cleveland Clinic
Spinal Cord Injuries (SCI), Neurogenic Bladder
Intravesical Lactobacillus Crispatus: Clinical Safety and Microbiome Evaluation
The goal of this clinical trial is to determine whether Lactobacillus crispatus strains isolated from the lower urinary tracts of adult women can be used as an antibiotic-sparing treatment for urinary symptoms and urinary tract…
- Conditions
- Spinal Cord Injuries (SCI), Neurogenic Bladder, Urinary Tract Infection (Diagnosis)
- Trial name
- NCT07308808
- Testing
- Lactobacillus Crispatus, Saline bladder wash
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medstar Health Research Institute
Urinary Tract Infections in Children, Dexamethasone
Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children
Urinary tract infection (UTI) is the most frequently occurring serious bacterial infection in young children and accounts 5 to 14% of emergency department visits Formation of renal scarring in children has been associated with…
- Conditions
- Urinary Tract Infections in Children, Dexamethasone, Kidney Scarring, Acute Pyelonephritis
- Trial name
- NCT04654507
- Testing
- Dexamethasone Oral
- Where
- Qatar
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Dementia, Depression
Vegetarian Diet and Chronic Degenerative Diseases
To investigate the prospective association between a vegetarian diet and chronic degenerative diseases in two cohorts of Taiwanese Buddhists
- Conditions
- Dementia, Depression, Cardiovascular Diseases, Stroke
- Trial name
- NCT03470584
- Testing
- Diet Exposure
- Where
- Taiwan
- Volunteers
- 18,064 people, healthy volunteers welcome
- Sponsor
- Dalin Tzu Chi General Hospital
Urinary Retention Postoperative, Postoperative Urinary Tract Infection
Early Patient Removal of Urinary Catheters After Urogynecologic Surgery
Management of postoperative urinary retention often requires the use of indwelling catheters. In a previous study, the investigators determined that patient removal of catheters at home is non-inferior to standard office removal…
- Conditions
- Urinary Retention Postoperative, Postoperative Urinary Tract Infection, Catheter Site Pain
- Trial name
- CARES2 (NCT06344884)
- Testing
- Early catheter removal
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Neurogenic Bladder, Catheter-Related Infections
Antiseptic-coated Intermittent Urinary Catheter
Study design is a prospective, randomised, double-blind, and interventional. Primary aim of the study is to investigate efficacy of antiseptic-coated intermittent hydrophilic urinary catheters in prevention and reduction of…
- Trial name
- GuardianCath (NCT02697162)
- Testing
- Antiseptic-coated catheter, Hydrophilic catheter, Octenidine chloride
- Where
- Croatia
- Sponsor
- Children's Hospital Zagreb
Urinary Tract Infections, Urinary Tract Infection (UTI)
Alternative Prophylaxis in Female Recurrent Urinary Tract Infections
Urological pathogens are effected by rising antimicrobial resistance rates due to the frequent use of antimicrobials for treatment and prophylaxis.
- Trial name
- AlP-FrUiT (NCT04095572)
- Testing
- intravesical instillation with HA-CS, intravesical instillation of sterile purified water
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- University Hospital, Basel, Switzerland
Spinal Cord Injuries, Urinary Tract Infections
Immunomodulation Therapy for Urinary Tract Infections
Urinary tract infections (UTI) represent one of the most common morbidities in individuals with spinal cord injury (SCI) and reason for re-hospitalization.
- Trial name
- UROVAXOM-P (NCT04049994)
- Testing
- Uro-Vaxom
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Urinary Tract Infections
Low Dose Estriol With Lactobacilli Treatment for Preventing Recurrent Urinary Tract Infection in Postmenopausal Women
Recurrent urinary tract infections (UTI) are a problem for postmenopausal women. The aim of this trial is to evaluate the effectiveness of lactobacilli in combination with low dose estriol for preventing recurrent urinary tract…
- Trial name
- NCT00900653
- Testing
- Gynoflor E (low dose estriol with lactobacillus)
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Yonsei University
Urinary Tract Infection
Evaluation of a Novel Midstream Urine Collection Technique for Infants in the Emergency Department
Urinalysis and urine culture are commonly employed laboratory tests in the Emergency Department (ED), particularly for the purposes of investigating febrile infants in whom bacterial etiologies must be ruled out.
- Trial name
- NCT02381834
- Testing
- Bladder stimulation technique
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Children's Hospital of Eastern Ontario
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years
The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placebo in the prevention of the first invasive extraintestinal pathogenic Escherichia…
- Trial name
- NCT04899336
- Testing
- ExPEC9V
- Where
- 374 sites in United States, Australia and 19 more
- Volunteers
- 17,797 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Posterior Urethral Valves
Efficacy and Safety of Circumcision Alone on Risk of Febrile Urinary Tract Infections in Boys With Posterior Urethral Valves: a Prospective Randomized Open-label Multicentric Trial Enriched With Historic Controls.
Boys with posterior urethral valves (PUV) are at increased risk of developing febrile urinary tract infections (fUTIs). As shown in the CIRCUP trial, circumcision plus antibiotic prophylaxis reduces the risk of FUTIs compared…
- Trial name
- CIRCUP 2 (NCT07527442)
- Testing
- Antibiotics strategy, Circumcision
- Where
- 13 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Critical Illness, Burns
Effect of Active Drain Line Clearance on Catheter-Associated Bacteriuria
Catheter-associated urinary tract infections (CAUTI) are the most common nosocomial infections in critically ill patients and are responsible for high morbidity rates, increased hospital stays and associated costs.
- Conditions
- Critical Illness, Burns, Surgery, Urinary Tract Infections
- Trial name
- CAB (NCT03816384)
- Testing
- Standard of Care, DLC Group, DLCS Group
- Sponsor
- Potrero Medical
Urinary Tract Infections
The Role of Probiotics in Preventing Recurrent Urinary Tract Infections in Pregnant Women
Urinary tract infections (UTIs) are a significant public health problem affecting more than 150 million people worldwide and causing a significant economic impact of approximately US$ 6 billion annually.
- Trial name
- NCT06429358
- Testing
- Lactobacillus rhamnosus, Control Group
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Frontier Medical and Dental College, Abbotabad
Urinary Tract Infection (Diagnosis), Pregnancy
Cross-sectional Study of the Prevalence and Risk Factors of Asymptomatic Bacteriuria in Pregnancy
Asymptomatic bacteriuria (ASB) is the presence of bacteria in the urine without symptoms of urinary tract infection. It is common during pregnancy and, if left untreated, may lead to complications such as pyelonephritis, preterm…
- Trial name
- NCT07001579
- Where
- Nepal
- Volunteers
- 390 people
- Sponsor
- Nepalese Army Institute of Health Sciences
Bacterial Colonization in Double J Ureteral Stent
Risk Factors for Bacterial Stent Colonization in Patients With a Double J Ureteral Stent
The goal of this prospective study is to identify the risk factors associated with bacterial colonization of DJS and report the common microorganisms isolated and drug susceptibility pattern.
- Trial name
- NCT06510790
- Testing
- Double J stent
- Where
- Nepal
- Volunteers
- 48 people
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.
Intermittent Urethral Catheterization, Spinal Dysraphism
The Effect of Nursing Interventions for Clean Intermittent Catheterization Caregivers and Child
In neurogenic or non-neurogenic bladder disorders, the removal process after the catheter is inserted into the bladder and the urine has been drained is called Clean intermittent catheterization (CIC).
- Conditions
- Intermittent Urethral Catheterization, Spinal Dysraphism, Urinary Tract Infections
- Trial name
- NCT04763382
- Testing
- experimental group: Training of caregivers, Control gruop
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Urinary Tract Infection Lower Acute
Efficacy and Tolerability of a Phytotherapy Combination (Aqualibra) in Patients With Uncomplicated Cystitis
This randomized, placebo-controlled, double-blind study investigated the efficacy and safety of the herbal medicinal product containing a combination of extracts of restharrow root (Ononidis radix), Java tea (Orthosiphonis…
- Trial name
- AquUTI (NCT04032574)
- Testing
- Herbal Medicinal Product
- Volunteers
- 200 people
- Sponsor
- Medice Arzneimittel Pütter GmbH & Co KG
Urinary Tract Infections
A Study to Evaluate Gepotidacin Exposure in Breast Milk of Healthy Lactating Women
This study aims to evaluate the pharmacokinetic of gepotidacin in fed healthy lactating women.
- Trial name
- NCT07645235
- Testing
- Gepotidacin
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline